ES2037823T3 - Compuestos de beta-lactama y procedimiento para su produccion. - Google Patents

Compuestos de beta-lactama y procedimiento para su produccion.

Info

Publication number
ES2037823T3
ES2037823T3 ES198888301908T ES88301908T ES2037823T3 ES 2037823 T3 ES2037823 T3 ES 2037823T3 ES 198888301908 T ES198888301908 T ES 198888301908T ES 88301908 T ES88301908 T ES 88301908T ES 2037823 T3 ES2037823 T3 ES 2037823T3
Authority
ES
Spain
Prior art keywords
beta
compounds
formula
defined above
lactam
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888301908T
Other languages
English (en)
Inventor
Yasumitsu Tamura
Koichi Nishi
Junichi Haruta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Application granted granted Critical
Publication of ES2037823T3 publication Critical patent/ES2037823T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

SE PRODUCEN NUEVOS COMPUESTOS DE BETA-LACTAMA DE FORMULA (I) (EN LA QUE OR1 ES UN HIDROXILO PROTEGIDO O SIN PROTEGER; R2 ES ALQUILO DE 1 A 7 C O ARILO Y R3 ES HIDROGENO O UN SILILO TRI-SUSTITUIDO), A PARTIR DE COMPUESTOS DE AZETIDINONA DE FORMULA (II) (EN LA QUE OR1 ES EL ANTES DEFINIDO Y X ES UN GRUPO ELECTRONEGATIVO) POR REACCION DE: A) ESTANNILALENOS DE FORMULA R2CH=C=CH-SNR27 (SIENDO R2 EL ANTES DEFINIDO Y R7 ALQUILO DE 1 A 4 C O FENILO, O B) UN COMPUESTO METALICO DE FORMULA R2-CH(M)C=CH (DONDE R2 ES EL ANTES DEFINIDO Y M ES MG, HALOGENO, LITIO O UN GRUPO ESTER DE ACIDO TITANICO O BORICO) PARA OBTENER LOS CITADOS COMPUESTOS DE BETA-LACTAMA EN LOS QUE R3 ES HIDROGENO. LOSCOMPUESTOS DE BETA-LACTAMA SON UTILES PARA SINTETIZAR COMPUESTOS DE 1BETA-METILCARBAPENEM.
ES198888301908T 1987-03-06 1988-03-04 Compuestos de beta-lactama y procedimiento para su produccion. Expired - Lifetime ES2037823T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62052816A JPS63218659A (ja) 1987-03-06 1987-03-06 β−ラクタム化合物およびその製造法

Publications (1)

Publication Number Publication Date
ES2037823T3 true ES2037823T3 (es) 1993-07-01

Family

ID=12925365

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888301908T Expired - Lifetime ES2037823T3 (es) 1987-03-06 1988-03-04 Compuestos de beta-lactama y procedimiento para su produccion.

Country Status (6)

Country Link
EP (1) EP0282241B1 (es)
JP (1) JPS63218659A (es)
AT (1) ATE66234T1 (es)
DE (1) DE3864163D1 (es)
ES (1) ES2037823T3 (es)
GR (1) GR3002478T3 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5068232A (en) * 1990-04-10 1991-11-26 American Cyanamid Company Novel 2-substituted alkyl-3-carboxy carbapenems as antibiotics and a method of producing them

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0171064B1 (en) * 1984-08-06 1995-07-12 Fujisawa Pharmaceutical Co., Ltd. Azetidinone derivative and processes for production thereof
JPS62103063A (ja) * 1985-10-29 1987-05-13 Sagami Chem Res Center アゼチジノン誘導体の製造方法

Also Published As

Publication number Publication date
GR3002478T3 (en) 1992-12-30
EP0282241A1 (en) 1988-09-14
ATE66234T1 (de) 1991-08-15
JPS63218659A (ja) 1988-09-12
EP0282241B1 (en) 1991-08-14
DE3864163D1 (de) 1991-09-19

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