NO904269L - Fremgangsmaate for fremstilling av 24-homo-vitamin-d-derivater. - Google Patents

Fremgangsmaate for fremstilling av 24-homo-vitamin-d-derivater.

Info

Publication number: NO904269L
Authority: NO; Norway
Prior art keywords: carbon atoms; homo; vitamin; derivatives; preparing
Prior art date: 1989-10-02

Application number

NO90904269A

Other languages

English (en)

Other versions

NO178923C (no

NO904269D0 (no

NO178923B (no

Inventor

Gerald Kirsch

Guenter Neef

Katica Schwarz

Matthias Braeutigam

Ruth Thieroff-Ekerdt

Petra Rach

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-10-02

Filing date

1990-10-01

Publication date

1991-04-03

1990-10-01 Application filed by Schering Ag filed Critical Schering Ag

1990-10-01 Publication of NO904269D0 publication Critical patent/NO904269D0/no

1991-04-03 Publication of NO904269L publication Critical patent/NO904269L/no

1996-03-25 Publication of NO178923B publication Critical patent/NO178923B/no

1996-07-03 Publication of NO178923C publication Critical patent/NO178923C/no

Links

238000000034 method Methods 0.000 title abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 5
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000004423 acyloxy group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000002837 carbocyclic group Chemical group 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
230000035755 proliferation Effects 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nutrition Science (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Steroid Compounds (AREA)
Medicinal Preparation (AREA)

NO904269A 1989-10-02 1990-10-01 Analogifremgangsmåte for fremstilling av terapeutisk aktive 24-homo-vitamin-D-derivater NO178923C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE3933034A DE3933034A1 (de)	1989-10-02	1989-10-02	24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung

Publications (4)

Publication Number	Publication Date
NO904269D0 NO904269D0 (no)	1990-10-01
NO904269L true NO904269L (no)	1991-04-03
NO178923B NO178923B (no)	1996-03-25
NO178923C NO178923C (no)	1996-07-03

Family

ID=6390762

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO904269A NO178923C (no)	1989-10-02	1990-10-01	Analogifremgangsmåte for fremstilling av terapeutisk aktive 24-homo-vitamin-D-derivater

Country Status (18)

Country	Link
US (1)	US5665716A (no)
EP (1)	EP0421561B1 (no)
JP (1)	JPH03246273A (no)
CN (2)	CN1031705C (no)
AT (1)	ATE103893T1 (no)
AU (1)	AU639717B2 (no)
CA (1)	CA2026671C (no)
DD (1)	DD299178A5 (no)
DE (2)	DE3933034A1 (no)
DK (1)	DK0421561T3 (no)
ES (1)	ES2052166T3 (no)
FI (1)	FI93643C (no)
HU (1)	HU210032B (no)
IE (1)	IE71227B1 (no)
IL (1)	IL95872A (no)
NO (1)	NO178923C (no)
PT (1)	PT95473B (no)
ZA (1)	ZA907876B (no)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5260290A (en) *	1990-02-14	1993-11-09	Wisconsin Alumni Research Foundation	Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5030772A (en) *	1990-02-14	1991-07-09	Deluca Hector F	Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US20040009958A1 (en) *	1991-01-08	2004-01-15	Bone Care International, Inc.	Methods for preparation and use of 1alpha,24(S)-dihydroxyvitamin D2
DE4200783C2 (de) *	1992-01-10	1997-02-06	Schering Ag	(5Z,7E,22E)-(1S,3R,24S)-24-Benzyl-9,10-secochola-5,7,10(19),22-tetraen-1,3,24-triol, Verfahren zur Herstellung und Pharmazeutische Präparate
IL107185A (en) *	1992-10-06	1998-02-22	Schering Ag	Vitamin d, 25-carboxylic acid derivatives and pharmaceutical compositions containing the same
DE4328217C2 (de) *	1993-08-21	1996-01-11	Lohmann Therapie Syst Lts	Therapeutisches System zur Behandlung der Psoriasis
US6242434B1 (en) *	1997-08-08	2001-06-05	Bone Care International, Inc.	24-hydroxyvitamin D, analogs and uses thereof
DE19619036A1 (de)	1996-04-30	1997-11-13	Schering Ag	Neue Vitamin D-Derivate mit carbo- oder heterocyclischen Substituenten an C-25, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
US5939408A (en)	1996-05-23	1999-08-17	Hoffman-La Roche Inc.	Vitamin D3 analogs
US20020128240A1 (en) *	1996-12-30	2002-09-12	Bone Care International, Inc.	Treatment of hyperproliferative diseases using active vitamin D analogues
US20030129194A1 (en) *	1997-02-13	2003-07-10	Bone Care International, Inc.	Targeted therapeutic delivery of vitamin D compounds
DE19935771A1 (de)	1999-07-23	2001-02-01	Schering Ag	Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
IL153378A0 (en) *	2000-07-18	2003-07-06	Bone Care Internat Inc	STABILIZED 1alpha-HYDROXY VITAMIN D
DE10156596A1 (de) *	2001-11-13	2003-05-28	Schering Ag	Vitamin D-Derivate mit Acyloxygruppen in der Seitenkette, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
EP1470220B1 (en) *	2002-01-10	2011-10-05	Teva Pharmaceutical Industries, Ltd.	Selective enzymatic esterification and solvolysis of epimeric vitamin d analog and separation of the epimers
AU2003275987A1 (en) *	2002-06-13	2003-12-31	Teva Pharmaceutical Industries Ltd.	Epimerization of analogs of vitamin d
US7094775B2 (en)	2004-06-30	2006-08-22	Bone Care International, Llc	Method of treating breast cancer using a combination of vitamin D analogues and other agents
KR20110113664A (ko) *	2006-08-29	2011-10-17	테바 파마슈티컬 인더스트리즈 리미티드	비타민 ｄ 및 코르티코스테로이드를 포함하는 약학 조성물
EP2299809B1 (en) *	2008-06-17	2018-10-17	Ben Gurion University Of The Negev R&D Authority	Substituted cyclohexylidene-ethylidene-octahydro-indene compounds
AU2010208323B2 (en)	2009-01-27	2016-03-10	Berg Llc	Vitamin D3 and analogs thereof for alleviating side effects associated with chemotherapy
EP2464357B1 (en)	2009-08-14	2019-05-22	Berg LLC	Vitamin d3 and analogs thereof for treating alopecia
SG10201709894RA (en)	2013-05-29	2018-01-30	Berg Llc	Preventing or mitigating chemotherapy induced alopecia using vitamin d
US10548908B2 (en) *	2016-09-15	2020-02-04	Nostopharma, LLC	Compositions and methods for preventing and treating heterotopic ossification and pathologic calcification

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS62500301A (ja) *	1984-10-04	1987-02-05	ウイスコンシン　アラムナイ　リサ−チ　フオンデ−シヨン	２４―ホモビタミンｄ誘導体
WO1987003282A1 (fr) *	1985-11-21	1987-06-04	Taisho Pharmaceutical Co., Ltd.	Derive de la vitamine d3
US4927815A (en) *	1988-04-29	1990-05-22	Wisconsin Alumni Research Foundation	Compounds effective in inducing cell differentiation and process for preparing same
US4847012A (en) *	1988-04-29	1989-07-11	Wisconsin Alumni Research Foundation	Vitamin D related compounds and processes for their preparation
US5030772A (en) *	1990-02-14	1991-07-09	Deluca Hector F	Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US5260290A (en) *	1990-02-14	1993-11-09	Wisconsin Alumni Research Foundation	Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives

1989
- 1989-10-02 DE DE3933034A patent/DE3933034A1/de not_active Withdrawn
1990
- 1990-10-01 AT AT90250249T patent/ATE103893T1/de not_active IP Right Cessation
- 1990-10-01 ES ES90250249T patent/ES2052166T3/es not_active Expired - Lifetime
- 1990-10-01 CN CN90108993A patent/CN1031705C/zh not_active Expired - Fee Related
- 1990-10-01 EP EP90250249A patent/EP0421561B1/de not_active Expired - Lifetime
- 1990-10-01 DE DE90250249T patent/DE59005254D1/de not_active Expired - Lifetime
- 1990-10-01 PT PT95473A patent/PT95473B/pt not_active IP Right Cessation
- 1990-10-01 DD DD90344338A patent/DD299178A5/de not_active IP Right Cessation
- 1990-10-01 DK DK90250249.1T patent/DK0421561T3/da active
- 1990-10-01 NO NO904269A patent/NO178923C/no not_active IP Right Cessation
- 1990-10-01 HU HU906284A patent/HU210032B/hu not_active IP Right Cessation
- 1990-10-02 US US07/592,017 patent/US5665716A/en not_active Expired - Fee Related
- 1990-10-02 ZA ZA907876A patent/ZA907876B/xx unknown
- 1990-10-02 CA CA002026671A patent/CA2026671C/en not_active Expired - Fee Related
- 1990-10-02 IL IL9587290A patent/IL95872A/en not_active IP Right Cessation
- 1990-10-02 AU AU63715/90A patent/AU639717B2/en not_active Ceased
- 1990-10-02 FI FI904850A patent/FI93643C/fi not_active IP Right Cessation
- 1990-10-02 IE IE352090A patent/IE71227B1/en not_active IP Right Cessation
- 1990-10-02 JP JP2263263A patent/JPH03246273A/ja active Pending
1994
- 1994-08-18 CN CN94115050A patent/CN1053103C/zh not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AU639717B2 (en)	1993-08-05
US5665716A (en)	1997-09-09
ZA907876B (en)	1992-04-29
IE903520A1 (en)	1991-04-10
JPH03246273A (ja)	1991-11-01
PT95473B (pt)	1997-07-31
NO178923C (no)	1996-07-03
IL95872A (en)	1995-03-15
IL95872A0 (en)	1991-07-18
CN1053103C (zh)	2000-06-07
CA2026671C (en)	1998-12-08
CN1031705C (zh)	1996-05-01
HU210032B (en)	1995-01-30
ATE103893T1 (de)	1994-04-15
FI904850A0 (fi)	1990-10-02
DE59005254D1 (de)	1994-05-11
CN1051907A (zh)	1991-06-05
EP0421561A3 (en)	1991-06-12
NO904269D0 (no)	1990-10-01
EP0421561A2 (de)	1991-04-10
IE71227B1 (en)	1997-02-12
FI93643B (fi)	1995-01-31
AU6371590A (en)	1991-04-11
HU906284D0 (en)	1991-03-28
FI93643C (fi)	1995-05-10
DE3933034A1 (de)	1991-04-11
CA2026671A1 (en)	1991-04-03
EP0421561B1 (de)	1994-04-06
HUT55751A (en)	1991-06-28
ES2052166T3 (es)	1994-07-01
DK0421561T3 (da)	1994-07-25
CN1106666A (zh)	1995-08-16
PT95473A (pt)	1991-06-25
DD299178A5 (de)	1992-04-02
NO178923B (no)	1996-03-25

Legal Events

Date	Code	Title	Description
2001-05-28	MM1K	Lapsed by not paying the annual fees	Free format text: LAPSED IN APRIL 2001

Publication	Publication Date	Title
NO904269D0 (no)	1990-10-01	Fremgangsmaate for fremstilling av 24-homo-vitamin-d-derivater.
NL300396I1 (nl)	2009-10-01	Nieuwe derivaten met naftalinestructuren, werkwijze voor de bereiding ervan en de farmaceutische preparaten die deze bevatten
FR2392971A1 (fr)	1978-12-29	Derives de l'acide prostanoique, leur preparation et medicament contenant ces substances
FR2360587A1 (fr)	1978-03-03	Nouveaux derives d'amino-alcoyl-furannes utiles comme medicaments
ES510599A0 (es)	1983-06-16	Procedimiento para la preparacion de acidos (2-oxo-3-tetrahidrotienilcarbamoil)-alquiltio aceticos.
ES8606282A1 (es)	1986-04-16	Un procedimiento de preparar derivados de acidos quinolin- ynaftiridin-carboxilicos
FR2355796A1 (fr)	1978-01-20	Procede de preparation de fluorures d'acides perfluoro-alcoxy-propioniques
FR2390448A1 (fr)	1978-12-08	Derives azido d'acide penicillanique utiles dans la preparation de medicaments
FR2386544A1 (fr)	1978-11-03	Procede pour la preparation de derives d'imidazodiazepine
ATE108440T1 (de)	1994-07-15	Arylaralkylether, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung.
FR2377367A1 (fr)	1978-08-11	Procede de preparation d'alcoxy-cetones
ATE10743T1 (de)	1984-12-15	Benzopyranylether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel und zwischenprodukte.
IT1230595B (it)	1991-10-28	Perossiacidi immido derivati
DK0401623T3 (da)	2000-07-17	Fremgangsmåde til fremstilling af 7-(3-amino- og 3-aminomethyl-1-pyrrolidinyl)-3-quinoloncarboxylsyrer og -napthyridoncarbo
FR2373285A1 (fr)	1978-07-07	Nouveaux derives du coenzyme b 12, procede de preparation et application a titre de medicaments de ces nouveaux produits
ES487631A1 (es)	1980-06-16	Procedimiento para la obtencion de hexahidro-1,4-oxazepinas
SE8903312D0 (sv)	1989-10-09	New 2-carbonyl substituted n,n'-di-(trimethoxybenzol)piperazines, process for preparing the same and therapeutical compounds containing them
FR2446841A1 (fr)	1980-08-14	Procede de preparation de 1a,3b-dihydroxy-d5-steroides
FR2366289A1 (fr)	1978-04-28	Nouveaux derives de l'imidazo(5,1-a)isoquinoleine, leur preparation et leur application comme medicaments
SE9203824L (sv)	1993-06-28	Bensofuranylimidazol-derivat, foerfarande foer framstaellning daerav och terapeutiska kompositioner innehaallande desamma
FR2380272A1 (fr)	1978-09-08	Derives de la coumarine et d'indane-diode, utilisables comme medicament
FR2373514A1 (fr)	1978-07-07	Derives d'ammonium quaternaire de l'adamantane utiles notamment comme agents antimicrobiens et leur procede de preparation
SE8903313L (sv)	1990-04-12	Nya 2-metoxikarbonyl-substituerade n,n'-di-(trimetoxibensoyl)-piperaziner, foerfarande foer framstaellning daerav och terapeutiska foereningar innehaallande dem
ATE29133T1 (de)	1987-09-15	Troponon-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung.
GB995864A (en)	1965-06-23	New derivatives of hydantoins