EP4704805A2 - Orale lösung mit liothyronin-natrium - Google Patents

Orale lösung mit liothyronin-natrium

Info

Publication number
EP4704805A2
EP4704805A2 EP24722291.2A EP24722291A EP4704805A2 EP 4704805 A2 EP4704805 A2 EP 4704805A2 EP 24722291 A EP24722291 A EP 24722291A EP 4704805 A2 EP4704805 A2 EP 4704805A2
Authority
EP
European Patent Office
Prior art keywords
oral pharmaceutical
pharmaceutical solution
solution
solution according
sodium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24722291.2A
Other languages
English (en)
French (fr)
Inventor
Georgios Liolios
Konstantinos Pachis
Eirini Christodoulou
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Labomed Pharmaceutical Company SA
Original Assignee
Labomed Pharmaceutical Company SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labomed Pharmaceutical Company SA filed Critical Labomed Pharmaceutical Company SA
Publication of EP4704805A2 publication Critical patent/EP4704805A2/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP24722291.2A 2023-05-02 2024-05-02 Orale lösung mit liothyronin-natrium Pending EP4704805A2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP23386032 2023-05-02
PCT/EP2024/062153 WO2024227895A2 (en) 2023-05-02 2024-05-02 Oral solution comprising liothyronine sodium

Publications (1)

Publication Number Publication Date
EP4704805A2 true EP4704805A2 (de) 2026-03-11

Family

ID=86386779

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24722291.2A Pending EP4704805A2 (de) 2023-05-02 2024-05-02 Orale lösung mit liothyronin-natrium

Country Status (2)

Country Link
EP (1) EP4704805A2 (de)
WO (1) WO2024227895A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025245015A1 (en) * 2024-05-20 2025-11-27 Regents Of The University Of Minnesota Thyroid hormone prodrugs and compositions comprising the same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9401891D0 (en) 1994-02-01 1994-03-30 Boots Co Plc Therapeutic agents
US6190696B1 (en) 1998-06-08 2001-02-20 Pieter J. Groenewoud Stabilized thyroxine medications
ATE519480T1 (de) * 2006-01-06 2011-08-15 Intervet Int Bv Konzentrierte flüssige schilddrüsenhormonzusammensetzung
DK2683361T3 (da) * 2011-03-10 2016-02-01 Emp Pharma Gmbh Fremgangsmåde til fremstilling af en levothyroxinopløsning
WO2022221480A1 (en) * 2021-04-15 2022-10-20 Vertice Pharma Llc Stable liquid oral dosage forms of liothyronine

Also Published As

Publication number Publication date
WO2024227895A2 (en) 2024-11-07
WO2024227895A3 (en) 2024-12-26

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Legal Events

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