ES2029845T3 - Procedimiento para preparar derivados de 1,5-benzotiazepina - Google Patents

Procedimiento para preparar derivados de 1,5-benzotiazepina

Info

Publication number
ES2029845T3
ES2029845T3 ES198787400750T ES87400750T ES2029845T3 ES 2029845 T3 ES2029845 T3 ES 2029845T3 ES 198787400750 T ES198787400750 T ES 198787400750T ES 87400750 T ES87400750 T ES 87400750T ES 2029845 T3 ES2029845 T3 ES 2029845T3
Authority
ES
Spain
Prior art keywords
benzotiazepine
derivatives
preparing
procedure
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787400750T
Other languages
English (en)
Inventor
Jean-Claude Muller
Andre Dumas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Application granted granted Critical
Publication of ES2029845T3 publication Critical patent/ES2029845T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/36—Seven-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Hydrogenated Pyridines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

COMPUESTO DE FORMULA GENERAL (I) EN LA QUE R REPRESENTA EL HIDROGENO O UN GRUPO ALQUILO EN C1-C4 LINEAL O RAMIFICADO, Y R1 Y R2, SEPARADAMENTE, REPRESENTAN CADA UNO UN GRUPO ALQUILO EN C1-C4 LINEAL O RAMIFICADO, O BIEN R1 Y R2 JUNTOS, REPRESENTAN UN GRUPO TETRAMETILENO O PENTAMETILENO. APLICACION EN TERAPEUTICA.
ES198787400750T 1986-04-15 1987-04-06 Procedimiento para preparar derivados de 1,5-benzotiazepina Expired - Lifetime ES2029845T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8605346A FR2597097B1 (fr) 1986-04-15 1986-04-15 Derives de benzothiazepine-1, 5, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
ES2029845T3 true ES2029845T3 (es) 1992-10-01

Family

ID=9334233

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787400750T Expired - Lifetime ES2029845T3 (es) 1986-04-15 1987-04-06 Procedimiento para preparar derivados de 1,5-benzotiazepina

Country Status (18)

Country Link
US (1) US4743599A (es)
EP (1) EP0242265B1 (es)
JP (1) JPS62242674A (es)
KR (1) KR870010029A (es)
AT (1) ATE63908T1 (es)
AU (1) AU586086B2 (es)
CA (1) CA1283657C (es)
DE (1) DE3770321D1 (es)
DK (1) DK191587A (es)
ES (1) ES2029845T3 (es)
FI (1) FI871637A7 (es)
FR (1) FR2597097B1 (es)
GR (1) GR3002225T3 (es)
HU (1) HU196776B (es)
IL (1) IL82181A0 (es)
NO (1) NO167286C (es)
PT (1) PT84680B (es)
ZA (1) ZA872683B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2703564B2 (ja) * 1987-07-31 1998-01-26 田辺製薬株式会社 １，５−ベンゾチアゼピン誘導体
FR2621584B1 (fr) * 1987-10-07 1991-05-24 Synthelabo Derives de benzothiazepine-1,5, leur preparation et leur application en therapeutique
FR2630109B1 (fr) * 1988-04-19 1991-11-29 Synthelabo Derives de ((n-(amino-2 oxo-2 ethyl)methylamino)-2 ethyl)-5 hydroxy-3 (methoxy-4 phenyl)-2 dihydro-2,3 5h-benzothiazepine-1,5 one-4, leur preparation et leur application en therapeutique
US4902684A (en) * 1988-06-20 1990-02-20 E. R. Squibb & Sons, Inc. Benzazepine and benzothiazepine derivatives
JP2863534B2 (ja) * 1988-10-24 1999-03-03 マリオン ラボラトリーズ，インコーポレイティド 医薬組成物
US4952692A (en) * 1989-04-04 1990-08-28 E. R. Squibb & Sons, Inc. Benzazepine derivatives
FR2669632B1 (fr) * 1990-11-22 1993-01-15 Synthelabo Derives de benzo-1, 5-thiazepine, leur preparation et leur application en therapeutique.
FR2672599B1 (fr) * 1991-02-08 1994-11-18 Synthelabo Derives de benzothiazepine-1,5, leur preparation et leur application en therapeutique.
US5580867A (en) * 1994-09-09 1996-12-03 Universite De Montreal Myocardial protection during ischemia and reperfusion

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3341519A (en) * 1965-04-28 1967-09-12 Squibb & Sons Inc Novel benzoxazines, benzothiazines, benzoxazepins and benzothiazepins
US3562257A (en) * 1967-10-28 1971-02-09 Tanabe Seiyaku Co Benzothiazepine derivatives

Also Published As

Publication number Publication date
HU196776B (en) 1989-01-30
FI871637A7 (fi) 1987-10-16
US4743599A (en) 1988-05-10
EP0242265A1 (fr) 1987-10-21
DK191587D0 (da) 1987-04-14
AU586086B2 (en) 1989-06-29
PT84680A (fr) 1987-05-01
NO871575D0 (no) 1987-04-14
NO167286C (no) 1991-10-23
EP0242265B1 (fr) 1991-05-29
FI871637A0 (fi) 1987-04-14
GR3002225T3 (en) 1992-12-30
FR2597097A1 (fr) 1987-10-16
ZA872683B (en) 1987-11-25
KR870010029A (ko) 1987-11-30
PT84680B (pt) 1989-12-29
JPS62242674A (ja) 1987-10-23
NO871575L (no) 1987-10-16
ATE63908T1 (de) 1991-06-15
FR2597097B1 (fr) 1988-12-02
DK191587A (da) 1987-10-16
HUT45518A (en) 1988-07-28
CA1283657C (en) 1991-04-30
NO167286B (no) 1991-07-15
AU7156487A (en) 1987-10-22
IL82181A0 (en) 1987-10-30
DE3770321D1 (de) 1991-07-04

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