ES2045219T3 - Procedimiento para la preparacion de derivados del acido fenoxicarboxilico. - Google Patents

Procedimiento para la preparacion de derivados del acido fenoxicarboxilico.

Info

Publication number
ES2045219T3
ES2045219T3 ES89103897T ES89103897T ES2045219T3 ES 2045219 T3 ES2045219 T3 ES 2045219T3 ES 89103897 T ES89103897 T ES 89103897T ES 89103897 T ES89103897 T ES 89103897T ES 2045219 T3 ES2045219 T3 ES 2045219T3
Authority
ES
Spain
Prior art keywords
atom
derivatives
acid
phenoxicarboxilico
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89103897T
Other languages
English (en)
Inventor
Mitsuo Ohashi
Katsuya Awano
Toshio Tanaka
Tetsuya Kimura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyorin Pharmaceutical Co Ltd
Original Assignee
Kyorin Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Pharmaceutical Co Ltd filed Critical Kyorin Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2045219T3 publication Critical patent/ES2045219T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/24—Sulfones; Sulfoxides having sulfone or sulfoxide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

DERIVADOS DEL ACIDO FENOXIALQUILCARBOXILICO DE LA FORMULA(I), DONDE R1 INDICA UN ATOMO DE H, GRUPO METILO O GRUPO ETILO, N ES UN NUMERO ENTERO ENTRE 2 Y 5, Y N ES UN ENTERO ENTRE 3 Y 8, X1 Y X2 ES INDEPENDIENTEMENTE UN ATOMO DE S, ATOMO DE H, GRUPO SULFINILO O GRUPO SULFONILO, SE PREVEE QUE X1 Y X2 NO SON A LA VEZ UN ATOMO DE O; SUS SALES ALCALINAS E HIDRATOS DE ESTAS SON UTILES COMO AGENTES ANTIALERGICOS.
ES89103897T 1988-03-07 1989-03-06 Procedimiento para la preparacion de derivados del acido fenoxicarboxilico. Expired - Lifetime ES2045219T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5337488 1988-03-07

Publications (1)

Publication Number Publication Date
ES2045219T3 true ES2045219T3 (es) 1994-01-16

Family

ID=12941043

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89103897T Expired - Lifetime ES2045219T3 (es) 1988-03-07 1989-03-06 Procedimiento para la preparacion de derivados del acido fenoxicarboxilico.

Country Status (9)

Country Link
US (2) US4985585A (es)
EP (1) EP0332109B1 (es)
KR (1) KR960007602B1 (es)
CN (1) CN1022407C (es)
AU (1) AU617439B2 (es)
CA (1) CA1331763C (es)
DE (1) DE68900485D1 (es)
ES (1) ES2045219T3 (es)
HU (2) HU208524B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4985585A (en) 1988-03-07 1991-01-15 Kyorin Pharmaceutical Co., Ltd. Phenoxyalkylcarboxylic acid derivatives and process for their preparations
US5290812A (en) * 1991-01-18 1994-03-01 Kyorin Pharmaceutical Co., Ltd. Phenoxyalkylcarboxylic acid derivatives and process of preparing the same
KR100784653B1 (ko) 2000-01-26 2007-12-12 교린 세이야꾸 가부시키 가이샤 점안제
US7060854B2 (en) * 2003-06-24 2006-06-13 Medicinova, Inc. Process for making polymorphic form A of 4-[6-acetyl-3-[3-(4-acetyl-3-hydroxy-2-propylphenylthio)propoxy]-2-propylphenoxy]butyric acid
US7064146B2 (en) * 2003-06-24 2006-06-20 Medicinova, Inc. Pharmaceutical compositions of isolated orthorhombic crystalline 4-[6-acetyl-3-[3-(4-acetyl-3-hydroxy-2-propylphenylthio)propoxy]-2-propylphenoxy]butyric acid and methods of use
MXPA06012564A (es) * 2004-04-27 2007-01-31 Medicinova Inc Derivados de acido fenoxialquilcarboxilico en el tratamiento de enfermedades inflamatorias.
CN101022796B (zh) 2004-07-14 2013-02-27 炎症研究中心有限公司 抑制肿瘤转移的方法
US8962687B2 (en) 2012-12-05 2015-02-24 Medicinova, Inc. Method of treating liver disorders
US8835499B2 (en) 2011-12-08 2014-09-16 Medicinova, Inc. Method of treating non-alcoholic fatty liver disease and steatohepatitis
BR112016001400B1 (pt) 2013-07-25 2023-02-28 Medicinova, Inc Uso de ácidos fenoxialquilcarboxílicos para preparação de medicamentos para a redução de níveis sanguíneos de triglicerídeos, colesterol total e lipoproteínas de baixa densidade
US20150321989A1 (en) * 2014-05-08 2015-11-12 Medicinova, Inc. Method of treating idiopathic pulmonary fibrosis
US9346754B2 (en) 2014-05-08 2016-05-24 Medicinova, Inc. Method of treating advanced non-alcoholic steatohepatitis
JP6469727B2 (ja) 2014-06-02 2019-02-13 メディシノバ・インコーポレイテッドＭｅｄｉｃｉＮｏｖａ， Ｉｎｃ． 線維症の抑制又は治療方法
CA3217719A1 (en) 2021-05-28 2022-12-01 Kazuko Matsuda Phenoxyalkylcarboxylic acid derivatives and their use in lowering triglyceride levels

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2058785B (en) * 1979-09-05 1983-05-25 Glaxo Group Ltd Phenol derivatives
EP0056172B1 (en) * 1981-01-09 1985-04-03 FISONS plc Phenoxy- and thiophenoxy compounds, methods for their preparation and pharmaceutical formulations containing them
US4507498A (en) * 1982-04-09 1985-03-26 Hoffmann-La Roche Inc. Phenoxycarboxylic acids
IL69691A (en) * 1982-09-23 1988-01-31 Merck Frosst Canada Inc Leukotriene antagonists,their preparation and pharmaceutical compositions containing them
AU7450087A (en) * 1987-05-22 1988-11-24 Lunam, M.A. Pillow
JPH0819041B2 (ja) 1987-09-10 1996-02-28 杏林製薬株式会社 フェノキシアルキルカルボン酸誘導体及びその製造法
US4985585A (en) 1988-03-07 1991-01-15 Kyorin Pharmaceutical Co., Ltd. Phenoxyalkylcarboxylic acid derivatives and process for their preparations
US5290812A (en) 1991-01-18 1994-03-01 Kyorin Pharmaceutical Co., Ltd. Phenoxyalkylcarboxylic acid derivatives and process of preparing the same

Also Published As

Publication number Publication date
KR960007602B1 (ko) 1996-06-07
HU912411D0 (en) 1991-12-30
AU3088489A (en) 1989-09-07
CN1036560A (zh) 1989-10-25
US4985585A (en) 1991-01-15
EP0332109A1 (en) 1989-09-13
HU208524B (en) 1993-11-29
KR890014435A (ko) 1989-10-23
CN1022407C (zh) 1993-10-13
DE68900485D1 (de) 1992-01-16
HU204030B (en) 1991-11-28
EP0332109B1 (en) 1991-12-04
HUT50112A (en) 1989-12-28
CA1331763C (en) 1994-08-30
AU617439B2 (en) 1991-11-28
USRE38921E1 (en) 2005-12-13

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