ES2017805A6 - Production of preparation of aluminum salt of sucrose sulfuric acid ester - Google Patents

Production of preparation of aluminum salt of sucrose sulfuric acid ester

Info

Publication number
ES2017805A6
ES2017805A6 ES8701280A ES8701280A ES2017805A6 ES 2017805 A6 ES2017805 A6 ES 2017805A6 ES 8701280 A ES8701280 A ES 8701280A ES 8701280 A ES8701280 A ES 8701280A ES 2017805 A6 ES2017805 A6 ES 2017805A6
Authority
ES
Spain
Prior art keywords
sulfuric acid
acid ester
preparation
aluminum salt
polyethylene glycol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES8701280A
Other languages
Spanish (es)
Inventor
Yoshimitsu Iida
Minoru Machida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of ES2017805A6 publication Critical patent/ES2017805A6/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

PURPOSE:To obtain the titled preparation for treating peptic ulcer, having raised disintegration and dispersibility and high utility as drug, containing an aluminum salt of sucrose sulfuric acid ester and polyethylene glycol. CONSTITUTION:A preparation containing an aluminum salt of sucrose sulfuric acid ester and polyethylene glycol. Disintegration and dispersibility of aluminum salt of sucrose sulfuric acid ester (A for short) are raised by the use of polyethylene glycol and utility as drug is also elevated. Since A is insoluble in water, disintegration and dispersibility are raised to give effective bond to an ulcer site. The amount of the polyethylene glycol added is >=0.1 (W/W) based on A. When the preparation is orally administered, A is effectively bonded to the ulcer site.
ES8701280A 1986-04-30 1987-04-29 Production of preparation of aluminum salt of sucrose sulfuric acid ester Expired - Lifetime ES2017805A6 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9990186 1986-04-30

Publications (1)

Publication Number Publication Date
ES2017805A6 true ES2017805A6 (en) 1991-03-01

Family

ID=14259677

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8701280A Expired - Lifetime ES2017805A6 (en) 1986-04-30 1987-04-29 Production of preparation of aluminum salt of sucrose sulfuric acid ester

Country Status (9)

Country Link
JP (1) JP2542210B2 (en)
DE (1) DE3714159C2 (en)
DK (1) DK167735B1 (en)
ES (1) ES2017805A6 (en)
FI (1) FI89457C (en)
FR (1) FR2598084B1 (en)
IT (1) IT1208416B (en)
NO (1) NO174085C (en)
SE (1) SE503233C2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2112765A1 (en) * 1995-08-02 1998-04-01 Cantabria Ind Farmaceutica Sa PROCEDURE FOR OBTAINING RADIOLOGICAL CONTRAST FORMULATIONS, FOR GASTROINTESTINAL EXPLORATIONS FOR EXTEMPORARY AND DIRECT USE.

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2735559B2 (en) * 1988-03-02 1998-04-02 中外製薬株式会社 Suspension
CN1081921C (en) * 1994-04-26 2002-04-03 中外制药株式会社 Melt granulation preparation of sucralfate and production method thereof
WO1996023507A1 (en) * 1995-02-02 1996-08-08 Chugai Seiyaku Kabushiki Kaisha Sucralfate preparation
JP5870023B2 (en) * 2010-02-22 2016-02-24 第一三共株式会社 Oral sustained-release solid preparation
ES2706880T3 (en) 2010-02-22 2019-04-01 Daiichi Sankyo Co Ltd Sustained-release solid preparation for oral use
CA2883077C (en) 2012-09-03 2017-03-07 Daiichi Sankyo Company, Limited Hydromorphone hydrochloride-containing oral sustained-release pharmaceutical composition

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3430809A1 (en) * 1984-08-22 1986-03-06 Merck Patent Gmbh, 6100 Darmstadt SUCRALFAT SUSPENSION

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2112765A1 (en) * 1995-08-02 1998-04-01 Cantabria Ind Farmaceutica Sa PROCEDURE FOR OBTAINING RADIOLOGICAL CONTRAST FORMULATIONS, FOR GASTROINTESTINAL EXPLORATIONS FOR EXTEMPORARY AND DIRECT USE.

Also Published As

Publication number Publication date
FI89457C (en) 1993-10-11
DK167735B1 (en) 1993-12-13
DK218587A (en) 1987-10-31
FR2598084A1 (en) 1987-11-06
IT1208416B (en) 1989-06-12
NO871759D0 (en) 1987-04-28
NO174085B (en) 1993-12-06
SE8701787L (en) 1987-10-31
DK218587D0 (en) 1987-04-29
DE3714159C2 (en) 1996-09-19
SE8701787D0 (en) 1987-04-29
DE3714159A1 (en) 1987-11-05
FR2598084B1 (en) 1991-04-26
JPS63107933A (en) 1988-05-12
NO871759L (en) 1987-11-02
FI89457B (en) 1993-06-30
FI871852A0 (en) 1987-04-28
JP2542210B2 (en) 1996-10-09
SE503233C2 (en) 1996-04-22
NO174085C (en) 1994-03-16
IT8767365A0 (en) 1987-04-29
FI871852L (en) 1987-10-31

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20070430