ES2046325T3 - Un equipo de ensayo para niveles de adipsina para uso en el diagnostico de anormalidades geneticas o metabolicas. - Google Patents

Un equipo de ensayo para niveles de adipsina para uso en el diagnostico de anormalidades geneticas o metabolicas.

Info

Publication number
ES2046325T3
ES2046325T3 ES198888810211T ES88810211T ES2046325T3 ES 2046325 T3 ES2046325 T3 ES 2046325T3 ES 198888810211 T ES198888810211 T ES 198888810211T ES 88810211 T ES88810211 T ES 88810211T ES 2046325 T3 ES2046325 T3 ES 2046325T3
Authority
ES
Spain
Prior art keywords
genetic
adipsine
diagnosis
levels
adipsin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888810211T
Other languages
English (en)
Inventor
S. Flier Jeffrey
Bruce M. Spiegelmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dana Farber Cancer Institute Inc
Beth Israel Deaconess Medical Center Inc
Original Assignee
Dana Farber Cancer Institute Inc
Beth Israel Deaconess Medical Center Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dana Farber Cancer Institute Inc, Beth Israel Deaconess Medical Center Inc filed Critical Dana Farber Cancer Institute Inc
Application granted granted Critical
Publication of ES2046325T3 publication Critical patent/ES2046325T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/04Endocrine or metabolic disorders
    • G01N2800/042Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/04Endocrine or metabolic disorders
    • G01N2800/044Hyperlipemia or hypolipemia, e.g. dyslipidaemia, obesity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

METODO PARA DISTINGUIR ENTRE PERSONAS QUE TIENEN METABOLISMOS NORMALES, Y GANAN PESO DEBIDO A SOBREALIMENTACION, DE LAS PERSONAS QUE TIENEN PROPENSION A GANAR PESO DEBIDO A UNA ANORMALIDAD GENETICA, DETECTANDO EL NIVEL DE LA PROTEINA ADIPSINA EN LA SANGRE O EN EL NIVEL DE DNA DE ADIPSINA EN LOS LEUCOCITOS. METODO PARA TRATAR LA ANORMALIDAD DE GANANCIA DE PESO GENETICA MEDIANTE ADMINISTRACION DE CANTIDADES TERAPEUTICAS DE ADIPSINA.
ES198888810211T 1987-04-02 1988-03-30 Un equipo de ensayo para niveles de adipsina para uso en el diagnostico de anormalidades geneticas o metabolicas. Expired - Lifetime ES2046325T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3420387A 1987-04-02 1987-04-02

Publications (1)

Publication Number Publication Date
ES2046325T3 true ES2046325T3 (es) 1994-02-01

Family

ID=21874944

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888810211T Expired - Lifetime ES2046325T3 (es) 1987-04-02 1988-03-30 Un equipo de ensayo para niveles de adipsina para uso en el diagnostico de anormalidades geneticas o metabolicas.

Country Status (13)

Country Link
EP (2) EP0382720B1 (es)
JP (1) JPH02503229A (es)
AT (1) ATE80465T1 (es)
AU (1) AU606946B2 (es)
DE (1) DE3874543T2 (es)
DK (1) DK675388A (es)
ES (1) ES2046325T3 (es)
FI (1) FI894592L (es)
GR (1) GR3005716T3 (es)
IL (1) IL85897A0 (es)
NO (1) NO885360L (es)
WO (1) WO1988007681A1 (es)
ZA (1) ZA882288B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991018924A1 (en) * 1990-06-01 1991-12-12 W. Alton Jones Cell Science Center Mammalian adipogenic factors
CA2503390A1 (en) * 2002-11-01 2004-05-21 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
WO2015138309A1 (en) 2014-03-13 2015-09-17 Dana-Farber Cancer Institute, Inc. Compositions and methods for regulating pancreatic beta cell function using adipsin
DE102014107380A1 (de) * 2014-05-26 2015-11-26 Eberhard Karls Universität Tübingen Medizinische Fakultät Verfahren zur Diagnose einer durch den alternativen Weg des Komplementsystems vermittelten Krankheit oder eines Risikos hierfür

Also Published As

Publication number Publication date
DE3874543D1 (de) 1992-10-15
GR3005716T3 (es) 1993-06-07
DK675388D0 (da) 1988-12-02
WO1988007681A1 (en) 1988-10-06
EP0287509B1 (en) 1992-09-16
ZA882288B (en) 1988-12-28
EP0382720B1 (en) 1992-09-09
EP0287509A1 (en) 1988-10-19
AU1591388A (en) 1988-11-02
EP0382720A1 (en) 1990-08-22
AU606946B2 (en) 1991-02-21
NO885360L (no) 1989-02-01
JPH02503229A (ja) 1990-10-04
FI894592A7 (fi) 1989-09-28
IL85897A0 (en) 1988-09-30
NO885360D0 (no) 1988-12-01
FI894592A0 (fi) 1989-09-28
DK675388A (da) 1988-12-02
DE3874543T2 (de) 1993-02-04
FI894592L (fi) 1989-09-28
ATE80465T1 (de) 1992-09-15
EP0382720A4 (en) 1991-01-02

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