EP4326253A4 - Limitation de la croissance de cellules souches cancéreuses par le cannabis dans des cancers peu différenciés - Google Patents

Limitation de la croissance de cellules souches cancéreuses par le cannabis dans des cancers peu différenciés

Info

Publication number
EP4326253A4
EP4326253A4 EP22792179.8A EP22792179A EP4326253A4 EP 4326253 A4 EP4326253 A4 EP 4326253A4 EP 22792179 A EP22792179 A EP 22792179A EP 4326253 A4 EP4326253 A4 EP 4326253A4
Authority
EP
European Patent Office
Prior art keywords
cancer
cannabis
stem cell
cell growth
limit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP22792179.8A
Other languages
German (de)
English (en)
Other versions
EP4326253A1 (fr
Inventor
Anahid Jewett
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
University of California Berkeley
University of California San Diego UCSD
Original Assignee
University of California
University of California Berkeley
University of California San Diego UCSD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California, University of California Berkeley, University of California San Diego UCSD filed Critical University of California
Publication of EP4326253A1 publication Critical patent/EP4326253A1/fr
Publication of EP4326253A4 publication Critical patent/EP4326253A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/658—Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/5759—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Mycology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP22792179.8A 2021-04-19 2022-03-29 Limitation de la croissance de cellules souches cancéreuses par le cannabis dans des cancers peu différenciés Withdrawn EP4326253A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163176581P 2021-04-19 2021-04-19
PCT/US2022/022262 WO2022225658A1 (fr) 2021-04-19 2022-03-29 Limitation de la croissance de cellules souches cancéreuses par le cannabis dans des cancers peu différenciés

Publications (2)

Publication Number Publication Date
EP4326253A1 EP4326253A1 (fr) 2024-02-28
EP4326253A4 true EP4326253A4 (fr) 2025-05-21

Family

ID=83602014

Family Applications (1)

Application Number Title Priority Date Filing Date
EP22792179.8A Withdrawn EP4326253A4 (fr) 2021-04-19 2022-03-29 Limitation de la croissance de cellules souches cancéreuses par le cannabis dans des cancers peu différenciés

Country Status (4)

Country Link
US (1) US20220331286A1 (fr)
EP (1) EP4326253A4 (fr)
CA (1) CA3214348A1 (fr)
WO (1) WO2022225658A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202325306A (zh) * 2021-09-02 2023-07-01 美商天恩治療有限公司 改良免疫細胞之生長及功能的方法
AU2022376836A1 (en) 2021-10-26 2024-05-23 Dove Innovation Pty Limited Methods of treating head and neck cancers with hemp extract
EP4422769A2 (fr) 2021-10-26 2024-09-04 Ecofibre USA Inc. Systèmes et procédés pour produire des compositions et des extraits de chanvre
CA3235074A1 (fr) 2021-10-26 2023-05-04 Alexandra M CAPANO Methodes de traitement du cancer de l'ovaire par un extrait de chanvre
IL312245A (en) 2021-10-26 2024-06-01 Ecofibre Usa Inc Methods of treating endometriosis and other non-cancerous gynecological disorders with hemp extract
US20250332180A1 (en) * 2022-05-17 2025-10-30 The Regents Of The University Of California Cannabinoids and il-15 activate nk cells
CN119537618B (zh) * 2022-06-28 2025-10-24 北京字跳网络技术有限公司 媒体内容展示方法、装置、设备、存储介质及产品
EP4608426A1 (fr) 2022-10-26 2025-09-03 Ecofibre USA Inc. Compositions stabilisées comprenant du cannabidiol
IL320517A (en) 2022-10-26 2025-06-01 Ecofibre Usa Inc Methods for treating estrogen-sensitive diseases with cannabis extract

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022056086A1 (fr) * 2020-09-09 2022-03-17 The Regents Of The University Ofcalifornia Cannabis empêchant l'inactivation des nk dans le cancer et augmentant la fonction nk

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2471987B (en) * 2008-06-04 2012-02-22 Gw Pharma Ltd Anti-tumoural effects of cannabinoid combinations
US9254272B2 (en) * 2011-11-30 2016-02-09 Sutter West Bay Hospitals Resorcinol derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022056086A1 (fr) * 2020-09-09 2022-03-17 The Regents Of The University Ofcalifornia Cannabis empêchant l'inactivation des nk dans le cancer et augmentant la fonction nk

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
FIORE DONATELLA ET AL: "Rimonabant Kills Colon Cancer Stem Cells without Inducing Toxicity in Normal Colon Organoids", FRONTIERS IN PHARMACOLOGY, vol. 8, 4 January 2018 (2018-01-04), CH, pages Art 949, XP093238830, ISSN: 1663-9812, DOI: 10.3389/fphar.2017.00949 *
KO MENG-WEI ET AL: "Synthetic cannabinoid WIN 55,212-2 inhibits growth and induces cell death of oral and pancreatic stem-like/poorly differentiated tumor cells", ADVANCES IN CANCER BIOLOGY - METASTASIS, vol. 5, 19 May 2022 (2022-05-19), pages 100043, XP093238936, ISSN: 2667-3940, DOI: 10.1016/j.adcanc.2022.100043 *
KOZLOWSKA ANNA ET AL: "Differentiation by NK cells is a prerequisite for effective targeting of cancer stem cells/poorly differentiated tumors by chemopreventive and chemotherapeutic drugs", JOURNAL OF CANCER, vol. 8, no. 4, 11 February 2017 (2017-02-11), AU, pages 537 - 554, XP093239340, ISSN: 1837-9664, DOI: 10.7150/jca.15989 *
LAH TAMARA T. ET AL: "Cannabigerol Is a Potential Therapeutic Agent in a Novel Combined Therapy for Glioblastoma", CELLS, vol. 10, no. 2, 5 February 2021 (2021-02-05), pages 1 - 21, XP055976352, DOI: 10.3390/cells10020340 *
See also references of WO2022225658A1 *

Also Published As

Publication number Publication date
US20220331286A1 (en) 2022-10-20
CA3214348A1 (fr) 2022-10-27
WO2022225658A1 (fr) 2022-10-27
EP4326253A1 (fr) 2024-02-28

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