ES2034010T3 - Formulacion para la administracion de farmacos por via oral y metodo para prepararla. - Google Patents
Formulacion para la administracion de farmacos por via oral y metodo para prepararla.Info
- Publication number
- ES2034010T3 ES2034010T3 ES198888107564T ES88107564T ES2034010T3 ES 2034010 T3 ES2034010 T3 ES 2034010T3 ES 198888107564 T ES198888107564 T ES 198888107564T ES 88107564 T ES88107564 T ES 88107564T ES 2034010 T3 ES2034010 T3 ES 2034010T3
- Authority
- ES
- Spain
- Prior art keywords
- oral
- drug delivery
- formulation
- compositions
- drugs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 238000009472 formulation Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 2
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 238000012377 drug delivery Methods 0.000 abstract 2
- 229940126701 oral medication Drugs 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- 108010010803 Gelatin Proteins 0.000 abstract 1
- 239000004698 Polyethylene Substances 0.000 abstract 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940121375 antifungal agent Drugs 0.000 abstract 1
- 239000003429 antifungal agent Substances 0.000 abstract 1
- 239000001768 carboxy methyl cellulose Substances 0.000 abstract 1
- 239000008273 gelatin Substances 0.000 abstract 1
- 229920000159 gelatin Polymers 0.000 abstract 1
- 235000019322 gelatine Nutrition 0.000 abstract 1
- 235000011852 gelatine desserts Nutrition 0.000 abstract 1
- 239000000416 hydrocolloid Substances 0.000 abstract 1
- 239000002480 mineral oil Substances 0.000 abstract 1
- 235000010446 mineral oil Nutrition 0.000 abstract 1
- 210000002200 mouth mucosa Anatomy 0.000 abstract 1
- 239000003883 ointment base Substances 0.000 abstract 1
- 239000001814 pectin Substances 0.000 abstract 1
- 235000010987 pectin Nutrition 0.000 abstract 1
- 229920001277 pectin Polymers 0.000 abstract 1
- -1 polyethylene Polymers 0.000 abstract 1
- 229920000573 polyethylene Polymers 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 abstract 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
Landscapes
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
Abstract
SE PRESENTAN SISTEMAS DE LIBERACION QUE INCLUYEN UNO O MAS SOLIDOS HIDROCOLOIDALES , TALES COMO GELATINA, PECTINA Y CARBOXIMETILCELULOSA SODICA, Y PREFERIBLEMENTE MEZCLAS DE ELLOS, CUYOS SOLIDOS CONTIENEN MENOS DEL 5% EN PESO DE HUMEDAD Y PREFERIBLEMENTE COMPRENDEN MENOS DEL 50% EN PESO DE LA FORMULACION TOTAL; Y UNA BASE UNTOSA TAL COMO ACEITE MINERAL QUE CONTIENE POLIETILENO DISPERSADO (PLASTIBASE). ESTAS COMPOSICIONES DE LIBERACION PARA MEDICAMENTOS ORALES PUEDEN USARSE PARA LIBERAR INGREDIENTES ACTIVOS PARA LA MUCOSA ORAL TALES COMO ESTEROIDES, AGENTES ANTIFUNGICOS, AGENTES ANTIBACTERIANOS Y SIMILARES Y NO SE ENDURECEN POR ALMACENAMIENTO PROLONGADO O POR ENVASADO EN RECIPIENTES.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/052,297 US4867970A (en) | 1987-05-21 | 1987-05-21 | Moistureless oral drug delivery formulation and method for preparing same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2034010T3 true ES2034010T3 (es) | 1993-04-01 |
Family
ID=21976676
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES198888107564T Expired - Lifetime ES2034010T3 (es) | 1987-05-21 | 1988-05-11 | Formulacion para la administracion de farmacos por via oral y metodo para prepararla. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4867970A (es) |
| EP (1) | EP0291838B1 (es) |
| JP (1) | JPS63303924A (es) |
| AT (1) | ATE79023T1 (es) |
| AU (1) | AU1372888A (es) |
| CA (1) | CA1314479C (es) |
| DE (1) | DE3873410T2 (es) |
| DK (1) | DK278288A (es) |
| ES (1) | ES2034010T3 (es) |
| GR (1) | GR3006146T3 (es) |
| HU (1) | HU199071B (es) |
| IE (1) | IE63548B1 (es) |
| ZA (1) | ZA882290B (es) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5446070A (en) * | 1991-02-27 | 1995-08-29 | Nover Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
| US5234957A (en) * | 1991-02-27 | 1993-08-10 | Noven Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
| US5110809A (en) * | 1988-03-21 | 1992-05-05 | Bristol-Myers Squibb Company | Antifungal gel formulations |
| US4988500A (en) * | 1989-09-29 | 1991-01-29 | The Procter & Gamble Company | Oral compositions |
| AU652022B2 (en) * | 1991-02-12 | 1994-08-11 | C.R. Bard Inc. | Injectable medical device |
| US5332576A (en) * | 1991-02-27 | 1994-07-26 | Noven Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
| US5192802A (en) * | 1991-09-25 | 1993-03-09 | Mcneil-Ppc, Inc. | Bioadhesive pharmaceutical carrier |
| WO1993021905A1 (en) * | 1992-04-23 | 1993-11-11 | Berlex Laboratories, Inc. | Bioadhesive solid mineral oil emulsion |
| US5310961A (en) * | 1993-07-02 | 1994-05-10 | Affinity Biotech, Inc. | Neomorphic ibuprofen |
| WO1996002275A1 (en) * | 1994-07-20 | 1996-02-01 | Toyama Chemical Co., Ltd. | Sustained-release oral ointment |
| US5993787A (en) * | 1996-09-13 | 1999-11-30 | Johnson & Johnson Consumer Products, Inc. | Composition base for topical therapeutic and cosmetic preparations |
| US5800832A (en) * | 1996-10-18 | 1998-09-01 | Virotex Corporation | Bioerodable film for delivery of pharmaceutical compounds to mucosal surfaces |
| US5955097A (en) | 1996-10-18 | 1999-09-21 | Virotex Corporation | Pharmaceutical preparation applicable to mucosal surfaces and body tissues |
| US20050048102A1 (en) * | 1997-10-16 | 2005-03-03 | Virotex Corporation | Pharmaceutical carrier device suitable for delivery of pharmaceutical compounds to mucosal surfaces |
| US6103266A (en) * | 1998-04-22 | 2000-08-15 | Tapolsky; Gilles H. | Pharmaceutical gel preparation applicable to mucosal surfaces and body tissues |
| JP4653282B2 (ja) * | 2000-05-23 | 2011-03-16 | 昭和薬品化工株式会社 | ミノサイクリン含有組成物 |
| TNSN03137A1 (en) | 2001-06-22 | 2005-12-23 | Pfizer Prod Inc | PHARMACEUTICAL COMPOSITIONS COMPRISING LOW SOLUBILITY AND / OR ACID SENSITIVE DRUGS AND NEUTRALIZED ACID POLYMERS. |
| DE10157260B4 (de) * | 2001-11-22 | 2005-12-15 | Pharmoxid Arznei Gmbh + Co. Kg | Streichfähige Salbe mit Ozoniden und Peroxiden von Fettsäuren oder deren Estern |
| US20040091551A1 (en) * | 2002-11-13 | 2004-05-13 | Al-Karim Damji | Topical composition and application system |
| GB2398496A (en) * | 2003-02-20 | 2004-08-25 | Reckitt Benckiser Healthcare | Suspensions of water-swellable polymer particles which are substantially water-free or contain insufficient water to fully swell the particles |
| RU2242203C1 (ru) * | 2003-08-01 | 2004-12-20 | Губарева Наталия Николаевна | Пленочная повязка |
| RU2242204C1 (ru) * | 2003-08-01 | 2004-12-20 | Губарева Наталия Николаевна | Атравматичная повязка |
| JP2005097271A (ja) * | 2003-08-20 | 2005-04-14 | Matsumoto Shika Univ | 抗真菌剤用組成物 |
| EP1508329A1 (en) * | 2003-08-20 | 2005-02-23 | Matsumoto Dental University | Composition for an antifungal agent for suppressing fungal growth in an oral cavity |
| EP1510205B1 (en) * | 2003-09-01 | 2008-03-26 | JPM - The Jordanian Pharmaceutical Manufacturing Co. Ltd. | Universal controlled-release composition comprising xanthan gum and sodium alginate |
| US20050074494A1 (en) * | 2003-10-06 | 2005-04-07 | Xiu-Xiu Cheng | Itraconazole immediate release formulation |
| WO2006031848A2 (en) * | 2004-09-15 | 2006-03-23 | Ivax Corporation | Corticosteroid topical dispersion with low content of surfactant |
| SE530184C2 (sv) * | 2005-12-23 | 2008-03-18 | Kjell Stenberg | Bioadhesiv farmaceutisk filmkomposition innehållande lågviskösa alginater |
| DK2054031T3 (en) | 2006-07-21 | 2016-05-17 | Biodelivery Sciences Int Inc | Transmucosal delivery devices with improved uptake |
| US8701671B2 (en) | 2011-02-04 | 2014-04-22 | Joseph E. Kovarik | Non-surgical method and system for reducing snoring |
| US9549842B2 (en) | 2011-02-04 | 2017-01-24 | Joseph E. Kovarik | Buccal bioadhesive strip and method of treating snoring and sleep apnea |
| US12257272B2 (en) | 2015-12-24 | 2025-03-25 | Seed Health, Inc. | Method and system for reducing the likelihood of developing depression in an individual |
| US11844720B2 (en) | 2011-02-04 | 2023-12-19 | Seed Health, Inc. | Method and system to reduce the likelihood of dental caries and halitosis |
| US11951139B2 (en) | 2015-11-30 | 2024-04-09 | Seed Health, Inc. | Method and system for reducing the likelihood of osteoporosis |
| US11998479B2 (en) | 2011-02-04 | 2024-06-04 | Seed Health, Inc. | Method and system for addressing adverse effects on the oral microbiome and restoring gingival health caused by sodium lauryl sulphate exposure |
| US12533312B2 (en) | 2011-02-04 | 2026-01-27 | Seed Health, Inc. | Method and system for preventing sore throat in humans |
| US11951140B2 (en) | 2011-02-04 | 2024-04-09 | Seed Health, Inc. | Modulation of an individual's gut microbiome to address osteoporosis and bone disease |
| US12279989B2 (en) | 2011-02-04 | 2025-04-22 | Seed Health, Inc. | Method and system for increasing beneficial bacteria and decreasing pathogenic bacteria in the oral cavity |
| AU2012296346A1 (en) | 2011-08-18 | 2014-04-03 | Biodelivery Sciences International, Inc. | Abuse-resistant mucoadhesive devices for delivery of buprenorphine |
| US9901539B2 (en) | 2011-12-21 | 2018-02-27 | Biodelivery Sciences International, Inc. | Transmucosal drug delivery devices for use in chronic pain relief |
| US12005085B2 (en) | 2013-12-20 | 2024-06-11 | Seed Health, Inc. | Probiotic method and composition for maintaining a healthy vaginal microbiome |
| US11826388B2 (en) | 2013-12-20 | 2023-11-28 | Seed Health, Inc. | Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation |
| US11998574B2 (en) | 2013-12-20 | 2024-06-04 | Seed Health, Inc. | Method and system for modulating an individual's skin microbiome |
| US12329783B2 (en) | 2013-12-20 | 2025-06-17 | Seed Health, Inc. | Method and system to improve the health of a person's skin microbiome |
| US11839632B2 (en) | 2013-12-20 | 2023-12-12 | Seed Health, Inc. | Topical application of CRISPR-modified bacteria to treat acne vulgaris |
| US12246043B2 (en) | 2013-12-20 | 2025-03-11 | Seed Health, Inc. | Topical application to treat acne vulgaris |
| US11969445B2 (en) | 2013-12-20 | 2024-04-30 | Seed Health, Inc. | Probiotic composition and method for controlling excess weight, obesity, NAFLD and NASH |
| US11980643B2 (en) | 2013-12-20 | 2024-05-14 | Seed Health, Inc. | Method and system to modify an individual's gut-brain axis to provide neurocognitive protection |
| US11833177B2 (en) | 2013-12-20 | 2023-12-05 | Seed Health, Inc. | Probiotic to enhance an individual's skin microbiome |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2628187A (en) | 1950-05-06 | 1953-02-10 | Res Prod Corp | Medicinal mineral oil vehicle thickened with polyethylene |
| US3029187A (en) * | 1958-02-20 | 1962-04-10 | Steinhardt Amos | Gelating adhesive pharmaceutical preparations |
| US3029188A (en) * | 1958-02-20 | 1962-04-10 | Olin Mathieson | Gelatin adhesive pharmaceutical preparations |
| FR1367858A (fr) * | 1962-08-11 | 1964-07-24 | Hoechst Ag | Bases de pommades pour les muqueuses et leur préparation |
| US3312594A (en) * | 1963-06-21 | 1967-04-04 | Squibb & Sons Inc | Longlasting troche |
| GB1063185A (en) * | 1965-04-27 | 1967-03-30 | Astra Ab | Improvements in the administration of veterinary medicines |
| US3594467A (en) * | 1968-10-09 | 1971-07-20 | Richardson Merrell Inc | Long-lasting troche |
| US3984571A (en) * | 1970-03-10 | 1976-10-05 | E. R. Squibb & Sons, Inc. | Hydrocolloid containing liquid carrier for a diagnostic or therapeutic agent |
| JPS5138412A (en) * | 1974-09-24 | 1976-03-31 | Nippon Kayaku Kk | Kokoseizai no seiho |
| JPS5386011A (en) * | 1977-10-31 | 1978-07-29 | Nippon Kayaku Co Ltd | Preparation of paste |
| DE3013839A1 (de) * | 1979-04-13 | 1980-10-30 | Freunt Ind Co Ltd | Verfahren zur herstellung einer aktivierten pharmazeutischen zusammensetzung |
| JPS6043328B2 (ja) * | 1981-04-16 | 1985-09-27 | 昭和薬品化工株式会社 | 軟膏の基剤 |
| JPS58206534A (ja) * | 1982-05-26 | 1983-12-01 | Taisho Pharmaceut Co Ltd | 口腔薬基剤 |
| US4542020A (en) * | 1984-08-17 | 1985-09-17 | E. R. Squibb & Sons, Inc. | Long-lasting adhesive antifungal suppositories |
| EP0256611A1 (en) * | 1986-08-08 | 1988-02-24 | Squibb Japan Inc. | Oral drug delivery systems |
-
1987
- 1987-05-21 US US07/052,297 patent/US4867970A/en not_active Expired - Lifetime
-
1988
- 1988-03-25 AU AU13728/88A patent/AU1372888A/en not_active Abandoned
- 1988-03-30 ZA ZA882290A patent/ZA882290B/xx unknown
- 1988-05-11 AT AT88107564T patent/ATE79023T1/de not_active IP Right Cessation
- 1988-05-11 DE DE8888107564T patent/DE3873410T2/de not_active Revoked
- 1988-05-11 ES ES198888107564T patent/ES2034010T3/es not_active Expired - Lifetime
- 1988-05-11 EP EP88107564A patent/EP0291838B1/en not_active Expired - Lifetime
- 1988-05-18 JP JP63122985A patent/JPS63303924A/ja active Pending
- 1988-05-20 DK DK278288A patent/DK278288A/da not_active Application Discontinuation
- 1988-05-20 HU HU882612A patent/HU199071B/hu unknown
- 1988-05-20 IE IE154088A patent/IE63548B1/en not_active IP Right Cessation
- 1988-05-24 CA CA000567487A patent/CA1314479C/en not_active Expired - Fee Related
-
1992
- 1992-11-04 GR GR920402471T patent/GR3006146T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK278288D0 (da) | 1988-05-20 |
| CA1314479C (en) | 1993-03-16 |
| DE3873410T2 (de) | 1993-01-21 |
| EP0291838B1 (en) | 1992-08-05 |
| GR3006146T3 (es) | 1993-06-21 |
| EP0291838A2 (en) | 1988-11-23 |
| AU1372888A (en) | 1988-11-24 |
| ATE79023T1 (de) | 1992-08-15 |
| US4867970A (en) | 1989-09-19 |
| JPS63303924A (ja) | 1988-12-12 |
| DK278288A (da) | 1988-11-22 |
| HU199071B (en) | 1990-01-29 |
| IE881540L (en) | 1988-11-21 |
| DE3873410D1 (de) | 1992-09-10 |
| ZA882290B (en) | 1988-09-22 |
| IE63548B1 (en) | 1995-05-17 |
| HUT49280A (en) | 1989-09-28 |
| EP0291838A3 (en) | 1989-05-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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