ES2026554T3 - Nuevas sulfonamidas derivadas de diarilmetanos y sus procedimientos de preparacion, asi como las composiciones farmaceuticas que las contienen. - Google Patents

Nuevas sulfonamidas derivadas de diarilmetanos y sus procedimientos de preparacion, asi como las composiciones farmaceuticas que las contienen.

Info

Publication number
ES2026554T3
ES2026554T3 ES198787400556T ES87400556T ES2026554T3 ES 2026554 T3 ES2026554 T3 ES 2026554T3 ES 198787400556 T ES198787400556 T ES 198787400556T ES 87400556 T ES87400556 T ES 87400556T ES 2026554 T3 ES2026554 T3 ES 2026554T3
Authority
ES
Spain
Prior art keywords
pct
diarylmethanes
image
well
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787400556T
Other languages
English (en)
Inventor
Pierre Roger
Jean-Paul Fournier
Alain Martin
Jean Choay
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Application granted granted Critical
Publication of ES2026554T3 publication Critical patent/ES2026554T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/18—Radicals substituted by singly bound hetero atoms other than halogen by sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Epoxy Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

LA INVENCION TIENE POR OBJETO NUEVOS COMPUESTOS QUE RESPONDEN A LA FORMULA (I) EN LA CUAL: W REPRESENTA C=O, CH2 O CHOH; Z REPRESENTA FORMULA (II); R1 Y R2 REPRESENTAN PRINCIPALMENTE C1 O F; R,R'' Y R" REPRESENTAN PRINCIPALMENTE H; X REPRESENTA PRINCIPALMENTE CH2; Y REPRESENTA PRINCIPALMENTE COOH; U Y V SON DOS NUMEROS ENTEROS DE 0 A 2; P Y Q VALEN 0 O 1; N Y M SON DOS NUMEROS ENTEROS QUE VARIAN DE 0 A 10 Y T VALE 0 O 1; EL NUMERO TOTAL DE ATOMOS DE CARBONO DE LA CADENA (CH2)N(1CH)T-X-1CH -(CH2)M Y VARIAN DE 2 A 20 ASI COMO SUS SALES FISIOLOGICAMENTE ACEPTABLES OBTENIDAS CON ACIDOS ORGANICOS O MINERALES. ESTOS COMPUESTOS SE UTILIZAN PARA LA PREPARACION DE MEDICAMENTOS QUE POSEEN, SOBRE TODO, PROPIEDADES ANTIINFLAMATORIAS.
ES198787400556T 1986-03-12 1987-03-12 Nuevas sulfonamidas derivadas de diarilmetanos y sus procedimientos de preparacion, asi como las composiciones farmaceuticas que las contienen. Expired - Lifetime ES2026554T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8603537A FR2598412B1 (fr) 1986-03-12 1986-03-12 Nouveaux derives de diarylcetones et leurs procedes de preparation et les compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
ES2026554T3 true ES2026554T3 (es) 1992-05-01

Family

ID=9333058

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787400556T Expired - Lifetime ES2026554T3 (es) 1986-03-12 1987-03-12 Nuevas sulfonamidas derivadas de diarilmetanos y sus procedimientos de preparacion, asi como las composiciones farmaceuticas que las contienen.

Country Status (16)

Country Link
US (1) US4980349A (es)
EP (1) EP0238401B1 (es)
JP (1) JPS63502666A (es)
AT (1) ATE66208T1 (es)
AU (1) AU598248B2 (es)
CA (1) CA1296003C (es)
DE (1) DE3772074D1 (es)
DK (1) DK587387A (es)
ES (1) ES2026554T3 (es)
FR (1) FR2598412B1 (es)
GR (1) GR3002488T3 (es)
IL (1) IL81878A (es)
NZ (1) NZ219604A (es)
PT (1) PT84473B (es)
WO (1) WO1987005601A2 (es)
ZA (1) ZA871802B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5391705A (en) * 1991-03-15 1995-02-21 Merrell Dow Pharmaceuticals Inc. Polyfluorinated tripeptide thrombin inhibitors
US6069232A (en) * 1995-10-02 2000-05-30 Hoechst Marion Roussel, Inc. Polyfluoroalkyl tryptophan tripeptide thrombin inhibitors
US5739354A (en) * 1996-03-26 1998-04-14 Hoechst Marion Roussel, Inc. Process for the preparation of N-methyl-D-phenylalanyl-N- 1- 3- (aminoiminomethyl)amino!propyl!-3,3-difluoro-2-oxohexyl!-L-prolinamide
ATE501997T1 (de) 2003-11-20 2011-04-15 Solvay Verfahren zur herstellung von dichlorpropanol
CN106366000A (zh) * 2016-08-30 2017-02-01 枣阳凤泽精细化工有限公司 一种2‑氯‑5‑硝基二苯甲酮的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA634170A (en) * 1962-01-09 Schraufstatter Ernst Aromatic sulfanamides
US3666779A (en) * 1967-07-15 1972-05-30 Hoechst Ag Sulfonamido carboxylic acids
JPS518939B2 (es) * 1971-12-29 1976-03-22
FR2201883B1 (es) * 1972-10-05 1975-10-31 Roussel Uclaf
GB1447054A (en) * 1973-06-28 1976-08-25 American Home Prod 2-n-alkyl-2-imidazolinyl-phenyl ketones
CA1072359A (en) * 1974-10-08 1980-02-26 Hiroyuki Konishi Method for controlling the growth of plants
US4198519A (en) * 1976-07-30 1980-04-15 Beecham Group Limited Anti-inflammatory compounds
DE3000377A1 (de) * 1980-01-07 1981-07-09 Boehringer Mannheim Gmbh, 6800 Mannheim Neue sulfonamide, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
FR2504528A1 (fr) * 1981-04-23 1982-10-29 Choay Sa Dialcoxy (2,4) benzenesulfonamides n-substitues
EP0068968B1 (fr) * 1981-06-16 1985-09-18 Choay S.A. Nouveaux médicaments contenant à titre de substance active des composés du type arylbenzènesulfonamide et leurs procédés de préparation

Also Published As

Publication number Publication date
IL81878A (en) 1991-06-30
WO1987005601A3 (fr) 1988-03-24
EP0238401B1 (fr) 1991-08-14
DK587387A (da) 1988-01-08
JPS63502666A (ja) 1988-10-06
AU598248B2 (en) 1990-06-21
EP0238401A2 (fr) 1987-09-23
PT84473A (fr) 1987-04-01
GR3002488T3 (en) 1992-12-30
ZA871802B (en) 1987-11-25
EP0238401A3 (en) 1987-12-02
DE3772074D1 (de) 1991-09-19
PT84473B (pt) 1989-10-04
ATE66208T1 (de) 1991-08-15
WO1987005601A2 (fr) 1987-09-24
CA1296003C (fr) 1992-02-18
FR2598412B1 (fr) 1988-10-21
NZ219604A (en) 1990-06-26
DK587387D0 (da) 1987-11-10
US4980349A (en) 1990-12-25
IL81878A0 (en) 1987-10-20
AU7167087A (en) 1987-10-09
FR2598412A1 (fr) 1987-11-13

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