ES2042625T5 - Uso de una prostaglandina en combinacion con un agente bloqueante adrenergico para la reduccion de presion intraocular. - Google Patents
Uso de una prostaglandina en combinacion con un agente bloqueante adrenergico para la reduccion de presion intraocular.Info
- Publication number
- ES2042625T5 ES2042625T5 ES88104999T ES88104999T ES2042625T5 ES 2042625 T5 ES2042625 T5 ES 2042625T5 ES 88104999 T ES88104999 T ES 88104999T ES 88104999 T ES88104999 T ES 88104999T ES 2042625 T5 ES2042625 T5 ES 2042625T5
- Authority
- ES
- Spain
- Prior art keywords
- intraocular pressure
- blocking agent
- adrenergic blocking
- eye
- prostaglandine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000004410 intraocular pressure Effects 0.000 title abstract 5
- 239000000674 adrenergic antagonist Substances 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 abstract 4
- 150000003180 prostaglandins Chemical class 0.000 abstract 4
- 208000010412 Glaucoma Diseases 0.000 abstract 2
- 206010030043 Ocular hypertension Diseases 0.000 abstract 2
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
ESTA INVENCION PROPORCIONA UN METODO PARA TRATAR LA HIPERTENSION OCULAS O EL GLAUCOMA EN EL OJO DE UN SUJETO. EL METODO COMPRENDE PONER EN CONTACTO LA SUPERFICIE DEL OJO CON UNA CANTIDAD EFECTIVA COMO REDUCTORA DE LA PRESION INTRAOCULAR DE UNA MEZCLA DE UN AGENTE BLOQUEANTE ADRENERGICO Y UNA PROSTAGLANDINA O UN DERIVADO DE ELLA EN UN VEHICULO OFTALMOLOGICAMENTE COMPATIBLE, DE FORMA QUE SE REDUZCA LA PRESION INTRAOCULAR DEL OJO Y LA MANTENGA REDUCIDA. ESTA INVENCION PRESENTA TAMBIEN UNA COMPOSICION PARA EL TRATAMIENTO DE LA HIPERTENSION OCULAR O DEL GLAUCOMA EN EL OJO DE UN SUJETO. LA COMPOSICION CONTIENE UNA CANTIDAD EFECTIVA COMO REDUCTORA DE LA PRESION INTRAOCULAR DE UNA MEZCLA DE UN AGENTE BLANQUEANTE ADRENERGICO Y UNA PROSTAGLANDINA O UN DERIVADO DE ESTA EN UN VEHICULO OFTALMOLOGICAMENTE COMPATIBLE.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3448487A | 1987-04-03 | 1987-04-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2042625T3 ES2042625T3 (es) | 1993-12-16 |
| ES2042625T5 true ES2042625T5 (es) | 2000-07-16 |
Family
ID=21876714
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES88104999T Expired - Lifetime ES2042625T5 (es) | 1987-04-03 | 1988-03-28 | Uso de una prostaglandina en combinacion con un agente bloqueante adrenergico para la reduccion de presion intraocular. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0286903B2 (es) |
| JP (1) | JP2726672B2 (es) |
| AT (1) | ATE76750T1 (es) |
| AU (1) | AU607981B2 (es) |
| CA (1) | CA1314220C (es) |
| DE (1) | DE3871596T3 (es) |
| ES (1) | ES2042625T5 (es) |
| GR (2) | GR3004794T3 (es) |
| HU (1) | HU211835A9 (es) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1334168C (en) * | 1988-04-26 | 1995-01-31 | Louis M. De Santis | Antiglaucoma compositions containing combinations of .alpha.-2 agonists and .beta. blockers |
| US5173507A (en) * | 1988-07-18 | 1992-12-22 | Alcon Laboratories, Inc. | Prostaglandin combinations in glaucoma therapy |
| US4994274A (en) * | 1989-07-27 | 1991-02-19 | Allergan, Inc. | Intraocular pressure reducing 11,15-diacyl prostaglandins and method of using |
| US5028624A (en) * | 1989-07-27 | 1991-07-02 | Allergan, Inc. | Intraocular pressure reducing 9,15-diacyl prostaglandins |
| CA2021316C (en) * | 1989-07-27 | 2000-10-24 | Ming Fai Chan | Intraocular pressure reducing 11-acyl prostaglandins |
| US5055467A (en) * | 1989-11-13 | 1991-10-08 | Allergan, Inc. | Pharmaceutical epinephrine-pilocarpine compounds |
| US5198545A (en) * | 1989-11-13 | 1993-03-30 | Allergan, Inc. | Pharmaceutical epinephrine-pilocarpine compounds and process of preparation thereof |
| US5011856A (en) * | 1990-03-12 | 1991-04-30 | Allergan, Inc. | Use of prostaglandin F3 α as an ocular hypotensive agent |
| CA2042934C (en) * | 1990-05-22 | 2002-04-23 | Ryuji Ueno | Treatment of ocular hypertension with an ocular synergistic combination |
| ES2084771T3 (es) * | 1990-05-22 | 1996-05-16 | R Tech Ueno Ltd | Tratamiento de la hipertension ocular con la ayuda de una combinacion sinergica. |
| DE69100171T2 (de) * | 1990-05-22 | 1993-10-28 | Ueno Seiyaku Oyo Kenkyujo Kk | Synergistische Kombination zur ophthalmischen Verwendung. |
| US5238961A (en) * | 1990-06-14 | 1993-08-24 | Allergan, Inc. | Pgf 1-alcohols and their use as ocular hypotensives |
| TW210287B (es) * | 1991-03-01 | 1993-08-01 | Kabushikaisha Ueno Seiyaku Oyo Kenkyujo | |
| DE69232150T2 (de) * | 1992-03-19 | 2002-03-07 | R-Tech Ueno, Ltd. | Behandlung von Augenhochdruck mit Betablockern und Prostansäurederivaten |
| JPH06107547A (ja) * | 1992-10-01 | 1994-04-19 | Aarutetsuku Ueno:Kk | 眼科用組成物 |
| WO1994008585A1 (en) * | 1992-10-13 | 1994-04-28 | Alcon Laboratories, Inc. | Combinations of prostaglandins and clonidine derivatives for the treatment of glaucoma |
| US5574066A (en) * | 1992-10-28 | 1996-11-12 | Allergan | Intraocular pressure reducing 15-acyl prostaglandins |
| SE9402816D0 (sv) * | 1994-08-24 | 1994-08-24 | Pharmacia Ab | Method and meams for drug administration |
| US5698733A (en) * | 1994-09-30 | 1997-12-16 | Alcon Laboratories, Inc. | Use of 9-deoxy prostaglandin derivatives to treat glaucoma |
| ATE311880T1 (de) * | 1998-01-23 | 2005-12-15 | Einar Stefansson | Carbonische anhydrase inhibitor zur steigerung des sauerstoffdrucks im sehnerv und retina |
| WO2002085372A1 (en) * | 2001-04-19 | 2002-10-31 | Teika Pharmaceutical Co., Ltd. | Medicines and medicinal kits |
| TWI298257B (en) * | 2001-05-31 | 2008-07-01 | Allergan Inc | Hypotensive lipid and timolol compositions and methods of using same |
| AU2007200821A1 (en) * | 2001-05-31 | 2007-03-15 | Allergan, Inc. | Hypotensive lipid and timolol compositions and methods of using same |
| TW200305424A (en) | 2002-01-29 | 2003-11-01 | Santen Pharmaceutical Co Ltd | Glaucoma-treating agent comprising bunazosin and prostaglandin |
| ATE546143T1 (de) * | 2002-08-29 | 2012-03-15 | Santen Pharmaceutical Co Ltd | Mittel zur behandlung von glaukom mit einem rho- kinase-hemmer und prostaglandinen |
| US7972612B2 (en) | 2002-11-18 | 2011-07-05 | Santen Pharmaceutical Co., Ltd. | Remedy for glaucoma comprising Rho kinase inhibitor and β-blocker |
| US7186744B2 (en) * | 2003-11-13 | 2007-03-06 | Allergan, Inc. | Prostamides for the treatment of glaucoma and related diseases |
| PT1905452E (pt) | 2005-07-12 | 2013-07-16 | Kowa Co | Agente para a prevenção ou tratamento do glaucoma |
| EP2127638A1 (en) | 2008-05-30 | 2009-12-02 | Santen Pharmaceutical Co., Ltd | Method and composition for treating ocular hypertension and glaucoma |
| EP2478906A4 (en) * | 2009-09-17 | 2013-02-20 | Senju Pharma Co | AQUEOUS OPHTHALMIC DROPS THAT CONTAIN LATANOPROST, AND A METHOD OF INHIBITING ADSORPTION OF LATANOPROST ON A RESIN |
| US9078854B2 (en) | 2010-07-29 | 2015-07-14 | Allergan, Inc. | Preservative free bimatoprost and timolol solutions |
| US9061034B2 (en) | 2010-07-29 | 2015-06-23 | Allergan, Inc. | Preservative free bimatoprost and timolol solutions |
| CN103338772A (zh) | 2011-02-04 | 2013-10-02 | 兴和株式会社 | 用于预防或治疗青光眼的药物疗法 |
| JP6193655B2 (ja) * | 2012-07-13 | 2017-09-06 | 参天製薬株式会社 | スルホンアミド化合物の組み合わせ |
| WO2018033854A1 (en) | 2016-08-15 | 2018-02-22 | Santen Pharmaceutical Co., Ltd. | Ophthalmic composition and a method for treating ocular hypertension and glaucoma |
| WO2019124487A1 (ja) | 2017-12-21 | 2019-06-27 | 参天製薬株式会社 | オミデネパグの組合せ |
| CA3086457A1 (en) | 2017-12-21 | 2019-06-27 | Santen Pharmaceutical Co., Ltd. | Medicament comprising combination of sepetaprost and rho-associated coiled-coil containing protein kinase inhibitor |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4454154A (en) * | 1981-06-23 | 1984-06-12 | American Hospital Supply Corporation | Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents |
| US4599353A (en) * | 1982-05-03 | 1986-07-08 | The Trustees Of Columbia University In The City Of New York | Use of eicosanoids and their derivatives for treatment of ocular hypertension and glaucoma |
| DE3300933A1 (de) * | 1983-01-13 | 1984-07-19 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verwendung von d,l- und d-carazolol als antiglaukommittel sowie arzneimittel, die diese stoffe enthalten |
| DE3785602T2 (de) * | 1986-03-13 | 1993-09-02 | Univ Columbia | Verwendung von a-, b- und c-prostaglandinen und deren derivaten zur behandlung von augen-hypertension und glaukom. |
-
1988
- 1988-03-28 DE DE3871596T patent/DE3871596T3/de not_active Expired - Lifetime
- 1988-03-28 AT AT88104999T patent/ATE76750T1/de not_active IP Right Cessation
- 1988-03-28 EP EP88104999A patent/EP0286903B2/en not_active Expired - Lifetime
- 1988-03-28 ES ES88104999T patent/ES2042625T5/es not_active Expired - Lifetime
- 1988-03-30 CA CA000562902A patent/CA1314220C/en not_active Expired - Lifetime
- 1988-03-30 AU AU13870/88A patent/AU607981B2/en not_active Expired
- 1988-04-01 JP JP63081167A patent/JP2726672B2/ja not_active Expired - Lifetime
-
1992
- 1992-06-04 GR GR920401036T patent/GR3004794T3/el unknown
-
1995
- 1995-06-28 HU HU95P/P00519P patent/HU211835A9/hu unknown
-
2000
- 2000-06-16 GR GR20000401411T patent/GR3033721T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE76750T1 (de) | 1992-06-15 |
| EP0286903A1 (en) | 1988-10-19 |
| JPS63313728A (ja) | 1988-12-21 |
| EP0286903B1 (en) | 1992-06-03 |
| DE3871596T2 (de) | 1993-01-21 |
| HU211835A9 (en) | 1995-12-28 |
| ES2042625T3 (es) | 1993-12-16 |
| GR3004794T3 (es) | 1993-04-28 |
| DE3871596D1 (de) | 1992-07-09 |
| AU607981B2 (en) | 1991-03-21 |
| DE3871596T3 (de) | 2000-09-07 |
| CA1314220C (en) | 1993-03-09 |
| JP2726672B2 (ja) | 1998-03-11 |
| EP0286903B2 (en) | 2000-03-29 |
| AU1387088A (en) | 1988-10-06 |
| GR3033721T3 (en) | 2000-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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