ES2045110T3 - Mejoras en o relacionadas con antagonistas de leucotrienos. - Google Patents

Mejoras en o relacionadas con antagonistas de leucotrienos.

Info

Publication number
ES2045110T3
ES2045110T3 ES88303178T ES88303178T ES2045110T3 ES 2045110 T3 ES2045110 T3 ES 2045110T3 ES 88303178 T ES88303178 T ES 88303178T ES 88303178 T ES88303178 T ES 88303178T ES 2045110 T3 ES2045110 T3 ES 2045110T3
Authority
ES
Spain
Prior art keywords
antagonists
leucotrene
leucotrene antagonists
derivatives
leukotrenees
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88303178T
Other languages
English (en)
Inventor
Robert Delane Dilliard
Doris Elfriede Mccullough
Francis Patrick Carr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of ES2045110T3 publication Critical patent/ES2045110T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/03—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

ESTA INVENCION PROPORCIONA DERIVADOS BENCENICOS QUE SON ANTAGONISTAS DE LEUCOTRIENO, FORMULACIONES QUE CONTIENEN ESTOS DERIVADOS EN EL TRATAMIENTO DE CONDICIONES CARACETRIZADAS POR UNA LIBERACION EXCESIVA DE LEUCOTRIENOS.
ES88303178T 1987-04-13 1988-04-08 Mejoras en o relacionadas con antagonistas de leucotrienos. Expired - Lifetime ES2045110T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/038,254 US4853398A (en) 1987-04-13 1987-04-13 Leukotriene antagonists and use thereas

Publications (1)

Publication Number Publication Date
ES2045110T3 true ES2045110T3 (es) 1994-01-16

Family

ID=21898886

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88303178T Expired - Lifetime ES2045110T3 (es) 1987-04-13 1988-04-08 Mejoras en o relacionadas con antagonistas de leucotrienos.

Country Status (22)

Country Link
US (1) US4853398A (es)
EP (1) EP0288189B1 (es)
JP (1) JPS63258831A (es)
KR (1) KR880012521A (es)
CN (1) CN1012433B (es)
AR (1) AR245705A1 (es)
AT (1) ATE82273T1 (es)
AU (1) AU607203B2 (es)
CA (1) CA1329613C (es)
DE (1) DE3875782T2 (es)
DK (1) DK188488A (es)
EG (1) EG19001A (es)
ES (1) ES2045110T3 (es)
GR (1) GR3006973T3 (es)
HU (1) HU202505B (es)
IE (1) IE61883B1 (es)
IL (1) IL85989A (es)
NZ (1) NZ224143A (es)
PH (1) PH25572A (es)
PT (1) PT87181B (es)
SU (1) SU1750420A3 (es)
ZA (1) ZA882421B (es)

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GB9007577D0 (en) * 1990-04-04 1990-05-30 Ici Plc Preparation of aromatic compounds
PT533268E (pt) * 1991-09-18 2002-02-28 Glaxo Group Ltd Derivados de benzanilida como antagonistas de 5-ht1d
PH30449A (en) * 1991-11-25 1997-05-28 Lilly Co Eli Substituted phenyl phenol leukotriene antagonists
US5865471A (en) 1993-08-05 1999-02-02 Kimberly-Clark Worldwide, Inc. Photo-erasable data processing forms
US6211383B1 (en) 1993-08-05 2001-04-03 Kimberly-Clark Worldwide, Inc. Nohr-McDonald elimination reaction
CA2120838A1 (en) 1993-08-05 1995-02-06 Ronald Sinclair Nohr Solid colored composition mutable by ultraviolet radiation
US5643356A (en) 1993-08-05 1997-07-01 Kimberly-Clark Corporation Ink for ink jet printers
US5645964A (en) 1993-08-05 1997-07-08 Kimberly-Clark Corporation Digital information recording media and method of using same
US6017661A (en) 1994-11-09 2000-01-25 Kimberly-Clark Corporation Temporary marking using photoerasable colorants
US5721287A (en) 1993-08-05 1998-02-24 Kimberly-Clark Worldwide, Inc. Method of mutating a colorant by irradiation
US6017471A (en) 1993-08-05 2000-01-25 Kimberly-Clark Worldwide, Inc. Colorants and colorant modifiers
US5773182A (en) 1993-08-05 1998-06-30 Kimberly-Clark Worldwide, Inc. Method of light stabilizing a colorant
US5733693A (en) 1993-08-05 1998-03-31 Kimberly-Clark Worldwide, Inc. Method for improving the readability of data processing forms
US5681380A (en) 1995-06-05 1997-10-28 Kimberly-Clark Worldwide, Inc. Ink for ink jet printers
US6242057B1 (en) 1994-06-30 2001-06-05 Kimberly-Clark Worldwide, Inc. Photoreactor composition and applications therefor
US5739175A (en) 1995-06-05 1998-04-14 Kimberly-Clark Worldwide, Inc. Photoreactor composition containing an arylketoalkene wavelength-specific sensitizer
US6071979A (en) 1994-06-30 2000-06-06 Kimberly-Clark Worldwide, Inc. Photoreactor composition method of generating a reactive species and applications therefor
US5685754A (en) 1994-06-30 1997-11-11 Kimberly-Clark Corporation Method of generating a reactive species and polymer coating applications therefor
US6008268A (en) 1994-10-21 1999-12-28 Kimberly-Clark Worldwide, Inc. Photoreactor composition, method of generating a reactive species, and applications therefor
US5786132A (en) 1995-06-05 1998-07-28 Kimberly-Clark Corporation Pre-dyes, mutable dye compositions, and methods of developing a color
US5811199A (en) 1995-06-05 1998-09-22 Kimberly-Clark Worldwide, Inc. Adhesive compositions containing a photoreactor composition
US5798015A (en) 1995-06-05 1998-08-25 Kimberly-Clark Worldwide, Inc. Method of laminating a structure with adhesive containing a photoreactor composition
MX9709250A (es) 1995-06-05 1998-03-31 Kimberly Clark Co Pre-tintes novedosos.
US5849411A (en) 1995-06-05 1998-12-15 Kimberly-Clark Worldwide, Inc. Polymer film, nonwoven web and fibers containing a photoreactor composition
US5747550A (en) 1995-06-05 1998-05-05 Kimberly-Clark Worldwide, Inc. Method of generating a reactive species and polymerizing an unsaturated polymerizable material
MX9710016A (es) 1995-06-28 1998-07-31 Kimberly Clark Co Colorantes novedosos y modificadores de colorante.
US5782963A (en) 1996-03-29 1998-07-21 Kimberly-Clark Worldwide, Inc. Colorant stabilizers
US5855655A (en) 1996-03-29 1999-01-05 Kimberly-Clark Worldwide, Inc. Colorant stabilizers
EP0854896B1 (en) 1995-11-28 2002-04-03 Kimberly-Clark Worldwide, Inc. Light-stabilized dyestuff compositions
US6099628A (en) 1996-03-29 2000-08-08 Kimberly-Clark Worldwide, Inc. Colorant stabilizers
US5891229A (en) 1996-03-29 1999-04-06 Kimberly-Clark Worldwide, Inc. Colorant stabilizers
US6524379B2 (en) 1997-08-15 2003-02-25 Kimberly-Clark Worldwide, Inc. Colorants, colorant stabilizers, ink compositions, and improved methods of making the same
CN1090950C (zh) * 1998-03-26 2002-09-18 苏贻利 一种治疗痣的中西合成药及其制备方法
EP1062285A2 (en) 1998-06-03 2000-12-27 Kimberly-Clark Worldwide, Inc. Neonanoplasts and microemulsion technology for inks and ink jet printing
PL338379A1 (en) 1998-06-03 2000-10-23 Kimberly Clark Co Novel photoinitiators and their application
JP2002520470A (ja) 1998-07-20 2002-07-09 キンバリー クラーク ワールドワイド インコーポレイテッド 改良されたインクジェットインク組成物
CA2353685A1 (en) 1998-09-28 2000-04-06 Kimberly-Clark Worldwide, Inc. Chelates comprising chinoid groups as photoinitiators
AU2853000A (en) 1999-01-19 2000-08-01 Kimberly-Clark Worldwide, Inc. Novel colorants, colorant stabilizers, ink compositions, and improved methods ofmaking the same
US6331056B1 (en) 1999-02-25 2001-12-18 Kimberly-Clark Worldwide, Inc. Printing apparatus and applications therefor
US6294698B1 (en) 1999-04-16 2001-09-25 Kimberly-Clark Worldwide, Inc. Photoinitiators and applications therefor
US6368395B1 (en) 1999-05-24 2002-04-09 Kimberly-Clark Worldwide, Inc. Subphthalocyanine colorants, ink compositions, and method of making the same
WO2006044602A2 (en) * 2004-10-18 2006-04-27 Merck & Co., Inc. Diphenyl substituted alkanes as flap inhiibitors
ES2333979T3 (es) 2004-11-22 2010-03-03 Eli Lilly And Company Potenciadores de los receptores del glutamato.
ATE543810T1 (de) * 2006-09-01 2012-02-15 Merck Sharp & Dohme Hemmer des 5-lipoxygenase aktivierenden proteins (flap)

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU469247A3 (ru) * 1972-01-14 1975-04-30 Майлз Лабораториз Инк (Фирма) Способ получени производных хромона
ATE14579T1 (de) * 1979-03-20 1985-08-15 Fisons Plc Pharmazeutische heterocyclische verbindungen, verfahren zu ihrer herstellung und sie enthaltende zusammensetzungen.
ES494769A0 (es) * 1979-09-05 1981-07-16 Glaxo Group Ltd Un procedimiento para la pre-paracion de fenoxialcoxifenil- derivados.
EP0056172B1 (en) * 1981-01-09 1985-04-03 FISONS plc Phenoxy- and thiophenoxy compounds, methods for their preparation and pharmaceutical formulations containing them
DE3265715D1 (en) * 1981-03-24 1985-10-03 Fisons Plc Anti srs-a carboxylic acid derivatives, processes for their production and pharmaceutical formulations containing them
US4474788A (en) * 1981-11-12 1984-10-02 Fisons Plc Anti-SRSA quinoline carboxylic acid derivatives
US4567201A (en) * 1981-11-25 1986-01-28 Takeda Chemical Industries, Ltd. Diphenoxypropane derivatives and compositions of antiasthmatic and antiinflammatory agents thereof
US4499299A (en) * 1981-12-30 1985-02-12 Ici Americas Inc. Pharmaceutically active phenylcarboxylic acid derivatives
US4661505A (en) * 1982-11-03 1987-04-28 Eli Lilly And Company Leukotriene antagonists
ZA844519B (en) * 1983-06-24 1985-02-27 Hoffmann La Roche Dihydrobenzopyran derivatives
US5105017A (en) * 1983-07-18 1992-04-14 Eli Lilly And Company Leukotriene antagonist intermediates
US4644071A (en) * 1984-07-11 1987-02-17 G. D. Searle & Co. Aralkoxy and aryloxyalkoxy kojic acid derivatives
US4617407A (en) * 1984-08-30 1986-10-14 Merck Frosst Canada, Inc. Leukotriene antagonists
US4567279A (en) * 1984-12-13 1986-01-28 Usv Pharmaceutical Corp. Diarylhydroxy alkanones and alkenones antiallergy agents
US4628115A (en) * 1985-03-25 1986-12-09 Hoffmann-La Roche Inc. Substituted 4-acetyl-3-hydroxyphenoxy alkanoic acids
US4874777A (en) * 1987-04-10 1989-10-17 Eli Lilly And Company Leukotriene antagonists
US4820722A (en) * 1987-08-14 1989-04-11 Eli Lilly And Company Disubstituted tetrazoles and their use as leukotriene antagonists

Also Published As

Publication number Publication date
CA1329613C (en) 1994-05-17
DK188488D0 (da) 1988-04-07
EP0288189A1 (en) 1988-10-26
ZA882421B (en) 1989-12-27
DK188488A (da) 1988-10-14
EG19001A (en) 1994-04-30
AU1433388A (en) 1988-10-13
AR245705A1 (es) 1994-02-28
PT87181A (pt) 1988-05-01
SU1750420A3 (ru) 1992-07-23
IL85989A (en) 1993-08-18
ATE82273T1 (de) 1992-11-15
JPS63258831A (ja) 1988-10-26
US4853398A (en) 1989-08-01
EP0288189B1 (en) 1992-11-11
IE881061L (en) 1988-10-13
HU202505B (en) 1991-03-28
NZ224143A (en) 1990-02-26
CN1012433B (zh) 1991-04-24
IE61883B1 (en) 1994-11-30
KR880012521A (ko) 1988-11-28
DE3875782D1 (de) 1992-12-17
CN88101940A (zh) 1988-11-09
GR3006973T3 (es) 1993-06-30
DE3875782T2 (de) 1993-04-01
HUT53358A (en) 1990-10-28
PH25572A (en) 1991-08-08
AU607203B2 (en) 1991-02-28
PT87181B (pt) 1992-07-31

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