EP4788657A2 - Procédé amélioré pour la synthèse de tous les prénols (e)-hepta (c35-oh) - Google Patents

Procédé amélioré pour la synthèse de tous les prénols (e)-hepta (c35-oh)

Info

Publication number
EP4788657A2
EP4788657A2 EP24800932.6A EP24800932A EP4788657A2 EP 4788657 A2 EP4788657 A2 EP 4788657A2 EP 24800932 A EP24800932 A EP 24800932A EP 4788657 A2 EP4788657 A2 EP 4788657A2
Authority
EP
European Patent Office
Prior art keywords
octacosa
benzene
hexaen
heptamethyl
synthesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24800932.6A
Other languages
German (de)
English (en)
Inventor
Raju BNS
Priyanka NIPURTE
Komal KALE
Parin K VORA
Dilip Mehta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synergia Life Sciences Pvt Ltd
Original Assignee
Synergia Life Sciences Pvt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synergia Life Sciences Pvt Ltd filed Critical Synergia Life Sciences Pvt Ltd
Publication of EP4788657A2 publication Critical patent/EP4788657A2/fr
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/14—Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/16—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C317/18—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/02—Acyclic alcohols with carbon-to-carbon double bonds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La présente divulgation concerne un procédé amélioré pour la synthèse régiospécifique et stéréospécifique de composés polyprényles. Plus particulièrement, elle concerne la synthèse régiospécifique et stéréospécifique de (2E,6E,10E,14E,18E,22E)-3,7,11,15,19,23,27-heptaméthyloctacosa-2,6,10,14,18,22,26 heptane-1-ol qui trouve une utilisation dans la synthèse de vitamine K2-7.
EP24800932.6A 2023-10-05 2024-10-04 Procédé amélioré pour la synthèse de tous les prénols (e)-hepta (c35-oh) Pending EP4788657A2 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN202321066937 2023-10-05
IN202421009595 2024-02-13
PCT/IB2024/059716 WO2025074315A2 (fr) 2023-10-05 2024-10-04 Procédé amélioré pour la synthèse de tous les prénols (e)-hepta (c35-oh)

Publications (1)

Publication Number Publication Date
EP4788657A2 true EP4788657A2 (fr) 2026-08-12

Family

ID=93341603

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24800932.6A Pending EP4788657A2 (fr) 2023-10-05 2024-10-04 Procédé amélioré pour la synthèse de tous les prénols (e)-hepta (c35-oh)

Country Status (4)

Country Link
EP (1) EP4788657A2 (fr)
KR (1) KR20260088513A (fr)
CN (1) CN122029142A (fr)
WO (1) WO2025074315A2 (fr)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0759504B2 (ja) 1986-01-23 1995-06-28 エーザイ株式会社 ポリプレニルアルコ−ル含有注射剤
GB0817528D0 (en) 2008-09-24 2008-10-29 Syntavit As Process
GB201004876D0 (en) 2010-03-23 2010-05-05 Syntavit As Process for the preparation of vitamin K2
PL401195A1 (pl) * 2012-10-12 2014-04-14 Instytut Farmaceutyczny Sposób wytwarzania witaminy K2 w formie MK-7
US9464021B2 (en) 2013-11-01 2016-10-11 Dilip S. Mehta Method of preparation of stereospecific quinone derivatives
CN116813446B (zh) * 2023-06-26 2024-07-30 天津玉健生物工程有限公司 一种砜基化合物还原脱砜的方法

Also Published As

Publication number Publication date
CN122029142A (zh) 2026-05-12
WO2025074315A3 (fr) 2025-05-15
KR20260088513A (ko) 2026-06-12
WO2025074315A2 (fr) 2025-04-10

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