ES2013184A6 - Un procemiento para producir un activador de plasminogeno de tipo tejido (t-pa) mejorado. - Google Patents

Un procemiento para producir un activador de plasminogeno de tipo tejido (t-pa) mejorado.

Info

Publication number
ES2013184A6
ES2013184A6 ES8901500A ES8901500A ES2013184A6 ES 2013184 A6 ES2013184 A6 ES 2013184A6 ES 8901500 A ES8901500 A ES 8901500A ES 8901500 A ES8901500 A ES 8901500A ES 2013184 A6 ES2013184 A6 ES 2013184A6
Authority
ES
Spain
Prior art keywords
procedure
producing
plasminogen activator
type plasminogen
improved
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES8901500A
Other languages
English (en)
Inventor
Yasushi Kamauchi
Toshiyuki Takemoto
Makoto Takayama
Masami Yokota
Masao Kato
Kimio Katsuta
Hiroshi Gushima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Priority to ES8901500A priority Critical patent/ES2013184A6/es
Publication of ES2013184A6 publication Critical patent/ES2013184A6/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

UN PROCEDIMIENTO PARA PRODUCIR UN ACTIVADOR DE PLASMINOGENO DE TIPO TEJIDO (T-PA) MEJORADO. COMPRENDE: (A) OBTENCION DEL GEN CODIFICANTE DE LA MOLECULA DE T-PA MEJORADO POR HIBRIDACION DEL GEN T-PA CON UNA SONDA OLIGONUCLEOTIDICA; (B) INSERTAR EL GEN OBTENIDO EN UN VECTOR DE EXPRESION; (C) TRANSFECTAR EL VECTOR DE EXPRESION EN UNA CELULA HUESPED; (D) RECUPERAR EL T-PA MEJORADO PRODUCIDO EN LA ETAPA ANTERIOR. APLICACION EN EL TRATAMIENTO DE LAS ENFERMEDADES DE CARACTER TROMBOTICO.
ES8901500A 1989-04-28 1989-04-28 Un procemiento para producir un activador de plasminogeno de tipo tejido (t-pa) mejorado. Expired - Fee Related ES2013184A6 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES8901500A ES2013184A6 (es) 1989-04-28 1989-04-28 Un procemiento para producir un activador de plasminogeno de tipo tejido (t-pa) mejorado.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES8901500A ES2013184A6 (es) 1989-04-28 1989-04-28 Un procemiento para producir un activador de plasminogeno de tipo tejido (t-pa) mejorado.

Publications (1)

Publication Number Publication Date
ES2013184A6 true ES2013184A6 (es) 1990-04-16

Family

ID=8261744

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8901500A Expired - Fee Related ES2013184A6 (es) 1989-04-28 1989-04-28 Un procemiento para producir un activador de plasminogeno de tipo tejido (t-pa) mejorado.

Country Status (1)

Country Link
ES (1) ES2013184A6 (es)

Similar Documents

Publication Publication Date Title
HUT46739A (en) Human manganese-superoxid-dismutale and process for its production
GR3021278T3 (en) Method of site-specific alteration of rna and production of encoded polypeptides
JPS56154999A (en) Synthesis of selective aged protein or polypeptide in bacteria matrix
MY101958A (en) Methods for producing human t-pa and expression vectors therefor.
ES8501629A1 (es) Procedimiento para producir t-p-a humano activador de plasminogeno.
ES8205263A1 (es) Un procedimiento para la produccion de una proteina activadora del piasminogeno.
HUT46065A (en) Process for producing new human tnf polypeptide mutants and dna encoding them
AU3802595A (en) Tripeptidyl aminopeptidase
DE69333491D1 (en) Protease-resistente analoge des thrombomodulin
FI102617B1 (fi) Ihmisen plasminogeenin aminohappovarianttia koodittava nukleiinihapposekvenssi, sitä sisältävä ekspressiovektori ja isäntäsolu sekä menetelmä plasminogeenin aminohappovariantin valmistamiseksi ja menetelmä kaksoiskompleksin muodostamiseksi fibrinolyyttisen entsyymin ja ......
HUT46360A (en) Process for producing proteins
ES2126262T3 (es) Cassette de expresion que comprende una region promotora salida del gen pho4 de schizosaccharomyces pombe.
EP0395653A4 (en) Synovial phospholipases
JPS6427477A (en) Dna and use thereof
IL154136A0 (en) Genes encoding branched-chain alpha-ketoacid dehydrogenase complex from streptomyces avermitilis
ES2013184A6 (es) Un procemiento para producir un activador de plasminogeno de tipo tejido (t-pa) mejorado.
EP0776972A4 (en) GENE CODING FOR IgG-Fc-BINDING PROTEIN
HUT63458A (en) Process for producing and using polypeptides participating in the biosynthesis of cobalamins and/or cobamides and dna sequences encoding them
AU1778988A (en) Novel fibrinolytic enzymes
ES8600400A1 (es) Un procedimiento para la produccion de histidina
CA2102043A1 (en) Mutant aox2 promoter, vector carrying same, transformant, and production of heterologous protein
AU3082795A (en) Hard and soft wheat thioredoxins h, homologous proteins, dna fragments coding for said proteins and methods for preparing same
DK0387646T3 (da) Achromobacter-protease I-gen og genprodukt deraf
AP9901463A0 (en) Streptomyces avermitilis gene directing the ratio of B2:B1 avermectins.
AR021450A1 (es) "molecula polinucleotidica que comprende una secuencia de nucleotidos de streptomices avermitil que dirige la relacion de avermectinas b2:b1, vector recombinante, celula huesped, procedimiento para obtener una cepa de s. avermitilis, celula de s. avermitilis que comprende dicha secuencia y procedimi

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20080429