ES2020974B3 - Medicamente conteniendo dipiridamol o mopidamol y o-acido acetilsalicilico o sus sales tratables fisiologicamente, procedimiento para su fabricacion y su utilizacion para combatir la formacion de trombos - Google Patents

Medicamente conteniendo dipiridamol o mopidamol y o-acido acetilsalicilico o sus sales tratables fisiologicamente, procedimiento para su fabricacion y su utilizacion para combatir la formacion de trombos

Info

Publication number: ES2020974B3
Authority: ES; Spain
Prior art keywords: mopidamol; physiologically; salts; thrombes; acetilsalicilico
Prior art date: 1986-08-13
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

ES87111104T

Other languages

English (en)

Inventor

Wolfgang Eisert

Peter Gruber

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Boehringer Ingelheim Pharma GmbH and Co KG

Original Assignee

Dr Karl Thomae GmbH

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-08-13

Filing date

1987-07-31

Publication date

1991-10-16

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6307286&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2020974(B3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1987-07-31 Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH

1991-10-16 Application granted granted Critical

1991-10-16 Publication of ES2020974B3 publication Critical patent/ES2020974B3/es

2007-07-31 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

230000015572 biosynthetic process Effects 0.000 title abstract 2
IZEKFCXSFNUWAM-UHFFFAOYSA-N dipyridamole Chemical compound C=12N=C(N(CCO)CCO)N=C(N3CCCCC3)C2=NC(N(CCO)CCO)=NC=1N1CCCCC1 IZEKFCXSFNUWAM-UHFFFAOYSA-N 0.000 title abstract 2
FOYWNSCCNCUEPU-UHFFFAOYSA-N mopidamol Chemical compound C12=NC(N(CCO)CCO)=NC=C2N=C(N(CCO)CCO)N=C1N1CCCCC1 FOYWNSCCNCUEPU-UHFFFAOYSA-N 0.000 title abstract 2
229950010718 mopidamol Drugs 0.000 title abstract 2
150000003839 salts Chemical class 0.000 title abstract 2
239000002253 acid Substances 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
238000000034 method Methods 0.000 title 1
BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 abstract 1
208000007536 Thrombosis Diseases 0.000 abstract 1
229960002768 dipyridamole Drugs 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Hematology (AREA)
Diabetes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

ES87111104T 1986-08-13 1987-07-31 Medicamente conteniendo dipiridamol o mopidamol y o-acido acetilsalicilico o sus sales tratables fisiologicamente, procedimiento para su fabricacion y su utilizacion para combatir la formacion de trombos Expired - Lifetime ES2020974B3 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19863627423 DE3627423A1 (de)	1986-08-13	1986-08-13	Arzneimittel enthaltend dipyridamol oder mopidamol und o-acetylsalicylsaeure bzw. deren physiologisch vertraegliche salze, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung der thrombusbildung

Publications (1)

Publication Number	Publication Date
ES2020974B3 true ES2020974B3 (es)	1991-10-16

Family

ID=6307286

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES87111104T Expired - Lifetime ES2020974B3 (es)	1986-08-13	1987-07-31	Medicamente conteniendo dipiridamol o mopidamol y o-acido acetilsalicilico o sus sales tratables fisiologicamente, procedimiento para su fabricacion y su utilizacion para combatir la formacion de trombos

Country Status (26)

Country	Link
US (1)	US6015577A (es)
EP (1)	EP0257344B1 (es)
JP (1)	JP2593879B2 (es)
KR (1)	KR950009098B1 (es)
AT (1)	ATE59961T1 (es)
AU (1)	AU603146B2 (es)
BR (1)	BR1100593A (es)
CA (1)	CA1302272C (es)
CL (1)	CL2004001252A1 (es)
DD (1)	DD263918A5 (es)
DE (3)	DE3627423A1 (es)
DK (1)	DK172236B1 (es)
ES (1)	ES2020974B3 (es)
FI (1)	FI873492A7 (es)
GR (1)	GR3001695T3 (es)
HK (1)	HK14494A (es)
HU (1)	HU202404B (es)
IE (1)	IE60862B1 (es)
IL (1)	IL83510A (es)
NL (1)	NL990001I2 (es)
NO (2)	NO175132C (es)
NZ (1)	NZ221424A (es)
PH (1)	PH27176A (es)
PT (1)	PT85525B (es)
SG (1)	SG122593G (es)
ZA (1)	ZA875947B (es)

Families Citing this family (34)

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DE19927689A1 (de) *	1999-06-17	2000-12-21	Gruenenthal Gmbh	Orale Darreichungsformen zur Verabreichung einer fixen Kombination von Tramadol und Diclofenac
EP1093814A1 (en) *	1999-10-22	2001-04-25	Boehringer Ingelheim Pharma KG	Use of dipyridamole or mopidamol in the manufacture of a medicament for the treatment and prevention of fibrin-dependent microcirculation disorders
US7064130B2 (en) *	2001-04-20	2006-06-20	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Use of radical-scavenging compounds for treatment and prevention of NO-dependent microcirculation disorders
US20040058056A1 (en) *	2001-07-06	2004-03-25	Shigemasa Osaki	Drug diffusion coatings, applications and methods
ATE502642T1 (de) *	2001-10-05	2011-04-15	Zalicus Inc	Kombinationen für die behandlung von immun- entzündlichen erkrankungen
TW200301135A (en) *	2001-12-27	2003-07-01	Otsuka Maryland Res Inst Inc	Pharmaceutical compositions comprising a multifunctional phosphodiesterase inhibitor and an adenosine uptake inhibitor
DE10209982A1 (de) *	2002-03-07	2003-09-25	Boehringer Ingelheim Pharma	Oral zu applizierende Darreichungsform für schwerlösliche basische Wirkstoffe
US20030181488A1 (en) *	2002-03-07	2003-09-25	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Administration form for the oral application of 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionic acid ethyl ester and the salts thereof
US7485322B2 (en) *	2002-12-24	2009-02-03	Lek Pharmaceuticals D.D.	Modified release pharmaceutical composition
CN1747734A (zh) *	2003-02-07	2006-03-15	贝林格尔·英格海姆国际有限公司	潘生丁或单哌潘生丁在治疗和预防mmp－9－依赖性疾病中的用途
DE10306179A1 (de)	2003-02-13	2004-08-26	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Verwendung von Dipyridamol in Kombination mit Acetylsalicylsäure und einem Angiotensin II-Antagonisten zur Schlaganfall-Prophylaxe
AU2004231306A1 (en) *	2003-04-24	2004-11-04	Boehringer Ingelheim International Gmbh	Use of dipyridamole or mopidamole for treatment and prevention of thrombo-embolic diseases and disorders caused by excessive formation of thrombin and/or by elevated expression of thrombin receptors
US7041286B2 (en) *	2003-07-23	2006-05-09	Nerenberg Arnold P	Composition for mitigating a pernicious thrombotic event
TW200517114A (en) *	2003-10-15	2005-06-01	Combinatorx Inc	Methods and reagents for the treatment of immunoinflammatory disorders
US20090048173A1 (en) *	2004-05-13	2009-02-19	Wolfgang Eisert	Use Of Dipyridamole For Treatment Of Resistance To Platelet Inhibitors
EP2559430B1 (en)	2005-03-22	2015-06-24	Losan Pharma GmbH	Solubilized Ibuprofen
KR20080037732A (ko) *	2005-08-22	2008-04-30	노파르티스 아게	ｐＨ-의존성 약물, ｐＨ 개질제 및 지연제를 포함하는제약학적 조성물
CN103211779B (zh) *	2006-01-27	2016-03-16	阿代尔制药股份有限公司	包含弱碱性选择性5-羟色胺5-ht3阻断剂和有机酸的药物递送系统
RU2428176C2 (ru) *	2006-01-27	2011-09-10	Юранд, Инк.	Системы доставки лекарственного средства, содержащие слабоосновные лекарственные средства и органические кислоты
AU2006337643A1 (en)	2006-02-09	2007-08-16	Teva Pharmaceutical Industries Ltd.	Dipyridamole extended-release formulations and process for preparing same
CA2652773A1 (en) *	2006-05-22	2007-12-06	Combinatorx, Incorporated	Methods and compositions for the treatment of diseases or conditions associated with increased c-reactive protein, interleukin-6, or interferon-gamma levels
ITRM20060460A1 (it) *	2006-08-31	2006-11-30	Univ Roma	Uso di acido acetil salicilico in combinazione con inibitori dei canali mrp4 per il trattamento di pazienti resistenti a detto acido acetil salicilico
PL2120878T3 (pl) *	2007-02-09	2015-01-30	Alphapharm Pty Ltd	Postać dawkowania zawierająca dwa czynne składniki farmaceutyczne o różnych postaciach fizycznych
CA2737131A1 (en) *	2007-09-19	2009-03-26	Zalicus Inc.	Therapeutic regimens for the treatment of immunoinflammatory disorders
KR20100121601A (ko) *	2007-12-17	2010-11-18	콤비네이토릭스, 인코포레이티드	면역염증성 질환의 치료를 위한 치료요법
WO2009097156A1 (en) *	2008-02-01	2009-08-06	Barr Laboratories, Inc.	Pharmaceutical capsules comprising extended release dipyridamole pellets
US8133506B2 (en) *	2008-03-12	2012-03-13	Aptalis Pharmatech, Inc.	Drug delivery systems comprising weakly basic drugs and organic acids
JP2011515438A (ja)	2008-03-28	2011-05-19	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	酸ペレットの製造方法
WO2010036975A2 (en) *	2008-09-25	2010-04-01	Teva Pharmaceutical Industries Ltd.	Dipyridamole and acetylsalicylic acid formulations and process for preparing same
US20110003005A1 (en) *	2009-07-06	2011-01-06	Gopi Venkatesh	Methods of Treating PDNV and PONV with Extended Release Ondansetron Compositions
EP2361615A1 (en)	2010-02-19	2011-08-31	Alfred E. Tiefenbacher GmbH & Co. KG	Dipyridamole prolonged-release tablet
WO2012162492A1 (en) *	2011-05-24	2012-11-29	Teva Pharmaceutical Industries Ltd.	Compressed core comprising organic acids for a pharmaceutical composition
CN103239724A (zh) *	2013-05-27	2013-08-14	成都自豪药业有限公司	抗血栓形成的联合用药物及其药物组合物
EP3641748B1 (en) *	2017-06-19	2023-11-29	The Cleveland Clinic Foundation	Treating disease and promoting weight loss by inhibiting the tma/fmo3/tmao pathway

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2368272A1 (fr) *	1976-10-20	1978-05-19	Theramex	Compositions therapeutiques solides pour combattre l'agregation plaquettaire
FR2368280A1 (fr) *	1976-10-20	1978-05-19	Theramex	Nouvelle composition therapeutique presentant une activite anti-agregante plaquettaire, et son procede de preparation
LU77353A1 (es) *	1977-05-16	1979-01-19
DE3000979A1 (de) *	1980-01-12	1981-07-23	Dr. Karl Thomae Gmbh, 7950 Biberach	Neue dipyridamol-retardformen und verfahren zu ihrer herstellung
FR2513118A1 (fr) *	1981-09-18	1983-03-25	Rocador Sa	Composition pharmaceutique a base de dipyridamol et de sel d'aluminium de l'acide acetylsalicylique pour combattre l'agregation plaquettaire
ATE50497T1 (de) *	1984-07-21	1990-03-15	Hoechst Ag	Kombinationspraeparat aus pyrimido-pyrimidinen und o-acetylsalicylsaeure bzw. deren pharmakologisch vertraeglichen salzen und dessen verwendung.

1986
- 1986-08-13 DE DE19863627423 patent/DE3627423A1/de not_active Withdrawn
1987
- 1987-07-31 DE DE8787111104T patent/DE3767408D1/de not_active Expired - Lifetime
- 1987-07-31 DE DE2002199015 patent/DE10299015I2/de active Active
- 1987-07-31 EP EP87111104A patent/EP0257344B1/de not_active Expired - Lifetime
- 1987-07-31 ES ES87111104T patent/ES2020974B3/es not_active Expired - Lifetime
- 1987-07-31 AT AT87111104T patent/ATE59961T1/de active
- 1987-08-11 DD DD87305901A patent/DD263918A5/de not_active IP Right Cessation
- 1987-08-11 CA CA000544180A patent/CA1302272C/en not_active Expired - Lifetime
- 1987-08-11 PH PH35653A patent/PH27176A/en unknown
- 1987-08-12 NO NO873370A patent/NO175132C/no not_active IP Right Cessation
- 1987-08-12 IL IL83510A patent/IL83510A/xx not_active IP Right Cessation
- 1987-08-12 DK DK421187A patent/DK172236B1/da not_active IP Right Cessation
- 1987-08-12 ZA ZA875947A patent/ZA875947B/xx unknown
- 1987-08-12 AU AU76795/87A patent/AU603146B2/en not_active Expired
- 1987-08-12 JP JP62201688A patent/JP2593879B2/ja not_active Expired - Lifetime
- 1987-08-12 PT PT85525A patent/PT85525B/pt unknown
- 1987-08-12 IE IE215287A patent/IE60862B1/en not_active IP Right Cessation
- 1987-08-12 FI FI873492A patent/FI873492A7/fi not_active Application Discontinuation
- 1987-08-12 NZ NZ221424A patent/NZ221424A/xx unknown
- 1987-08-12 HU HU873652A patent/HU202404B/hu unknown
- 1987-08-13 KR KR87008873A patent/KR950009098B1/ko not_active Expired - Lifetime
1991
- 1991-03-29 GR GR91400406T patent/GR3001695T3/el unknown
1993
- 1993-11-11 SG SG122593A patent/SG122593G/en unknown
1994
- 1994-02-24 HK HK144/94A patent/HK14494A/xx not_active IP Right Cessation
1995
- 1995-04-12 US US08/421,351 patent/US6015577A/en not_active Expired - Lifetime
1997
- 1997-05-13 BR BR1100593-9A patent/BR1100593A/pt active IP Right Grant
1999
- 1999-01-06 NL NL990001C patent/NL990001I2/nl unknown
- 1999-07-01 NO NO1999014C patent/NO1999014I1/no unknown
2004
- 2004-05-24 CL CL200401252A patent/CL2004001252A1/es unknown

Also Published As

Publication number	Publication date
ATE59961T1 (de)	1991-02-15
DK421187D0 (da)	1987-08-12
KR950009098B1 (en)	1995-08-14
PT85525A (de)	1987-09-01
NZ221424A (en)	1989-11-28
IL83510A (en)	1992-02-16
NO175132C (no)	1994-09-07
PT85525B (pt)	1990-06-29
DE10299015I2 (de)	2005-06-16
AU603146B2 (en)	1990-11-08
NO175132B (no)	1994-05-30
FI873492A0 (fi)	1987-08-12
DK172236B1 (da)	1998-02-02
ZA875947B (en)	1989-04-26
IE60862B1 (en)	1994-08-24
EP0257344A1 (de)	1988-03-02
NO873370L (no)	1988-02-15
KR880002529A (ko)	1988-05-09
DE3627423A1 (de)	1988-02-18
BR1100593A (pt)	2002-04-02
HU202404B (en)	1991-03-28
DE3767408D1 (de)	1991-02-21
AU7679587A (en)	1988-02-18
IL83510A0 (en)	1988-01-31
JP2593879B2 (ja)	1997-03-26
FI873492L (fi)	1988-02-14
FI873492A7 (fi)	1988-02-14
CL2004001252A1 (es)	2005-03-04
NL990001I2 (nl)	2000-04-03
DE10299015I1 (de)	2002-10-10
NO1999014I1 (no)	1999-07-01
IE872152L (en)	1988-02-13
US6015577A (en)	2000-01-18
HUT44937A (en)	1988-05-30
PH27176A (en)	1993-04-02
DK421187A (da)	1988-02-14
HK14494A (en)	1994-03-04
GR3001695T3 (en)	1992-11-23
CA1302272C (en)	1992-06-02
DD263918A5 (de)	1989-01-18
JPS6348219A (ja)	1988-02-29
NO873370D0 (no)	1987-08-12
NL990001I1 (nl)	1999-03-01
EP0257344B1 (de)	1991-01-16
SG122593G (en)	1994-06-10

Publication	Publication Date	Title
ES2020974B3 (es)	1991-10-16	Medicamente conteniendo dipiridamol o mopidamol y o-acido acetilsalicilico o sus sales tratables fisiologicamente, procedimiento para su fabricacion y su utilizacion para combatir la formacion de trombos
BR9406746A (pt)	1996-03-19	Composto processo para sua preparaçao preparado farmacêutico uso de um composto processo para a obtençao da inibiçao de trombina em um organismo humano ou animale fragmento estrutural
DK395789D0 (da)	1989-08-11	Anvendelse af alfa-aminoboronsyrederivater til fremstilling af et laegemiddel til terapi eller profylakse af virussygdomme
DE3667605D1 (de)	1990-01-25	Windel zur verhuetung von wundliegen.
DK112287A (da)	1987-09-06	Anvendelse af 2-alkoxy-n-(1-azabicyclo-oe2,2,2aaoct-3-yl)-benzamider og -thiobenzamider samt farmaceutisk acceptable syreadditionssalte deraf som laegemidler
ATE84716T1 (de)	1993-02-15	4-chinolincarbonsaeure-derivate, brauchbar zur behandlung von haut- und muco-epithelialgewebekrankheiten.
MX3375A (es)	1993-12-01	Procedimiento de preparacion de nuevas benzamidas y sus sales, producto obtenido y composicion farmaceutica que lo incluye.
ES2038216T3 (es)	1993-07-16	Procedimiento para la preparacion de 5-(3-alquil-5-t-butil-4-hidroxi-fenil)-2-amino-6h-1,3,4-tiadazinas y su empleo.
IT8721115A0 (it)	1987-06-30	Fitopreparato per la cura di affezioni cutanee.
ES2020925B3 (es)	1991-10-16	Nuevas sales cristalinas de ariloxipropanolaminas, procedimiento para su preparacion y utilizacion de las mismas.
EP0349143A3 (en)	1990-10-03	Use of phytic acid or its salts for the prevention or treatment of hepatic diseases
NO893326D0 (no)	1989-08-18	Fremgangsmaate for noeytralisering av svovelsyre inneholdende sinkioner.
SE8101963L (sv)	1981-10-24	Monohydrerad isoftalsyrapikolylamid, forfarande for dess framstellning samt farmaceutisk anvendning derav
DK400887D0 (da)	1987-07-31	Anvendelse af 15-deoxyspergualin til fremstilling af et laegemiddel
ES553273A0 (es)	1987-05-16	Nuevo procedimiento para la obtencion de sales complejas ferricas del acido l,l'-(1,2-etanodiildiimino)-bis(5-carboxi-2-hidroxibencenoactico)
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