ES2053465T3 - Un metodo para preparar una preparacion de sucralfato en forma de suspension. - Google Patents

Un metodo para preparar una preparacion de sucralfato en forma de suspension.

Info

Publication number
ES2053465T3
ES2053465T3 ES87106961T ES87106961T ES2053465T3 ES 2053465 T3 ES2053465 T3 ES 2053465T3 ES 87106961 T ES87106961 T ES 87106961T ES 87106961 T ES87106961 T ES 87106961T ES 2053465 T3 ES2053465 T3 ES 2053465T3
Authority
ES
Spain
Prior art keywords
sucralphate
preparation
suspension
water
esophagitis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87106961T
Other languages
English (en)
Inventor
Kouji Ishihara
Toshichika Ogasawara
Kazuo Igusa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2053465T3 publication Critical patent/ES2053465T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Dental Preparations (AREA)
  • Materials For Medical Uses (AREA)
  • Steroid Compounds (AREA)

Abstract

SE DESCRIBE UNA PREPARACION DE SUCRALFATO EN FORMA DE UNA SUSPENSION QUE ES ADECUADA PARA CURAR LA ESOFAGITIS O LA ULCERA ESOFAGICA, Y UN METODO DE PREPARACION DE LA MISMA. LA PREPARACION DE SUCRALFATO COMPRENDE SUCRALFATO SUSPENDIDO EN UNA SOLUCION ACUOSA O EN UNA SUSPENSION ACUOSA DE SUSTANCIA POLIMERICA SOLUBLE EN AGU O INSOLUBLE EN AGUA, COMO AGENTE DE SUSPENSION O COMO AGENTE ESPESANTE, Y TIENE UNA VISCOSIDAD EN EL INTERVALO DE 1000 A 5000 CB. ESTA PREPARACION DE SUCRALFATO SE ADHIERE SELECTIVAMENTE A LOS PUNTOS ULCERADOS O INFLAMADOS DE LA MUCOSA DEL ESOFAGO Y ES MUY EFICAZ COMO CURA PARA LA ESOFAGITIS O PARA LA ULCERA ESOFAGICA.
ES87106961T 1986-05-16 1987-05-14 Un metodo para preparar una preparacion de sucralfato en forma de suspension. Expired - Lifetime ES2053465T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11068686 1986-05-16

Publications (1)

Publication Number Publication Date
ES2053465T3 true ES2053465T3 (es) 1994-08-01

Family

ID=14541876

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87106961T Expired - Lifetime ES2053465T3 (es) 1986-05-16 1987-05-14 Un metodo para preparar una preparacion de sucralfato en forma de suspension.

Country Status (14)

Country Link
EP (1) EP0245855B1 (es)
JP (1) JP2583054B2 (es)
KR (1) KR950005870B1 (es)
AT (1) ATE84218T1 (es)
AU (1) AU594765B2 (es)
CA (1) CA1307465C (es)
DE (1) DE3783390T2 (es)
DK (1) DK164199C (es)
ES (1) ES2053465T3 (es)
FI (1) FI91598C (es)
HK (1) HK65293A (es)
NO (1) NO175516C (es)
SG (1) SG64593G (es)
ZA (1) ZA873496B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5916880A (en) * 1987-12-21 1999-06-29 Bukh Meditec A/S Reduction of skin wrinkling using sulphated sugars
DK505488D0 (da) * 1987-12-21 1988-09-09 Bar Shalom Daniel Middel og anvendelse af samme
US5709873A (en) * 1988-02-26 1998-01-20 Niels Bukh A/S Method of treating conditions of teeth and their supporting tissue
DK505588D0 (da) * 1988-02-26 1988-09-09 Jesper Hamburger Middel og anvendelse af samme
JP2735559B2 (ja) * 1988-03-02 1998-04-02 中外製薬株式会社 懸濁液
US4975281A (en) * 1989-01-30 1990-12-04 E. R. Squibb & Sons, Inc. Anti-ulcer composition
US5618798A (en) * 1989-04-20 1997-04-08 Bar-Shalom; Daniel Use of sucralfate to treat baldness
IL95642A0 (en) * 1989-09-15 1991-06-30 Pehrom Pharmaceutical Corp Topical preparations for treatment of ulcers and other lesions
ATE209498T1 (de) * 1990-08-31 2001-12-15 Chugai Pharmaceutical Co Ltd Herstellung einer vorratslösung von in wasser suspendiertem sucralfat
FI924470A0 (fi) * 1992-10-05 1992-10-05 Orion Yhtymae Oy Sukralfatpreparat
IT1264546B1 (it) * 1993-07-30 1996-10-02 Lisapharma Spa Composizione farmaceutica ad attivita' antiacida in forma di sospensione a base di gel di sucralfato
US5783568A (en) * 1994-06-10 1998-07-21 Sugen, Inc. Methods for treating cancer and other cell proliferative diseases
US6319513B1 (en) 1998-08-24 2001-11-20 The Procter & Gamble Company Oral liquid mucoadhesive compounds
US6723342B1 (en) 1999-02-08 2004-04-20 Fmc Corporation Edible coating composition
US6432448B1 (en) * 1999-02-08 2002-08-13 Fmc Corporation Edible coating composition
AU2001270304A1 (en) 2000-07-07 2002-01-21 The Administrators Of The Tulane Educational Fund Methods for protection of stratified squamous epithelium against injury by noxious substances and novel agents for use therefor
EP1339395A2 (en) 2000-11-28 2003-09-03 Fmc Corporation Edible pga (propylene glycol alginate) coating composition
US6932861B2 (en) 2000-11-28 2005-08-23 Fmc Corporation Edible PGA coating composition
US10716802B2 (en) 2013-03-15 2020-07-21 The Brigham And Women's Hospital, Inc. Compounds to modulate intestinal absorption of nutrients
JP6365235B2 (ja) 2014-10-28 2018-08-01 ライオン株式会社 液状組成物
WO2017053970A1 (en) 2015-09-24 2017-03-30 The Brigham And Women's Hospital, Inc. Water-activated mucoadhesive compositions to reduce intestinal absorption of nutrients
JP2017178881A (ja) * 2016-03-31 2017-10-05 小林製薬株式会社 経口組成物
KR101837104B1 (ko) * 2017-04-14 2018-03-09 한국프라임제약주식회사 수크랄페이트 합성 방법 및 이에 의한 수크랄페이트
EP3941479A1 (en) * 2019-03-20 2022-01-26 Reponex Pharmaceuticals A/S Targeting biological agents to mucosal defects of the gastrointestinal tract

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3432489A (en) * 1965-11-05 1969-03-11 Chugai Pharmaceutical Co Ltd Disaccharide polysulfate aluminium compound and method
DE3315800A1 (de) * 1983-04-30 1984-10-31 Merck Patent Gmbh, 6100 Darmstadt Verfahren zur herstellung eines granulats
CA1218601A (en) * 1983-09-02 1987-03-03 Angel B. Casillan Sucralfate suspension
DE3430809A1 (de) * 1984-08-22 1986-03-06 Merck Patent Gmbh, 6100 Darmstadt Sucralfat-suspension

Also Published As

Publication number Publication date
EP0245855A3 (en) 1988-06-08
HK65293A (en) 1993-07-16
AU594765B2 (en) 1990-03-15
ZA873496B (en) 1987-11-09
FI91598C (fi) 1994-07-25
EP0245855A2 (en) 1987-11-19
DE3783390D1 (de) 1993-02-18
JP2583054B2 (ja) 1997-02-19
SG64593G (en) 1993-08-06
FI91598B (fi) 1994-04-15
NO872002D0 (no) 1987-05-14
JPS63107934A (ja) 1988-05-12
DE3783390T2 (de) 1993-05-06
EP0245855B1 (en) 1993-01-07
DK243587D0 (da) 1987-05-13
NO175516C (no) 1994-10-26
ATE84218T1 (de) 1993-01-15
DK164199B (da) 1992-05-25
NO872002L (no) 1987-11-17
DK164199C (da) 1992-10-19
DK243587A (da) 1987-11-17
KR950005870B1 (ko) 1995-06-02
FI872169L (fi) 1987-11-17
FI872169A0 (fi) 1987-05-15
KR890001515A (ko) 1989-03-27
AU7279587A (en) 1987-11-19
NO175516B (no) 1994-07-18
CA1307465C (en) 1992-09-15

Similar Documents

Publication Publication Date Title
FI91598B (fi) Menetelmä ruokatorven limakalvon tulehdusta parantavasti vaikuttavan, suspension muodossa olevan sukralfaattituotteen valmistamiseksi
ES2054613T3 (es) Un metodo para preparar una formulacion de liberacion mantenida.
ES8706037A1 (es) Un procedimiento para formar un articulo conformado sin capa o pelicula exterior.
GB1510999A (en) Pharmaceutical preparation in the form of a foil having an active substance incorporated therein
PE12597A1 (es) Sales de quitosan con mejores propiedades absorbentes y proceso para su preparacion
AT323181B (de) Verfahren zur herstellung von neuen pyrrolo (3,4-b) pyrazinderivaten sowie von deren säureadditionssalzen
IT8367971A0 (it) Procedimento per la produzione di un supporto da usare nella formazione di film poliuretanici
ATE138940T1 (de) Wasserlösliche hyaluronsäurederivate
DK124091D0 (da) Farmaceutisk genprodukt
ES2102367T3 (es) Amidas de acidos isoxazol-4-carboxilicos y amidas de acidos hidroxialquiliden-cianoaceticos, medicamentos que contienen estos compuestos y su utilizacion.
ES2046364T3 (es) Pasta acuosa de hidroxido de niquel con una elevada fluidez.
IT7819806A0 (it) Derivati del 2h-benzofuran-3-one eprocedimento per la loro preparazione.
ES2111032T5 (es) Carboxialquil polisacaridos y procedimiento de fabricacion de los mismos.
ES8406500A1 (es) Procedimiento para la preparacion de derivados de beta-d-galactosa
IT7926964A0 (it) Procedimento per la produzione di derivati dell'acido fenossicarbossilico.
FI872774A7 (fi) Bentsimidatsolit, niiden valmistus, formulointi ja käyttö mahahappoerityksen inhibiittoreina.
IT1163698B (it) Derivati di 1-ftalazone, procedimento per la loro preparazione, e loro impiego
IT1204912B (it) Derivati del 9,10-diidro fenantrene e procedimento per la loro preparazione
IT1037084B (it) Procedimento per la preparazione di derivati di ih tetrazol 5 tiolo e ih tetrazol 5 tioli i sostituiti e procedimentper la loro preparazione
ES531974A0 (es) Procedimiento para la produccion de una solucion organica de una base organica insoluble en agua
MX6161E (es) Procedimiento para la preparacion de bis-(dihidroxipropilamidas)del acido 5-hidroxipropionilamino-2,4,6-triyodo-isoftalico,facilmente solubles en el agua
ATE82269T1 (de) Verfahren zur herstellung von 1-pyrazolinen.
IT7819615A0 (it) Derivati del 2h-benzofuran-3-one eprocedimento per la loro preparazione.
ES509605A0 (es) Procedimiento para depurar y desodorizar los gases producidos por la descomposicion de los cadaveres en el interior de los ataudes hermeticos.
ATE49599T1 (de) 2-sulfamoylbenzo(b)thiophen-derivate, ihre herstellung und pharmazeutische zubereitung zur behandlung von erhoehtem augeninnendruck.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 245855

Country of ref document: ES