ES2093607T3 - Rna bicatenario para la correccion de anomalias en complejos inmunes circulantes y en la funcion de los monocitos. - Google Patents

Rna bicatenario para la correccion de anomalias en complejos inmunes circulantes y en la funcion de los monocitos.

Info

Publication number
ES2093607T3
ES2093607T3 ES88306418T ES88306418T ES2093607T3 ES 2093607 T3 ES2093607 T3 ES 2093607T3 ES 88306418 T ES88306418 T ES 88306418T ES 88306418 T ES88306418 T ES 88306418T ES 2093607 T3 ES2093607 T3 ES 2093607T3
Authority
ES
Spain
Prior art keywords
rna
immune
bicatenary
anomalies
monocytes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88306418T
Other languages
English (en)
Inventor
William A Carter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HEM Pharmaceuticals Corp
Original Assignee
HEM Pharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HEM Pharmaceuticals Corp filed Critical HEM Pharmaceuticals Corp
Application granted granted Critical
Publication of ES2093607T3 publication Critical patent/ES2093607T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)

Abstract

EL USO DE UN RNA DOBLEMENTE INMOVILIZADO PARA LA FABRICACION DE UN MEDICAMENTO PARA TRATAR UN DESORDEN INFLAMATORIO CARACTERIZADO POR ELEVADOS NIVELES DE CIRCULACION DE COMPLEJOS INMUNES EN LA SANGRE DEL PACIENTE.
ES88306418T 1987-07-17 1988-07-13 Rna bicatenario para la correccion de anomalias en complejos inmunes circulantes y en la funcion de los monocitos. Expired - Lifetime ES2093607T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7461687A 1987-07-17 1987-07-17
US12457787A 1987-11-24 1987-11-24

Publications (1)

Publication Number Publication Date
ES2093607T3 true ES2093607T3 (es) 1997-01-01

Family

ID=26755855

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88306418T Expired - Lifetime ES2093607T3 (es) 1987-07-17 1988-07-13 Rna bicatenario para la correccion de anomalias en complejos inmunes circulantes y en la funcion de los monocitos.

Country Status (18)

Country Link
EP (1) EP0300680B1 (es)
JP (1) JP2601520B2 (es)
KR (1) KR0131880B1 (es)
CN (1) CN1035050A (es)
AT (1) ATE142500T1 (es)
AU (2) AU1820588A (es)
CA (1) CA1326999C (es)
DE (1) DE3855527T2 (es)
DK (1) DK399288A (es)
ES (1) ES2093607T3 (es)
FI (1) FI883352A7 (es)
HU (1) HUT47432A (es)
IE (1) IE76914B1 (es)
IL (1) IL86862A (es)
NO (1) NO175023C (es)
NZ (1) NZ225310A (es)
OA (1) OA08890A (es)
PT (1) PT87996B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963532A (en) * 1987-11-25 1990-10-16 Hem Research, Inc. dsRNA-based prevention of viral escape
EP0473576A4 (en) * 1989-05-19 1993-03-10 Hem Research, Inc. Short therapeutic dsrna of defined structure
WO1991005560A1 (en) * 1989-10-11 1991-05-02 Hem Research, Inc. PROTECTION FROM SHOCK SUBSEQUENT TO INJURY BY DOUBLE-STRANDED RNAs
ZA908037B (en) * 1989-10-11 1991-09-25 Hem Res Inc Protection from shock subsequent to injury by double-standed rnas
US5132292A (en) * 1990-05-25 1992-07-21 Hem Research, Inc. Treatment of viral hepatitis
GB9108085D0 (en) * 1991-04-16 1991-06-05 Scras Complexes of polyadenylic acid with polyuridylic acid
AU2268892A (en) * 1991-07-16 1993-02-23 Hem Pharmaceuticals Corp. Modulation and diagnosis of cytokine dysfunctions
FR2768344B1 (fr) * 1997-08-26 2001-02-16 Scras Produit comprenant au moins un arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique dans le traitement d'une maladie virale
AR013269A1 (es) * 1997-08-04 2000-12-13 Scras Producto que contiene por lo menos un rna de doble filamento combinado con por lo menos un agente anti-viral, para la utilizacion terapeutica en eltratamiento de una enfermedad viral, en especial de la hepatitis viral
FR2768345B1 (fr) * 1997-09-17 2001-05-04 Scras Produit comprenant au moins un arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique dans le traitement d'une maladie virale, notamment d'une hepatite virale
FR2766715B1 (fr) * 1997-08-04 2001-02-16 Scras Produit comprenant au moins de l'arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique simultanee, separee ou etalee dans le temps, dans le traitement d'une maladie virale
US6506559B1 (en) 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
AUPP249298A0 (en) 1998-03-20 1998-04-23 Ag-Gene Australia Limited Synthetic genes and genetic constructs comprising same I
CN101818145A (zh) 1998-03-20 2010-09-01 联邦科学和工业研究组织 控制基因表达
CA2361201A1 (en) 1999-01-28 2000-08-03 Medical College Of Georgia Research Institute, Inc. Composition and method for in vivo and in vitro attenuation of gene expression using double stranded rna
US6423885B1 (en) 1999-08-13 2002-07-23 Commonwealth Scientific And Industrial Research Organization (Csiro) Methods for obtaining modified phenotypes in plant cells
CA2369944A1 (en) 2001-01-31 2002-07-31 Nucleonics Inc. Use of post-transcriptional gene silencing for identifying nucleic acid sequences that modulate the function of a cell
EP1838338A2 (en) * 2004-12-29 2007-10-03 Mannkind Corporation Methods to trigger, maintain and manipulate immune responses by targeted administration of biological response modifiers into lymphoid organs
EP3319587B1 (en) * 2015-11-17 2019-08-21 Bioncotech Therapeutics, S.L Novel pharmaceutical composition comprising particles comprising a complex of a double-stranded polyribonucleotide and a polyalkyleneimine
CN105434341B (zh) * 2015-12-22 2018-07-10 肇庆大华农生物药品有限公司 一种兽用聚腺尿苷酸注射液及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4024222A (en) * 1973-10-30 1977-05-17 The Johns Hopkins University Nucleic acid complexes
US4140761A (en) * 1977-04-11 1979-02-20 The United States Of America As Represented By The Department Of Health, Education & Welfare Modification of hepatitis B virus infection in chronic carriers of hepatitis B surface antigen
EP0113162B1 (en) * 1982-09-16 1989-07-19 Hem Research, Inc. Anti-proliferative action of dsnras on tumor cells
CA1326450C (en) * 1985-08-26 1994-01-25 William A. Carter Modulation of aids virus-related events by double stranded rnas (dsrnas)

Also Published As

Publication number Publication date
FI883352L (fi) 1989-01-18
HUT47432A (en) 1989-03-28
KR890001580A (ko) 1989-03-27
IE76914B1 (en) 1997-11-05
FI883352A0 (fi) 1988-07-14
NO175023C (no) 1994-08-17
NZ225310A (en) 1991-05-28
NO175023B (no) 1994-05-09
FI883352A7 (fi) 1989-01-18
DE3855527T2 (de) 1997-04-03
EP0300680A3 (en) 1991-06-19
ATE142500T1 (de) 1996-09-15
AU1761195A (en) 1995-06-29
IE881894L (en) 1989-01-17
PT87996A (pt) 1989-06-30
EP0300680B1 (en) 1996-09-11
KR0131880B1 (ko) 1998-04-17
DE3855527D1 (de) 1996-10-17
CN1035050A (zh) 1989-08-30
CA1326999C (en) 1994-02-15
PT87996B (pt) 1995-03-31
JP2601520B2 (ja) 1997-04-16
DK399288D0 (da) 1988-07-15
DK399288A (da) 1989-01-18
NO882853D0 (no) 1988-06-28
AU1820588A (en) 1989-01-19
NO882853L (no) 1989-01-18
IL86862A0 (en) 1988-11-30
JPS6490126A (en) 1989-04-06
OA08890A (en) 1989-10-31
IL86862A (en) 1993-05-13
EP0300680A2 (en) 1989-01-25

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