ES2037672T3 - Utilizacion de pteridinas y/o purinas o de un inhibidor de xantinoxidasa para la fabricacion de un medicamento para el tratamiento de enfermedades degenerativas de la retina condicionadas geneticamente. - Google Patents
Utilizacion de pteridinas y/o purinas o de un inhibidor de xantinoxidasa para la fabricacion de un medicamento para el tratamiento de enfermedades degenerativas de la retina condicionadas geneticamente.Info
- Publication number
- ES2037672T3 ES2037672T3 ES198787102094T ES87102094T ES2037672T3 ES 2037672 T3 ES2037672 T3 ES 2037672T3 ES 198787102094 T ES198787102094 T ES 198787102094T ES 87102094 T ES87102094 T ES 87102094T ES 2037672 T3 ES2037672 T3 ES 2037672T3
- Authority
- ES
- Spain
- Prior art keywords
- pteridines
- treatment
- xantinoxidase
- purines
- inhibitor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003814 drug Substances 0.000 title abstract 2
- 150000003195 pteridines Chemical class 0.000 title abstract 2
- 230000001143 conditioned effect Effects 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000003212 purines Chemical class 0.000 title 1
- 210000001525 retina Anatomy 0.000 title 1
- 208000017442 Retinal disease Diseases 0.000 abstract 2
- 206010038923 Retinopathy Diseases 0.000 abstract 1
- 230000003412 degenerative effect Effects 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 239000003064 xanthine oxidase inhibitor Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
UTILIZACION DE PTERIDINA Y/O PRECURSORES BIOQUIMICOS DE XANTINOXIDASA RETARDADA PARA EL TRATAMIENTO DE ENFERMEDADES DE RETINA DEGENERATIVAS ORIGINADAS GENETICAMENTE, ESPECIALMENTE RETINOPATIA PIGMENTOSA (RP) Y FABRICACION DE UN MEDICAMENTO CORRESPONDIENTE.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP87102094A EP0278040B1 (de) | 1987-02-13 | 1987-02-13 | Verwendung von Pteridinen und/oder Purinen oder eines Xanthinoxidase-Hemmers zur Herstellung eines Arzneimittels zur Behandlung von genetisch bedingten degenerativen Netzhauterkrankungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2037672T3 true ES2037672T3 (es) | 1993-07-01 |
Family
ID=8196754
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES198787102094T Expired - Lifetime ES2037672T3 (es) | 1987-02-13 | 1987-02-13 | Utilizacion de pteridinas y/o purinas o de un inhibidor de xantinoxidasa para la fabricacion de un medicamento para el tratamiento de enfermedades degenerativas de la retina condicionadas geneticamente. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4943575A (es) |
| EP (1) | EP0278040B1 (es) |
| JP (1) | JPS63239222A (es) |
| AT (1) | ATE66147T1 (es) |
| DE (1) | DE3772193D1 (es) |
| ES (1) | ES2037672T3 (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL1708690T3 (pl) | 2003-11-17 | 2017-01-31 | Biomarin Pharmaceutical Inc. | Leczenie fenyloketonurii za pomocą BH4 |
| KR20070084270A (ko) * | 2004-11-17 | 2007-08-24 | 바이오마린 파머수티컬 인크. | 안정한 정제 제형물 |
| US20090075992A1 (en) * | 2005-01-07 | 2009-03-19 | University Of Strathclyde | Pteridine Derivatives as Nitric Oxide Synthase Activators |
| US20060194800A1 (en) * | 2005-01-07 | 2006-08-31 | University Of Strathclyde | Pteridine derivatives as nitric oxide synthase activators |
| WO2007138103A1 (en) | 2006-06-01 | 2007-12-06 | Nobera Pharma, S.L. | Use of allopurinol for the treatment of palmar plantar erythrodysesthesia |
| EP2246057A1 (en) * | 2009-04-29 | 2010-11-03 | Nobera Pharma, S.L. | Use of allopurinol for the treatment of hand foot skin reaction |
| US9216178B2 (en) | 2011-11-02 | 2015-12-22 | Biomarin Pharmaceutical Inc. | Dry blend formulation of tetrahydrobiopterin |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE51421B1 (en) * | 1980-08-01 | 1986-12-24 | Smith & Nephew Ass | Ophthalmic compositions containing triamterene |
| US4425346A (en) * | 1980-08-01 | 1984-01-10 | Smith And Nephew Associated Companies Limited | Pharmaceutical compositions |
| EP0059524A1 (en) * | 1981-02-09 | 1982-09-08 | Smith and Nephew Associated Companies p.l.c. | Pharmaceutical composition containing aminopteridines or aminopyrimido(4,5-d)pyrimidines |
| JPS61194020A (ja) * | 1985-02-22 | 1986-08-28 | Dai Ichi Seiyaku Co Ltd | 網膜症治療剤 |
-
1987
- 1987-02-13 AT AT87102094T patent/ATE66147T1/de not_active IP Right Cessation
- 1987-02-13 EP EP87102094A patent/EP0278040B1/de not_active Expired - Lifetime
- 1987-02-13 ES ES198787102094T patent/ES2037672T3/es not_active Expired - Lifetime
- 1987-02-13 DE DE8787102094T patent/DE3772193D1/de not_active Expired - Fee Related
-
1988
- 1988-02-12 US US07/155,400 patent/US4943575A/en not_active Expired - Fee Related
- 1988-02-12 JP JP63030697A patent/JPS63239222A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE3772193D1 (de) | 1991-09-19 |
| US4943575A (en) | 1990-07-24 |
| JPS63239222A (ja) | 1988-10-05 |
| ATE66147T1 (de) | 1991-08-15 |
| EP0278040B1 (de) | 1991-08-14 |
| EP0278040A1 (de) | 1988-08-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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