ES2055104T3 - Un procedimiento para preparar un compuesto que tiene actividad antagonista de fap. - Google Patents
Un procedimiento para preparar un compuesto que tiene actividad antagonista de fap.Info
- Publication number
- ES2055104T3 ES2055104T3 ES89312361T ES89312361T ES2055104T3 ES 2055104 T3 ES2055104 T3 ES 2055104T3 ES 89312361 T ES89312361 T ES 89312361T ES 89312361 T ES89312361 T ES 89312361T ES 2055104 T3 ES2055104 T3 ES 2055104T3
- Authority
- ES
- Spain
- Prior art keywords
- fap
- preparing
- procedure
- compound
- antagonist activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 239000005557 antagonist Substances 0.000 title abstract 2
- HVAUUPRFYPCOCA-AREMUKBSSA-N 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCCOC[C@@H](OC(C)=O)COP([O-])(=O)OCC[N+](C)(C)C HVAUUPRFYPCOCA-AREMUKBSSA-N 0.000 abstract 1
- 241000233866 Fungi Species 0.000 abstract 1
- 241001503951 Phoma Species 0.000 abstract 1
- 241001207509 Phoma sp. Species 0.000 abstract 1
- 108010003541 Platelet Activating Factor Proteins 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 229930184946 phomactin Natural products 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/32—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by aldehydo- or ketonic radicals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP30027888 | 1988-11-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2055104T3 true ES2055104T3 (es) | 1994-08-16 |
Family
ID=17882866
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES89312361T Expired - Lifetime ES2055104T3 (es) | 1988-11-28 | 1989-11-28 | Un procedimiento para preparar un compuesto que tiene actividad antagonista de fap. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5151529A (de) |
| EP (1) | EP0371762B1 (de) |
| KR (1) | KR940004128B1 (de) |
| AT (1) | ATE88707T1 (de) |
| CA (1) | CA2003956A1 (de) |
| DE (1) | DE68906248T2 (de) |
| ES (1) | ES2055104T3 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0842291A4 (de) * | 1995-07-25 | 1998-11-11 | Merck & Co Inc | Inhibitoren der farnesyl-protein transferase |
| US5663193A (en) * | 1995-07-25 | 1997-09-02 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| JP4123106B2 (ja) | 2003-08-22 | 2008-07-23 | ソニー株式会社 | 有機el素子 |
-
1989
- 1989-11-27 CA CA002003956A patent/CA2003956A1/en not_active Abandoned
- 1989-11-28 DE DE8989312361T patent/DE68906248T2/de not_active Expired - Fee Related
- 1989-11-28 AT AT89312361T patent/ATE88707T1/de not_active IP Right Cessation
- 1989-11-28 EP EP89312361A patent/EP0371762B1/de not_active Expired - Lifetime
- 1989-11-28 ES ES89312361T patent/ES2055104T3/es not_active Expired - Lifetime
- 1989-11-28 KR KR1019890017327A patent/KR940004128B1/ko not_active Expired - Fee Related
-
1990
- 1990-10-10 US US07/596,580 patent/US5151529A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE68906248D1 (de) | 1993-06-03 |
| CA2003956A1 (en) | 1990-05-28 |
| EP0371762A3 (de) | 1991-03-20 |
| DE68906248T2 (de) | 1993-08-12 |
| US5151529A (en) | 1992-09-29 |
| KR940004128B1 (ko) | 1994-05-13 |
| EP0371762A2 (de) | 1990-06-06 |
| ATE88707T1 (de) | 1993-05-15 |
| KR900008048A (ko) | 1990-06-02 |
| EP0371762B1 (de) | 1993-04-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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