ES2008631A6 - Un procedimiento para la produccion de derivados de tiofen -3n4-carboxamida. - Google Patents
Un procedimiento para la produccion de derivados de tiofen -3n4-carboxamida.Info
- Publication number
- ES2008631A6 ES2008631A6 ES8803045A ES8803045A ES2008631A6 ES 2008631 A6 ES2008631 A6 ES 2008631A6 ES 8803045 A ES8803045 A ES 8803045A ES 8803045 A ES8803045 A ES 8803045A ES 2008631 A6 ES2008631 A6 ES 2008631A6
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- phenyl
- substd
- alkenyloxy
- opt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- YNSCKPCDFIDINW-UHFFFAOYSA-N 3-[[2-[[1-[2-(dimethylamino)acetyl]-6-methoxy-4,4-dimethyl-2,3-dihydroquinolin-7-yl]amino]-7h-pyrrolo[2,3-d]pyrimidin-4-yl]amino]thiophene-2-carboxamide Chemical compound COC1=CC(C(CCN2C(=O)CN(C)C)(C)C)=C2C=C1NC(N=C1NC=CC1=1)=NC=1NC=1C=CSC=1C(N)=O YNSCKPCDFIDINW-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- -1 phenylthio, phenyl sulphinyl Chemical group 0.000 abstract 3
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 208000028017 Psychotic disease Diseases 0.000 abstract 1
- 206010047700 Vomiting Diseases 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000004644 alkyl sulfinyl group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical compound O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000008673 vomiting Effects 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
UN PROCEDIMIENTO PARA LA PRODUCCION DE DERIVADOS DE TIOFEN-3/4-CARBOXAMIDA DE FORMULA (I), DONDE R1, R2 Y R3 SON INDEPENDIENTEMENTE HIDROGENO, HIDROXI, HALO, NITRO, AMINO, ACILAMINO, C2-5, ALQUILO C1-4, -CHO, -CH2OH, -CH2O-ALQUILO C1-4, -COOH, -CO-ALQUILO C1-3, -CH(OH)-ALQUILO C1-3, ALCOXI C1-4, ALQUENILOXI C2-4, ALQUILTIO C1-4, ALQUILSULFINILO C1-4, AQUILSULFONILO C1-4, HETEROCICLIO N-SUSTITUIDO, FENILO, FENILTIO, FENILSULFINILO, FENILSULFONILO O FENILSULFONAMIDO OPCIONALMENTE SUSTITUIDOS; O R1 Y R2 UNIDOS FORMAN UN PUENTE DE ALQUILENO C3-5; CON LA CONDICION DE QUE UNO DE R2 Y R3 ES ALCOXI C1-4 O ALQUENILOXI X2-4; Y X ES -(CH2)NN(R4)2, DONDE CADA GRUPO R4 ES INDEPENDIENTEMENTE ALQUILO C1-4, ALQUENILO C2-4 O C6H5CH2- OPCIONALMENTE SUSTITUIDO, Y N ES 1, 2 O 3; QUE COMPRENDE LA REACCION ENTRE UN COMPUESTO (II), DONDE Z ES HALO, -OH, U -OR (SIENDO R UN GRUPO SALIENTE) Y UNA AMINA X-N
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES8803045A ES2008631A6 (es) | 1988-10-06 | 1988-10-06 | Un procedimiento para la produccion de derivados de tiofen -3n4-carboxamida. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES8803045A ES2008631A6 (es) | 1988-10-06 | 1988-10-06 | Un procedimiento para la produccion de derivados de tiofen -3n4-carboxamida. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2008631A6 true ES2008631A6 (es) | 1989-07-16 |
Family
ID=8258374
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8803045A Expired ES2008631A6 (es) | 1988-10-06 | 1988-10-06 | Un procedimiento para la produccion de derivados de tiofen -3n4-carboxamida. |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES2008631A6 (es) |
-
1988
- 1988-10-06 ES ES8803045A patent/ES2008631A6/es not_active Expired
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| SA6 | Expiration date (snapshot 920101) |
Free format text: 2008-10-06 |
|
| FD1A | Patent lapsed |
Effective date: 20000201 |