ES2009147A6 - Nuevo proceso para la preparacion de polimorfos de famotidina - Google Patents

Nuevo proceso para la preparacion de polimorfos de famotidina

Info

Publication number: ES2009147A6
Authority: ES; Spain
Prior art keywords: famotidine; prepd; chlorinated hydrocarbon; bio; activity
Prior art date: 1987-06-22
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES8702020A

Other languages

English (en)

Spanish (es)

Inventor

Rodes Montserrat Ballester

Nicolau Francisco Eugen Palomo

Coll Antonio Luis Palomo

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Centro Marga Para la Investigacion SA

Original Assignee

Centro Marga Para la Investigacion SA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-06-22

Filing date

1987-06-22

Publication date

1989-09-01

1987-06-22 Application filed by Centro Marga Para la Investigacion SA filed Critical Centro Marga Para la Investigacion SA

1987-06-22 Priority to ES8702020A priority Critical patent/ES2009147A6/es

1988-05-10 Priority to NO882037A priority patent/NO882037L/no

1988-05-10 Priority to IL86330A priority patent/IL86330A0/xx

1988-05-11 Priority to IS3342A priority patent/IS3342A7/is

1988-05-18 Priority to FI882329A priority patent/FI882329A7/fi

1988-05-23 Priority to US07/197,329 priority patent/US5021582A/en

1988-05-25 Priority to CN88103190A priority patent/CN1030077A/zh

1988-05-31 Priority to JP63134279A priority patent/JPH01100162A/ja

1988-06-01 Priority to DE8888500054T priority patent/DE3865899D1/de

1988-06-01 Priority to EP88500054A priority patent/EP0297019B1/en

1988-06-01 Priority to AT88500054T priority patent/ATE69052T1/de

1988-06-14 Priority to AU17672/88A priority patent/AU1767288A/en

1988-06-20 Priority to KR1019880007442A priority patent/KR920000308B1/ko

1988-06-21 Priority to CA000569954A priority patent/CA1322760C/en

1988-06-21 Priority to ZA884408A priority patent/ZA884408B/xx

1988-06-22 Priority to DK342988A priority patent/DK342988A/da

1989-09-01 Publication of ES2009147A6 publication Critical patent/ES2009147A6/es

Status Expired legal-status Critical Current

Links

XUFQPHANEAPEMJ-UHFFFAOYSA-N famotidine Chemical compound NC(N)=NC1=NC(CSCCC(N)=NS(N)(=O)=O)=CS1 XUFQPHANEAPEMJ-UHFFFAOYSA-N 0.000 title abstract 3
229960001596 famotidine Drugs 0.000 title abstract 3
150000008280 chlorinated hydrocarbons Chemical class 0.000 title abstract 2
239000002904 solvent Substances 0.000 title 1
239000000126 substance Substances 0.000 title 1
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 abstract 3
HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 2
YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 abstract 2
239000013078 crystal Substances 0.000 abstract 2
VZGDMQKNWNREIO-UHFFFAOYSA-N tetrachloromethane Chemical compound ClC(Cl)(Cl)Cl VZGDMQKNWNREIO-UHFFFAOYSA-N 0.000 abstract 2
XQFGVGNRDPFKFJ-UHFFFAOYSA-N 1,2,3,5,6,7-hexahydropyrrolo[1,2-b]pyridazine Chemical compound N1CCC=C2CCCN21 XQFGVGNRDPFKFJ-UHFFFAOYSA-N 0.000 abstract 1
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
CPELXLSAUQHCOX-UHFFFAOYSA-N Hydrogen bromide Chemical compound Br CPELXLSAUQHCOX-UHFFFAOYSA-N 0.000 abstract 1
229910002651 NO3 Inorganic materials 0.000 abstract 1
NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 abstract 1
229910019142 PO4 Inorganic materials 0.000 abstract 1
QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
238000002441 X-ray diffraction Methods 0.000 abstract 1
238000001816 cooling Methods 0.000 abstract 1
ZJULYDCRWUEPTK-UHFFFAOYSA-N dichloromethyl Chemical compound Cl[CH]Cl ZJULYDCRWUEPTK-UHFFFAOYSA-N 0.000 abstract 1
238000007865 diluting Methods 0.000 abstract 1
230000001747 exhibiting effect Effects 0.000 abstract 1
238000001914 filtration Methods 0.000 abstract 1
238000010899 nucleation Methods 0.000 abstract 1
150000007530 organic bases Chemical group 0.000 abstract 1
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
239000010452 phosphate Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229910021653 sulphate ion Inorganic materials 0.000 abstract 1
JABYJIQOLGWMQW-UHFFFAOYSA-N undec-4-ene Chemical compound CCCCCCC=CCCC JABYJIQOLGWMQW-UHFFFAOYSA-N 0.000 abstract 1

Landscapes

Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ES8702020A 1987-06-22 1987-06-22 Nuevo proceso para la preparacion de polimorfos de famotidina Expired ES2009147A6 (es)

Priority Applications (16)

Application Number	Priority Date	Filing Date	Title
ES8702020A ES2009147A6 (es)	1987-06-22	1987-06-22	Nuevo proceso para la preparacion de polimorfos de famotidina
NO882037A NO882037L (no)	1987-06-22	1988-05-10	Famotidin, polymerte former og fremstilling derav.
IL86330A IL86330A0 (en)	1987-06-22	1988-05-10	Famotidine polymorphic forms and their preparation
IS3342A IS3342A7 (is)	1987-06-22	1988-05-11	Famotidine (N-sulfamoyl-3-)2-guanidionthiazol-4-yl) methylthioprooionamidine:) og aðferð til framleiðslu þess.
FI882329A FI882329A7 (fi)	1987-06-22	1988-05-18	Polymorfiska former av famotidin och foerfarande foer framstaellning daerav.
US07/197,329 US5021582A (en)	1987-06-22	1988-05-23	Famotidine polymorphic forms and their preparation process
CN88103190A CN1030077A (zh)	1987-06-22	1988-05-25	法莫丁啶多晶型物及其制备方法
JP63134279A JPH01100162A (ja)	1987-06-22	1988-05-31	ファモチジン多形型およびそれらの製造方法
DE8888500054T DE3865899D1 (de)	1987-06-22	1988-06-01	Polymorphe form des famotidins und ihr herstellungsverfahren.
EP88500054A EP0297019B1 (en)	1987-06-22	1988-06-01	Famotidine polymorphic form and preparation thereof
AT88500054T ATE69052T1 (de)	1987-06-22	1988-06-01	Polymorphe form des famotidins und ihr herstellungsverfahren.
AU17672/88A AU1767288A (en)	1987-06-22	1988-06-14	Famotidine polymorphic forms and their preparation process
KR1019880007442A KR920000308B1 (ko)	1987-06-22	1988-06-20	안정한 파모티딘결정형 폴리모르프 및 그 제조방법
CA000569954A CA1322760C (en)	1987-06-22	1988-06-21	Famotidine polymorphic forms and their preparation process
ZA884408A ZA884408B (en)	1987-06-22	1988-06-21	Famotidine polymorphic forms and their preparation process
DK342988A DK342988A (da)	1987-06-22	1988-06-22	Polymorfe famotidinformer og fremgangsmaader til fremstilling heraf

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ES8702020A ES2009147A6 (es)	1987-06-22	1987-06-22	Nuevo proceso para la preparacion de polimorfos de famotidina

Publications (1)

Publication Number	Publication Date
ES2009147A6 true ES2009147A6 (es)	1989-09-01

Family

ID=8251688

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES8702020A Expired ES2009147A6 (es)	1987-06-22	1987-06-22	Nuevo proceso para la preparacion de polimorfos de famotidina

Country Status (3)

Country	Link
ES (1)	ES2009147A6 (is)
IS (1)	IS3342A7 (is)
ZA (1)	ZA884408B (is)

1987
- 1987-06-22 ES ES8702020A patent/ES2009147A6/es not_active Expired
1988
- 1988-05-11 IS IS3342A patent/IS3342A7/is unknown
- 1988-06-21 ZA ZA884408A patent/ZA884408B/xx unknown

Also Published As

Publication number	Publication date
IS3342A7 (is)	1988-12-23
ZA884408B (en)	1989-03-29

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Legal Events

Date	Code	Title	Description
2000-01-16	FD1A	Patent lapsed	Effective date: 19991209