ES2053637T3 - Anticuerpos monoclonales de sustancia que enlaza antitrombina y sus usos. - Google Patents

Anticuerpos monoclonales de sustancia que enlaza antitrombina y sus usos.

Info

Publication number
ES2053637T3
ES2053637T3 ES88112047T ES88112047T ES2053637T3 ES 2053637 T3 ES2053637 T3 ES 2053637T3 ES 88112047 T ES88112047 T ES 88112047T ES 88112047 T ES88112047 T ES 88112047T ES 2053637 T3 ES2053637 T3 ES 2053637T3
Authority
ES
Spain
Prior art keywords
substance
antithrombine
links
monoclonal antibodies
monoclonal antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88112047T
Other languages
English (en)
Inventor
Nobuo Aoki
Takao Nagoya
Shigeru Kimura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kowa Co Ltd
Original Assignee
Kowa Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kowa Co Ltd filed Critical Kowa Co Ltd
Application granted granted Critical
Publication of ES2053637T3 publication Critical patent/ES2053637T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

EL PRESENTE INVENTO PROVEE UN ANTICUERPO MONOCLONAL ESPECIFICO PARA UNA SUSTANCIA (TM) ASTRINGENTE DE TROMBOSIS, HIBRIDOMAS QUE PRODUCEN EL ANTICUERPO MONOCLONAL, UN PROCESO DE PURIFICACION DE TM QUE DESCRIBE EL USO DEL ANTICUERPO MONOCLONAL COMO UN INMUNO ADSORBENTE, COMO TAMBIEN UN INMUNO ENSAYO DE TM QUE DESCRIBE EL USO DEL ANTICUERPO MONOCLONAL.
ES88112047T 1987-08-13 1988-07-26 Anticuerpos monoclonales de sustancia que enlaza antitrombina y sus usos. Expired - Lifetime ES2053637T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP62202517A JPS6445398A (en) 1987-08-13 1987-08-13 Antithrombin-binding substance monoclonal antibody, hybridoma producing said antibody and method for purifying and measuring thrombin-binding substance utilizing said monoclonal antibody
JP4216068A JPH05304953A (ja) 1987-08-13 1992-08-13 抗トロンビン結合性物質モノクローナル抗体を産生するハイブリドーマ

Publications (1)

Publication Number Publication Date
ES2053637T3 true ES2053637T3 (es) 1994-08-01

Family

ID=26513431

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88112047T Expired - Lifetime ES2053637T3 (es) 1987-08-13 1988-07-26 Anticuerpos monoclonales de sustancia que enlaza antitrombina y sus usos.

Country Status (7)

Country Link
US (1) US5098829A (es)
EP (1) EP0306680B1 (es)
JP (2) JPS6445398A (es)
KR (1) KR960002740B1 (es)
CA (1) CA1335180C (es)
DE (1) DE3888604T2 (es)
ES (1) ES2053637T3 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2044629A1 (en) * 1989-11-02 1991-05-03 Kimihiko Matsuzawa Method for the immunological assay of human thrombomodulin, reagent therefor and kit therefor
JPH0736019B2 (ja) * 1989-12-27 1995-04-19 富士薬品工業株式会社 新規な抗ヒトトロンボモジュリンモノクローナル抗体によるヒトトロンボモジュリンおよびその分解産物の定量方法
JP2697289B2 (ja) * 1990-11-10 1998-01-14 ブラザー工業株式会社 ミシンのための駆動装置
US7240940B2 (en) * 2004-09-23 2007-07-10 89908, Inc. Vehicle cargo bed extender
PT2781221T (pt) 2011-11-15 2020-06-01 Asahi Kasei Pharma Corp Medicamento para tratamento e/ou melhoria de sepsia
DK2857037T3 (da) 2012-05-31 2019-07-22 Univ Kinki Middel til forebyggelse og/eller behandling af perifere neuropatiske smerter forårsaget af anticancerlægemiddel
CA3112679A1 (en) 2018-09-28 2020-04-02 Asahi Kasei Pharma Corporation Medicament for mitigating conditions and/or suppressing onset of peripheral neuropathy induced by anti-malignant tumor agent
BR112021007460A2 (pt) 2018-10-22 2021-11-03 Asahi Kasei Pharma Corp Medicamento para tratamento terapêutico e/ou melhora de um paciente com sepse

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4775624A (en) * 1985-02-08 1988-10-04 Eli Lilly And Company Vectors and compounds for expression of human protein C
DE3750664T2 (de) * 1986-07-15 1995-06-22 Kowa Co Throminbindende Substanz und Verfahren zu ihrer Herstellung.
DE3876124T2 (de) * 1987-04-01 1993-05-06 Mitsubishi Gas Chemical Co Immunoassay fuer thrombomodulin.

Also Published As

Publication number Publication date
DE3888604T2 (de) 1994-10-27
EP0306680A3 (en) 1990-02-28
JPS6445398A (en) 1989-02-17
JPH058679B2 (es) 1993-02-02
EP0306680B1 (en) 1994-03-23
JPH05304953A (ja) 1993-11-19
KR890003405A (ko) 1989-04-14
EP0306680A2 (en) 1989-03-15
KR960002740B1 (ko) 1996-02-26
DE3888604D1 (de) 1994-04-28
US5098829A (en) 1992-03-24
CA1335180C (en) 1995-04-11

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