EP4436603A4 - Behandlung einer demyelinisierenden erkrankung des zentralen nervensystems (zns) mit sativizumab - Google Patents
Behandlung einer demyelinisierenden erkrankung des zentralen nervensystems (zns) mit sativizumabInfo
- Publication number
- EP4436603A4 EP4436603A4 EP22898636.0A EP22898636A EP4436603A4 EP 4436603 A4 EP4436603 A4 EP 4436603A4 EP 22898636 A EP22898636 A EP 22898636A EP 4436603 A4 EP4436603 A4 EP 4436603A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- sativizumab
- demyelinizing
- cns
- disease
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/JP2021/043459 WO2023095305A1 (en) | 2021-11-26 | 2021-11-26 | Treatment of a demyelinating disease of the central nervous system (cns) with satralizumab |
| PCT/JP2021/048257 WO2023119638A1 (en) | 2021-12-24 | 2021-12-24 | Treatment of a demyelinating disease of the central nervous system (cns) with satralizumab |
| PCT/JP2022/039605 WO2023095510A1 (en) | 2021-11-26 | 2022-10-25 | Treatment of a demyelinating disease of the central nervous system (cns) with satralizumab |
| PCT/JP2022/043453 WO2023095854A1 (en) | 2021-11-26 | 2022-11-25 | Treatment of a demyelinating disease of the central nervous system (cns) with satralizumab |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP4436603A1 EP4436603A1 (de) | 2024-10-02 |
| EP4436603A4 true EP4436603A4 (de) | 2026-04-08 |
Family
ID=86539582
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP22898636.0A Pending EP4436603A4 (de) | 2021-11-26 | 2022-11-25 | Behandlung einer demyelinisierenden erkrankung des zentralen nervensystems (zns) mit sativizumab |
Country Status (2)
| Country | Link |
|---|---|
| EP (1) | EP4436603A4 (de) |
| WO (1) | WO2023095854A1 (de) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI440469B (zh) * | 2008-09-26 | 2014-06-11 | Chugai Pharmaceutical Co Ltd | Improved antibody molecules |
| CA2972393A1 (en) * | 2015-02-27 | 2016-09-01 | Chugai Seiyaku Kabushiki Kaisha | Composition for treating il-6-related diseases |
-
2022
- 2022-11-25 EP EP22898636.0A patent/EP4436603A4/de active Pending
- 2022-11-25 WO PCT/JP2022/043453 patent/WO2023095854A1/en not_active Ceased
Non-Patent Citations (5)
| Title |
|---|
| ANONYMOUS CLINICALTRIALS ET AL: "Record History | ver. 12: 2022-11-21 | NCT05271409 | ClinicalTrials.gov", 21 November 2022 (2022-11-21), XP093324756, Retrieved from the Internet <URL:https://www.clinicaltrials.gov/study/NCT05271409?tab=history&a=12#version-content-panel> * |
| HEO YOUNG-A: "Satralizumab: First Approval", DRUGS, vol. 80, no. 14, 14 August 2020 (2020-08-14), Auckland, pages 1477 - 1482, XP93368542, ISSN: 0012-6667, Retrieved from the Internet <URL:https://pmc.ncbi.nlm.nih.gov/articles/PMC7522096/pdf/40265_2020_Article_1380.pdf> DOI: 10.1007/s40265-020-01380-2 * |
| RINGELSTEIN MARIUS ET AL: "Interleukin-6 Receptor Blockade in Treatment-Refractory MOG-IgG-Associated Disease and Neuromyelitis Optica Spectrum Disorders", NEUROLOGY - NEUROIMMUNOLOGY NEUROINFLAMMATION, vol. 9, no. 1, 16 November 2021 (2021-11-16), pages e1100, XP093068098, DOI: 10.1212/NXI.0000000000001100 * |
| See also references of WO2023095854A1 * |
| YAMAMURA TAKASHI ET AL: "Trial of Satralizumab in Neuromyelitis Optica Spectrum Disorder", NEW ENGLAND JOURNAL OF MEDICINE, vol. 381, no. 22, 28 November 2019 (2019-11-28), United States, pages 2114 - 2124, XP093321210, ISSN: 0028-4793, DOI: 10.1056/NEJMoa1901747 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2023095854A1 (en) | 2023-06-01 |
| EP4436603A1 (de) | 2024-10-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
| 17P | Request for examination filed |
Effective date: 20240604 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
| DAV | Request for validation of the european patent (deleted) | ||
| DAX | Request for extension of the european patent (deleted) | ||
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 39/395 20060101AFI20251022BHEP Ipc: A61K 31/52 20060101ALI20251022BHEP Ipc: A61K 31/5377 20060101ALI20251022BHEP Ipc: A61K 31/573 20060101ALI20251022BHEP Ipc: A61P 25/00 20060101ALI20251022BHEP Ipc: A61P 37/06 20060101ALI20251022BHEP |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20260309 |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 39/395 20060101AFI20260303BHEP Ipc: A61K 31/52 20060101ALI20260303BHEP Ipc: A61K 31/5377 20060101ALI20260303BHEP Ipc: A61K 31/573 20060101ALI20260303BHEP Ipc: A61P 25/00 20060101ALI20260303BHEP Ipc: A61P 37/06 20060101ALI20260303BHEP |