ES2036472A1 - Procedimiento de obtencion de eritromicina 9-(0-((2-metoxietoxi)metil)oxima) (roxitromicina). - Google Patents
Procedimiento de obtencion de eritromicina 9-(0-((2-metoxietoxi)metil)oxima) (roxitromicina).Info
- Publication number
- ES2036472A1 ES2036472A1 ES919102152A ES9102152A ES2036472A1 ES 2036472 A1 ES2036472 A1 ES 2036472A1 ES 919102152 A ES919102152 A ES 919102152A ES 9102152 A ES9102152 A ES 9102152A ES 2036472 A1 ES2036472 A1 ES 2036472A1
- Authority
- ES
- Spain
- Prior art keywords
- oxima
- roxithromycin
- methyl
- translation
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 title abstract 4
- RXZBMPWDPOLZGW-XMRMVWPWSA-N (E)-roxithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=N/OCOCCOC)/[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 RXZBMPWDPOLZGW-XMRMVWPWSA-N 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 229960005224 roxithromycin Drugs 0.000 title abstract 3
- 229960003276 erythromycin Drugs 0.000 title abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 title abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 241000192125 Firmicutes Species 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- CXHHBNMLPJOKQD-UHFFFAOYSA-M methyl carbonate Chemical compound COC([O-])=O CXHHBNMLPJOKQD-UHFFFAOYSA-M 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 150000007530 organic bases Chemical class 0.000 abstract 1
- 239000002798 polar solvent Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
PROCEDIMIENTO DE OBTENCION DE ERITROMICINA 9-[0-[(2METOXIETOXI)METIL] OXIMA], DENOMINADA ROXITROMICINA, DE FORMULA I, BASADO EN TRATAR CON UNA BASE ORGANICA, PREFERENTEMENTE UN CARBONATO DE METAL ALCALINO O ALCALINO TERREO, UNA SAL DE 2-METOXIETOXIMETILAMONIO DE LA ERITROMICINA 9-OXIMA DE FORMULA V FORMULA DONDE X- SIGNIFICA UN ANION DERIVADO DE UN ACIDO MINERAL U ORGANICO; EL PROCESO TIENE LUGAR EN EL SENO DE UN DISOLVENTE POLAR NO ALCOHOLICO. LA ROXITROMICINA MUESTRA ACTIVIDAD ANTIBIOTICA FRENTE A BACTERIAS GRAM POSITIVAS.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9102152A ES2036472B1 (es) | 1991-10-01 | 1991-10-01 | Procedimiento de obtencion de eritromicina 9-(0-((2-metoxietoxi)metil)oxima) (roxitromicina). |
| PT10091392A PT100913A (pt) | 1991-10-01 | 1992-09-29 | Processo para a obtencao de eritromicina 9-{o-{(2-metoxietoxi)metil} oxima} (roxitromicina) |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9102152A ES2036472B1 (es) | 1991-10-01 | 1991-10-01 | Procedimiento de obtencion de eritromicina 9-(0-((2-metoxietoxi)metil)oxima) (roxitromicina). |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2036472A1 true ES2036472A1 (es) | 1993-05-16 |
| ES2036472B1 ES2036472B1 (es) | 1994-03-01 |
Family
ID=8273673
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES9102152A Expired - Fee Related ES2036472B1 (es) | 1991-10-01 | 1991-10-01 | Procedimiento de obtencion de eritromicina 9-(0-((2-metoxietoxi)metil)oxima) (roxitromicina). |
Country Status (2)
| Country | Link |
|---|---|
| ES (1) | ES2036472B1 (es) |
| PT (1) | PT100913A (es) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0985680A1 (en) * | 1998-09-10 | 2000-03-15 | Hovione Inter Ltd. | A process for the purification of roxithromycin |
| EP1004591A1 (en) * | 1998-11-24 | 2000-05-31 | Max India Limited | Process for preparing roxithromycin and derivatives thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES8200702A1 (es) * | 1980-01-11 | 1981-11-01 | Roussel Uclaf | Procedimiento para preparar derivados de la eritromicina |
-
1991
- 1991-10-01 ES ES9102152A patent/ES2036472B1/es not_active Expired - Fee Related
-
1992
- 1992-09-29 PT PT10091392A patent/PT100913A/pt not_active Application Discontinuation
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES8200702A1 (es) * | 1980-01-11 | 1981-11-01 | Roussel Uclaf | Procedimiento para preparar derivados de la eritromicina |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0985680A1 (en) * | 1998-09-10 | 2000-03-15 | Hovione Inter Ltd. | A process for the purification of roxithromycin |
| US6204368B1 (en) | 1998-09-10 | 2001-03-20 | Hovione Inter Ltd. | Process for the purification of roxithromycin |
| EP1004591A1 (en) * | 1998-11-24 | 2000-05-31 | Max India Limited | Process for preparing roxithromycin and derivatives thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| PT100913A (pt) | 1993-11-30 |
| ES2036472B1 (es) | 1994-03-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO1987007274A2 (en) | Antitumor compositions and their methods of use | |
| EP0245518A4 (en) | ISOFLAVONE DERIVATIVES, THEIR SALTS AND ONCOSTATIC AGENTS AND IMMUNOSUPPRESSANTS. | |
| AU8220187A (en) | Process for the selective preparation of alkenecarboxylic acid derivatives | |
| BR9807349A (pt) | Composto, processos para preparar um composto e para preparar 6-o-alquil eritromicina a. | |
| CA2019939A1 (en) | Hydrophobic nucleic acid probe | |
| FR2337477B1 (es) | ||
| IE811297L (en) | Macrolide antibiotics | |
| ES2101231T3 (es) | Procedimiento estereoselectivo de glicosilacion de anion. | |
| NO914239D0 (no) | Polyesterkjedeforlengede vinyleteruretanoligomerer | |
| FR2590255B1 (fr) | Procede de preparation de derives de la pteridine | |
| GR3003840T3 (es) | ||
| ES2036472A1 (es) | Procedimiento de obtencion de eritromicina 9-(0-((2-metoxietoxi)metil)oxima) (roxitromicina). | |
| IT8019526A0 (it) | Sistema di posizionamento regolabile per lampade da lavoro. | |
| AU564952B2 (en) | N,n-dimethylglycine ester of metronidazole | |
| AU534082B2 (en) | Isolation and purification of dipeptide sweeteners | |
| DE3885311D1 (de) | Vernetzbare, fluorhaltige Copolymere als Bindemittel für hochwitterungsstabile Lacke. | |
| CA2130618A1 (en) | Stereoselective process for preparing .beta.-anomer enriched 2-deoxy-2,2-difluoro-d-ribofuranosyl-3,5-hydroxy protected-1-alkyl and aryl sulfonate intermediates | |
| TW198171B (es) | ||
| FR2596755B1 (fr) | Procede de preparation de composes carbonyles ethyleniques | |
| ES459052A1 (es) | Un procedimiento para la produccion de la mezcla antibioticaa-35512. | |
| PT859795E (pt) | Processo para a preparacao de ferro-dextrano cristalino | |
| GR1001203B (el) | Μεθοδος παρασκευης της ενωσεως 24r-σκυμνολη. | |
| HUT49381A (en) | Electrolyte for galvanization | |
| JPS51137238A (en) | Movable double support lift for automobile maintenance | |
| ES2006280A6 (es) | Procedimiento para la obtencion de un derivado rifamicinico. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20000603 |