ES2036170T3 - Nuevas carbaciclinas, procedimiento para su preparacion asi como a su utilizacion como medicamentos. - Google Patents

Nuevas carbaciclinas, procedimiento para su preparacion asi como a su utilizacion como medicamentos.

Info

Publication number
ES2036170T3
ES2036170T3 ES198686116566T ES86116566T ES2036170T3 ES 2036170 T3 ES2036170 T3 ES 2036170T3 ES 198686116566 T ES198686116566 T ES 198686116566T ES 86116566 T ES86116566 T ES 86116566T ES 2036170 T3 ES2036170 T3 ES 2036170T3
Authority
ES
Spain
Prior art keywords
carbaciclines
medicines
procedure
preparation
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198686116566T
Other languages
English (en)
Inventor
Helmut Prof. Vorbruggen
Ulrich Dr. Klar
Bob Nieuweboer
Claus Steffen Dr. Sturzebecher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of ES2036170T3 publication Critical patent/ES2036170T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
    • C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
    • C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

LA INVENCION SE REFIERE A DERIVADOS DE CARBACICLINA DE LA FORMULA GENERAL (I) DONDE LOS SUSTITUYENTES A, W, D, E, R4, R5, R9, Y1 E Y2 SON COMO SE HAN DESCRITO EN LA MEMORIA Y EN LAS REIVINDICACIONES, A SUS SALES CON BASES FISIOLOGICAMENTE COMPATIBLES, A PROCEDIMIENTOS PARA SU OBTENCION Y A SU UTILIZACION COMO MEDICAMENTOS.
ES198686116566T 1985-11-29 1986-11-28 Nuevas carbaciclinas, procedimiento para su preparacion asi como a su utilizacion como medicamentos. Expired - Lifetime ES2036170T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853542745 DE3542745A1 (de) 1985-11-29 1985-11-29 Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
ES2036170T3 true ES2036170T3 (es) 1993-05-16

Family

ID=6287504

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198686116566T Expired - Lifetime ES2036170T3 (es) 1985-11-29 1986-11-28 Nuevas carbaciclinas, procedimiento para su preparacion asi como a su utilizacion como medicamentos.

Country Status (12)

Country Link
EP (1) EP0224275B1 (es)
JP (1) JPS63501871A (es)
AT (1) ATE55119T1 (es)
AU (1) AU605127B2 (es)
CA (1) CA1275095A (es)
DE (2) DE3542745A1 (es)
DK (1) DK396387D0 (es)
ES (1) ES2036170T3 (es)
GR (1) GR3000884T3 (es)
HU (2) HUT43561A (es)
IE (1) IE59345B1 (es)
WO (1) WO1987003283A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3725031A1 (de) * 1987-07-24 1989-02-02 Schering Ag Neue 9-substituierte carbacyclinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US5374654A (en) * 1987-07-24 1994-12-20 Schering Aktiengesellschaft 9-substituted carbacyclin derivatives, processes for their preparation, and their use as medicinal agents
DE4134156A1 (de) * 1991-10-11 1993-04-15 Schering Ag 9-substituierte bicyclo(3.3.0)octan-derivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5215949B1 (es) * 1970-06-15 1977-05-06
US4420632A (en) * 1980-04-15 1983-12-13 The Upjohn Company Composition and process
US4487961A (en) * 1982-02-16 1984-12-11 The Upjohn Company 9-Substituted carbacyclin analogs
US4588823A (en) * 1982-02-16 1986-05-13 The Upjohn Company 9-substituted carbacyclin analogs
DE3428266A1 (de) * 1984-07-27 1986-01-30 Schering AG, 1000 Berlin und 4709 Bergkamen Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
DK396387A (da) 1987-07-29
EP0224275A1 (de) 1987-06-03
EP0224275B1 (de) 1990-08-01
IE59345B1 (en) 1994-02-09
AU605127B2 (en) 1991-01-10
DK396387D0 (da) 1987-07-29
WO1987003283A1 (fr) 1987-06-04
AU6724987A (en) 1987-07-01
HUT43561A (en) 1987-11-30
DE3673135D1 (de) 1990-09-06
GR3000884T3 (en) 1991-11-15
JPS63501871A (ja) 1988-07-28
DE3542745A1 (de) 1987-08-06
IE863130L (en) 1987-05-29
ATE55119T1 (de) 1990-08-15
CA1275095A (en) 1990-10-09
HU206317B (en) 1992-10-28

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