ES2037792T3 - Un metodo para prevenir que se formen coagulos de sangre en el circuito extracorporal de un aparato de dialisis y una composicion util del mismo. - Google Patents
Un metodo para prevenir que se formen coagulos de sangre en el circuito extracorporal de un aparato de dialisis y una composicion util del mismo.Info
- Publication number
- ES2037792T3 ES2037792T3 ES198888117485T ES88117485T ES2037792T3 ES 2037792 T3 ES2037792 T3 ES 2037792T3 ES 198888117485 T ES198888117485 T ES 198888117485T ES 88117485 T ES88117485 T ES 88117485T ES 2037792 T3 ES2037792 T3 ES 2037792T3
- Authority
- ES
- Spain
- Prior art keywords
- forming
- same
- blood clots
- dialysis device
- preventing blood
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000502 dialysis Methods 0.000 title abstract 3
- 208000007536 Thrombosis Diseases 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000008280 blood Substances 0.000 abstract 2
- 210000004369 blood Anatomy 0.000 abstract 2
- JNWFIPVDEINBAI-UHFFFAOYSA-N [5-hydroxy-4-[4-(1-methylindol-5-yl)-5-oxo-1H-1,2,4-triazol-3-yl]-2-propan-2-ylphenyl] dihydrogen phosphate Chemical compound C1=C(OP(O)(O)=O)C(C(C)C)=CC(C=2N(C(=O)NN=2)C=2C=C3C=CN(C)C3=CC=2)=C1O JNWFIPVDEINBAI-UHFFFAOYSA-N 0.000 abstract 1
- 229960004120 defibrotide Drugs 0.000 abstract 1
- 238000001802 infusion Methods 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3672—Means preventing coagulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3672—Means preventing coagulation
- A61M1/3675—Deactivation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- External Artificial Organs (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
LA INTRODUCCION DE DEFIBROTIDE, COMO UN BOLO O POR INFUSION, NO ARRIBA DE LA MEMBRANA DE DIALISIS DEL CIRCUITO EXTRA CORPOREO DEL APARATO PARA LA DIALISIS EXTRA CORPORAL PREVIENE EL COAGULO DE SER FORMADO EN LA CORRIENTE SANGUINEA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT22399/87A IT1223322B (it) | 1987-10-23 | 1987-10-23 | Metodo per prevenire la formazione di coaguli sanguigni nel circuito extracorporeo di apparecchi di dialisi a composizione utile per esso |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2037792T3 true ES2037792T3 (es) | 1993-07-01 |
Family
ID=11195772
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES198888117485T Expired - Lifetime ES2037792T3 (es) | 1987-10-23 | 1988-10-20 | Un metodo para prevenir que se formen coagulos de sangre en el circuito extracorporal de un aparato de dialisis y una composicion util del mismo. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4938873A (es) |
| EP (1) | EP0317766B1 (es) |
| JP (1) | JP2703582B2 (es) |
| AT (1) | ATE83936T1 (es) |
| AU (1) | AU611495B2 (es) |
| CA (1) | CA1313819C (es) |
| DE (1) | DE3877154T2 (es) |
| ES (1) | ES2037792T3 (es) |
| GR (1) | GR3006730T3 (es) |
| IT (1) | IT1223322B (es) |
| PT (1) | PT88830B (es) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2034285A1 (en) * | 1990-02-09 | 1991-08-10 | Masao Yafuso | Method and system for monitoring of blood constituents in vivo |
| US5286388A (en) * | 1991-06-20 | 1994-02-15 | Ingram John M | Method for neutralizing heparin in whole blood taken from an extracorporeal circuit |
| US5977083A (en) * | 1991-08-21 | 1999-11-02 | Burcoglu; Arsinur | Method for using polynucleotides, oligonucleotides and derivatives thereof to treat various disease states |
| US6153109A (en) | 1994-09-16 | 2000-11-28 | Transonic Systmes, Inc. | Method and apparatus to measure blood flow rate in hemodialysis shunts |
| US6514419B2 (en) | 1994-09-16 | 2003-02-04 | Transonic Systems, Inc. | Method to measure blood flow and recirculation in hemodialysis shunts |
| US6610206B1 (en) | 1998-10-20 | 2003-08-26 | Advanced Renal Technologies | Buffered compositions for dialysis |
| US7670491B2 (en) * | 1998-10-20 | 2010-03-02 | Advanced Renal Technologies | Buffered compositions for dialysis |
| ES2322689T3 (es) * | 1999-09-22 | 2009-06-25 | Advanced Renal Technologies | Uso de un dializado con elevado contenido de citrato. |
| US6868739B1 (en) | 1999-10-19 | 2005-03-22 | Transonic Systems, Inc. | Method and apparatus to measure blood flow by an introduced volume change |
| EP1147777A1 (en) * | 2000-04-18 | 2001-10-24 | Crinos Industria Farmacobiologica S.p.A. | Combination of defibrotide and G-CSF and its use to activate haematopoietic progenitors |
| US8771663B2 (en) | 2000-04-18 | 2014-07-08 | Gentium Spa | Formulation having mobilising activity |
| US7351218B2 (en) | 2002-12-20 | 2008-04-01 | Gambro Lundia Ab | Device and process for extracorporeal treatment by citrate anticoagulant |
| ITMO20030293A1 (it) | 2003-10-29 | 2005-04-30 | Gambro Lundia Ab | Dispositivo per la determinazione del flusso di sangue in un circuito extracorporeo, nonche' apparecchiatura per il trattamento di sangue utilizzante lo stesso dispositivo. |
| EP3026122A1 (en) | 2014-11-27 | 2016-06-01 | Gentium S.p.A. | Cellular-based method for determining the potency of defibrotide |
| TW201909904A (zh) | 2017-08-03 | 2019-03-16 | 愛爾蘭商爵士製藥愛爾蘭有限責任公司 | 高濃度調配物 |
| CN112236149A (zh) | 2018-04-12 | 2021-01-15 | 贾兹制药公司 | 用于预防和治疗细胞因子释放综合征和与免疫耗竭相关的神经毒性的去纤苷 |
| US20220023533A1 (en) | 2018-12-07 | 2022-01-27 | Jazz Phrmaceticals Ireland Limited | Subcutaneous delivery of high concentration formulations |
| EP4110287A1 (en) | 2020-02-28 | 2023-01-04 | Jazz Pharmaceuticals Ireland Limited | Delivery of low viscosity formulations |
| WO2021212055A1 (en) | 2020-04-17 | 2021-10-21 | Jazz Pharmaceuticals Ireland Limited | Defibrotide treatment for the prevention of organ rejection and injury |
| TW202308659A (zh) | 2021-05-06 | 2023-03-01 | 愛爾蘭商爵士製藥愛爾蘭有限責任公司 | 用於急性呼吸窘迫症候群之治療及預防的去纖維蛋白多核苷酸 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3899481A (en) * | 1970-11-03 | 1975-08-12 | Crinos Industria Farmaco | Process for the controlled partial degradation of deoxyribonucleic acid extracted from animal organs |
| IT1043823B (it) * | 1970-11-03 | 1980-02-29 | Prephar | Procedimento per l estrazione di acidi nucleici da organi animali |
| DE2154279A1 (de) * | 1970-11-03 | 1972-05-25 | Crinos Industria Farmaco | Medikamente für das fibrinolytische System |
| US3946731A (en) * | 1971-01-20 | 1976-03-30 | Lichtenstein Eric Stefan | Apparatus for extracorporeal treatment of blood |
| JPS5226076B2 (es) * | 1972-10-06 | 1977-07-12 | ||
| US3809481A (en) * | 1972-12-01 | 1974-05-07 | Nasa | Single reflector interference spectrometer and drive system therefor |
| JPS5623961A (en) * | 1979-08-07 | 1981-03-06 | Kogyo Gijutsuin | Portable artificial kidney apparatus |
| JPS58180163A (ja) * | 1982-04-16 | 1983-10-21 | 日機装株式会社 | 血液浄化器における血球成分付着防止方法および装置 |
| JPS59183763A (ja) * | 1983-04-04 | 1984-10-18 | 第一電気株式会社 | 血液抗凝固剤使用減の血液透析方法および装置 |
| JPS59197255A (ja) * | 1983-04-22 | 1984-11-08 | 鐘淵化学工業株式会社 | 除去装置 |
| IT1170215B (it) * | 1983-09-12 | 1987-06-03 | Crinos Industria Farmaco | Composizione farmaceutica per il trattamento di stati di insufficienza renale acuta |
| IT1170214B (it) * | 1983-09-12 | 1987-06-03 | Crinos Industria Farmaco | Composizione farmaceutica per la cura delle arteriopatie periferiche |
| IT1206341B (it) * | 1984-02-16 | 1989-04-14 | Crinos Industria Farmaco | Composizione farmaceutica per il trattamento dell'ischemia acuta del miocardio. |
-
1987
- 1987-10-23 IT IT22399/87A patent/IT1223322B/it active
-
1988
- 1988-10-20 AT AT88117485T patent/ATE83936T1/de not_active IP Right Cessation
- 1988-10-20 ES ES198888117485T patent/ES2037792T3/es not_active Expired - Lifetime
- 1988-10-20 EP EP88117485A patent/EP0317766B1/en not_active Expired - Lifetime
- 1988-10-20 DE DE8888117485T patent/DE3877154T2/de not_active Expired - Fee Related
- 1988-10-21 PT PT88830A patent/PT88830B/pt not_active IP Right Cessation
- 1988-10-21 CA CA000580914A patent/CA1313819C/en not_active Expired - Fee Related
- 1988-10-24 JP JP63266265A patent/JP2703582B2/ja not_active Expired - Lifetime
- 1988-10-24 AU AU24158/88A patent/AU611495B2/en not_active Ceased
- 1988-10-24 US US07/261,539 patent/US4938873A/en not_active Expired - Fee Related
-
1992
- 1992-12-31 GR GR920403117T patent/GR3006730T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE83936T1 (de) | 1993-01-15 |
| AU2415888A (en) | 1989-04-27 |
| CA1313819C (en) | 1993-02-23 |
| EP0317766A1 (en) | 1989-05-31 |
| EP0317766B1 (en) | 1992-12-30 |
| JPH0292363A (ja) | 1990-04-03 |
| IT8722399A0 (it) | 1987-10-23 |
| IT1223322B (it) | 1990-09-19 |
| DE3877154T2 (de) | 1993-04-29 |
| PT88830B (pt) | 1993-01-29 |
| US4938873A (en) | 1990-07-03 |
| DE3877154D1 (de) | 1993-02-11 |
| JP2703582B2 (ja) | 1998-01-26 |
| GR3006730T3 (es) | 1993-06-30 |
| AU611495B2 (en) | 1991-06-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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