ES2042625T5 - Uso de una prostaglandina en combinacion con un agente bloqueante adrenergico para la reduccion de presion intraocular. - Google Patents
Uso de una prostaglandina en combinacion con un agente bloqueante adrenergico para la reduccion de presion intraocular.Info
- Publication number
- ES2042625T5 ES2042625T5 ES88104999T ES88104999T ES2042625T5 ES 2042625 T5 ES2042625 T5 ES 2042625T5 ES 88104999 T ES88104999 T ES 88104999T ES 88104999 T ES88104999 T ES 88104999T ES 2042625 T5 ES2042625 T5 ES 2042625T5
- Authority
- ES
- Spain
- Prior art keywords
- intraocular pressure
- blocking agent
- adrenergic blocking
- eye
- prostaglandine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000004410 intraocular pressure Effects 0.000 title abstract 5
- 239000000674 adrenergic antagonist Substances 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 abstract 4
- 150000003180 prostaglandins Chemical class 0.000 abstract 4
- 208000010412 Glaucoma Diseases 0.000 abstract 2
- 206010030043 Ocular hypertension Diseases 0.000 abstract 2
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
ESTA INVENCION PROPORCIONA UN METODO PARA TRATAR LA HIPERTENSION OCULAS O EL GLAUCOMA EN EL OJO DE UN SUJETO. EL METODO COMPRENDE PONER EN CONTACTO LA SUPERFICIE DEL OJO CON UNA CANTIDAD EFECTIVA COMO REDUCTORA DE LA PRESION INTRAOCULAR DE UNA MEZCLA DE UN AGENTE BLOQUEANTE ADRENERGICO Y UNA PROSTAGLANDINA O UN DERIVADO DE ELLA EN UN VEHICULO OFTALMOLOGICAMENTE COMPATIBLE, DE FORMA QUE SE REDUZCA LA PRESION INTRAOCULAR DEL OJO Y LA MANTENGA REDUCIDA. ESTA INVENCION PRESENTA TAMBIEN UNA COMPOSICION PARA EL TRATAMIENTO DE LA HIPERTENSION OCULAR O DEL GLAUCOMA EN EL OJO DE UN SUJETO. LA COMPOSICION CONTIENE UNA CANTIDAD EFECTIVA COMO REDUCTORA DE LA PRESION INTRAOCULAR DE UNA MEZCLA DE UN AGENTE BLANQUEANTE ADRENERGICO Y UNA PROSTAGLANDINA O UN DERIVADO DE ESTA EN UN VEHICULO OFTALMOLOGICAMENTE COMPATIBLE.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3448487A | 1987-04-03 | 1987-04-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2042625T3 ES2042625T3 (es) | 1993-12-16 |
| ES2042625T5 true ES2042625T5 (es) | 2000-07-16 |
Family
ID=21876714
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES88104999T Expired - Lifetime ES2042625T5 (es) | 1987-04-03 | 1988-03-28 | Uso de una prostaglandina en combinacion con un agente bloqueante adrenergico para la reduccion de presion intraocular. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0286903B2 (es) |
| JP (1) | JP2726672B2 (es) |
| AT (1) | ATE76750T1 (es) |
| AU (1) | AU607981B2 (es) |
| CA (1) | CA1314220C (es) |
| DE (1) | DE3871596T3 (es) |
| ES (1) | ES2042625T5 (es) |
| GR (2) | GR3004794T3 (es) |
| HU (1) | HU211835A9 (es) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1334168C (en) * | 1988-04-26 | 1995-01-31 | Louis M. De Santis | Antiglaucoma compositions containing combinations of .alpha.-2 agonists and .beta. blockers |
| US5173507A (en) * | 1988-07-18 | 1992-12-22 | Alcon Laboratories, Inc. | Prostaglandin combinations in glaucoma therapy |
| US4994274A (en) * | 1989-07-27 | 1991-02-19 | Allergan, Inc. | Intraocular pressure reducing 11,15-diacyl prostaglandins and method of using |
| US5028624A (en) * | 1989-07-27 | 1991-07-02 | Allergan, Inc. | Intraocular pressure reducing 9,15-diacyl prostaglandins |
| CA2021316C (en) * | 1989-07-27 | 2000-10-24 | Ming Fai Chan | Intraocular pressure reducing 11-acyl prostaglandins |
| US5198545A (en) * | 1989-11-13 | 1993-03-30 | Allergan, Inc. | Pharmaceutical epinephrine-pilocarpine compounds and process of preparation thereof |
| US5055467A (en) * | 1989-11-13 | 1991-10-08 | Allergan, Inc. | Pharmaceutical epinephrine-pilocarpine compounds |
| US5011856A (en) * | 1990-03-12 | 1991-04-30 | Allergan, Inc. | Use of prostaglandin F3 α as an ocular hypotensive agent |
| ATE117208T1 (de) * | 1990-05-22 | 1995-02-15 | R Tech Ueno Ltd | Behandlung von intraokularem druck mit einer ophthalmischen synergistischen kombination. |
| US5166175A (en) * | 1990-05-22 | 1992-11-24 | K.K. Ueno Seiyaku Oyo Kenkyujo | Treatment of ocular hypertension with a synergistic combination |
| ES2059058T3 (es) * | 1990-05-22 | 1994-11-01 | R Tech Ueno Ltd | Combinacion sinergica para uso oftalmico. |
| US5238961A (en) * | 1990-06-14 | 1993-08-24 | Allergan, Inc. | Pgf 1-alcohols and their use as ocular hypotensives |
| TW210287B (es) * | 1991-03-01 | 1993-08-01 | Kabushikaisha Ueno Seiyaku Oyo Kenkyujo | |
| ATE207360T1 (de) * | 1992-03-19 | 2001-11-15 | R Tech Ueno Ltd | Behandlung von augenhochdruck mit betablockern und prostansäurederivaten |
| JPH06107547A (ja) * | 1992-10-01 | 1994-04-19 | Aarutetsuku Ueno:Kk | 眼科用組成物 |
| DE69311361T2 (de) * | 1992-10-13 | 1998-01-08 | Alcon Lab Inc | Zusammensetzungen zur behandlung von glaukoma die prostaglandine und clonidinderivate enthalten |
| US5574066A (en) * | 1992-10-28 | 1996-11-12 | Allergan | Intraocular pressure reducing 15-acyl prostaglandins |
| SE9402816D0 (sv) * | 1994-08-24 | 1994-08-24 | Pharmacia Ab | Method and meams for drug administration |
| US5698733A (en) * | 1994-09-30 | 1997-12-16 | Alcon Laboratories, Inc. | Use of 9-deoxy prostaglandin derivatives to treat glaucoma |
| WO1999037292A2 (en) * | 1998-01-23 | 1999-07-29 | Merck Sharp & Dohme B.V. | Carbonic anhydrase inhibitor for increasing oxygen tension in the optic nerve and retina |
| BR0209063A (pt) * | 2001-04-19 | 2004-08-10 | Teika Pharmaceutical Co Ltd | Medicamentos e kits de uso medicinal |
| TWI298257B (en) * | 2001-05-31 | 2008-07-01 | Allergan Inc | Hypotensive lipid and timolol compositions and methods of using same |
| AU2007200821A1 (en) * | 2001-05-31 | 2007-03-15 | Allergan, Inc. | Hypotensive lipid and timolol compositions and methods of using same |
| TW200305424A (en) | 2002-01-29 | 2003-11-01 | Santen Pharmaceutical Co Ltd | Glaucoma-treating agent comprising bunazosin and prostaglandin |
| AU2003257588A1 (en) * | 2002-08-29 | 2004-03-19 | Santen Pharmaceutical Co., Ltd. | REMEDY FOR GLAUCOMA COMPRISING Rho KINASE INHIBITOR AND PROSTAGLANDINS |
| AU2003280812A1 (en) * | 2002-11-18 | 2004-06-15 | Santen Pharmaceutical Co., Ltd. | REMEDY FOR GLAUCOMA COMPRISING Rho KINASE INHIBITOR AND Beta-BLOCKER |
| US7186744B2 (en) * | 2003-11-13 | 2007-03-06 | Allergan, Inc. | Prostamides for the treatment of glaucoma and related diseases |
| PL1905452T3 (pl) | 2005-07-12 | 2013-11-29 | Kowa Co | Środek do zapobiegania lub leczenia jaskry |
| EP2127638A1 (en) | 2008-05-30 | 2009-12-02 | Santen Pharmaceutical Co., Ltd | Method and composition for treating ocular hypertension and glaucoma |
| CA2773597A1 (en) * | 2009-09-17 | 2011-03-24 | Senju Pharmaceutical Co., Ltd. | Latanoprost-containing aqueous eye drops and method for inhibiting adsorption of latanoprost to resin |
| RU2624534C2 (ru) | 2010-07-29 | 2017-07-04 | Аллерган, Инк. | Растворы биматопроста и тимолола, не содержащие консервантов |
| US9061034B2 (en) | 2010-07-29 | 2015-06-23 | Allergan, Inc. | Preservative free bimatoprost and timolol solutions |
| JPWO2012105674A1 (ja) | 2011-02-04 | 2014-07-03 | 興和株式会社 | 緑内障予防又は治療のための薬物療法 |
| CA3099517C (en) * | 2012-07-13 | 2022-04-26 | Santen Pharmaceutical Co., Ltd. | Combinations comprising a sulfonamide compound for the treatment of glaucoma or ocular hypertension |
| WO2018033854A1 (en) | 2016-08-15 | 2018-02-22 | Santen Pharmaceutical Co., Ltd. | Ophthalmic composition and a method for treating ocular hypertension and glaucoma |
| EP4338751B1 (en) | 2017-12-21 | 2025-09-03 | Santen Pharmaceutical Co., Ltd. | Combination of sepetaprost and netarsudil for use in the prophylaxis or treatment of glaucoma or ocular hypertension |
| EP3730143A4 (en) | 2017-12-21 | 2021-08-18 | Santen Pharmaceutical Co., Ltd. | OMIDENEPAG COMBINATION |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4454154A (en) * | 1981-06-23 | 1984-06-12 | American Hospital Supply Corporation | Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents |
| US4599353A (en) * | 1982-05-03 | 1986-07-08 | The Trustees Of Columbia University In The City Of New York | Use of eicosanoids and their derivatives for treatment of ocular hypertension and glaucoma |
| DE3300933A1 (de) * | 1983-01-13 | 1984-07-19 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verwendung von d,l- und d-carazolol als antiglaukommittel sowie arzneimittel, die diese stoffe enthalten |
| DE3785602T2 (de) * | 1986-03-13 | 1993-09-02 | Univ Columbia | Verwendung von a-, b- und c-prostaglandinen und deren derivaten zur behandlung von augen-hypertension und glaukom. |
-
1988
- 1988-03-28 EP EP88104999A patent/EP0286903B2/en not_active Expired - Lifetime
- 1988-03-28 DE DE3871596T patent/DE3871596T3/de not_active Expired - Lifetime
- 1988-03-28 ES ES88104999T patent/ES2042625T5/es not_active Expired - Lifetime
- 1988-03-28 AT AT88104999T patent/ATE76750T1/de not_active IP Right Cessation
- 1988-03-30 AU AU13870/88A patent/AU607981B2/en not_active Expired
- 1988-03-30 CA CA000562902A patent/CA1314220C/en not_active Expired - Lifetime
- 1988-04-01 JP JP63081167A patent/JP2726672B2/ja not_active Expired - Lifetime
-
1992
- 1992-06-04 GR GR920401036T patent/GR3004794T3/el unknown
-
1995
- 1995-06-28 HU HU95P/P00519P patent/HU211835A9/hu unknown
-
2000
- 2000-06-16 GR GR20000401411T patent/GR3033721T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GR3004794T3 (es) | 1993-04-28 |
| EP0286903A1 (en) | 1988-10-19 |
| AU607981B2 (en) | 1991-03-21 |
| HU211835A9 (en) | 1995-12-28 |
| EP0286903B1 (en) | 1992-06-03 |
| JP2726672B2 (ja) | 1998-03-11 |
| GR3033721T3 (en) | 2000-10-31 |
| DE3871596T3 (de) | 2000-09-07 |
| ATE76750T1 (de) | 1992-06-15 |
| EP0286903B2 (en) | 2000-03-29 |
| DE3871596D1 (de) | 1992-07-09 |
| ES2042625T3 (es) | 1993-12-16 |
| DE3871596T2 (de) | 1993-01-21 |
| JPS63313728A (ja) | 1988-12-21 |
| AU1387088A (en) | 1988-10-06 |
| CA1314220C (en) | 1993-03-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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