ES2024363A6 - Process for obtaining 1-([1,1'-diphenyl]-4- ylphenylmethyl)-1H-imidazole - Google Patents
Process for obtaining 1-([1,1'-diphenyl]-4- ylphenylmethyl)-1H-imidazoleInfo
- Publication number
- ES2024363A6 ES2024363A6 ES9003259A ES9003259A ES2024363A6 ES 2024363 A6 ES2024363 A6 ES 2024363A6 ES 9003259 A ES9003259 A ES 9003259A ES 9003259 A ES9003259 A ES 9003259A ES 2024363 A6 ES2024363 A6 ES 2024363A6
- Authority
- ES
- Spain
- Prior art keywords
- imidazole
- diphenyl
- ylphenylmethyl
- obtaining
- activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Substances C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 title abstract 5
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N diphenyl Chemical group C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 abstract 3
- 230000001857 anti-mycotic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 239000003444 phase transfer catalyst Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Process for obtaining 1-([1,1'-diphenyl]-4- ylphenylmethyl)-1H-imidazole. Comprises reacting 4-(1,1'-diphenyl)- ylphenylchloromethane with imidazole. The reaction can be carried out in an organic solvent such as acetonitrile and in the presence of a phase transfer catalyst like BBDE C1. The compound obtained has pharmacological activity, especially in vivo and in vitro antimycotic activity. <IMAGE>
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9003259A ES2024363A6 (en) | 1990-12-20 | 1990-12-20 | Process for obtaining 1-([1,1'-diphenyl]-4- ylphenylmethyl)-1H-imidazole |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9003259A ES2024363A6 (en) | 1990-12-20 | 1990-12-20 | Process for obtaining 1-([1,1'-diphenyl]-4- ylphenylmethyl)-1H-imidazole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2024363A6 true ES2024363A6 (en) | 1992-02-16 |
Family
ID=8270136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES9003259A Expired - Lifetime ES2024363A6 (en) | 1990-12-20 | 1990-12-20 | Process for obtaining 1-([1,1'-diphenyl]-4- ylphenylmethyl)-1H-imidazole |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES2024363A6 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116874429A (en) * | 2023-06-28 | 2023-10-13 | 山东创新药物研发有限公司 | Preparation method of medicinal bifonazole |
-
1990
- 1990-12-20 ES ES9003259A patent/ES2024363A6/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116874429A (en) * | 2023-06-28 | 2023-10-13 | 山东创新药物研发有限公司 | Preparation method of medicinal bifonazole |
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