MA51738A - Composés pour le traitement de la douleur - Google Patents
Composés pour le traitement de la douleurInfo
- Publication number
- MA51738A MA51738A MA051738A MA51738A MA51738A MA 51738 A MA51738 A MA 51738A MA 051738 A MA051738 A MA 051738A MA 51738 A MA51738 A MA 51738A MA 51738 A MA51738 A MA 51738A
- Authority
- MA
- Morocco
- Prior art keywords
- pain
- compounds
- treatment
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862626499P | 2018-02-05 | 2018-02-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA51738A true MA51738A (fr) | 2021-05-12 |
Family
ID=65444375
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA051738A MA51738A (fr) | 2018-02-05 | 2019-02-04 | Composés pour le traitement de la douleur |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US10604489B2 (fr) |
| EP (1) | EP3749667A1 (fr) |
| JP (1) | JP2021512952A (fr) |
| KR (1) | KR20200136384A (fr) |
| CN (1) | CN111989327A (fr) |
| AU (1) | AU2019216522A1 (fr) |
| BR (1) | BR112020015712A2 (fr) |
| CA (1) | CA3090385A1 (fr) |
| EA (1) | EA202091881A1 (fr) |
| IL (1) | IL276482A (fr) |
| MA (1) | MA51738A (fr) |
| MX (1) | MX2020008195A (fr) |
| SG (1) | SG11202007422QA (fr) |
| WO (1) | WO2019152946A1 (fr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2021512952A (ja) * | 2018-02-05 | 2021-05-20 | アルカームス・インコーポレイテッド | 疼痛の処置のための化合物 |
| WO2021026377A1 (fr) * | 2019-08-07 | 2021-02-11 | Alkermes, Inc. | Composés contenant du lactame pour le traitement de la douleur |
| WO2021026380A1 (fr) * | 2019-08-07 | 2021-02-11 | Alkermes, Inc. | Composés de phényltriazole pour le traitement de la douleur |
| WO2021026375A1 (fr) * | 2019-08-07 | 2021-02-11 | Alkermes, Inc. | Composés bicycliques fusionnés pour le traitement de la douleur |
| WO2021026378A1 (fr) * | 2019-08-07 | 2021-02-11 | Alkermes, Inc. | Composés d'indole pour le traitement de la douleur |
| TW202142537A (zh) | 2020-02-04 | 2021-11-16 | 美商艾爾凱默斯公司 | ３－（（１Ｒ，５Ｓ，９ｒ）－９－乙氧基－３－氮雜雙環并［３．３．１］壬烷－９－基）—苯甲醯胺之結晶形式及其鹽形式 |
Family Cites Families (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3167562A (en) | 1965-01-26 | New j-azabicyclo | ||
| GB952137A (en) | 1961-03-14 | 1964-03-11 | Sankyo Co | New 3-azabicyclo [3.3.1] nonane compounds and a process for preparing these compounds |
| US3196154A (en) | 1962-05-17 | 1965-07-20 | Sterling Drug Inc | 3-substituted-9-methyl-3, 9-diazabicyclo [3.3.1] nonanes |
| US3475439A (en) | 1966-05-07 | 1969-10-28 | Sankyo Co | 3-azabicyclo(3.3.1)nonane compounds |
| GB1195746A (en) | 1967-06-07 | 1970-06-24 | Yoshitomi Pharmaceutical | 3-Azabicyclo [3,3,1] Nonane Derivatives |
| GB1393253A (en) | 1971-09-10 | 1975-05-07 | Wyeth John & Brother Ltd | 3-azabicyclo-3,3,1-nonanes |
| JPS4856680A (fr) | 1971-11-18 | 1973-08-09 | ||
| JPS4961168A (fr) | 1972-10-14 | 1974-06-13 | ||
| IL59004A0 (en) * | 1978-12-30 | 1980-03-31 | Beecham Group Ltd | Substituted benzamides their preparation and pharmaceutical compositions containing them |
| JPS5592384A (en) * | 1978-12-30 | 1980-07-12 | Beecham Group Ltd | Compound having pharmacological activity |
| CA2224047A1 (fr) | 1990-06-05 | 1991-12-06 | Toray Industries, Inc. | Derives indole |
| EP0483403A1 (fr) | 1990-10-31 | 1992-05-06 | Hoechst Aktiengesellschaft | Dérivés d'amino-acides ayant une activité d'inhibitrice de rénine, leur procédé de préparation et les médicaments les contenant |
| DE4341403A1 (de) | 1993-12-04 | 1995-06-08 | Basf Ag | N-substituierte 3-Azabicycloalkan-Derivate, ihre Herstellung und Verwendung |
| US5541217A (en) | 1995-05-17 | 1996-07-30 | Ortho Pharmaceutical Corporation | 4-arylcyclopenta[c]pyrrole analgesics |
| JP2808089B2 (ja) | 1995-08-29 | 1998-10-08 | レーザーテクノ株式会社 | 墨出し用レーザー装置 |
| TWI244481B (en) | 1998-12-23 | 2005-12-01 | Pfizer | 3-azabicyclo[3.1.0]hexane derivatives useful in therapy |
| DE19952146A1 (de) | 1999-10-29 | 2001-06-07 | Boehringer Ingelheim Pharma | Arylalkane, Arylalkene und Aryl-azaalkane, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| US6852716B2 (en) * | 2002-02-15 | 2005-02-08 | Pfizer Inc | Substituted-aryl compounds for treatment of disease |
| MXPA05011070A (es) * | 2003-04-14 | 2005-12-12 | Pfizer Prod Inc | Derivados de 3-azabiciclo [3.2.1] octano. |
| US7056930B2 (en) | 2003-04-14 | 2006-06-06 | Pfizer Inc. | 2-Azabicyclo[3.3.1]nonane derivatives |
| US20050043327A1 (en) * | 2003-08-21 | 2005-02-24 | Pfizer Inc | Pharmaceutical composition for the prevention and treatment of addiction in a mammal |
| PT1678172E (pt) | 2003-10-15 | 2010-03-03 | Targacept Inc | Composições farmacêuticas e métodos para alívio da dor e tratamento de perturbações do sistema nervoso central |
| JP2008503585A (ja) | 2004-06-22 | 2008-02-07 | シェーリング コーポレイション | カンナビノイドレセプターリガンド |
| WO2007029156A2 (fr) | 2005-09-05 | 2007-03-15 | Ranbaxy Laboratories Limited | Derives d'isoindoledione comme antagonistes de recepteurs adrenergiques |
| US7538110B2 (en) | 2005-10-27 | 2009-05-26 | Adolor Corporation | Opioid antagonists |
| CA2628403A1 (fr) | 2005-11-03 | 2007-05-18 | Activbiotics, Inc. | Analogues de la rifamycine et leurs utilisations |
| MY145633A (en) | 2006-03-01 | 2012-03-15 | Theravance Inc | 8-azabicyclo[3.2.1]octane compounds as mu opioid receptor antagonists |
| FR2918986B1 (fr) | 2007-07-19 | 2009-09-04 | Sanofi Aventis Sa | Derives de 6-cycloamino-3-(pyridazin-4-yl)imidazo[1,2-b]- pyridazine, leur preparation et leur application en therapeutique |
| TWI423801B (zh) | 2007-08-27 | 2014-01-21 | Theravance Inc | 作為μ類鴉片受體拮抗劑之８－氮雜雙環〔３．２．１〕辛基－２－羥基苯甲醯胺化合物 |
| US8048895B2 (en) | 2008-04-18 | 2011-11-01 | Research Triangle Institute | Kappa opioid receptor ligands |
| GB0815947D0 (en) | 2008-09-02 | 2008-10-08 | Univ Dundee | Compounds |
| EP2485735B1 (fr) | 2009-10-08 | 2015-07-29 | Merck Sharp & Dohme Corp. | Inhibiteurs de protéines de liaison aux acides gras (fabp) |
| FR2953839A1 (fr) | 2009-12-14 | 2011-06-17 | Sanofi Aventis | Nouveaux derives d'(heterocycle-piperidine condensee)-(piperazinyl)-1alcanone ou d'(heterocycle-pyrrolidine condensee)-(piperazinyl)-1alcanone et leur utilisation comme inhibiteurs de p75 |
| TW201209054A (en) | 2010-05-28 | 2012-03-01 | Prosidion Ltd | Novel compounds |
| HUE029196T2 (en) | 2010-06-04 | 2017-02-28 | Hoffmann La Roche | Aminoprimidine derivatives as LRRK2 modulators |
| WO2012075232A1 (fr) | 2010-12-04 | 2012-06-07 | Trevena, Inc. | Ligands de récepteurs opioïdes et procédés d'utilisation et de fabrication de ceux-ci |
| ME02754B (fr) | 2011-03-23 | 2018-01-20 | Trevena Inc | Ligands de récepteurs opïoides, et leurs procédés d'utilisation et de production |
| JP2014237589A (ja) | 2011-09-28 | 2014-12-18 | 日本曹達株式会社 | 環状アミン化合物および有害生物防除剤 |
| GB2498976A (en) | 2012-02-01 | 2013-08-07 | Prosidion Ltd | GPR119 agonists useful in the treatment of type II diabetes |
| JP2015083543A (ja) | 2012-02-14 | 2015-04-30 | 大日本住友製薬株式会社 | 新規縮環ピロリジン誘導体 |
| ES2779223T3 (es) * | 2012-10-08 | 2020-08-14 | Universität Ulm | Combinación de opioides y fármacos anticancerosos para el tratamiento del cáncer |
| WO2014194519A1 (fr) | 2013-06-07 | 2014-12-11 | Merck Sharp & Dohme Corp. | Dérivés imidazole et leurs procédés d'utilisation pour l'amélioration des propriétés pharmacocinétiques d'un médicament |
| US9840495B2 (en) | 2013-12-20 | 2017-12-12 | AbbVie Deutschland GmbH & Co. KG | Oxindole derivatives carrying a piperidyl-substituted azetidinyl substituent and use thereof for treating vasopressine-related diseases |
| NO2721710T3 (fr) | 2014-08-21 | 2018-03-31 | ||
| WO2018045229A1 (fr) | 2016-09-01 | 2018-03-08 | Mebias Discovery Llc | Urées substituées et leur procédés de préparation et d'utilisation |
| US10836728B2 (en) | 2017-01-17 | 2020-11-17 | Mebias Discovery, Inc. | Substituted 3-dialkylaminomethyl-piperidin-4-yl-benzamides and methods of making and using same |
| JP2021512952A (ja) * | 2018-02-05 | 2021-05-20 | アルカームス・インコーポレイテッド | 疼痛の処置のための化合物 |
-
2019
- 2019-02-04 JP JP2020564036A patent/JP2021512952A/ja active Pending
- 2019-02-04 WO PCT/US2019/016543 patent/WO2019152946A1/fr not_active Ceased
- 2019-02-04 KR KR1020207025543A patent/KR20200136384A/ko not_active Ceased
- 2019-02-04 EA EA202091881A patent/EA202091881A1/ru unknown
- 2019-02-04 MX MX2020008195A patent/MX2020008195A/es unknown
- 2019-02-04 SG SG11202007422QA patent/SG11202007422QA/en unknown
- 2019-02-04 EP EP19705893.6A patent/EP3749667A1/fr not_active Withdrawn
- 2019-02-04 CN CN201980021811.0A patent/CN111989327A/zh active Pending
- 2019-02-04 CA CA3090385A patent/CA3090385A1/fr active Pending
- 2019-02-04 US US16/267,025 patent/US10604489B2/en active Active
- 2019-02-04 AU AU2019216522A patent/AU2019216522A1/en not_active Abandoned
- 2019-02-04 BR BR112020015712-0A patent/BR112020015712A2/pt not_active Application Discontinuation
- 2019-02-04 MA MA051738A patent/MA51738A/fr unknown
-
2020
- 2020-02-13 US US16/790,224 patent/US11180455B2/en not_active Expired - Fee Related
- 2020-08-04 IL IL276482A patent/IL276482A/en unknown
-
2021
- 2021-10-12 US US17/499,686 patent/US20220033394A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN111989327A (zh) | 2020-11-24 |
| US10604489B2 (en) | 2020-03-31 |
| US20220033394A1 (en) | 2022-02-03 |
| AU2019216522A1 (en) | 2020-08-27 |
| IL276482A (en) | 2020-09-30 |
| US20190241524A1 (en) | 2019-08-08 |
| EA202091881A1 (ru) | 2020-11-10 |
| WO2019152946A1 (fr) | 2019-08-08 |
| EP3749667A1 (fr) | 2020-12-16 |
| JP2021512952A (ja) | 2021-05-20 |
| BR112020015712A2 (pt) | 2020-12-08 |
| CA3090385A1 (fr) | 2019-08-08 |
| US20200255383A1 (en) | 2020-08-13 |
| US11180455B2 (en) | 2021-11-23 |
| MX2020008195A (es) | 2020-11-24 |
| KR20200136384A (ko) | 2020-12-07 |
| SG11202007422QA (en) | 2020-09-29 |
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