ES2075129T3 - Preparacion de gel que contiene estrogeno. - Google Patents

Preparacion de gel que contiene estrogeno.

Info

Publication number
ES2075129T3
ES2075129T3 ES90125109T ES90125109T ES2075129T3 ES 2075129 T3 ES2075129 T3 ES 2075129T3 ES 90125109 T ES90125109 T ES 90125109T ES 90125109 T ES90125109 T ES 90125109T ES 2075129 T3 ES2075129 T3 ES 2075129T3
Authority
ES
Spain
Prior art keywords
ingredient
preparation
gel containing
containing estrogen
intermolecular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90125109T
Other languages
English (en)
Inventor
Hitoshi Akemi
Takashi Kinoshita
Saburo Otsuka
Yoshifumi Hosaka
Kunio Tsukamoto
Yoshihisa Nakano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nitto Denko Corp
Aska Pharmaceutical Co Ltd
Original Assignee
Nitto Denko Corp
Teikoku Hormone Manufacturing Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nitto Denko Corp, Teikoku Hormone Manufacturing Co Ltd filed Critical Nitto Denko Corp
Application granted granted Critical
Publication of ES2075129T3 publication Critical patent/ES2075129T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)

Abstract

SE PRESENTA UN ESTROGENO QUE CONTIENE UNA PREPARACION DE GEL QUE CONSTA DE UN SUSTRATO QUE TIENE SOBRE UNA DE LAS CARAS DEL MISMO UNA CAPA DE GEL UNIDO DE FORMA INTERMOLECULAR FORMADO POR LA UNION INTERMOLECULAR DE UNA COMPOSICION QUE CONTIENE LOS INGREDIENTES SIGUIENTES (A) A (C) SIENDO LA PROPORCION DEL PESO DEL INGREDIENTE (B) AL INGREDIENTE (C) DE 1,0/0,25 A 1,0/2,0: (A) ESTROGENO; (B) UN POLIMERO DE ACRILATO; Y (C) UN INGREDIENTE LIQUIDO COMPATIBLE CON EL INGREDIENTE (B).
ES90125109T 1989-12-28 1990-12-21 Preparacion de gel que contiene estrogeno. Expired - Lifetime ES2075129T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP34463989 1989-12-28
JP23738390A JP3273430B2 (ja) 1989-12-28 1990-09-06 エストロゲン含有ゲル製剤

Publications (1)

Publication Number Publication Date
ES2075129T3 true ES2075129T3 (es) 1995-10-01

Family

ID=26533184

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90125109T Expired - Lifetime ES2075129T3 (es) 1989-12-28 1990-12-21 Preparacion de gel que contiene estrogeno.

Country Status (10)

Country Link
US (1) US5242951A (es)
EP (1) EP0435200B1 (es)
JP (1) JP3273430B2 (es)
KR (1) KR0173309B1 (es)
AT (1) ATE124872T1 (es)
CA (1) CA2033113C (es)
DE (1) DE69020875T2 (es)
DK (1) DK0435200T3 (es)
ES (1) ES2075129T3 (es)
GR (1) GR3017650T3 (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5762952A (en) * 1993-04-27 1998-06-09 Hercon Laboratories Corporation Transdermal delivery of active drugs
JP2539330B2 (ja) * 1993-05-11 1996-10-02 日東電工株式会社 医療用粘着剤及びこれを用いて形成された医療用外用材
DE4336299A1 (de) * 1993-10-25 1995-05-11 Arbo Robotron Medizin Technolo Gelkörper zur percutanen Verabreichung, insbesondere von Medikamenten
JP3576608B2 (ja) * 1994-11-15 2004-10-13 日東電工株式会社 貼付剤および貼付製剤
AU6032696A (en) * 1995-06-07 1996-12-30 Cygnus Therapeutic Systems Pressure sensitive acrylate adhesive composition cross-linke d with aluminum acetylacetonate and containing a drug having a reactive aromatic hydroxyl group
US5861431A (en) * 1995-06-07 1999-01-19 Iotek, Inc. Incontinence treatment
EP1806131A3 (en) 1996-07-22 2007-08-01 Renovo Limited Use of sex steroid function modulators to treat wounds and fibrotic disorders
CA2276339A1 (en) * 1997-02-21 1998-08-27 Michael J. Zajaczkowski Transdermal pressure sensitive adhesive drug delivery system and pressure sensitive adhesive used therein
US6239228B1 (en) 1997-02-21 2001-05-29 Adhesives Research, Inc. Pressure sensitive adhesive containing macromer having repeat hydrophilic moieties
US5951999A (en) * 1997-02-21 1999-09-14 Adhesives Research, Inc. Transdermal pressure sensitive adhesive drug delivery system
DE19834007C1 (de) * 1998-07-29 2000-02-24 Lohmann Therapie Syst Lts Estradiolhaltiges Pflaster zur transdermalen Applikation von Hormonen und seine Verwendung
AU1667701A (en) * 2000-02-10 2001-08-16 Rohm And Haas Company Bioadhesive composition
US6698162B2 (en) 2000-03-23 2004-03-02 Teikoku Pharma Usa, Inc. Methods of producing a terminally sterilized topical patch preparation
ATE355854T1 (de) 2000-08-03 2007-03-15 Antares Pharma Ipl Ag Neue zusammensetzung zur transdermalen und/oder transmukosalen wirkstoffanwendung mit geeignetem therapeutischen spiegel
US8980290B2 (en) 2000-08-03 2015-03-17 Antares Pharma Ipl Ag Transdermal compositions for anticholinergic agents
US7198801B2 (en) 2000-08-03 2007-04-03 Antares Pharma Ipl Ag Formulations for transdermal or transmucosal application
JP5027373B2 (ja) * 2002-08-09 2012-09-19 帝國製薬株式会社 エストラジオール含有貼付剤
US8124122B2 (en) 2002-08-09 2012-02-28 Teikoku Seiyaku Co., Ltd. Female hormone-containing patch
DK1670433T3 (da) 2003-10-10 2012-03-12 Ferring Bv Transdermal farmaceutisk formulering til mindskelse af hudrester
US7425340B2 (en) 2004-05-07 2008-09-16 Antares Pharma Ipl Ag Permeation enhancing compositions for anticholinergic agents
JP4745747B2 (ja) * 2004-08-12 2011-08-10 日東電工株式会社 フェンタニル含有貼付製剤
JP4824963B2 (ja) * 2004-08-12 2011-11-30 日東電工株式会社 貼付材及び貼付製剤
WO2006125642A1 (en) 2005-05-27 2006-11-30 Antares Pharma Ipl Ag Methods and apparatus for transdermal or transmucosal application of testosterone
CA2612380C (en) 2005-06-16 2017-06-06 Warner Chilcott Company, Inc. Estrogen compositions for vaginal administration
CN101232869B (zh) * 2005-06-16 2016-03-02 沃纳奇尔科特有限责任公司 局部给药的凝胶组合物
US20070004693A1 (en) * 2005-06-16 2007-01-04 Warner Chilcott Company Inc. Estrogen compositions for vaginal administration
CA2646667C (en) 2006-04-21 2014-03-11 Antares Pharma Ipl Ag Methods of treating hot flashes with formulations for transdermal or transmucosal application
CN107362131A (zh) * 2017-08-31 2017-11-21 北京海霞润月更年期综合症医学研究院 一种雌激素凝胶及制备方法
CN114344700B (zh) * 2022-01-18 2024-11-22 兰州大学 一种载有雌二醇微乳的可溶性微针及其制备方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3267083A (en) * 1963-06-07 1966-08-16 Union Carbide Corp Reprocessable crosslinked polymeric compositions
JPS51107389A (ja) * 1975-03-18 1976-09-22 Kojin Kk Horiakurirusanaruminiumuenno seizohoho
US4078060A (en) * 1976-05-10 1978-03-07 Richardson-Merrell Inc. Method of inducing an estrogenic response
SU1243627A3 (ru) * 1979-12-05 1986-07-07 Дзе Кендалл Компани (Фирма) Гелеобразующа композици
JPS572303A (en) * 1980-06-04 1982-01-07 Wako Pure Chem Ind Ltd Preparation of crosslinked alkali salt of polyacrylic acid
CH655656B (es) * 1982-10-07 1986-05-15
JPS60190723A (ja) * 1984-03-09 1985-09-28 Yamanouchi Pharmaceut Co Ltd 難溶性薬物の溶解速度向上方法
JPS61502760A (ja) * 1984-07-24 1986-11-27 キイ・フア−マシユ−テイカルズ・インコ−ポレイテツド 粘着性経皮投与層
JPS6160620A (ja) * 1984-09-03 1986-03-28 Teijin Ltd ピログルタミン酸エステル類を含有する医薬品組成物
DE3682165D1 (de) * 1985-11-08 1991-11-28 Nitto Denko Corp Verwendung von heftpflastern fuer die haut und perkutanen praeparaten.
CN1021196C (zh) * 1986-12-29 1993-06-16 新泽西州州立大学(鲁杰斯) 透皮雌激素/孕激素药剂单元、系统及方法
US4906475A (en) * 1988-02-16 1990-03-06 Paco Pharmaceutical Services Estradiol transdermal delivery system
WO1989007951A1 (en) * 1988-02-26 1989-09-08 Riker Laboratories, Incorporated Transdermal estradiol delivery system
US4994267A (en) * 1988-03-04 1991-02-19 Noven Pharmaceuticals, Inc. Transdermal acrylic multipolymer drug delivery system
US5200190A (en) * 1988-10-11 1993-04-06 Sekisui Kagaku Kogyo Kabushiki Kaisha Percutaneous pharmaceutical preparation
US5002986A (en) * 1989-02-28 1991-03-26 Hoechst Celanese Corporation Fluid absorbent compositions and process for their preparation

Also Published As

Publication number Publication date
EP0435200A2 (en) 1991-07-03
DE69020875D1 (de) 1995-08-17
DE69020875T2 (de) 1995-12-14
KR910011265A (ko) 1991-08-07
EP0435200B1 (en) 1995-07-12
GR3017650T3 (en) 1996-01-31
US5242951A (en) 1993-09-07
JP3273430B2 (ja) 2002-04-08
DK0435200T3 (da) 1995-11-20
KR0173309B1 (ko) 1999-02-01
ATE124872T1 (de) 1995-07-15
JPH03220121A (ja) 1991-09-27
CA2033113C (en) 1996-09-03
EP0435200A3 (en) 1991-09-11
CA2033113A1 (en) 1991-06-29

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