ES2046500T3 - Derivado de la histamina, su preparacion y su aplicacion en terapeutica. - Google Patents

Derivado de la histamina, su preparacion y su aplicacion en terapeutica.

Info

Publication number
ES2046500T3
ES2046500T3 ES198989401143T ES89401143T ES2046500T3 ES 2046500 T3 ES2046500 T3 ES 2046500T3 ES 198989401143 T ES198989401143 T ES 198989401143T ES 89401143 T ES89401143 T ES 89401143T ES 2046500 T3 ES2046500 T3 ES 2046500T3
Authority
ES
Spain
Prior art keywords
histamine
therapeutics
derived
preparation
application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198989401143T
Other languages
English (en)
Inventor
Jean-Michel Res. Du Chateau Courcelles Arrang
Monique Garbarg
Walter Schunack
Jean-Charles Schwartz
Ralph Ortwin Lipp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioprojet SC
Institut National de la Santé et de la Recherche Médicale
Original Assignee
Bioprojet SC
Institut National de la Santé et de la Recherche Médicale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioprojet SC, Institut National de la Santé et de la Recherche Médicale filed Critical Bioprojet SC
Application granted granted Critical
Publication of ES2046500T3 publication Critical patent/ES2046500T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A ALFA - BETA - DIMETILHISTAMINA, DE FORMULA (I) BAJO FORMA RACEMICA, DE ISOMERO OPTICO O DE MEZCLA DIASTEREOISOMERICA, ASI COMO SUS SALES DE ADICION A ACIDOS FARMACEUTICAMENTE ACEPTABLES. PUEDE PREPARARSE A PARTIR DE UN 2 AMINO 3 - (1H - IMIDAZOL - 4 - YL) - BUTIRATO DE ALQUILO O DE UN (1H - IMIDAZOL - 4 - YL) - CARBOXILATO DE ALQUILO. MEDICAMENTO.
ES198989401143T 1988-04-22 1989-04-21 Derivado de la histamina, su preparacion y su aplicacion en terapeutica. Expired - Lifetime ES2046500T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8805399A FR2630328B1 (fr) 1988-04-22 1988-04-22 Derive de l'histamine, sa preparation et son application en therapeutique

Publications (1)

Publication Number Publication Date
ES2046500T3 true ES2046500T3 (es) 1994-02-01

Family

ID=9365603

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198989401143T Expired - Lifetime ES2046500T3 (es) 1988-04-22 1989-04-21 Derivado de la histamina, su preparacion y su aplicacion en terapeutica.

Country Status (7)

Country Link
US (1) US5034539A (es)
EP (1) EP0338939B1 (es)
JP (1) JPH0655728B2 (es)
AT (1) ATE85051T1 (es)
DE (1) DE68904586T2 (es)
ES (1) ES2046500T3 (es)
FR (1) FR2630328B1 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2661909B1 (fr) * 1990-05-09 1997-08-14 Inst Nat Sante Rech Med Nouveaux composes agonistes du recepteur h3 de l'histamine a usage therapeutique, compositions pharmaceutiques agissant comme agonistes dudit recepteur et procede de preparation.
NZ238688A (en) * 1990-06-28 1992-05-26 Smithkline Beecham Corp Substituted histidines: pharmaceutical compositions, preparation and uses thereof
US5162541A (en) * 1990-09-10 1992-11-10 Schering Corporation Transfer hydrogenolysis of alkylheteroaryl halo-containing compounds
AU662588B2 (en) * 1991-12-18 1995-09-07 Schering Corporation Imidazolyl-alkyl-piperazine and -diazepine derivatives as histamine H3 agonists/antagonists
DE69212844T2 (de) * 1991-12-18 1997-01-09 Schering Corp., Kenilworth, N.J. Imidazolyl oder imidazolylalkyl substituiert mit einem 4- oder 5-gliedrigen stickstoff enthaltenden heterozyklischen ring
US5932596A (en) * 1991-12-18 1999-08-03 Schering Corporation Imidazoylalkyl substituted with a six membered nitrogen containing nitrogen containing heterocyclic ring
US5807872A (en) * 1992-12-16 1998-09-15 Schering Corporation Imidazoylalkyl substituted with a six membered nitrogen containing heterocyclic ring
FR2686084B1 (fr) * 1992-01-10 1995-12-22 Bioprojet Soc Civ Nouveaux derives de l'imidazole, leur preparation et leurs applications therapeutiques.
USRE37303E1 (en) * 1992-01-10 2001-07-31 Institut National Del La Sante Et De La Recherche Medicale Imidazole compounds and their therapeutic applications
US5486526A (en) * 1992-04-01 1996-01-23 The University Of Toledo Histamine H3 -receptor antagonists and therapeutic uses thereof
US5639775A (en) * 1992-04-01 1997-06-17 The University Of Toledo 4-[4'-piperodinyl or 3'-pirrolidinyl] substituted imidazoles as H3 -receptor antagonists and therapeutic uses thereof
BR9306190A (pt) * 1992-04-01 1998-06-23 Univ Toledo Composto composiçao farmacéutica e processo para tratar um indivíduo sofrendo de um distúrbio cognitivo ou uma deficiéncia na atençao ou estímulo
US5648355A (en) * 1994-02-09 1997-07-15 Kos Pharmaceutical, Inc. Method of treatment of endogenous, painful gastrointestinal conditions of non-inflammatory, non-ulcerative origin
US5905152A (en) * 1996-08-08 1999-05-18 Schering Corporation Preparation of aminomethyl-phenylimidazoles
WO2000042023A1 (en) 1999-01-18 2000-07-20 Novo Nordisk A/S Substituted imidazoles, their preparation and use
US6908926B1 (en) 1999-04-16 2005-06-21 Novo Nordisk A/S Substituted imidazoles, their preparation and use
US6437147B1 (en) 2000-03-17 2002-08-20 Novo Nordisk Imidazole compounds
US6610721B2 (en) 2000-03-17 2003-08-26 Novo Nordisk A/S Imidazo heterocyclic compounds
RU2287524C1 (ru) * 2005-03-31 2006-11-20 ООО "Фарминтерпрайсез" Аспартильные производные гистамина, способ их получения, фармацевтическая композиция и их применение в качестве модуляторов активности ферментов антиоксидантной защиты
JP3892894B2 (ja) * 2005-04-28 2007-03-14 大塚製薬株式会社 カルボスチリル化合物の製造法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2586562B1 (fr) * 1985-09-02 1989-03-10 Inst Nat Sante Rech Med Composition pharmaceutique contenant de l'a-methylhistamine

Also Published As

Publication number Publication date
JPH0655728B2 (ja) 1994-07-27
FR2630328A1 (fr) 1989-10-27
FR2630328B1 (fr) 1990-08-24
DE68904586T2 (de) 1993-08-19
US5034539A (en) 1991-07-23
EP0338939B1 (fr) 1993-01-27
ATE85051T1 (de) 1993-02-15
EP0338939A1 (fr) 1989-10-25
JPH037264A (ja) 1991-01-14
DE68904586D1 (de) 1993-03-11

Similar Documents

Publication Publication Date Title
FR2630328B1 (fr) Derive de l'histamine, sa preparation et son application en therapeutique
ES2081187T3 (es) Nuevas naftil-alquil-aminas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen.
EA199800357A1 (ru) Фармацевтические ангиостатические дипептидные композиции и способы их применения
EA199700201A1 (ru) Парентеральные фармацевтические композиции, содержащие алкиламмониевые соли 2-арилпропиновых кислот
NO940523L (no) Nye pyrazin-derivater
ES2063570T3 (es) Nuevos derivados de triazolopirimidina antagonistas de los receptores de la angiotensina ii; sus procedimientos de preparacion, composiciones farmaceuticas que los contienen.
EA199801028A1 (ru) Применение производных п-аминофенола для проготовления фармацевтических композиций, используемых при лечении нейродегенеративных заболеваний
FI94354C (fi) Menetelmä farmaseuttisesti aktiivisten peptidien valmistamiseksi
YU47338B (sh) Novo jedinjenje 4-fluoro-2-// (4-metoksi-2-piridinil)metil-/sulfinil/- 1h-benzimidazol i postupak za njegovo dobijanje
EA199800701A1 (ru) БЕНЗО[С]ХИНОЛИЗИНОВЫЕ ПРОИЗВОДНЫЕ, ИХ ПОЛУЧЕНИЕ И ИСПОЛЬЗОВАНИЕ В КАЧЕСТВЕ ИНГИБИТОРОВ 5a-РЕДУКТАЗ
DE69330601D1 (de) Serotoninergische ergolin derivate
ES2086528T3 (es) Nuevos compuestos biciclicos sustituidos con amino.
NO883468L (no) Fremgangsmaate til fremstilling av farmasoeytiske blandinger inneholdende cyklopeptider som reserpsjonsbefordrere vedapplikasjon paa slimhuden.
DK601888A (da) Anvendelse af 2-pyrimidinyl-1-piperazinderivater
KR900701763A (ko) 1-아미노-5-할로게노우라실, 그의 제조방법 및 이 화합물을 유효성분으로 함유하는 중추신경억제제
FR2539415B1 (fr) Derives de la d-2 imidazoline, leur preparation et leur application en therapeutique
ATE113949T1 (de) Alpha-adrenergische rezeptorantagonisten.
SE8005687L (sv) Nya 10-halogen-e-homoeburnaner jemte sett for deras framstellning
ES2076054T3 (es) Nuevas amino-alquil-cromonas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen.
ES2063157T3 (es) Nuevos derivados del indol, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
DK316682A (da) Fremgangsmaade til fremstilling af optisk aktive dipeptider
ATE114310T1 (de) Alpha-adrenergische rezeptorantagonisten.
DK0814813T3 (da) Anvendelse af penciclovir til behandling af human herpesvirus-8
ES2123038T3 (es) Nuevos derivados pirrolo-tieno-pirazinicos, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.
DK34882A (da) Fremgangsmaade til fremstilling af peptidderivater

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 338939

Country of ref document: ES