ES2006417T3 - Sintesis de utilizacion de polianhidridos de alto peso molecular. - Google Patents

Sintesis de utilizacion de polianhidridos de alto peso molecular.

Info

Publication number
ES2006417T3
ES2006417T3 ES87110971T ES87110971T ES2006417T3 ES 2006417 T3 ES2006417 T3 ES 2006417T3 ES 87110971 T ES87110971 T ES 87110971T ES 87110971 T ES87110971 T ES 87110971T ES 2006417 T3 ES2006417 T3 ES 2006417T3
Authority
ES
Spain
Prior art keywords
molecular weight
high molecular
polyanhydrides
prepolymers
synthesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87110971T
Other languages
English (en)
Other versions
ES2006417A4 (es
Inventor
Robert S Langer
Abraham J Domb
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
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Massachusetts Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Institute of Technology filed Critical Massachusetts Institute of Technology
Publication of ES2006417A4 publication Critical patent/ES2006417A4/es
Application granted granted Critical
Publication of ES2006417T3 publication Critical patent/ES2006417T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G67/00Macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing oxygen or oxygen and carbon, not provided for in groups C08G2/00 - C08G65/00
    • C08G67/04Polyanhydrides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Polyethers (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polyamides (AREA)

Abstract

LOS POLIANHIDRIDOS DE ALTO PESO MOLECULAR, DEFINIDOS COMO POLIANHIDRIDOS QUE TIENE UN PESO MOLECULAR MEDIO MAYOR DE 20.000 O UNA VISCOSIDAD INTRINSECA MAYOR DE 0,3 DL/G EN UN SOLVENTE ORGANICO A TEMPERATURA AMBIENTE, SE FORMAN MEDIANTE UNA POLICONDENSACION POR FUSION DE PREPOLIMEROS AISLADOS MUY PUROS BAJO CONDICIONES DE REACCION OPTIMIZADAS, EN PARTICULAR DE TIEMPO Y TEMPERATURA, CON LA RETIRADA DEL PRODUCTO DE CONDENSACION. SE PUEDEN OBTENER PESOS MOLECULARES MAS ALTOS SI SE INCLUYE UN CATALIZADOR CON LOS PREPOLIMEROS EN LA POLIMERIZACION POR FUSION. SE PUEDEN UTILIZAR LOS CATALIZADORES EMPLEADOS PARA LA TRANSESTERIFICACION, LA POLIMERIZACION DE ABERTURA DE ANILLO Y POLIMERIZACIONES RELACIONADAS. LOS POLIANHIDRIDOS DE ALTO PESO MOLECULAR TIENEN UNAS PROPIEDADES FISICO-MECANICAS MEJORADAS Y SON ESPECIALMENTE ADECUADOS PARA APLICACIONES BIOMEDICAS, EN PARTICULAR PARA LOS DISPOSITIVOS DE LIBERACION CONTROLADA PARA EL SUMINISTRO DE MEDICAMENTOS.
ES87110971T 1986-08-01 1987-07-29 Sintesis de utilizacion de polianhidridos de alto peso molecular. Expired - Lifetime ES2006417T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/892,809 US4757128A (en) 1986-08-01 1986-08-01 High molecular weight polyanhydride and preparation thereof

Publications (2)

Publication Number Publication Date
ES2006417A4 ES2006417A4 (es) 1989-05-01
ES2006417T3 true ES2006417T3 (es) 1997-07-01

Family

ID=25400529

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87110971T Expired - Lifetime ES2006417T3 (es) 1986-08-01 1987-07-29 Sintesis de utilizacion de polianhidridos de alto peso molecular.

Country Status (11)

Country Link
US (1) US4757128A (es)
EP (1) EP0260415B1 (es)
JP (1) JP2700646B2 (es)
KR (1) KR880002904A (es)
AT (1) ATE145657T1 (es)
CA (1) CA1274339A (es)
DE (2) DE260415T1 (es)
ES (1) ES2006417T3 (es)
GR (2) GR880300163T1 (es)
LU (1) LU90462I2 (es)
NL (1) NL990036I2 (es)

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DE3751964D1 (de) 1997-01-09
EP0260415A3 (en) 1988-05-18
DE260415T1 (de) 1989-02-16
CA1274339A (en) 1990-09-18
KR880002904A (ko) 1988-05-12
JP2700646B2 (ja) 1998-01-21
NL990036I1 (nl) 1999-12-01
DE3751964T2 (de) 1997-06-05
EP0260415B1 (en) 1996-11-27
LU90462I2 (fr) 2000-01-03
EP0260415A2 (en) 1988-03-23
NL990036I2 (nl) 2001-01-02
JPS63258924A (ja) 1988-10-26
GR880300163T1 (en) 1989-01-31
US4757128A (en) 1988-07-12
ATE145657T1 (de) 1996-12-15
ES2006417A4 (es) 1989-05-01

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