ES2009917A6 - Composicion opacificante inyectable para examenes con rayos x, que contiene liposomas con elevada capacidad de encapsulado. - Google Patents

Composicion opacificante inyectable para examenes con rayos x, que contiene liposomas con elevada capacidad de encapsulado.

Info

Publication number
ES2009917A6
ES2009917A6 ES8801604A ES8801604A ES2009917A6 ES 2009917 A6 ES2009917 A6 ES 2009917A6 ES 8801604 A ES8801604 A ES 8801604A ES 8801604 A ES8801604 A ES 8801604A ES 2009917 A6 ES2009917 A6 ES 2009917A6
Authority
ES
Spain
Prior art keywords
opacifying
injectable composition
medium
containing liposomes
ray
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8801604A
Other languages
English (en)
Inventor
Michel Schneider
Herve Tournier
Bernard Lamy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bracco SpA
Original Assignee
Bracco SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4223355&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2009917(A6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bracco SpA filed Critical Bracco SpA
Publication of ES2009917A6 publication Critical patent/ES2009917A6/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0461—Dispersions, colloids, emulsions or suspensions
    • A61K49/0466—Liposomes, lipoprotein vesicles, e.g. HDL or LDL lipoproteins, phospholipidic or polymeric micelles

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

COMPOSICION OPACIFICANTE INYECTABLE PARA EXAMENES CON RAYOS X, QUE CONTIENE LIPOSOMAS CON ELEVADA CAPACIDAD DE ENCAPSULADO, ACUOSA INYECTABLE, DESTINADA A OPACIFICAR ORGANOS PARA EXAMEN CON RAYOS X, CONSTITUIDA POR UNA SUSPENSION, EN UN MEDIO ACUOSO FISIOLOGICAMENTE TOLERABLE, DE VESICULAS LIPOSOMICAS CON MEMBRANA LIPIDICA QUE CONTIENE, ENCAPSULADO EN ESTAS VESICULAS, AL MENOS UN COMPUESTO ORGANICO YODADO OPACO A LOS RAYOS X EN SOLUCION ACUOSA, CARACTERIZADA PORQUE LAS VESICULAS DE LOS LIPOSOMAS TIENEN UN TAMAÑO MEDIO COMPRENDIDO ENTRE 0,15 Y 3 MICRAS Y PORQUE LA RELACION DEL PESO DEL YODO ENCAPSULADO EN LAS VESICULAS LIPOSOMICAS AL PESO DE LOS LIPIDOS DE LA CITADA MEMBRANA ES DE 1,5 A 6 G/G.
ES8801604A 1987-05-22 1988-05-20 Composicion opacificante inyectable para examenes con rayos x, que contiene liposomas con elevada capacidad de encapsulado. Expired ES2009917A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1991/87A CH672733A5 (es) 1987-05-22 1987-05-22

Publications (1)

Publication Number Publication Date
ES2009917A6 true ES2009917A6 (es) 1989-10-16

Family

ID=4223355

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8801604A Expired ES2009917A6 (es) 1987-05-22 1988-05-20 Composicion opacificante inyectable para examenes con rayos x, que contiene liposomas con elevada capacidad de encapsulado.

Country Status (13)

Country Link
US (3) US5312615A (es)
EP (1) EP0314764B2 (es)
JP (1) JP2619037B2 (es)
AT (1) ATE80294T1 (es)
AU (1) AU612371B2 (es)
CA (1) CA1303978C (es)
CH (1) CH672733A5 (es)
DE (1) DE3874485T3 (es)
ES (1) ES2009917A6 (es)
IL (1) IL86409A (es)
MX (1) MX9203271A (es)
WO (1) WO1988009165A1 (es)
ZA (1) ZA883449B (es)

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US6989141B2 (en) * 1990-05-18 2006-01-24 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US6613306B1 (en) * 1990-04-02 2003-09-02 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US5578292A (en) 1991-11-20 1996-11-26 Bracco International B.V. Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof
US20040208826A1 (en) * 1990-04-02 2004-10-21 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
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US20030194376A1 (en) * 1990-05-18 2003-10-16 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
IS1685B (is) * 1990-12-11 1998-02-24 Bracco International B.V. Aðferð við að búa til fitukúlur (liposomes) sem eru gæddar auknum hæfileika til að draga í sig og halda í sér aðskotaefnum
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JPH08505312A (ja) * 1992-10-16 1996-06-11 ザックセ，アンドレアス 液状分散系を製造する方法及び装置
EP0699068B1 (en) * 1993-05-21 2001-12-19 The Liposome Company, Inc. Reduction of liposome-induced adverse physiological reactions
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US7083572B2 (en) 1993-11-30 2006-08-01 Bristol-Myers Squibb Medical Imaging, Inc. Therapeutic delivery systems
CN1068229C (zh) * 1993-12-15 2001-07-11 勃勒柯研究有限公司 超声对比介质、含该介质的对比剂及方法
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US6414139B1 (en) 1996-09-03 2002-07-02 Imarx Therapeutics, Inc. Silicon amphiphilic compounds and the use thereof
US5846517A (en) 1996-09-11 1998-12-08 Imarx Pharmaceutical Corp. Methods for diagnostic imaging using a renal contrast agent and a vasodilator
US6090800A (en) 1997-05-06 2000-07-18 Imarx Pharmaceutical Corp. Lipid soluble steroid prodrugs
US6120751A (en) 1997-03-21 2000-09-19 Imarx Pharmaceutical Corp. Charged lipids and uses for the same
US6537246B1 (en) 1997-06-18 2003-03-25 Imarx Therapeutics, Inc. Oxygen delivery agents and uses for the same
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US6416740B1 (en) 1997-05-13 2002-07-09 Bristol-Myers Squibb Medical Imaging, Inc. Acoustically active drug delivery systems
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JP4109780B2 (ja) 1998-03-06 2008-07-02 株式会社東海理化電機製作所 ギヤ機構及びウエビング巻取装置
WO1999049849A1 (en) * 1998-03-31 1999-10-07 Yissum Research Development Company Of The Hebrew University Of Jerusalem Liposomal bupivacaine compositions and methods of preparation
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JP3980777B2 (ja) 1998-11-02 2007-09-26 株式会社東海理化電機製作所 ウエビング巻取装置
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JP4654590B2 (ja) * 2004-03-31 2011-03-23 コニカミノルタエムジー株式会社 Ｘ線ｃｔ用造影組成物およびその製造方法
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JP5176320B2 (ja) * 2004-08-11 2013-04-03 コニカミノルタエムジー株式会社 リポソーム含有製剤の製造方法
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JP2011506325A (ja) 2007-12-05 2011-03-03 マーバル バイオサイエンシーズ インコーポレイテッド ナノスケールのコントラスト剤及びその使用方法
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Also Published As

Publication number Publication date
DE3874485T2 (de) 1993-03-11
EP0314764B2 (en) 2000-02-02
AU1805488A (en) 1988-12-21
MX9203271A (es) 1992-07-01
IL86409A0 (en) 1988-11-15
EP0314764A1 (en) 1989-05-10
IL86409A (en) 1991-12-12
CA1303978C (en) 1992-06-23
DE3874485T3 (de) 2000-09-14
JP2619037B2 (ja) 1997-06-11
ATE80294T1 (de) 1992-09-15
US5312615A (en) 1994-05-17
US5626832A (en) 1997-05-06
EP0314764B1 (en) 1992-09-09
WO1988009165A1 (en) 1988-12-01
CH672733A5 (es) 1989-12-29
AU612371B2 (en) 1991-07-11
US5445810A (en) 1995-08-29
ZA883449B (en) 1988-11-16
JPH02500192A (ja) 1990-01-25
DE3874485D1 (de) 1992-10-15

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Effective date: 20040521