ES2066546T3 - Composicion farmaceutica para inhibir la resorcion osea. - Google Patents

Composicion farmaceutica para inhibir la resorcion osea.

Info

Publication number
ES2066546T3
ES2066546T3 ES92121256T ES92121256T ES2066546T3 ES 2066546 T3 ES2066546 T3 ES 2066546T3 ES 92121256 T ES92121256 T ES 92121256T ES 92121256 T ES92121256 T ES 92121256T ES 2066546 T3 ES2066546 T3 ES 2066546T3
Authority
ES
Spain
Prior art keywords
resorption
group
osea
inhibit
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92121256T
Other languages
English (en)
Inventor
Mizuho Inazu
Ryoichi Satoh
Tsutomu Inoue
Hiroshi Kitagawa
Masakazu Katoh
Heinrich Dr Englert
Denis Dr Carniato
Hans-Jochen Dr Lang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis KK
Original Assignee
Hoechst Japan Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Japan Ltd filed Critical Hoechst Japan Ltd
Application granted granted Critical
Publication of ES2066546T3 publication Critical patent/ES2066546T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

COMPOSICIONES FARMACEUTICAS PARA INHIBIR LA RESORCION OSEA QUE COMPRENDE UN PORTADOR FARMACEUTICO Y UNA CANTIDAD TERAPEUTICAMENTE EFECTIVA DE UN DERIVADO DE BENZOPIRANO REPRESENTADO POR LA FORMULA GENERAL (I) EN DONDE EL ENLACE DE LINEAS SEPARADAS REPRESENTA UN ENLACE DOBLE OPCIONAL, R1 REPRESENTA UN ATOMO DE HIDROGENO O UN GRUPO HIDROXILO, R2 REPRESENTA UN GRUPO CIANO, UN GRUPO FENILSULFONILO O UN GRUPO METOXILO SUSTITUIDO POR HALOGENO Y R3 REPRESENTA UN GRUPO QUE TIENE LA FORMULA O PUESTO QUE INHIBEN LA RESORCION OSEA, SON UTILES PARA EL TRATAMIENTO Y PREVENCION DE ENFERMEDADES ASOCIADAS AL METABOLISMO DE LOS HUESOS.
ES92121256T 1991-12-16 1992-12-14 Composicion farmaceutica para inhibir la resorcion osea. Expired - Lifetime ES2066546T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP33176791 1991-12-16
JP23914492A JP3502403B2 (ja) 1991-12-16 1992-09-08 骨吸収抑制剤

Publications (1)

Publication Number Publication Date
ES2066546T3 true ES2066546T3 (es) 1995-03-01

Family

ID=26534099

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92121256T Expired - Lifetime ES2066546T3 (es) 1991-12-16 1992-12-14 Composicion farmaceutica para inhibir la resorcion osea.

Country Status (10)

Country Link
US (1) US5317029A (es)
EP (1) EP0547545B1 (es)
JP (1) JP3502403B2 (es)
KR (1) KR100257496B1 (es)
AT (1) ATE114465T1 (es)
CA (1) CA2085421A1 (es)
DE (1) DE69200757T2 (es)
DK (1) DK0547545T3 (es)
ES (1) ES2066546T3 (es)
TW (1) TW223016B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5280040A (en) * 1993-03-11 1994-01-18 Zymogenetics, Inc. Methods for reducing bone loss using centchroman derivatives
US5837702A (en) * 1993-10-07 1998-11-17 Bristol-Myers Squibb Co. 4-arylamino-benzopyran and related compounds
US5389646A (en) * 1993-12-30 1995-02-14 Zymogenetics, Inc. Methods for treatment and prevention of bone loss using 2,3-benzopyrans
GB9408577D0 (en) * 1994-04-29 1994-06-22 Fujisawa Pharmaceutical Co New compound
US5629429A (en) * 1995-06-07 1997-05-13 Bristol-Myers Squibb Company Process for preparing 4-arylamino-benzopyran and related compounds
US5612323A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phosphinic ester substituted benzopyran derivatives
US5869478A (en) * 1995-06-07 1999-02-09 Bristol-Myers Squibb Company Sulfonamido substituted benzopyran derivatives
US5612370A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phenylglycine and phenylalaninen amido benzopyran derivatives
EP0783888A1 (en) * 1995-12-26 1997-07-16 Sankyo Company Limited Use of troglitazone and related thiazolidinediones in the manufacture of a medicament for the treatment and prophylaxis of osteoporosis
US20080108086A1 (en) * 1999-06-02 2008-05-08 Cantor Thomas L Parathyroid hormone antagonists and uses thereof
WO2004028444A2 (en) * 1999-06-02 2004-04-08 Scantibodies Laboratory, Inc. Parathyroid hormone antagonists and uses thereof
KR100389127B1 (ko) * 2000-10-09 2003-06-25 동부한농화학 주식회사 벤조피라닐 헤테로고리 유도체, 그의 제조방법 및 그를포함하는 약학적 조성물
TWI396543B (zh) * 2005-05-12 2013-05-21 Sankyo Co 取代丙烯醯胺衍生物及含有它之醫藥組成物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZM7682A1 (en) * 1981-09-25 1983-05-23 Beecham Group Plc Active compounds
DE3364145D1 (de) * 1982-04-08 1986-07-24 Beecham Group Plc Antihypertensive benzopyranols
DE3368629D1 (en) * 1982-04-28 1987-02-05 Beecham Group Plc Novel chromenes and chromans
JPS58219183A (ja) * 1982-04-28 1983-12-20 ビ−チヤム・グル−プ・ピ−エルシ− 新規なクロマノ−ル，その製法及びそれらを含む製薬組成物
GB8513369D0 (en) * 1985-05-28 1985-07-03 Beecham Group Plc Treatment
DE3703227A1 (de) * 1987-02-04 1988-08-18 Hoechst Ag Substituierte 3,4-dihydro-2h-benzopyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen
DE3823533A1 (de) * 1988-07-12 1990-02-08 Beiersdorf Ag Substituierte 4-heterocyclyl-2h-benzo(b)pyrane, verfahren und 4-hydroxy-3-brom-, 3,4-oxiranyl-3,4-dehydro-2h-benzo(b)pyrane als zwischenprodukte zu ihrer herstellung, sowie sie enthaltende pharmazeutsche praeparate

Also Published As

Publication number Publication date
DE69200757T2 (de) 1995-05-11
KR100257496B1 (ko) 2000-08-01
JP3502403B2 (ja) 2004-03-02
EP0547545A1 (en) 1993-06-23
DE69200757D1 (de) 1995-01-12
JPH05221860A (ja) 1993-08-31
ATE114465T1 (de) 1994-12-15
TW223016B (es) 1994-05-01
KR930012036A (ko) 1993-07-20
US5317029A (en) 1994-05-31
DK0547545T3 (da) 1995-05-15
EP0547545B1 (en) 1994-11-30
CA2085421A1 (en) 1993-06-17

Similar Documents

Publication Publication Date Title
DK0639577T3 (da) Phosphonooxymethyl- eller methylthiomethylestere af taxanderivater som antitumormidler
ES2066546T3 (es) Composicion farmaceutica para inhibir la resorcion osea.
ES2071020T3 (es) Derivados de n-fenilpirazol.
PY0101600A (es) Compuesto oral antibacterial antiplaca
ES2096639T3 (es) Derivados de benzofurano, benzotiofeno, indol o indolizina, su procedimiento de preparacion, asi como las composiciones que los contienen.
MX9300498A (es) Derivados de n-sulfonil-2-oxo-indol, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.
ES2045110T3 (es) Mejoras en o relacionadas con antagonistas de leucotrienos.
MX9305769A (es) Nuevos derivados de analogos del taxol, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.
UA26427A (uk) Похідhі ксаhтиhу у вигляді суміші ізомерів або іhдивідуальhих ізомерів, що мають властивість аhтагоhіста адеhозиhу
ES2059207T3 (es) Procedimiento para la preparacion de derivados del taxano, nuevos derivados obtenidos y composiciones farmaceuticas que les contienen.
ES2195970T3 (es) L-ribavirina y usos de la misma.
ES2062943B1 (es) Nuevos derivados de la (2-metil-3-piridil) cianometilpiperazinas.
ES2059335T3 (es) Derivados de pirido(3,2,1-ij)-1,3,4-benzoxadiazina, procedimiento para su obtencion, preparados farmaceuticos correspondientes y productos intermedios utilizables en el procedimiento.
ES2129485T3 (es) Derivados de acidos guanidinoalquil-1,1-bisfosfonicos, procedimiento para su preparacion y su utilizacion.
DK0717041T3 (da) Krystallinske paclitaxel-hydrater
MX9100607A (es) Compuesto triciclico novedoso o sales del mismo,metodo para producir el mismo y agente antimicrobiano que lo contiene
ES2181366T3 (es) Derivados de piperidina que tienen efectos sobre sistemas relacionados con serotonina.
ES2138613T3 (es) Derivado de espirooxatiolano-quinuclidina para el tratamiento del sindrome de sjoegren.
MD1560F2 (en) Cyclic compounds, pharmaceutical compositions on base thereof and methods of treatment of infections or diseases provoked by retroviruses.
IT1264988B1 (it) Composizioni cosmetiche e dermatologiche per la protezione da radiazioni uv contenenti derivati dallo stilbene
PT90743A (pt) Processo para a preparacao de derivados de hirudina com accao retardada e de composicoes farmaceuticas que os contem
ES2045348T3 (es) Metodo para preparar derivados de lactamimida para el tratamiento o la prevencion de paludismo farmaco-resistente.
ES2123499T3 (es) Metodos y composiciones para tratamiento de infecciones virales.
ES2070002T3 (es) Composiciones terapeuticas a base de derivados de 1,2-ditiol-3-tiona.
ES2010513B3 (es) Nuevos derivados de 6- o 7-metilenoandrosta-1,4-dieno3,17-diona y procedimiento para su preparacion.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 547545

Country of ref document: ES