ES2000476A6 - Diazinylpiperidine derivatives - Google Patents

Diazinylpiperidine derivatives

Info

Publication number
ES2000476A6
ES2000476A6 ES8600190A ES8600190A ES2000476A6 ES 2000476 A6 ES2000476 A6 ES 2000476A6 ES 8600190 A ES8600190 A ES 8600190A ES 8600190 A ES8600190 A ES 8600190A ES 2000476 A6 ES2000476 A6 ES 2000476A6
Authority
ES
Spain
Prior art keywords
ring
alkyl
diazinylpiperidine
derivatives
pyridazine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8600190A
Other languages
Spanish (es)
Inventor
Ronald J Mattson
Joseph P Yevich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ES2000476A6 publication Critical patent/ES2000476A6/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Nootropic compounds of Formula I < IMAGE > wherein X is an ethylene chain or a 1,2-benzo ring Y is carbonyl or methylene R<1> is hydrogen or lower alkyl and Z is an R<2>, R<3>-disubstituted diazinyl ring selected from pyridazine, pyrimidine, and pyrazine ring systems, where R<2> and R<3> are selected from H, C1-4 alkyl, alkoxy or alkylthio, CN, CF3, C2F5 or halogen, possess cognition and memory enhancing activity.
ES8600190A 1985-07-08 1986-07-08 Diazinylpiperidine derivatives Expired ES2000476A6 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75300685A 1985-07-08 1985-07-08
US86846886A 1986-05-30 1986-05-30

Publications (1)

Publication Number Publication Date
ES2000476A6 true ES2000476A6 (en) 1988-03-01

Family

ID=27115677

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8600190A Expired ES2000476A6 (en) 1985-07-08 1986-07-08 Diazinylpiperidine derivatives

Country Status (28)

Country Link
KR (1) KR940003756B1 (en)
CN (1) CN1012364B (en)
AT (1) AT395850B (en)
AU (1) AU595215B2 (en)
BE (1) BE905061A (en)
CA (1) CA1272725A (en)
CH (1) CH671579A5 (en)
CY (1) CY1630A (en)
DE (1) DE3622842C2 (en)
DK (1) DK170441B1 (en)
EG (1) EG18310A (en)
ES (1) ES2000476A6 (en)
FI (1) FI88300C (en)
FR (1) FR2584408B1 (en)
GB (1) GB2177692B (en)
GR (1) GR861765B (en)
HK (1) HK11292A (en)
HU (1) HU199455B (en)
IE (1) IE59424B1 (en)
IL (1) IL79351A (en)
IT (1) IT1196467B (en)
NL (1) NL8601763A (en)
NO (1) NO167389C (en)
NZ (1) NZ216720A (en)
PT (1) PT82942B (en)
SE (1) SE462491B (en)
SG (1) SG111091G (en)
YU (2) YU45017B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0351283A1 (en) * 1988-07-12 1990-01-17 Synthelabo 2-[(4-Piperidinyl)methyl]-2,3-dihydro-1H-isoindole and 2,3,4,5-tetrahydro-1H-benzazepine derivatives, their preparation and therapeutical use
FR2634208B1 (en) * 1988-07-12 1990-11-23 Synthelabo ((PIPERIDINYL-4) METHYL) -2 DIHYDRO-2,3 1H-ISOINDOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
US5356906A (en) * 1989-10-27 1994-10-18 The Du Pont Merck Pharmaceutical Company (N-phthalimidoalkyl) piperidines useful as treatments for psychosis
HU206878B (en) * 1989-10-27 1993-01-28 Bristol Myers Squibb Co Process for producing 1-//1-/2-/trifluoromethyl/-4-pyrimidinyl/-4-piperidinyl/-methyl/-2-pirrolidinone
CA2069318A1 (en) * 1989-10-27 1991-04-28 Engelbert Ciganek (n-phthalimidoalkyl) piperidines
US5098904A (en) * 1990-06-27 1992-03-24 Bristol-Myers Squibb Company Cerebral function enhancing pyrimidinyl derivatives
US5240934A (en) * 1990-10-19 1993-08-31 Ss Pharmaceutical Co., Ltd. Quinoline derivatives
US5190951A (en) * 1990-10-19 1993-03-02 Ss Pharmaceutical Co., Ltd. Quinoline derivatives
US5401744A (en) * 1993-10-04 1995-03-28 Bristol-Myers Squibb Company Useful hemi-hydrate form of a cerebral function enhancing agent
CN106188039B (en) * 2016-06-30 2019-01-01 广东工业大学 A kind of derovatives and the preparation method and application thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759371A (en) * 1969-11-24 1971-05-24 Bristol Myers Co HETEROCYCLICAL AZASPIRODECANEDIONES AND METHODS FOR THEIR PREPARATION
ZA76475B (en) * 1975-03-10 1977-08-31 Ciba Geigy Ag Indolyalkylpiperidines
EP0009465A1 (en) * 1978-09-20 1980-04-02 Ciba-Geigy Ag N-(1-(4-amino-2-quinazolinyl)-3 or 4-piperidyl lactames, process for their preparation and pharmaceutical compositions containing them
US4423049A (en) * 1981-12-28 1983-12-27 Mead Johnson & Company 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyrimidines
US4524206A (en) * 1983-09-12 1985-06-18 Mead Johnson & Company 1-Heteroaryl-4-(2,5-pyrrolidinedion-1-yl)alkyl)piperazine derivatives

Also Published As

Publication number Publication date
CA1272725A (en) 1990-08-14
FI862830L (en) 1987-01-09
GR861765B (en) 1986-11-07
ATA185286A (en) 1992-08-15
GB2177692A (en) 1987-01-28
SG111091G (en) 1992-02-14
IE59424B1 (en) 1994-02-23
YU45017B (en) 1991-06-30
CN86104681A (en) 1987-05-27
NO167389C (en) 1991-10-30
PT82942A (en) 1986-08-01
HK11292A (en) 1992-02-21
NL8601763A (en) 1987-02-02
PT82942B (en) 1989-01-30
IT8621049A1 (en) 1988-01-07
GB8616504D0 (en) 1986-08-13
HUT41405A (en) 1987-04-28
SE462491B (en) 1990-07-02
IL79351A (en) 1990-03-19
DK170441B1 (en) 1995-09-04
YU107387A (en) 1988-04-30
IL79351A0 (en) 1986-10-31
CY1630A (en) 1992-07-10
DK323986D0 (en) 1986-07-07
DE3622842A1 (en) 1987-03-05
CH671579A5 (en) 1989-09-15
FI88300C (en) 1993-04-26
FI862830A0 (en) 1986-07-03
EG18310A (en) 1992-10-30
SE8603026D0 (en) 1986-07-07
SE8603026L (en) 1987-01-09
AU5978786A (en) 1987-01-15
IT1196467B (en) 1988-11-16
NZ216720A (en) 1990-09-26
AU595215B2 (en) 1990-03-29
KR870001197A (en) 1987-03-12
FI88300B (en) 1993-01-15
NO862729L (en) 1987-01-09
FR2584408B1 (en) 1989-06-02
GB2177692B (en) 1989-07-12
NO167389B (en) 1991-07-22
AT395850B (en) 1993-03-25
YU44947B (en) 1991-04-30
CN1012364B (en) 1991-04-17
FR2584408A1 (en) 1987-01-09
DK323986A (en) 1987-01-09
BE905061A (en) 1987-01-07
KR940003756B1 (en) 1994-04-30
HU199455B (en) 1990-02-28
YU118686A (en) 1988-04-30
DE3622842C2 (en) 1996-08-29
NO862729D0 (en) 1986-07-07
IE861826L (en) 1987-01-08
IT8621049A0 (en) 1986-07-07

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20060710