ES2044246T3 - Medicamentos con liberacion controlada del producto activo. - Google Patents

Medicamentos con liberacion controlada del producto activo.

Info

Publication number
ES2044246T3
ES2044246T3 ES90101675T ES90101675T ES2044246T3 ES 2044246 T3 ES2044246 T3 ES 2044246T3 ES 90101675 T ES90101675 T ES 90101675T ES 90101675 T ES90101675 T ES 90101675T ES 2044246 T3 ES2044246 T3 ES 2044246T3
Authority
ES
Spain
Prior art keywords
active matter
medicines
controlled release
active product
pellets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90101675T
Other languages
English (en)
Inventor
Manfred Dipl-Ing Bucheler
Andreas Dr Ohm
Roland Dr Rupp
Josef Di Schmoll
Axel Dr Wollenschlager
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6373866&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2044246(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of ES2044246T3 publication Critical patent/ES2044246T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

EL INVENTO SE REFIERE A UN SISTEMA DE EMISION DE MATERIA ACTIVA EN FORMA DE PELLETS QUE CONTROLA LA LIBRE COLOCACION DE LA MATERIA ACTIVA Y AJUSTA LA EMISION NORMAL DE MATERIA ACTIVA MEDIANTE IMPULSOS, Y TAMBIEN LOS PERIODOS DE EMISION ACELERADA Y RETARDADA DE MATERIA ACTIVA. LOS PELLETS, CONSISTEN EN UN NUCLEO CONTENIENDO MATERIA ACTIVA, QUE SE RODEA POR UNA CUBIERTA CONTENIENDO POLIMERO Y UNA CAPA DE LACADO PERMEABLE AL AGUA Y NO INDIGESTA.
ES90101675T 1989-02-11 1990-01-28 Medicamentos con liberacion controlada del producto activo. Expired - Lifetime ES2044246T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3904093 1989-02-11

Publications (1)

Publication Number Publication Date
ES2044246T3 true ES2044246T3 (es) 1994-01-01

Family

ID=6373866

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90101675T Expired - Lifetime ES2044246T3 (es) 1989-02-11 1990-01-28 Medicamentos con liberacion controlada del producto activo.

Country Status (15)

Country Link
US (1) US5204121A (es)
EP (1) EP0386440B1 (es)
JP (1) JPH02300126A (es)
AT (1) ATE79029T1 (es)
AU (1) AU622273B2 (es)
CA (1) CA2009736A1 (es)
DE (1) DE59000232D1 (es)
DK (1) DK0386440T3 (es)
ES (1) ES2044246T3 (es)
GR (1) GR3005664T3 (es)
HU (1) HU206044B (es)
IE (1) IE900470L (es)
IL (1) IL93315A0 (es)
NZ (1) NZ232430A (es)
ZA (1) ZA90971B (es)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2558396B2 (ja) * 1990-06-28 1996-11-27 田辺製薬株式会社 放出制御型製剤
DE4319760A1 (de) * 1993-06-15 1994-12-22 Bayer Ag Ipsapiron Arzneimittelzubereitung
US5871776A (en) * 1995-01-31 1999-02-16 Mehta; Atul M. Controlled-release nifedipine
US5532014A (en) * 1995-08-16 1996-07-02 Townsend Engineering Company Method of linking a strand of uncased coextruded meat emulsion product
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
US5843504A (en) * 1996-10-15 1998-12-01 Townsend Engineering Company Method and apparatus for coagulating the outer surface of a sausage strand discharged from a sausage extruding machine
US5837379A (en) * 1997-01-31 1998-11-17 Andrx Pharmaceuticals, Inc. Once daily pharmaceutical tablet having a unitary core
US5922352A (en) * 1997-01-31 1999-07-13 Andrx Pharmaceuticals, Inc. Once daily calcium channel blocker tablet having a delayed release core
US5938520A (en) * 1997-04-10 1999-08-17 Townsend Engineering Company Conveyor for supporting sausage strands during coagulation cycle, and method of rinsing and drying the same
JPH1147581A (ja) * 1997-07-30 1999-02-23 Takasago Internatl Corp 徐放性カプセル及びその製造方法
US6485748B1 (en) 1997-12-12 2002-11-26 Andrx Pharmaceuticals, Inc. Once daily pharmaceutical tablet having a unitary core
BR9903490A (pt) * 1998-12-15 2000-09-26 Oscar Gold Processo para a preparação de composições farmacêuticas de liberação programada contendo nimodipine, que permitem a liberação gradual e a manuntenção da ação terapeutica
US6632451B2 (en) 1999-06-04 2003-10-14 Dexcel Pharma Technologies Ltd. Delayed total release two pulse gastrointestinal drug delivery system
KR100574213B1 (ko) * 2000-01-27 2006-04-27 다나베 세이야꾸 가부시키가이샤 서방성 제제 및 그의 제조 방법
ATE476968T1 (de) 2000-09-06 2010-08-15 Mitsubishi Tanabe Pharma Corp Granulat-zubereitungen zur oralen verabreichung
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
AUPR839001A0 (en) * 2001-10-19 2001-11-15 Eli Lilly And Company Dosage form, device and methods of treatment
MXPA04008100A (es) * 2002-02-21 2005-06-17 Biovail Lab Int Srl Formulaciones de liberacion modificada de al menos una forma de tramadol.
US8323692B2 (en) 2002-02-21 2012-12-04 Valeant International Bermuda Controlled release dosage forms
US6960346B2 (en) * 2002-05-09 2005-11-01 University Of Tennessee Research Foundation Vehicles for delivery of biologically active substances
AU2003231509A1 (en) 2002-05-16 2003-12-02 Shionogi And Co., Ltd. Compound exhibiting pgd 2 receptor antagonism
US20040121010A1 (en) * 2002-10-25 2004-06-24 Collegium Pharmaceutical, Inc. Pulsatile release compositions of milnacipran
US20060003004A1 (en) * 2002-10-25 2006-01-05 Collegium Pharmaceutical, Inc. Pulsatile release compositions of milnacipran
US8367111B2 (en) * 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
WO2004067039A1 (en) * 2003-01-28 2004-08-12 Collegium Pharmaceutical, Inc. Multiparticulate compositions of milnacipran for oral administration
US8747895B2 (en) * 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
NZ589750A (en) 2004-10-21 2012-07-27 Aptalis Pharmatech Inc Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
US20060105038A1 (en) * 2004-11-12 2006-05-18 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions prepared by coacervation
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
DE102005031577A1 (de) * 2005-07-06 2007-01-11 Bayer Healthcare Ag Pharmazeutische Darreichungsformen enthaltend eine Wirkstoffkombination von Nifedipin und/oder Nisoldipin und einem Angiotensin-II Antagonisten
US8193112B2 (en) * 2008-11-24 2012-06-05 University Of Lethbridge Catalysts for the polymerization of cyclic esters
DE102008059206A1 (de) 2008-11-27 2010-06-10 Bayer Schering Pharma Aktiengesellschaft Pharmazeutische Darreichungsform enthaltend Nifedipin oder Nisoldipin und einen Angiotensin-II Antagonisten und/oder ein Diuretikum
CN102958515A (zh) 2009-12-02 2013-03-06 阿普塔利斯制药有限公司 非索非那定微胶囊及含有非索非那定微胶囊的组合物
IN2014DN09045A (es) 2012-05-07 2015-05-22 Bayer Pharma AG
CN112592311B (zh) * 2021-01-03 2023-01-31 迪沙药业集团有限公司 一种硝苯地平a晶块状晶习及其控释片组合物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57171428A (en) * 1981-04-13 1982-10-22 Sankyo Co Ltd Preparation of coated solid preparation
GB8518301D0 (en) * 1985-07-19 1985-08-29 Fujisawa Pharmaceutical Co Hydrodynamically explosive systems
ES2022454B3 (es) * 1986-06-17 1991-12-01 Recordati Ind Chimica E Farm S P A Sistema terapeutico para la liberacion controlada de drogas.
US4800087A (en) * 1986-11-24 1989-01-24 Mehta Atul M Taste-masked pharmaceutical compositions
GB8703323D0 (en) 1987-02-13 1987-03-18 British Petroleum Co Plc Separation process
US4891223A (en) * 1987-09-03 1990-01-02 Air Products And Chemicals, Inc. Controlled release delivery coating formulation for bioactive substances
IL88083A (en) * 1987-11-06 1992-11-15 Tanabe Seiyaku Co Controlled release pharmaceutical dosage form and its preparation
JP2643222B2 (ja) * 1988-02-03 1997-08-20 エーザイ株式会社 多重層顆粒

Also Published As

Publication number Publication date
HUT57585A (en) 1991-12-30
EP0386440A1 (de) 1990-09-12
AU4927090A (en) 1990-11-01
NZ232430A (en) 1991-10-25
DK0386440T3 (da) 1992-09-14
EP0386440B1 (de) 1992-08-05
CA2009736A1 (en) 1990-08-11
GR3005664T3 (es) 1993-06-07
ATE79029T1 (de) 1992-08-15
IL93315A0 (en) 1990-11-29
ZA90971B (en) 1990-11-28
JPH02300126A (ja) 1990-12-12
HU900749D0 (en) 1990-04-28
DE59000232D1 (de) 1992-09-10
AU622273B2 (en) 1992-04-02
HU206044B (en) 1992-08-28
IE900470L (en) 1990-08-11
US5204121A (en) 1993-04-20

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