ES2053967T3 - Identificacion de celulas nk y linfocitos t citotoxicos. - Google Patents

Identificacion de celulas nk y linfocitos t citotoxicos.

Info

Publication number
ES2053967T3
ES2053967T3 ES89300107T ES89300107T ES2053967T3 ES 2053967 T3 ES2053967 T3 ES 2053967T3 ES 89300107 T ES89300107 T ES 89300107T ES 89300107 T ES89300107 T ES 89300107T ES 2053967 T3 ES2053967 T3 ES 2053967T3
Authority
ES
Spain
Prior art keywords
cells
lymphocytes
react
reagent
cytotoxic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89300107T
Other languages
English (en)
Inventor
Lewis L Lanier
Joseph H Phillips
Anne L Jackson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Application granted granted Critical
Publication of ES2053967T3 publication Critical patent/ES2053967T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/283—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y10S530/809—Fused cells, e.g. hybridoma

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

SE PROPORCIONA UN METODO PARA DISTINGUIR ENTRE CELULAS NK Y LINFOCITOS T, QUE CONSISTE EN PONER EN CONTACTO UNA MUESTRA QUE CONTIENE LINFOCITOS CON UN PRIMER REACTIVO QUE CONTIENE ANTI-DC3 Y UN PRIMER MARCADOR DETECTABLE, Y UN SEGUNDO REACTIVO QUE TIENE UNA MEZCLA DE ANTI-DC16 Y ANTI-GP160 (LEU-19) MARCADOS CON UN SEGUNDO MARCADOR DETECTABLE, E IDENTIFICAR CELULAS QUE REACCIONAN CON LOS REACTIVOS, CON LO QUE LAS CELULAS QUE REACCIONAN CON EL PRIMER REACTIVO SE IDENTIFICAN COMO LINFOCITOS T, Y LAS CELULAS QUE REACCIONAN SOLO CON EL SEGUNDO REACTIVO SE IDENTIFICAN COMO CELULAS NK. LAS CELULAS QUE REACCIONAN CON AMBOS REACTIVOS SE IDENTIFICAN COMO UN UNICO SUBCONJUNTO DE LINFOCITOS T, ALGUNO DE LOS CUALES PUEDE ARBITRAR CITOLISIS LIBRE DE MHC.
ES89300107T 1988-01-06 1989-01-06 Identificacion de celulas nk y linfocitos t citotoxicos. Expired - Lifetime ES2053967T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/141,626 US4895796A (en) 1988-01-06 1988-01-06 Identification of NK cells and cytotoxic T lymphocytes

Publications (1)

Publication Number Publication Date
ES2053967T3 true ES2053967T3 (es) 1994-08-01

Family

ID=22496491

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89300107T Expired - Lifetime ES2053967T3 (es) 1988-01-06 1989-01-06 Identificacion de celulas nk y linfocitos t citotoxicos.

Country Status (6)

Country Link
US (1) US4895796A (es)
EP (1) EP0337586B1 (es)
JP (1) JP2644029B2 (es)
AT (1) ATE103391T1 (es)
DE (1) DE68914016T2 (es)
ES (1) ES2053967T3 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2666557B2 (ja) * 1990-10-15 1997-10-22 トヨタ自動車株式会社 エバポパージシステムの故障診断装置
US5340719A (en) * 1990-11-23 1994-08-23 Corporation Coulter Method and apparatus for optically screening microscopic cells
JPH04311664A (ja) * 1991-04-11 1992-11-04 Toyota Motor Corp 蒸発燃料回収装置
US5245973A (en) * 1991-04-18 1993-09-21 Toyota Jidosha Kabushiki Kaisha Failure detection device for evaporative fuel purge system
ES2051651B1 (es) * 1992-12-10 1995-01-01 Univ Salamanca Procedimiento para la cuantificacion simultanea, en una sola medicion, de los principales tipos de linfocitos humanos y sus subpoblaciones.
US5688690A (en) * 1994-09-16 1997-11-18 The Wistar Institute Of Anatomy And Biology Human cytotoxic lymphocyte signal transduction surface protein (P38) and monoclonal antibodies thereto
AU5870800A (en) * 1999-06-09 2000-12-28 Ljl Biosystems, Inc. Cell-signaling assays
AUPS159702A0 (en) * 2002-04-09 2002-05-16 Tong, Sun Wing Molecular detection and assay by magneto-thermal biochip micro-assay
CN116298275A (zh) * 2023-02-07 2023-06-23 广州市海珠区江海街社区卫生服务中心 噬血细胞性淋巴组织细胞增多症诊断标志物nk细胞亚群及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2953610T1 (de) * 1979-03-19 1981-04-23 Diagnostic Techn Int Inc Double tagged immunoassay
US4284412A (en) * 1979-07-13 1981-08-18 Ortho Diagnostics, Inc. Method and apparatus for automated identification and enumeration of specified blood cell subclasses
JPS5745454A (en) * 1980-09-02 1982-03-15 Fuji Photo Film Co Ltd Immunochemical measuring method for various minor components
US4599307A (en) * 1983-07-18 1986-07-08 Becton, Dickinson And Company Method for elimination of selected cell populations in analytic cytology
US4599304A (en) * 1983-10-07 1986-07-08 Becton, Dickinson And Company Method for monitoring activated cell subpopulations
US4772552A (en) * 1984-04-23 1988-09-20 Dana-Farber Cancer Institute, Inc. Monoclonal antibody which recognizes a 200-220 KD antigen on natural killer cells
US4727020A (en) * 1985-02-25 1988-02-23 Becton, Dickinson And Company Method for analysis of subpopulations of blood cells
CA1279008C (en) * 1985-10-11 1991-01-15 Smith Kline & French Canada Ltd. Methods and reagents for performing subset analysis
JPS62274260A (ja) * 1986-05-23 1987-11-28 Nichirei:Kk 新規多重免疫組織化学的染色法およびそれを用いた細胞染色用キツト

Also Published As

Publication number Publication date
EP0337586A2 (en) 1989-10-18
JPH026754A (ja) 1990-01-10
EP0337586A3 (en) 1990-10-31
DE68914016D1 (de) 1994-04-28
EP0337586B1 (en) 1994-03-23
US4895796A (en) 1990-01-23
ATE103391T1 (de) 1994-04-15
DE68914016T2 (de) 1994-08-04
JP2644029B2 (ja) 1997-08-25

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