ES2093607T3 - Rna bicatenario para la correccion de anomalias en complejos inmunes circulantes y en la funcion de los monocitos. - Google Patents

Rna bicatenario para la correccion de anomalias en complejos inmunes circulantes y en la funcion de los monocitos.

Info

Publication number
ES2093607T3
ES2093607T3 ES88306418T ES88306418T ES2093607T3 ES 2093607 T3 ES2093607 T3 ES 2093607T3 ES 88306418 T ES88306418 T ES 88306418T ES 88306418 T ES88306418 T ES 88306418T ES 2093607 T3 ES2093607 T3 ES 2093607T3
Authority
ES
Spain
Prior art keywords
rna
immune
bicatenary
anomalies
monocytes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88306418T
Other languages
English (en)
Inventor
William A Carter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HEM Pharmaceuticals Corp
Original Assignee
HEM Pharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HEM Pharmaceuticals Corp filed Critical HEM Pharmaceuticals Corp
Application granted granted Critical
Publication of ES2093607T3 publication Critical patent/ES2093607T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)

Abstract

EL USO DE UN RNA DOBLEMENTE INMOVILIZADO PARA LA FABRICACION DE UN MEDICAMENTO PARA TRATAR UN DESORDEN INFLAMATORIO CARACTERIZADO POR ELEVADOS NIVELES DE CIRCULACION DE COMPLEJOS INMUNES EN LA SANGRE DEL PACIENTE.
ES88306418T 1987-07-17 1988-07-13 Rna bicatenario para la correccion de anomalias en complejos inmunes circulantes y en la funcion de los monocitos. Expired - Lifetime ES2093607T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7461687A 1987-07-17 1987-07-17
US12457787A 1987-11-24 1987-11-24

Publications (1)

Publication Number Publication Date
ES2093607T3 true ES2093607T3 (es) 1997-01-01

Family

ID=26755855

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88306418T Expired - Lifetime ES2093607T3 (es) 1987-07-17 1988-07-13 Rna bicatenario para la correccion de anomalias en complejos inmunes circulantes y en la funcion de los monocitos.

Country Status (18)

Country Link
EP (1) EP0300680B1 (es)
JP (1) JP2601520B2 (es)
KR (1) KR0131880B1 (es)
CN (1) CN1035050A (es)
AT (1) ATE142500T1 (es)
AU (2) AU1820588A (es)
CA (1) CA1326999C (es)
DE (1) DE3855527T2 (es)
DK (1) DK399288A (es)
ES (1) ES2093607T3 (es)
FI (1) FI883352A7 (es)
HU (1) HUT47432A (es)
IE (1) IE76914B1 (es)
IL (1) IL86862A (es)
NO (1) NO175023C (es)
NZ (1) NZ225310A (es)
OA (1) OA08890A (es)
PT (1) PT87996B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963532A (en) * 1987-11-25 1990-10-16 Hem Research, Inc. dsRNA-based prevention of viral escape
EP0473576A4 (en) * 1989-05-19 1993-03-10 Hem Research, Inc. Short therapeutic dsrna of defined structure
DE69029738T2 (de) * 1989-10-11 1997-08-14 Hem Pharma Corp Schutz gegen schock infolge einer schädigung durch doppelsträngige rna's
ZA908037B (en) * 1989-10-11 1991-09-25 Hem Res Inc Protection from shock subsequent to injury by double-standed rnas
US5132292A (en) * 1990-05-25 1992-07-21 Hem Research, Inc. Treatment of viral hepatitis
GB9108085D0 (en) * 1991-04-16 1991-06-05 Scras Complexes of polyadenylic acid with polyuridylic acid
WO1993001717A1 (en) * 1991-07-16 1993-02-04 Hem Pharmaceuticals Corp. Modulation and diagnosis of cytokine dysfunctions
FR2768344B1 (fr) * 1997-08-26 2001-02-16 Scras Produit comprenant au moins un arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique dans le traitement d'une maladie virale
FR2766715B1 (fr) * 1997-08-04 2001-02-16 Scras Produit comprenant au moins de l'arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique simultanee, separee ou etalee dans le temps, dans le traitement d'une maladie virale
TW589189B (en) 1997-08-04 2004-06-01 Scras Kit containing at least one double-stranded RNA combined with at least one anti-viral agent for therapeutic use in the treatment of a viral disease, notably of viral hepatitis
FR2768345B1 (fr) * 1997-09-17 2001-05-04 Scras Produit comprenant au moins un arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique dans le traitement d'une maladie virale, notamment d'une hepatite virale
US6506559B1 (en) 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
BRPI9908967B1 (pt) 1998-03-20 2017-05-30 Benitec Australia Ltd processos para reprimir, retardar ou de outro modo reduzir a expressão de um gene alvo em uma célula de planta
AUPP249298A0 (en) 1998-03-20 1998-04-23 Ag-Gene Australia Limited Synthetic genes and genetic constructs comprising same I
WO2000044914A1 (en) 1999-01-28 2000-08-03 Medical College Of Georgia Research Institute, Inc. Composition and method for in vivo and in vitro attenuation of gene expression using double stranded rna
US6423885B1 (en) 1999-08-13 2002-07-23 Commonwealth Scientific And Industrial Research Organization (Csiro) Methods for obtaining modified phenotypes in plant cells
CA2369944A1 (en) 2001-01-31 2002-07-31 Nucleonics Inc. Use of post-transcriptional gene silencing for identifying nucleic acid sequences that modulate the function of a cell
EP2351576A1 (en) * 2004-12-29 2011-08-03 Mannkind Corporation Methods to trigger, maintain and manipulate immune responses by targeted administration of biological response modifiers into lymphoid organs
KR102317281B1 (ko) * 2015-11-17 2021-10-25 하이라이트 테라퓨틱스 에스.엘. 이본쇄 폴리리보뉴클레오타이드 및 폴리알킬렌이민의 복합체를 포함하는 입자를 포함하는 신규 약제학적 조성물
CN105434341B (zh) * 2015-12-22 2018-07-10 肇庆大华农生物药品有限公司 一种兽用聚腺尿苷酸注射液及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4024222A (en) * 1973-10-30 1977-05-17 The Johns Hopkins University Nucleic acid complexes
US4140761A (en) * 1977-04-11 1979-02-20 The United States Of America As Represented By The Department Of Health, Education & Welfare Modification of hepatitis B virus infection in chronic carriers of hepatitis B surface antigen
DE3380200D1 (en) * 1982-09-16 1989-08-24 William Alvin Carter Anti-proliferative action of dsnras on tumor cells
CA1326450C (en) * 1985-08-26 1994-01-25 William A. Carter Modulation of aids virus-related events by double stranded rnas (dsrnas)

Also Published As

Publication number Publication date
EP0300680B1 (en) 1996-09-11
NO175023C (no) 1994-08-17
PT87996A (pt) 1989-06-30
HUT47432A (en) 1989-03-28
DE3855527T2 (de) 1997-04-03
JPS6490126A (en) 1989-04-06
OA08890A (en) 1989-10-31
CN1035050A (zh) 1989-08-30
AU1761195A (en) 1995-06-29
KR0131880B1 (ko) 1998-04-17
AU1820588A (en) 1989-01-19
NO882853L (no) 1989-01-18
IE76914B1 (en) 1997-11-05
FI883352A0 (fi) 1988-07-14
DK399288D0 (da) 1988-07-15
CA1326999C (en) 1994-02-15
FI883352L (fi) 1989-01-18
JP2601520B2 (ja) 1997-04-16
KR890001580A (ko) 1989-03-27
FI883352A7 (fi) 1989-01-18
NZ225310A (en) 1991-05-28
EP0300680A2 (en) 1989-01-25
IL86862A0 (en) 1988-11-30
EP0300680A3 (en) 1991-06-19
DK399288A (da) 1989-01-18
PT87996B (pt) 1995-03-31
ATE142500T1 (de) 1996-09-15
DE3855527D1 (de) 1996-10-17
IL86862A (en) 1993-05-13
NO882853D0 (no) 1988-06-28
IE881894L (en) 1989-01-17
NO175023B (no) 1994-05-09

Similar Documents

Publication Publication Date Title
ES2170141T3 (es) 4-aminoderivados del acido micofenolico con actividad inmunosupresora.
ES2086623T3 (es) Azaheterociclilmetil-cromanos como principios activos para el tratamiento de enfermedades del sistema nervioso central.
ES546011A0 (es) Aparato para supervisar los cambios de actividad de reduccion-oxidacion in vivo.
ES2063011T3 (es) Agentes antibacteriales de quinolonas y naftiridinas que contienen un alfa-aminoacido en la cadena lateral del 7-sustituyente.
FI875533L (fi) Insulinpreparat foer non-parenteral dosering.
NO821832L (no) Fremgangsmaate for fremstilling av allergenholdige kapsler
DE3875425D1 (de) Vasokinetisch wirkende polyungesaettigte saeuren und sie enthaltende pharmazeutische oder kosmetische zubereitungen.
ES2168359T3 (es) Acido micofenolico 6-sustituido y derivados con actividad inmunosupresora.
ES2000196A4 (es) Utilizacion de dipropilenglicolmonometileter como sustancia en productos moldeadores para el cabello.
DE3855527D1 (de) Doppelsträngige RNS zur Korrektur von Abnormalitäten von zirkulierenden Immunkomplexen und der Monozytenfunktion
AR243605A1 (es) Un metodo para obtener protoporfirina ix del cultivo de microalgas eucarioticas del genero clamidomonas.
IT1183181B (it) Derivati del 3-metil-imidazo(4,5-c)pirazolo con attivita' terapeutica e procedimento per la loropreparazione
IT8548055A1 (it) Composizioni farmaceutiche per la terapia di sindromi cerebrali involutive e del decadimento mentale
ES2107414T3 (es) Utilizacion de interferon-beta humano para la estimulacion de la eritropoyesis.
ES2063747T3 (es) Nuevos benzotiofenos que tienen actividad antialergica, asi como nuevos benzotiofenos y otros benzotiofenos seleccionados que tienen actividad para el tratamiento del sindrome de malestar respiratorio agudo.
ES544664A0 (es) Procedimiento para el diagnostico in vitro del sexo
DK137589A (da) Salicylsyreholdigt middel til behandling af hudsygdomme
ES2080954T3 (es) Uso de beta-aletina en cultivos de celulas y en terapia.
ES2169124T3 (es) Acido 4-aminomicofenolico 6-sustituido y derivados con actividad inmunosupresora.
FI810637A7 (fi) Lääkeaineen imeytymistä edistävien apuaineiden käyttö - laktaamiantibiootteja sisältävissä valmisteissa.
ATE78164T1 (de) Verwendung von metalloporphyrin zur umkehr des toxischen effekts der tumortherapie.
Sosnowski et al. Treatment of murine transitional cell carcinoma with intralesional interleukin 2 and murine interferon gamma
ES2057528T3 (es) Pdgf-a, pdgf-aa, pdgf-ab, procedimientos de preparacion y medicamentos que los contienen.
ATE130194T1 (de) Subkutane verabreichung des humanen choriongonadotropins.
SU540063A1 (ru) Гидроцилиндр одностороннего действи

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 300680

Country of ref document: ES