EP4339111A1 - Dispositif et procédé de remplissage de sacs - Google Patents

Dispositif et procédé de remplissage de sacs Download PDF

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Publication number
EP4339111A1
EP4339111A1 EP22195250.0A EP22195250A EP4339111A1 EP 4339111 A1 EP4339111 A1 EP 4339111A1 EP 22195250 A EP22195250 A EP 22195250A EP 4339111 A1 EP4339111 A1 EP 4339111A1
Authority
EP
European Patent Office
Prior art keywords
bag
dosing needle
connecting element
filling
dosing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP22195250.0A
Other languages
German (de)
English (en)
Inventor
Jörg Rosenland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Harro Hofliger Verpackungsmaschinen GmbH
Original Assignee
Harro Hofliger Verpackungsmaschinen GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harro Hofliger Verpackungsmaschinen GmbH filed Critical Harro Hofliger Verpackungsmaschinen GmbH
Priority to EP22195250.0A priority Critical patent/EP4339111A1/fr
Priority to CN202311175858.7A priority patent/CN117699103A/zh
Priority to US18/465,271 priority patent/US20240083612A1/en
Priority to CA3212295A priority patent/CA3212295A1/fr
Publication of EP4339111A1 publication Critical patent/EP4339111A1/fr
Withdrawn legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B39/00—Nozzles, funnels or guides for introducing articles or materials into containers or wrappers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/003—Filling medical containers such as ampoules, vials, syringes or the like
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/003—Filling medical containers such as ampoules, vials, syringes or the like
    • B65B3/006—Related operations, e.g. scoring ampoules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/04—Methods of, or means for, filling the material into the containers or receptacles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B51/00—Devices for, or methods of, sealing or securing package folds or closures; Devices for gathering or twisting wrappers, or necks of bags
    • B65B51/10—Applying or generating heat or pressure or combinations thereof
    • B65B51/14—Applying or generating heat or pressure or combinations thereof by reciprocating or oscillating members
    • B65B51/146—Closing bags
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10—Bag-type containers

Definitions

  • the invention relates to a device and a method for filling bags, in particular for filling infusion bags with a liquid.
  • the infusion bags can be bags with only one chamber, but also multi-chamber bags.
  • Multi-chamber bags can, for example, also include a powder and a liquid chamber.
  • Infusion bags must generally be filled under special conditions (“low bio burden”) because the contents contained in the infusion bags are fed to a patient and therefore must not be contaminated.
  • low bio burden In the case of oxygen-sensitive ingredients, especially in the case of cancer drugs or infusions for parenteral nutrition, it may be necessary to fill the infusion bags under inert gas, as the liquid to be filled must not come into contact with oxygen in the air. Nitrogen is generally used as the inert gas. Some ingredients can be sterilized after bottling. In this case, an aseptic production process is not required. However, if subsequent sterilization is not possible, an aseptic production process must be carried out.
  • the bags usually have a filling hose through which the bags can be filled.
  • a dosing needle is inserted into the filling hose.
  • the dosing needle usually has at least one contour feature on its outer contour through which the elastic filling hose is expanded from the inside.
  • the filling hose then seals itself against the dosing needle due to its own tension.
  • Such a sealing of the filling hose against the dosing needle is necessary so that no liquid occurs during dosing can get between the dosing needle and the filling hose. Counterforces may occur while the bag is being filled. Therefore, the filling hose must be stretched so much at the contour features that the forces of the material tension are greater than the forces of the liquid.
  • the filling hose is usually stretched relatively significantly in length.
  • the filling hose then suddenly contracts again. This can result in product splashing into the surrounding area; It is also possible for the inside of the filling hose to become dirty.
  • hose pushers can be used.
  • the hose pushers actively push the filling hose away from the dosing needle, thereby reducing the risk of major expansion of the filling hose.
  • a short regassing can first be carried out. This is fundamentally possible when using a metering valve with connections for both the liquid and an inert gas. If, on the other hand, active regassing is not to be used during dosing, it must be ensured in another way that the dosing hose is ventilated. This can be particularly difficult when filling using “single-use” components.
  • the invention is based on the object of providing an improved device and an improved method for filling bags, which has the best possible seal of the bag against the dosing needle.
  • the device according to the invention for filling bags is given by the features of main claim 1.
  • the method according to the invention for filling bags is given by the features of independent claim 5.
  • the device according to the invention for filling a bag has a holding device for a bag and a dosing needle which can be inserted into a connecting element of the bag.
  • a sealing device is present by means of which the connecting element can be pressed against the dosing needle from the outside.
  • connection element there is no tension in the connection element, so that there are no splashes or other contamination when the connection element is removed from the dosing needle. This makes removing the connection element much easier.
  • the sealing device can have a plurality of clamping jaws.
  • the clamping jaws can be pressed against the connecting element from the outside in order to seal it against the dosing needle.
  • the clamping jaws can be controlled individually, so that adaptation to different sizes of connection elements is possible.
  • the number of clamping jaws can be freely selected depending on the material of the connecting element and the respective size of the connecting element.
  • the outer diameter of the dosing needle can be slightly smaller than the inner diameter of the connecting element. In this way, after the sealing device has been loosened, an air gap can form between the dosing needle and the connecting element. This allows air to flow into the bag while the connecting element is being removed, which makes removing the connecting element much easier.
  • the connecting element of the bag can preferably be designed as a filling hose.
  • a dosing needle is first inserted into a connecting element of a bag.
  • the connecting element is then pressed against the dosing needle from the outside, so that the connecting element is sealed against the dosing needle. As soon as the seal has been completed, the bag can be filled.
  • the seal of the connection element against the dosing needle can be removed after the bag has been filled.
  • This allows an air gap to initially form between the dosing needle and the connecting element, through which air can flow into the bag. This makes it easier to remove the connecting element from the dispensing needle.
  • the connecting element can be closed, in particular sealed.
  • a closure using a stopper for example, is also possible.
  • the device 10 according to the invention for filling bags 12 is in Fig. 1 and 2 shown.
  • the bag 12 is designed as an infusion bag.
  • the device 10 has a dosing needle 14 and a holding device 16 for the infusion bag 12.
  • the free end 20 of the dosing needle 14 can be inserted into a connecting element 22 of an infusion bag 12, so that the liquid to be filled passes through the interior 24 of the dosing needle 14 into the infusion bag 12 can be filled.
  • the connecting element 22 of the infusion bag 12 is designed as a filling hose.
  • the dosing needle 14 can be attached via a connecting flange, not shown here, to a filling device, not shown here, in particular to a filling head.
  • the attachment can preferably take place via one or more screws.
  • the filling hose of the bag 12 can also be plugged directly onto the filling head of the filling device.
  • the filling head of the filling device serves as a dosing needle 14.
  • the dosing needle 14 has an approximately circular cross section.
  • the cross-sectional shape of the dosing needle 14, in particular the free end 20 of the dosing needle 14, can be freely selected in the device 10 according to the invention. This allows the free end 20 of the dosing needle 14 to be adapted to different connection elements 22 of an infusion bag 12 and to different cross-sectional shapes of the connection elements 22 of an infusion bag 12.
  • the dosing needle 14 can also have a rectangular, square or oval cross section, for example.
  • the free end 20 of the dosing needle 14 can be inserted a short distance into the filling hose 22.
  • the outer diameter 30 of the dosing needle 14 is slightly smaller than the inner diameter 32 of the filling hose 22. This creates a small air gap 34 between the dosing needle 14 and the filling hose 22. Through this air gap 34, air can enter the infusion bag 12 after the infusion bag 12 has been filled flow in, so that the filling hose 22 can be easily removed from the dosing needle 14.
  • the dosing needle 14 can also be easily and safely inserted into the filling hose 22 through the air gap 34.
  • a sealing device 40 with several clamping jaws 42 is present in the area of the filling hose 22.
  • the clamping jaws 32 can be adjusted perpendicular to the longitudinal direction 44 of the dosing needle 14, so that the clamping jaws 32 during the actual filling process (see Fig. 2 ) from the outside against the filling hose 22, so that the filling hose 22 lies tightly against the outside of the dosing needle 14. The filling hose 22 is thus sealed against the dosing needle 14.
  • the clamping jaws 32 are released again, so that the air gap 34 is formed again between the dosing needle 14 and the filling hose 22.
  • the infusion bag 12 can then be removed from the dosing needle 14 and closed.
  • the infusion bag 12 can in particular be sealed or closed using a stopper, for example.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Basic Packing Technique (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
EP22195250.0A 2022-09-13 2022-09-13 Dispositif et procédé de remplissage de sacs Withdrawn EP4339111A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP22195250.0A EP4339111A1 (fr) 2022-09-13 2022-09-13 Dispositif et procédé de remplissage de sacs
CN202311175858.7A CN117699103A (zh) 2022-09-13 2023-09-12 用于填充袋子的设备
US18/465,271 US20240083612A1 (en) 2022-09-13 2023-09-12 Device and method for filling bags
CA3212295A CA3212295A1 (fr) 2022-09-13 2023-09-13 Dispositif et methode pour remplir des sacs

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP22195250.0A EP4339111A1 (fr) 2022-09-13 2022-09-13 Dispositif et procédé de remplissage de sacs

Publications (1)

Publication Number Publication Date
EP4339111A1 true EP4339111A1 (fr) 2024-03-20

Family

ID=83318823

Family Applications (1)

Application Number Title Priority Date Filing Date
EP22195250.0A Withdrawn EP4339111A1 (fr) 2022-09-13 2022-09-13 Dispositif et procédé de remplissage de sacs

Country Status (4)

Country Link
US (1) US20240083612A1 (fr)
EP (1) EP4339111A1 (fr)
CN (1) CN117699103A (fr)
CA (1) CA3212295A1 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019057918A1 (fr) * 2017-09-22 2019-03-28 Fresenius Kabi Deutschland Gmbh Procédé de remplissage d'un emballage médical, dispositif de remplissage et emballage médical réalisé sous la forme d'un sachet
CN211943959U (zh) * 2020-02-29 2020-11-17 山东新华医疗器械股份有限公司 尾部灌装输液袋开灌封装置
EP3755299B1 (fr) * 2018-02-21 2022-03-30 Fresenius Medical Care Deutschland GmbH Dispositif et procédé de remplissage de poches de solution pour dialyse

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH345584A (fr) * 1956-07-20 1960-03-31 Plastus Sa Procédé pour la fermeture, par thermosoudage, de sachets en matière thermosoudable contenant un fluide, et appareil pour la mise en oeuvre de ce procédé
GB842927A (en) * 1956-07-20 1960-07-27 Plastus Sa Method of and means for filling bags of thermo-weldable material
FR1184576A (fr) * 1957-05-21 1959-07-23 Machine à conditionner des produits fluides dans des sachets en matière plastique
CH386912A (it) * 1963-01-17 1965-01-15 Centra Anstalt Macchina automatica per il riempimento dosato e la chiusura ermetica a ciclo continuo di sacchetti in materiale plastico
US3785410A (en) * 1972-06-28 1974-01-15 Carter Eng Co Method and apparatus for vacuum filling open mouth bags
DE69619008D1 (de) * 1995-03-31 2002-03-21 Eastman Kodak Co Vorrichtung zum Vakuumsiegeln von Beuteln
JP2937088B2 (ja) * 1995-09-27 1999-08-23 サンスター技研株式会社 高粘性材料充填方法並びにその方法に用いる充填装置
SE529607C2 (sv) * 2006-02-10 2007-10-02 Ecolean Res & Dev As Anordning för fyllning av en förpackning av kollapsande slag
SE534056C2 (sv) * 2008-07-02 2011-04-12 Ecolean Res & Dev As System för fyllning av förpackningar av kollapsande slag
CN103264780B (zh) * 2013-05-17 2014-10-29 四川科伦药业股份有限公司 软袋输液产品的药液灌装方法
DE102017006886A1 (de) * 2016-08-26 2018-03-01 Kiefel Gmbh VORRICHTUNG ZUM VERLÄNGERN EINER FOLIE UND ZUM VERSCHWEIßEN DER FOLIE MIT EINEM EINE ACHSRICHTUNG AUFWEISENDEN ANSCHLUSSTEIL SOWIE VERFAHREN, HERSTELLVERFAHREN, ANLAGE UND BEUTEL
CN210235384U (zh) * 2019-08-12 2020-04-03 青岛华元精细生物制品有限公司 用于粘稠液体输液袋罐装用灌装机
CN114940287B (zh) * 2022-04-06 2023-08-29 北京航天石化技术装备工程有限公司 一种自动夹袋机构及其使用方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019057918A1 (fr) * 2017-09-22 2019-03-28 Fresenius Kabi Deutschland Gmbh Procédé de remplissage d'un emballage médical, dispositif de remplissage et emballage médical réalisé sous la forme d'un sachet
EP3755299B1 (fr) * 2018-02-21 2022-03-30 Fresenius Medical Care Deutschland GmbH Dispositif et procédé de remplissage de poches de solution pour dialyse
CN211943959U (zh) * 2020-02-29 2020-11-17 山东新华医疗器械股份有限公司 尾部灌装输液袋开灌封装置

Also Published As

Publication number Publication date
US20240083612A1 (en) 2024-03-14
CA3212295A1 (fr) 2024-03-13
CN117699103A (zh) 2024-03-15

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