ES2043769T3 - Procedimiento para la preparacion de lactulosa a partir de lactosa mediante epimerizacion con aluminato sodico. - Google Patents
Procedimiento para la preparacion de lactulosa a partir de lactosa mediante epimerizacion con aluminato sodico.Info
- Publication number
- ES2043769T3 ES2043769T3 ES88119476T ES88119476T ES2043769T3 ES 2043769 T3 ES2043769 T3 ES 2043769T3 ES 88119476 T ES88119476 T ES 88119476T ES 88119476 T ES88119476 T ES 88119476T ES 2043769 T3 ES2043769 T3 ES 2043769T3
- Authority
- ES
- Spain
- Prior art keywords
- lactose
- sodium aluminate
- epimerization
- lactulose
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 title abstract 4
- 239000008101 lactose Substances 0.000 title abstract 4
- ANBBXQWFNXMHLD-UHFFFAOYSA-N aluminum;sodium;oxygen(2-) Chemical compound [O-2].[O-2].[Na+].[Al+3] ANBBXQWFNXMHLD-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 229910001388 sodium aluminate Inorganic materials 0.000 title abstract 2
- 238000006345 epimerization reaction Methods 0.000 title 1
- JCQLYHFGKNRPGE-FCVZTGTOSA-N lactulose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 JCQLYHFGKNRPGE-FCVZTGTOSA-N 0.000 title 1
- 229960000511 lactulose Drugs 0.000 title 1
- PFCRQPBOOFTZGQ-UHFFFAOYSA-N lactulose keto form Natural products OCC(=O)C(O)C(C(O)CO)OC1OC(CO)C(O)C(O)C1O PFCRQPBOOFTZGQ-UHFFFAOYSA-N 0.000 title 1
- 238000004090 dissolution Methods 0.000 abstract 3
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/04—Disaccharides
-
- C—CHEMISTRY; METALLURGY
- C13—SUGAR INDUSTRY
- C13K—SACCHARIDES OBTAINED FROM NATURAL SOURCES OR BY HYDROLYSIS OF NATURALLY OCCURRING DISACCHARIDES, OLIGOSACCHARIDES OR POLYSACCHARIDES
- C13K13/00—Sugars not otherwise provided for in this class
- C13K13/005—Lactulose
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
UN PROCESO PARA PREPARAR LACTUOSA DE LACTOSA EN EL CUAL, UNA MEZCLA DE LACTOSA ACUOSA SE HACE REACCIONAR CON UNA DISOLUCION DE ALUMINATO DE SODIO Y LA DISOLUCION OBTENIDA ES NEUTRALIZADA CONTINUAMENTE POR EL SUMINISTRO DE ESTA DISOLUCION Y UNA DISOLUCION DE ACIDO SULFURICO A UN REACTOR SIMULTANEAMENTE DE TAL MANERA QUE SE OBTIENE UN PH ENTRE 4.5 Y 8. POR OPERAR DE ESTA MANERA SE OBTIENE UN HIDROXIDO DE ALUMINIO QUE PUEDE SER FACILMENTE SEPARADO DE LA DISOLUCION LACTUOSA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8722847A IT1235866B (it) | 1987-12-01 | 1987-12-01 | Processo per la preparazione di lattolosio da lattosio mediante epimerizzazione con alluminato sodico |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2043769T3 true ES2043769T3 (es) | 1994-01-01 |
Family
ID=11201109
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES88119476T Expired - Lifetime ES2043769T3 (es) | 1987-12-01 | 1988-11-23 | Procedimiento para la preparacion de lactulosa a partir de lactosa mediante epimerizacion con aluminato sodico. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4957564A (es) |
| EP (1) | EP0320670B1 (es) |
| JP (1) | JPH0633304B2 (es) |
| KR (1) | KR890009958A (es) |
| AT (1) | ATE91305T1 (es) |
| CA (1) | CA1320721C (es) |
| DE (1) | DE3882211T2 (es) |
| ES (1) | ES2043769T3 (es) |
| IE (1) | IE62945B1 (es) |
| IT (1) | IT1235866B (es) |
| NZ (1) | NZ227126A (es) |
| ZA (1) | ZA888911B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL90388A (en) * | 1988-05-26 | 1993-08-18 | Duphar Int Res | Pharmaceutical compositions having anti- endotoxic activity containing a novel active fraction from lactulose syrup, and a method for its preparation |
| AU635352B2 (en) * | 1990-11-09 | 1993-03-18 | Applied Membrane Systems Pty Ltd | A method and apparatus for fractionation of sugar containing solution |
| IT1291589B1 (it) * | 1997-04-17 | 1999-01-11 | Inalco Spa | Processo per la preparazione di uno sciroppo di lattulosio mediante isomerizzazione di lattosio |
| JP6507318B2 (ja) | 2015-12-23 | 2019-04-24 | シージェイ チェイルジェダン コーポレーションCj Cheiljedang Corporation | D−プシコース3−エピメラーゼ及びその塩を含むd−プシコースを製造するための組成物、並びにこれを用いたd−プシコースの製造方法 |
| CN118955584B (zh) * | 2024-10-17 | 2024-12-20 | 广州市桐晖药业有限公司 | 一种高纯度乳果糖的制备工艺 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3546206A (en) * | 1967-09-20 | 1970-12-08 | Kraftco Corp | Method of making lactulose |
| US3822249A (en) * | 1971-04-19 | 1974-07-02 | Kraftco Corp | Method for manufacture of ketose sugars |
| JPS4919255A (es) * | 1972-06-05 | 1974-02-20 | ||
| IT1099668B (it) * | 1978-09-29 | 1985-09-28 | Molteni L & C Dei Filli Alitti | Processo per la produzione di lattulosio |
-
1987
- 1987-12-01 IT IT8722847A patent/IT1235866B/it active
-
1988
- 1988-11-17 US US07/272,445 patent/US4957564A/en not_active Expired - Fee Related
- 1988-11-23 DE DE88119476T patent/DE3882211T2/de not_active Expired - Fee Related
- 1988-11-23 EP EP88119476A patent/EP0320670B1/en not_active Expired - Lifetime
- 1988-11-23 AT AT88119476T patent/ATE91305T1/de not_active IP Right Cessation
- 1988-11-23 ES ES88119476T patent/ES2043769T3/es not_active Expired - Lifetime
- 1988-11-28 ZA ZA888911A patent/ZA888911B/xx unknown
- 1988-11-29 NZ NZ227126A patent/NZ227126A/xx unknown
- 1988-11-30 IE IE358188A patent/IE62945B1/en not_active IP Right Cessation
- 1988-11-30 CA CA000584566A patent/CA1320721C/en not_active Expired - Fee Related
- 1988-11-30 JP JP63301092A patent/JPH0633304B2/ja not_active Expired - Lifetime
- 1988-12-29 KR KR1019880015738A patent/KR890009958A/ko not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0633304B2 (ja) | 1994-05-02 |
| DE3882211T2 (de) | 1993-10-21 |
| ATE91305T1 (de) | 1993-07-15 |
| IE883581L (en) | 1989-06-01 |
| ZA888911B (en) | 1989-09-27 |
| IT1235866B (it) | 1992-11-23 |
| IT8722847A0 (it) | 1987-12-01 |
| EP0320670A1 (en) | 1989-06-21 |
| NZ227126A (en) | 1989-11-28 |
| IE62945B1 (en) | 1995-03-08 |
| CA1320721C (en) | 1993-07-27 |
| KR890009958A (ko) | 1989-08-05 |
| JPH01193281A (ja) | 1989-08-03 |
| EP0320670B1 (en) | 1993-07-07 |
| DE3882211D1 (de) | 1993-08-12 |
| US4957564A (en) | 1990-09-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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