EP4101933A4 - Korrekturverfahren für einzellige rna-seq-analysedatensätze, analyseverfahren für einzellige rna-seq, analyseverfahren für zelltyp-verhältnisse und vorrichtungen und computerprogramme zur ausführung dieser verfahren - Google Patents

Korrekturverfahren für einzellige rna-seq-analysedatensätze, analyseverfahren für einzellige rna-seq, analyseverfahren für zelltyp-verhältnisse und vorrichtungen und computerprogramme zur ausführung dieser verfahren Download PDF

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Publication number
EP4101933A4
EP4101933A4 EP21751230.0A EP21751230A EP4101933A4 EP 4101933 A4 EP4101933 A4 EP 4101933A4 EP 21751230 A EP21751230 A EP 21751230A EP 4101933 A4 EP4101933 A4 EP 4101933A4
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EP
European Patent Office
Prior art keywords
seq
cell
analysis
analysis method
cell rna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP21751230.0A
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English (en)
French (fr)
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EP4101933A1 (de
Inventor
Narutoku SATO
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Karydo TherapeutiX Inc
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Karydo TherapeutiX Inc
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Publication date
Application filed by Karydo TherapeutiX Inc filed Critical Karydo TherapeutiX Inc
Publication of EP4101933A1 publication Critical patent/EP4101933A1/de
Publication of EP4101933A4 publication Critical patent/EP4101933A4/de
Withdrawn legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809Methods for determination or identification of nucleic acids involving differential detection
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20Supervised data analysis

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Evolutionary Biology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Data Mining & Analysis (AREA)
  • Bioethics (AREA)
  • Artificial Intelligence (AREA)
  • Software Systems (AREA)
  • Evolutionary Computation (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Public Health (AREA)
  • Databases & Information Systems (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP21751230.0A 2020-02-06 2021-02-06 Korrekturverfahren für einzellige rna-seq-analysedatensätze, analyseverfahren für einzellige rna-seq, analyseverfahren für zelltyp-verhältnisse und vorrichtungen und computerprogramme zur ausführung dieser verfahren Withdrawn EP4101933A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2020018989 2020-02-06
PCT/JP2021/004470 WO2021157739A1 (ja) 2020-02-06 2021-02-06 シングルセルRNA-Seq解析のカウントデータセットの補正方法、シングルセルRNA-Seqの解析方法、細胞種の構成比率の解析方法、並びにこれらの方法を実行するための装置及びコンピュータプログラム

Publications (2)

Publication Number Publication Date
EP4101933A1 EP4101933A1 (de) 2022-12-14
EP4101933A4 true EP4101933A4 (de) 2024-02-28

Family

ID=77199636

Family Applications (1)

Application Number Title Priority Date Filing Date
EP21751230.0A Withdrawn EP4101933A4 (de) 2020-02-06 2021-02-06 Korrekturverfahren für einzellige rna-seq-analysedatensätze, analyseverfahren für einzellige rna-seq, analyseverfahren für zelltyp-verhältnisse und vorrichtungen und computerprogramme zur ausführung dieser verfahren

Country Status (6)

Country Link
US (1) US20230074644A1 (de)
EP (1) EP4101933A4 (de)
JP (1) JP7689737B2 (de)
CA (1) CA3170368A1 (de)
IL (1) IL295227A (de)
WO (1) WO2021157739A1 (de)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019018684A1 (en) * 2017-07-21 2019-01-24 The Board Of Trustees Of The Leland Stanford Junior University SYSTEMS AND METHODS FOR ANALYZING MIXED CELL POPULATIONS

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019018684A1 (en) * 2017-07-21 2019-01-24 The Board Of Trustees Of The Leland Stanford Junior University SYSTEMS AND METHODS FOR ANALYZING MIXED CELL POPULATIONS

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
KANG KAI ET AL: "CDSeq: A novel complete deconvolution method for dissecting heterogeneous samples using gene expression data", PLOS COMPUTATIONAL BIOLOGY, vol. 15, no. 12, 2 December 2019 (2019-12-02), US, pages 1 - 12, XP055845890, ISSN: 1553-7358, [retrieved on 20240118], DOI: 10.1371/journal.pcbi.1007510 *
MONACO GIANNI ET AL: "RNA-Seq Signatures Normalized by mRNA Abundance Allow Absolute Deconvolution of Human Immune Cell Types", CELL REPORTS, vol. 26, no. 6, 5 February 2019 (2019-02-05), US, pages 1627 - 1640.e7, XP055816150, ISSN: 2211-1247, DOI: 10.1016/j.celrep.2019.01.041 *
See also references of WO2021157739A1 *
VALLEJOS CATALINA A ET AL: "Normalizing single-cell RNA sequencing data: challenges and opportunities", vol. 14, no. 6, 15 May 2017 (2017-05-15), New York, pages 565 - 571, XP093121078, ISSN: 1548-7091, Retrieved from the Internet <URL:http://www.nature.com/articles/nmeth.4292> [retrieved on 20240118], DOI: 10.1038/nmeth.4292 *

Also Published As

Publication number Publication date
US20230074644A1 (en) 2023-03-09
WO2021157739A1 (ja) 2021-08-12
CA3170368A1 (en) 2021-08-12
EP4101933A1 (de) 2022-12-14
IL295227A (en) 2022-10-01
JP7689737B2 (ja) 2025-06-09
JPWO2021157739A1 (de) 2021-08-12

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