ES2024363A6 - Procedimiento para la obtencion de 1-(* 1,1'-bifenel*-4-ilfenilmetil)-1 h-imidazol. - Google Patents
Procedimiento para la obtencion de 1-(* 1,1'-bifenel*-4-ilfenilmetil)-1 h-imidazol.Info
- Publication number
- ES2024363A6 ES2024363A6 ES9003259A ES9003259A ES2024363A6 ES 2024363 A6 ES2024363 A6 ES 2024363A6 ES 9003259 A ES9003259 A ES 9003259A ES 9003259 A ES9003259 A ES 9003259A ES 2024363 A6 ES2024363 A6 ES 2024363A6
- Authority
- ES
- Spain
- Prior art keywords
- imidazole
- diphenyl
- ylphenylmethyl
- obtaining
- activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Substances C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 title abstract 5
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N diphenyl Chemical group C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 abstract 3
- 230000001857 anti-mycotic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 239000003444 phase transfer catalyst Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE 1-([1,1''-BIFENIL]-4-ILFENILMETIL)-1H-IMIDAZOL. COMPRENDE HACER REACCIONAR 4-(1,1''-BIFENIL)-ILFENILCLOROMETANO CON IMIDAZOL. LA REACCION PUEDE LLEVARSE A CABO EN UN DISOLVENTE ORGANICO COMO ACETONITRILO Y EN PRESENCIA DE UN CATALIZADOR DE TRANSFERENCIA DE FASE COMO BBDE C1. EL COMPUESTO OBTENIDO PRESENTA ACTIVIDAD FARMACOLOGICA, EN ESPECIAL ANTIMICOTICA <IN VIVO> E <IN VITRO>.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9003259A ES2024363A6 (es) | 1990-12-20 | 1990-12-20 | Procedimiento para la obtencion de 1-(* 1,1'-bifenel*-4-ilfenilmetil)-1 h-imidazol. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9003259A ES2024363A6 (es) | 1990-12-20 | 1990-12-20 | Procedimiento para la obtencion de 1-(* 1,1'-bifenel*-4-ilfenilmetil)-1 h-imidazol. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2024363A6 true ES2024363A6 (es) | 1992-02-16 |
Family
ID=8270136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES9003259A Expired - Lifetime ES2024363A6 (es) | 1990-12-20 | 1990-12-20 | Procedimiento para la obtencion de 1-(* 1,1'-bifenel*-4-ilfenilmetil)-1 h-imidazol. |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES2024363A6 (es) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116874429A (zh) * | 2023-06-28 | 2023-10-13 | 山东创新药物研发有限公司 | 一种药用联苯苄唑的制备方法 |
-
1990
- 1990-12-20 ES ES9003259A patent/ES2024363A6/es not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116874429A (zh) * | 2023-06-28 | 2023-10-13 | 山东创新药物研发有限公司 | 一种药用联苯苄唑的制备方法 |
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