ES2053562T3 - Irradiacion gamma de mezclas de colageno y un mineral. - Google Patents

Irradiacion gamma de mezclas de colageno y un mineral.

Info

Publication number
ES2053562T3
ES2053562T3 ES87309810T ES87309810T ES2053562T3 ES 2053562 T3 ES2053562 T3 ES 2053562T3 ES 87309810 T ES87309810 T ES 87309810T ES 87309810 T ES87309810 T ES 87309810T ES 2053562 T3 ES2053562 T3 ES 2053562T3
Authority
ES
Spain
Prior art keywords
mineral
gamma irradiation
collagen mixtures
collagen
mixtures
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87309810T
Other languages
English (en)
Inventor
Thomas L Smestad
Daniel Prows
George H Chu
Diana M Hendriks
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Collagen Aesthetics Inc
Original Assignee
Collagen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Collagen Corp filed Critical Collagen Corp
Application granted granted Critical
Publication of ES2053562T3 publication Critical patent/ES2053562T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/08—Radiation
    • A61L2/081—Gamma radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00—Surgery
    • Y10S128/08—Collagen
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/92—Method or apparatus for preparing or treating prosthetic
    • Y10S623/923—Bone

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Materials For Medical Uses (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)

Abstract

UN PROCEDIMIENTO PARA ESTERILIZACION DE COMPOSICIONES DE COLAGENO/MINERAL UTILIZANDO RADIACION GAMMA SE LLEVA A CABO EN CONDICIONES QUE GENERAN UN PRODUCTO CON PROPIEDADES DE MANEJO Y DE BIOCOMPATIBILIDAD DESEADAS.
ES87309810T 1986-11-06 1987-11-05 Irradiacion gamma de mezclas de colageno y un mineral. Expired - Lifetime ES2053562T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/928,306 US4865602A (en) 1986-11-06 1986-11-06 Gamma irradiation of collagen/mineral mixtures
CA000616394A CA1320451C (en) 1986-11-06 1992-06-02 Gamma irradiation of collagen/mineral mixtures

Publications (1)

Publication Number Publication Date
ES2053562T3 true ES2053562T3 (es) 1994-08-01

Family

ID=25673243

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87309810T Expired - Lifetime ES2053562T3 (es) 1986-11-06 1987-11-05 Irradiacion gamma de mezclas de colageno y un mineral.

Country Status (7)

Country Link
US (3) US4865602A (es)
EP (1) EP0270254B1 (es)
JP (2) JPH062151B2 (es)
AU (1) AU603744B2 (es)
CA (1) CA1320451C (es)
ES (1) ES2053562T3 (es)
GR (1) GR3007382T3 (es)

Families Citing this family (101)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4888366A (en) * 1984-10-24 1989-12-19 Collagen Corporation Inductive collagen-based bone repair preparations
US5001169A (en) * 1984-10-24 1991-03-19 Collagen Corporation Inductive collagen-based bone repair preparations
US5246457A (en) * 1985-03-28 1993-09-21 Collagen Corporation Xenogeneic collagen/mineral preparations in bone repair
US4865602A (en) * 1986-11-06 1989-09-12 Collagen Corporation Gamma irradiation of collagen/mineral mixtures
GB8708009D0 (en) * 1987-04-03 1987-05-07 Clayton Found Res Injectable soft tissue augmentation materials
US5306311A (en) * 1987-07-20 1994-04-26 Regen Corporation Prosthetic articular cartilage
US5735902A (en) * 1987-07-20 1998-04-07 Regen Biologics, Inc. Hand implant device
IT1215881B (it) * 1988-02-16 1990-02-22 Giancarlo Foresti Sussidio chirurgico ad azione osteotropa.
US5223029A (en) * 1988-08-10 1993-06-29 Nitta Gelatin Inc. Hardening material for medical and dental use
US5643464A (en) * 1988-11-21 1997-07-01 Collagen Corporation Process for preparing a sterile, dry crosslinking agent
US5204382A (en) * 1992-02-28 1993-04-20 Collagen Corporation Injectable ceramic compositions and methods for their preparation and use
EP1120439B1 (en) * 1992-02-28 2004-06-16 Cohesion Technologies, Inc. Injectable ceramic compositions and methods for their preparation and use
US5358935A (en) * 1992-11-19 1994-10-25 Robert Allen Smith Nonantigenic keratinous protein material
US5362442A (en) 1993-07-22 1994-11-08 2920913 Canada Inc. Method for sterilizing products with gamma radiation
US20040067157A1 (en) * 1993-07-22 2004-04-08 Clearant, Inc. Methods for sterilizing biological materials
US5531791A (en) * 1993-07-23 1996-07-02 Bioscience Consultants Composition for repair of defects in osseous tissues, method of making, and prosthesis
JP2775386B2 (ja) * 1993-10-04 1998-07-16 科学技術庁無機材質研究所長 アパタイト・有機物複合体とその製造法
US5721150A (en) * 1993-10-25 1998-02-24 Lsi Logic Corporation Use of silicon for integrated circuit device interconnection by direct writing of patterns therein
US5422068A (en) * 1994-01-05 1995-06-06 Shalaby; Shalaby W. Radiochemical sterilization
US6337389B1 (en) 1995-03-17 2002-01-08 Bioscience Consultants, L.L.C. Method and process for the production of collagen preparations from invertebrate marine animals and compositions thereof
US5674292A (en) * 1995-06-07 1997-10-07 Stryker Corporation Terminally sterilized osteogenic devices and preparation thereof
AU1535097A (en) 1996-01-17 1997-08-11 Osteotech, Inc. Process and apparatus for producing flexible sheets from demineralized, elongate, bone particles
US5788941A (en) * 1996-01-31 1998-08-04 Steris Corporation Method of sterilization of bone tussue
US8865788B2 (en) * 1996-02-13 2014-10-21 The General Hospital Corporation Radiation and melt treated ultra high molecular weight polyethylene prosthetic devices
US20020156536A1 (en) * 1996-02-13 2002-10-24 Harris William H. Polyethylene hip joint prosthesis with extended range of motion
US8563623B2 (en) * 1996-02-13 2013-10-22 The General Hospital Corporation Radiation melt treated ultra high molecular weight polyethylene prosthetic devices
US5792478A (en) * 1996-07-08 1998-08-11 Advanced Uro Science Tissue injectable composition and method of use
AU6021598A (en) 1997-01-09 1998-08-03 Cohesion Technologies, Inc. Methods and apparatuses for making swellable uniformly shaped devices from polymeric materials
US6017366A (en) * 1997-04-18 2000-01-25 W. L. Gore & Associates, Inc. Resorbable interposition arthroplasty implant
US5889075A (en) * 1997-10-10 1999-03-30 United States Surgical Corporation Irradiated surgical suture and method for making same
US20040081704A1 (en) 1998-02-13 2004-04-29 Centerpulse Biologics Inc. Implantable putty material
WO2000001238A1 (en) * 1998-07-06 2000-01-13 Kajander E Olavi Methods for eradication of nanobacteria
US6706290B1 (en) 1998-07-06 2004-03-16 Olvai E. Kajander Methods for eradication of nanobacteria
FR2786400B1 (fr) * 1998-11-30 2002-05-10 Imedex Biomateriaux Procede de preparation d'un materiau collagenique a vitesse de biodegradation in vivo controlee et materiaux obtenus
DE60006356T2 (de) * 1999-02-04 2004-09-09 SDGI Holding, Inc., Wilmington Hochmineralisierte osteogene schwammzusammensetzungen und ihre verwendung
AU770196B2 (en) * 1999-02-04 2004-02-12 Warsaw Orthopedic, Inc. Osteogenic paste compositions and uses thereof
US20030228288A1 (en) 1999-10-15 2003-12-11 Scarborough Nelson L. Volume maintaining osteoinductive/osteoconductive compositions
US20040086420A1 (en) * 2000-03-23 2004-05-06 Macphee Martin J. Methods for sterilizing serum or plasma
KR20030011279A (ko) * 2000-03-23 2003-02-07 클리어런트, 인코포레이티드 생물학적 성분의 살균방법
US9387094B2 (en) * 2000-07-19 2016-07-12 Warsaw Orthopedic, Inc. Osteoimplant and method of making same
EP1304980B1 (en) * 2000-07-31 2007-05-16 Massachusetts General Hospital Monopolar constrained acetabular component
US7323193B2 (en) * 2001-12-14 2008-01-29 Osteotech, Inc. Method of making demineralized bone particles
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US20020115742A1 (en) * 2001-02-22 2002-08-22 Trieu Hai H. Bioactive nanocomposites and methods for their use
US6682695B2 (en) * 2001-03-23 2004-01-27 Clearant, Inc. Methods for sterilizing biological materials by multiple rates
US6696060B2 (en) 2001-06-14 2004-02-24 Clearant, Inc. Methods for sterilizing preparations of monoclonal immunoglobulins
US20030026770A1 (en) * 2001-07-25 2003-02-06 Szymaitis Dennis W. Periodontal regeneration composition and method of using same
US7105182B2 (en) * 2001-07-25 2006-09-12 Szymaitis Dennis W Periodontal regeneration composition and method of using same
US6946098B2 (en) 2001-08-10 2005-09-20 Clearant, Inc. Methods for sterilizing biological materials
US7252799B2 (en) * 2001-08-31 2007-08-07 Clearant, Inc. Methods for sterilizing preparations containing albumin
US6749851B2 (en) 2001-08-31 2004-06-15 Clearant, Inc. Methods for sterilizing preparations of digestive enzymes
WO2003020327A2 (en) * 2001-09-06 2003-03-13 Bone Sa A cross-linked collagenous biomaterial
US20110091353A1 (en) * 2001-09-24 2011-04-21 Wilson Burgess Methods for Sterilizing Tissue
US20030185702A1 (en) * 2002-02-01 2003-10-02 Wilson Burgess Methods for sterilizing tissue
US20030095890A1 (en) * 2001-09-24 2003-05-22 Shirley Miekka Methods for sterilizing biological materials containing non-aqueous solvents
EP2295088B1 (en) * 2001-10-12 2016-12-07 Warsaw Orthopedic, Inc. Improved bone graft
US20030124023A1 (en) * 2001-12-21 2003-07-03 Wilson Burgess Method of sterilizing heart valves
US20030181371A1 (en) * 2001-12-28 2003-09-25 Angiotech Pharmaceuticals, Inc. Compositions and methods of using collajolie
US20030180181A1 (en) * 2002-02-01 2003-09-25 Teri Greib Methods for sterilizing tissue
US7514248B2 (en) 2002-04-18 2009-04-07 University Of Florida Research Foundation, Inc. Process for making organic/inorganic composites
US7514249B2 (en) * 2002-04-18 2009-04-07 The University Of Florida Research Foundation, Inc. Biomimetic organic/inorganic composites
US7455854B2 (en) * 2002-04-18 2008-11-25 University Of Florida Research Foundation, Inc. Method for producing a mineral fiber
WO2003092760A1 (de) * 2002-04-29 2003-11-13 Biomet Deutschland Gmbh Strukturierte komposite als matrix (scaffold) für das tissue engineering von knochen
US6933285B2 (en) * 2002-05-10 2005-08-23 The Ohio State University Flavin N-oxides: new anti-cancer agents and pathogen eradication agents
US7166133B2 (en) * 2002-06-13 2007-01-23 Kensey Nash Corporation Devices and methods for treating defects in the tissue of a living being
US6908591B2 (en) * 2002-07-18 2005-06-21 Clearant, Inc. Methods for sterilizing biological materials by irradiation over a temperature gradient
US20040013562A1 (en) * 2002-07-18 2004-01-22 Wilson Burgess Methods for sterilizing milk.
US20060147501A1 (en) * 2003-02-28 2006-07-06 Hillas Patrick J Collagen compositions and biomaterials
KR20060031808A (ko) * 2003-06-11 2006-04-13 오스테오테크, 인코포레이티드 뼈 임플란트 및 그의 제조 방법
JP2005169008A (ja) * 2003-12-15 2005-06-30 Nipro Corp 生体適合性材料の滅菌方法
US20070190101A1 (en) * 2004-03-31 2007-08-16 Chunlin Yang Flowable bone grafts
US7678385B2 (en) * 2004-04-28 2010-03-16 Biomet Manufacturing Corp. Irradiated implantable bone material
US20050244450A1 (en) * 2004-04-28 2005-11-03 Reddi A H Heat-treated implantable bone material
WO2006078282A2 (en) 2004-04-28 2006-07-27 Angiotech Biomaterials Corporation Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
US7722895B1 (en) 2004-09-20 2010-05-25 Warsaw Orthopedic, Inc. Osteogenic implants with combined implant materials, and materials and methods for same
US7857853B2 (en) * 2005-04-29 2010-12-28 Sdgi Holdings, Inc Synthetic loadbearing collagen-mineral composites useful for spinal implants, and methods of manufacture
US8506646B2 (en) * 2005-04-29 2013-08-13 Warsaw Orthopedic, Inc. Multi-purpose medical implant devices
DE202005009755U1 (de) * 2005-06-21 2005-09-08 Cervitech, Inc. Halter für Zwischenwirbelprothesen
US8920827B2 (en) * 2005-10-21 2014-12-30 Wake Forest University Health Sciences Keratin bioceramic compositions
WO2007056671A1 (en) * 2005-11-02 2007-05-18 Osteotech, Inc. Hemostatic bone graft
US8048857B2 (en) 2006-12-19 2011-11-01 Warsaw Orthopedic, Inc. Flowable carrier compositions and methods of use
US7718616B2 (en) 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
US20120195938A1 (en) * 2007-05-30 2012-08-02 James Louis Rutkowski Formulations and methods for recovery from dental surgery
US9511076B2 (en) * 2008-05-30 2016-12-06 Clarion Research Group Formulations and methods for recovery from dental surgery
US9616153B2 (en) 2008-04-17 2017-04-11 Warsaw Orthopedic, Inc. Rigid bone graft substitute
US20090263507A1 (en) * 2008-04-18 2009-10-22 Warsaw Orthopedic, Inc. Biological markers and response to treatment for pain, inflammation, neuronal or vascular injury and methods of use
KR20110086045A (ko) * 2008-10-24 2011-07-27 오스테오테크, 인코포레이티드 뼈 형성 촉진용 조성물 및 뼈 형성 촉진방법
US20130045923A1 (en) * 2009-08-28 2013-02-21 Tissue Science Laboratories Plc Collagenous material
US9636435B2 (en) * 2010-07-08 2017-05-02 Lifecell Corporation Method for shaping tissue matrices
AU2011329054B2 (en) 2010-11-15 2015-05-28 Zimmer Orthobiologics, Inc. Bone void fillers
CA2818166C (en) 2010-11-17 2019-04-30 Wake Forest University Health Sciences Keratin compositions for treatment of bone deficiency or injury
US10016528B2 (en) 2013-09-09 2018-07-10 Eran Rosines Biologic prosthesis and methods of production and use
CZ307219B6 (cs) * 2015-10-09 2018-04-04 Ăšstav struktury a mechaniky hornin AVÄŚR, v.v.i. Biomateriál na bázi želatiny pro výrobu kostních náhrad a výplní a způsob jeho přípravy
CA3013296A1 (en) 2016-02-11 2017-08-17 Lifecell Corporation Methods for stabilizing collagen-containing tissue products against enzymatic degradation
US10058159B2 (en) * 2016-12-01 2018-08-28 Richard L. Kronenthal Sterile compositions for human cosmetic products
DK3544643T3 (da) 2017-12-14 2020-07-06 Geistlich Pharma Ag Knogleerstatningsmateriale
KR102330140B1 (ko) 2017-12-14 2021-11-23 가이스틀리히 파마 아게 건조 임플란트 조성물 및 주사가능한 수성 임플란트 제형
TW202016288A (zh) * 2018-06-29 2020-05-01 國立研究開發法人量子科學技術研究開發機構 細胞培養用水凝膠、凝膠套組、細胞培養物之製造方法、及細胞培養用水凝膠之製造方法
RO134200B1 (ro) 2018-11-23 2023-07-28 Institutul Naţional De Cercetare-Dezvoltare Textile Pielărie - Sucursala Institutul De Cercetare Pielărie Încălţăminte Procedeu de tratare şi piei conservate prin iradiere gama
WO2020249711A1 (en) 2019-06-14 2020-12-17 Geistlich Pharma Ag Injectable aqueous implant formulation containing ascorbic acid
TWI869413B (zh) 2019-06-14 2025-01-11 瑞士商蓋茲特利製藥公司 骨替代材料之膠原蛋白基質或顆粒摻合物及其用途

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3443261A (en) * 1967-09-01 1969-05-13 Fmc Corp Prosthetic structures from microcrystalline collagen
US3767437A (en) * 1971-10-20 1973-10-23 Avicon Inc Phosthetic structures derived from collagen
US3949073A (en) * 1974-11-18 1976-04-06 The Board Of Trustees Of Leland Stanford Junior University Process for augmenting connective mammalian tissue with in situ polymerizable native collagen solution
CH615099A5 (es) * 1975-08-07 1980-01-15 Ulf Sven Erik Rothman
CA1073360A (en) * 1975-10-22 1980-03-11 John R. Daniels Non-antigenic collagen and articles of manufacture
DE2843963A1 (de) * 1978-10-09 1980-04-24 Merck Patent Gmbh Im koerper resorbierbare geformte masse auf basis von kollagen und ihre verwendung in der medizin
US4349470A (en) * 1979-09-14 1982-09-14 Battista Orlando A Protein polymer hydrogels
EP0030583B1 (de) * 1979-12-18 1984-06-13 Oscobal Ag Knochenersatzmaterial und Verfahren zur Herstellung eines Knochenersatzmaterials
US4314380A (en) * 1980-09-26 1982-02-09 Koken Co., Ltd. Artificial bone
JPS5841A (ja) * 1981-06-22 1983-01-05 Matsushita Electric Ind Co Ltd パイプヒ−タ応用熱交換器
DE3124981A1 (de) * 1981-06-25 1983-01-13 Dr. Ruhland Nachfolger GmbH, 8425 Neustadt Wirkstoffhaltige kollageneinlage zum einfuehren in knochen oder weichteile und verfahren zu deren herstellung
JPS5858041A (ja) * 1981-10-05 1983-04-06 三菱鉱業セメント株式会社 骨欠損部及び空隙部充てん材
US4424208A (en) * 1982-01-11 1984-01-03 Collagen Corporation Collagen implant material and method for augmenting soft tissue
US4409332A (en) * 1982-01-12 1983-10-11 Jefferies Steven R Collagen-enzyme conjugates that exhibit no inflammatory response and method for making the same
US4582640A (en) * 1982-03-08 1986-04-15 Collagen Corporation Injectable cross-linked collagen implant material
EP0108661A1 (en) * 1982-10-04 1984-05-16 Merck & Co. Inc. Stabilized hydroxypropyl cellulose ophthalmic inserts and process to sterilize the same
DE3479402D1 (en) * 1984-06-12 1989-09-21 Oscobal Ag Method of producing a bone replacement material
US4789663A (en) * 1984-07-06 1988-12-06 Collagen Corporation Methods of bone repair using collagen
EP0169001A3 (en) * 1984-07-17 1987-11-25 Collagen Corporation Collagen coated bone implants
US4553974A (en) * 1984-08-14 1985-11-19 Mayo Foundation Treatment of collagenous tissue with glutaraldehyde and aminodiphosphonate calcification inhibitor
US4642117A (en) * 1985-03-22 1987-02-10 Collagen Corporation Mechanically sheared collagen implant material and method
US4992226A (en) * 1985-03-28 1991-02-12 Collagen Corporation Method of making molds with xenogeneic collagen/mineral preparations for bone repair
CA1260391A (en) * 1985-03-28 1989-09-26 Karl A. Piez Xenogeneic collagen/mineral preparations in bone repair
EP0246638A3 (en) * 1986-05-23 1989-03-15 Cordis Corporation Biologically modified synthetic grafts
US4865602A (en) * 1986-11-06 1989-09-12 Collagen Corporation Gamma irradiation of collagen/mineral mixtures

Also Published As

Publication number Publication date
AU603744B2 (en) 1990-11-22
JPH062151B2 (ja) 1994-01-12
CA1320451C (en) 1993-07-20
EP0270254A2 (en) 1988-06-08
JPH0622571B2 (ja) 1994-03-30
US5123925A (en) 1992-06-23
AU8068087A (en) 1988-05-12
EP0270254B1 (en) 1993-03-10
JPH05305133A (ja) 1993-11-19
US4865602A (en) 1989-09-12
GR3007382T3 (es) 1993-07-30
JPS63132664A (ja) 1988-06-04
US5035715A (en) 1991-07-30
EP0270254A3 (en) 1990-03-07

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