PT100913A - Processo para a obtencao de eritromicina 9-{o-{(2-metoxietoxi)metil} oxima} (roxitromicina) - Google Patents

Processo para a obtencao de eritromicina 9-{o-{(2-metoxietoxi)metil} oxima} (roxitromicina)

Info

Publication number: PT100913A
Authority: PT; Portugal
Prior art keywords: erythromycin; oxime; prepn; methyl; methoxy ethoxy
Prior art date: 1991-10-01

Application number

PT10091392A

Other languages

English (en)

Portuguese (pt)

Inventor

Alba Agusti Cruz

Eduard Elias Vilarelle

Antonio Ginebreda Marti

Original Assignee

Prodesfarma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-10-01

Filing date

1992-09-29

Publication date

1993-11-30

1992-09-29 Application filed by Prodesfarma Sa filed Critical Prodesfarma Sa

1993-11-30 Publication of PT100913A publication Critical patent/PT100913A/pt

Links

ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 title 2
241000192125 Firmicutes Species 0.000 title 1
230000003115 biocidal effect Effects 0.000 title 1
229960003276 erythromycin Drugs 0.000 title 1
150000002923 oximes Chemical class 0.000 title 1
KYTWXIARANQMCA-PGYIPVOXSA-N (3r,4s,5s,6r,7r,9r,10z,11s,12r,13s,14r)-6-[(2s,3r,4s,6r)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-10-hydroxyimino-4-[(2r,4r,5s,6s)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradec Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=N\O)/[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 KYTWXIARANQMCA-PGYIPVOXSA-N 0.000 abstract 1
RXZBMPWDPOLZGW-XMRMVWPWSA-N (E)-roxithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=N/OCOCCOC)/[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 RXZBMPWDPOLZGW-XMRMVWPWSA-N 0.000 abstract 1
HKPXIMZRDAHTAW-UHFFFAOYSA-N 2-methoxyethoxymethanamine Chemical class COCCOCN HKPXIMZRDAHTAW-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
230000001476 alcoholic effect Effects 0.000 abstract 1
150000001450 anions Chemical group 0.000 abstract 1
239000002798 polar solvent Substances 0.000 abstract 1

Landscapes

Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

PT10091392A 1991-10-01 1992-09-29 Processo para a obtencao de eritromicina 9-{o-{(2-metoxietoxi)metil} oxima} (roxitromicina) PT100913A (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ES9102152A ES2036472B1 (es)	1991-10-01	1991-10-01	Procedimiento de obtencion de eritromicina 9-(0-((2-metoxietoxi)metil)oxima) (roxitromicina).

Publications (1)

Publication Number	Publication Date
PT100913A true PT100913A (pt)	1993-11-30

Family

ID=8273673

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT10091392A PT100913A (pt)	1991-10-01	1992-09-29	Processo para a obtencao de eritromicina 9-{o-{(2-metoxietoxi)metil} oxima} (roxitromicina)

Country Status (2)

Country	Link
ES (1)	ES2036472B1 (es)
PT (1)	PT100913A (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT102202B (pt)	1998-09-10	2001-04-30	Hovione Sociedade Quimica S A	Processo para a purificacao de roxitromicina
DE69813244T2 (de) *	1998-11-24	2004-03-04	Jubilant Organosys Ltd.	Verfahren zur Herstellung von Roxithromycin und Derivate davon

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2473525A1 (fr) *	1980-01-11	1981-07-17	Roussel Uclaf	Nouvelles oximes derivees de l'erythromycine, leur procede de preparation et leur application comme medicaments

1991
- 1991-10-01 ES ES9102152A patent/ES2036472B1/es not_active Expired - Fee Related
1992
- 1992-09-29 PT PT10091392A patent/PT100913A/pt not_active Application Discontinuation

Also Published As

Publication number	Publication date
ES2036472A1 (es)	1993-05-16
ES2036472B1 (es)	1994-03-01

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Legal Events

Date	Code	Title	Description
1999-07-30	FC3A	Refusal	Effective date: 19990408