ES2000617A6 - Procedimiento para la preparacion de las sales no toxicas del 6-metil-3,4-dihidro-1,2,3-oxatiazin-4-on-2,2-dioxido - Google Patents
Procedimiento para la preparacion de las sales no toxicas del 6-metil-3,4-dihidro-1,2,3-oxatiazin-4-on-2,2-dioxidoInfo
- Publication number
- ES2000617A6 ES2000617A6 ES8601536A ES8601536A ES2000617A6 ES 2000617 A6 ES2000617 A6 ES 2000617A6 ES 8601536 A ES8601536 A ES 8601536A ES 8601536 A ES8601536 A ES 8601536A ES 2000617 A6 ES2000617 A6 ES 2000617A6
- Authority
- ES
- Spain
- Prior art keywords
- dihydro
- methyl
- dioxide
- oxatiazin
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 231100000252 nontoxic Toxicity 0.000 title abstract 3
- 230000003000 nontoxic effect Effects 0.000 title abstract 3
- 150000003839 salts Chemical class 0.000 title abstract 3
- YGCFIWIQZPHFLU-UHFFFAOYSA-N acesulfame Chemical class CC1=CC(=O)NS(=O)(=O)O1 YGCFIWIQZPHFLU-UHFFFAOYSA-N 0.000 title 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 2
- XLYOFNOQVPJJNP-PWCQTSIFSA-N Tritiated water Chemical compound [3H]O[3H] XLYOFNOQVPJJNP-PWCQTSIFSA-N 0.000 abstract 2
- 239000012074 organic phase Substances 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 235000009508 confectionery Nutrition 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 229910001867 inorganic solvent Inorganic materials 0.000 abstract 1
- 239000003049 inorganic solvent Substances 0.000 abstract 1
- 238000006386 neutralization reaction Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D291/00—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms
- C07D291/02—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms not condensed with other rings
- C07D291/06—Six-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Seasonings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
LAS SALES NO TOXICAS DEL 6-METIL-3,4-DIHIDRO-1,2,3-OXATIAZIN-4-ON-2,2-DIOXIDO SE PREPARAN MEDIANTE CIERRE DE ANILLO DE ACETO-ACETAMIDO-N-ACIDO SULFONICO O DE SUS SALES CON UNA CANTIDAD DE SO3 POR LO MENOS APROXIMADAMENTE EQUIMOLAR EN PRESENCIA DE UN DISOLVENTE ORGANICO INERTE NO MISCIBLE CON AGUA, ASI COMO EVENTUALMENTE TAMBIEN DE UN DISOLVENTE INORGANICO INERTE; HIDROLISIS DEL 6-METIL-3,4-DIHIDRO-1,2,3-OXATIAZIN-4-ON-2,2-DIOXIDO RESULTANTE COMO ADUCTO CON SO3 DESPUES DE LA REACCION DE CIRRE DE ANILLO, EN EL CASO DE EMPLEARSE UNA CANTIDAD DE SO3 MAYOR QUE LA EQUIMOLAR; PURIFICACION DE LA FASE ORGANICA (SEPARADA) MEDIANTE EXTRACCION CON UN PEQUEÑO VOLUMEN DE AGUA O DE ACIDO SULFURICO ACUOSO DILUIDO, PREFERIBLEMENTE SOLO CON AGUA, Y OBTENCION DE LAS SALES NO TOXICAS DEL 6-METIL-3,4-DIHIDRO-1,2,3-OXATIAZIN-4-ON-2,2-DIOXIDO A PARTIR DE LA FASE ORGANICA, ASI PURIFICADA, MEDIANTE NEUTRALIZACION CON BASES. LAS MENCIONADAS SALES RESULTANTES EN ESTE CASO EN FORMA EXTRAORDINARIAMENTE PURA; ESTAS SONVALIOSAS SUSTANCIAS EDULCORANTES SINTETICAS. LA SAL POTASICA ES CONOCIDA COMO ACESULFAM (K).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19853531358 DE3531358A1 (de) | 1985-09-03 | 1985-09-03 | Verfahren zur herstellung der nicht-toxischen salze des 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-on-2,2-dioxids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2000617A6 true ES2000617A6 (es) | 1988-03-01 |
Family
ID=6279975
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8601536A Expired ES2000617A6 (es) | 1985-09-03 | 1986-09-01 | Procedimiento para la preparacion de las sales no toxicas del 6-metil-3,4-dihidro-1,2,3-oxatiazin-4-on-2,2-dioxido |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4804755A (es) |
| EP (1) | EP0218076B1 (es) |
| JP (1) | JPS6256481A (es) |
| KR (1) | KR940008749B1 (es) |
| CN (1) | CN1008736B (es) |
| AR (1) | AR248016A1 (es) |
| AT (1) | ATE49201T1 (es) |
| AU (1) | AU587855B2 (es) |
| BR (1) | BR8604201A (es) |
| CA (1) | CA1283913C (es) |
| CS (1) | CS262439B2 (es) |
| DD (1) | DD249272A5 (es) |
| DE (2) | DE3531358A1 (es) |
| DK (1) | DK168045B1 (es) |
| ES (1) | ES2000617A6 (es) |
| FI (1) | FI83077C (es) |
| HU (1) | HU200758B (es) |
| IE (1) | IE59132B1 (es) |
| IL (1) | IL79894A (es) |
| MX (1) | MX173526B (es) |
| NO (1) | NO163856C (es) |
| SU (1) | SU1582988A3 (es) |
| ZA (1) | ZA866647B (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3429039A1 (de) * | 1984-08-07 | 1986-02-20 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung von6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-on-2,2-dioxid und dessen nichttoxischen salzen |
| DE3531359A1 (de) * | 1985-09-03 | 1987-03-12 | Hoechst Ag | Verfahren zur herstellung von 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-on-2,2-dioxid sowie zu dessen reinigung |
| TW223067B (es) * | 1992-03-17 | 1994-05-01 | Hoechst Ag | |
| DE10253773B3 (de) * | 2002-11-19 | 2004-06-24 | Nutrinova Nutrition Specialties & Food Ingredients Gmbh | Verwendung von Acesulfamsäure zur pH-Wert-Absenkung |
| JP2005263779A (ja) * | 2004-02-17 | 2005-09-29 | Daicel Chem Ind Ltd | ３，４−ジヒドロ−１，２，３−オキサチアジン−４−オン−２，２−ジオキサイド化合物又はその塩の製造法 |
| JP2008037777A (ja) * | 2006-08-03 | 2008-02-21 | Daicel Chem Ind Ltd | ３，４−ジヒドロ−１，２，３−オキサチアジン−４−オン−２，２−ジオキサイド化合物のカリウム塩の製造方法 |
| JP2008037778A (ja) | 2006-08-03 | 2008-02-21 | Daicel Chem Ind Ltd | ３，４−ジヒドロ−１，２，３−オキサチアジン−４−オン−２，２−ジオキサイド化合物又はその塩の製造法 |
| US9024016B2 (en) | 2012-06-08 | 2015-05-05 | Nutrinova Nutrition Specialists & Food Ingredients GmbH | Process for producing acesulfame potassium |
| LT3319949T (lt) | 2016-09-21 | 2020-11-10 | Celanese International Corporation | Kalio acesulfamo kompozicijos ir jų gamybos būdas |
| WO2018057387A1 (en) | 2016-09-21 | 2018-03-29 | Celanese International Corporation | Acesulfame potassium compositions and processes for producing same |
| HRP20201619T4 (hr) * | 2016-09-21 | 2025-03-28 | Celanese International Corporation | Pripravci kalijevog acesulfama i postupci za njegovu proizvodnju |
| JP6818896B2 (ja) * | 2016-09-21 | 2021-01-27 | セラニーズ・インターナショナル・コーポレーション | アセスルファムカリウム組成物及びその製造方法 |
| CN109369572A (zh) * | 2018-10-25 | 2019-02-22 | 苏州浩波科技股份有限公司 | 一种安赛蜜的纯化工艺 |
| CN109593071A (zh) * | 2018-12-10 | 2019-04-09 | 安徽金禾实业股份有限公司 | 一种连续可控的安赛蜜重结晶离心装置及方法 |
| US20230382877A1 (en) * | 2020-09-21 | 2023-11-30 | Anhui Jinhe Industrial Co., Ltd. | Method for refining acesulfame potassium |
| WO2023123405A1 (zh) * | 2021-12-31 | 2023-07-06 | 安徽金禾实业股份有限公司 | 一种对含有乙酰磺胺酸的水解反应产物的处理方法和装置 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2327804C3 (de) * | 1973-06-01 | 1980-08-14 | Hoechst Ag, 6000 Frankfurt | Verfahren zur Herstellung von 3,4-Dihydro-l,23-oxathiazin-4-onen |
| DE2434548C2 (de) * | 1974-07-18 | 1982-11-18 | Hoechst Ag, 6000 Frankfurt | Verfahren zur Herstellung von Fluoridarmem 6-Methyl-3,4-dihydro-1,2,3-oxathiazin-4-on-2,2-dioxid-kalium |
| DE2453063A1 (de) * | 1974-11-08 | 1976-05-13 | Hoechst Ag | Verfahren zur herstellung von acetoacetamid-n-sulfofluorid |
| DE3410439A1 (de) * | 1984-03-22 | 1985-09-26 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung von 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-on-2,2-dioxid und dessen nichttoxischen salzen sowie der dabei als zwischenprodukt(e) auftretenden acetoacetamind-n-sulfonsaeure(salze) |
| DE3410440A1 (de) * | 1984-03-22 | 1985-09-26 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung von 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-on-2,2-dioxid und dessen nichttoxischen salzen |
| DE3531359A1 (de) * | 1985-09-03 | 1987-03-12 | Hoechst Ag | Verfahren zur herstellung von 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-on-2,2-dioxid sowie zu dessen reinigung |
-
1985
- 1985-09-03 DE DE19853531358 patent/DE3531358A1/de not_active Withdrawn
-
1986
- 1986-08-27 DE DE8686111841T patent/DE3667972D1/de not_active Expired - Lifetime
- 1986-08-27 EP EP86111841A patent/EP0218076B1/de not_active Expired - Lifetime
- 1986-08-27 AT AT86111841T patent/ATE49201T1/de not_active IP Right Cessation
- 1986-08-29 CA CA000517246A patent/CA1283913C/en not_active Expired - Lifetime
- 1986-08-29 US US06/902,427 patent/US4804755A/en not_active Expired - Lifetime
- 1986-09-01 IL IL79894A patent/IL79894A/xx not_active IP Right Cessation
- 1986-09-01 FI FI863523A patent/FI83077C/fi not_active IP Right Cessation
- 1986-09-01 CS CS866323A patent/CS262439B2/cs not_active IP Right Cessation
- 1986-09-01 SU SU864028038A patent/SU1582988A3/ru active
- 1986-09-01 ES ES8601536A patent/ES2000617A6/es not_active Expired
- 1986-09-01 HU HU863764A patent/HU200758B/hu not_active IP Right Cessation
- 1986-09-01 DD DD86294054A patent/DD249272A5/de not_active IP Right Cessation
- 1986-09-02 NO NO863504A patent/NO163856C/no not_active IP Right Cessation
- 1986-09-02 DK DK418186A patent/DK168045B1/da not_active IP Right Cessation
- 1986-09-02 ZA ZA866647A patent/ZA866647B/xx unknown
- 1986-09-02 AU AU62173/86A patent/AU587855B2/en not_active Expired
- 1986-09-02 BR BR8604201A patent/BR8604201A/pt not_active IP Right Cessation
- 1986-09-02 CN CN86105877A patent/CN1008736B/zh not_active Expired
- 1986-09-02 IE IE234486A patent/IE59132B1/en not_active IP Right Cessation
- 1986-09-02 JP JP61205245A patent/JPS6256481A/ja active Granted
- 1986-09-03 KR KR1019860007363A patent/KR940008749B1/ko not_active Expired - Lifetime
- 1986-09-03 MX MX003636A patent/MX173526B/es unknown
- 1986-09-11 AR AR86305109A patent/AR248016A1/es active
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| SA6 | Expiration date (snapshot 920101) |
Free format text: 2006-09-01 |
|
| FD1A | Patent lapsed |
Effective date: 20060902 |