ES2055637T3 - Nuevos compuestos poli-yodados, procedimiento de preparacion, producto de contraste que los contiene. - Google Patents

Nuevos compuestos poli-yodados, procedimiento de preparacion, producto de contraste que los contiene.

Info

Publication number
ES2055637T3
ES2055637T3 ES92400485T ES92400485T ES2055637T3 ES 2055637 T3 ES2055637 T3 ES 2055637T3 ES 92400485 T ES92400485 T ES 92400485T ES 92400485 T ES92400485 T ES 92400485T ES 2055637 T3 ES2055637 T3 ES 2055637T3
Authority
ES
Spain
Prior art keywords
product containing
preparation procedure
contrast product
iodine compounds
new poly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92400485T
Other languages
English (en)
Inventor
Maryse Dugast-Zrihen
Dominique Meyer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guerbet SA
Original Assignee
Guerbet SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guerbet SA filed Critical Guerbet SA
Application granted granted Critical
Publication of ES2055637T3 publication Critical patent/ES2055637T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/16—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Pyrrole Compounds (AREA)
  • Liquid Crystal Substances (AREA)

Abstract

LA INVENCION SE REFIERE A NUEVOS COMPUESTOS POLIYODADOS DE FORMULA GENERAL (I): EN LA QUE R SUB 1, R SUB 2, R SUB 3, R SUB 4, R SUB 5, R SUB 6, R SUB 7, R SUB 8, R SUB 9 Y R SUB 10 IDENTICOS O DIFERENTES ENTRE SI SON ELEGIDOS ENTRE UN ATOMO DE YODO, UN GRUPO DE FORMULA: Y UN GRUPO DE FORMULA SIEMPRE QUE AL MENOS DOS GRUPOS DE ENTRE R SUB 1, R SUB 2, R SUB 3, R SUB 4 , R SUB 5, R SUB 6, R SUB 7, R SUB 8, R SUB 9 Y R SUB 10 REPRESENTEN UN ATOMO DE YODO, UTILIZABLES EN LOS PRODUCTOS DE CONTRASTE PARA LA RADIOGRAFIA. LA INVENCION TAMBIEN SE REFIERE A UN PROCESO DE PREPARACION DE ESTOS COMPUESTOS ASI COMO A UN PRODUCTO DE CONTRASTE QUE LOS CONTIENE.
ES92400485T 1991-02-25 1992-02-25 Nuevos compuestos poli-yodados, procedimiento de preparacion, producto de contraste que los contiene. Expired - Lifetime ES2055637T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR919102226A FR2673180B1 (fr) 1991-02-25 1991-02-25 Nouveaux composes non ioniques poly-iodes, procede de preparation, produit de contraste les contenant.

Publications (1)

Publication Number Publication Date
ES2055637T3 true ES2055637T3 (es) 1994-08-16

Family

ID=9410062

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92400485T Expired - Lifetime ES2055637T3 (es) 1991-02-25 1992-02-25 Nuevos compuestos poli-yodados, procedimiento de preparacion, producto de contraste que los contiene.

Country Status (19)

Country Link
US (1) US5616798A (es)
EP (1) EP0501875B1 (es)
JP (1) JPH06505267A (es)
AT (1) ATE106864T1 (es)
AU (1) AU654341B2 (es)
CA (1) CA2104786A1 (es)
CZ (1) CZ173693A3 (es)
DE (1) DE69200168T2 (es)
DK (1) DK0501875T3 (es)
ES (1) ES2055637T3 (es)
FR (1) FR2673180B1 (es)
IE (1) IE66594B1 (es)
IL (1) IL101064A0 (es)
MX (1) MX9200790A (es)
NO (1) NO932992L (es)
NZ (1) NZ241725A (es)
SK (1) SK89393A3 (es)
WO (1) WO1992014695A1 (es)
ZA (1) ZA921369B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09505813A (ja) * 1993-12-03 1997-06-10 ブラッコ エッセ．ピ．ア． ビフェニル沃素化誘導体及びその診断用途
ATE181547T1 (de) * 1994-09-22 1999-07-15 Guerbet Sa Iodo-verbindungen, ihre herstellung und verwendung als kontrastmittel für röntgen- radiologie
GB9419206D0 (en) * 1994-09-23 1994-11-09 Nycomed Innovation Ab Contrast media
GB9419203D0 (en) * 1994-09-23 1994-11-09 Nycomed Innovation Ab Contrast media
US6310243B1 (en) * 1994-09-23 2001-10-30 Nycomed Imaging As Iodinated x-ray contrast media
IT1271134B (it) * 1994-12-01 1997-05-26 Bracco Spa Derivati iodurati del bifenile e loro impiego diagnostico
US5575905A (en) * 1995-05-24 1996-11-19 Nycomed Imaging As Iodination process
US6265610B1 (en) * 1999-01-12 2001-07-24 The University Of North Carolina At Chapel Hill Contrast media for angiography
ATE298320T1 (de) * 1999-04-30 2005-07-15 Amersham Health As Kontrastmittel
US6981817B2 (en) * 2003-07-17 2006-01-03 Braverman Josef J Base unit for road delineating devices
DE102007058220A1 (de) 2007-12-03 2009-06-04 Bayer Schering Pharma Aktiengesellschaft Dimere macrocyclisch substituierte Benzolderivate
EP2093206A1 (en) 2008-02-20 2009-08-26 BRACCO IMAGING S.p.A. Process for the iodination of aromatic compounds
EP2243767A1 (en) 2009-04-21 2010-10-27 Bracco Imaging S.p.A Process for the iodination of aromatic compounds
SG177308A1 (en) * 2009-06-22 2012-02-28 Hoffmann La Roche Novel biphenyl and phenyl-pyridine amides
JP5661762B2 (ja) 2009-07-07 2015-01-28 ブラッコ・イメージング・ソシエタ・ペル・アチオニＢｒａｃｃｏ Ｉｍａｇｉｎｇ Ｓ．Ｐ．Ａ． ヨウ素化剤の製造方法
EP2394984A1 (en) 2010-06-10 2011-12-14 Bracco Imaging S.p.A Process for the iodination of phenolic derivatives
EP2700645A4 (en) 2011-04-20 2014-09-24 Kemphys Ltd SILICONE-CONTAINING CARBOXYLENE DERIVATIVE
WO2017165841A1 (en) 2016-03-25 2017-09-28 Nanoprobes, Inc. Iodine-based particles

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4102924A (en) * 1973-10-25 1978-07-25 Bayer Aktiengesellschaft Process for the preparation of diaryl compounds
IT1207226B (it) * 1979-08-09 1989-05-17 Bracco Ind Chimica Spa Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono.
FR2541676A1 (fr) * 1983-02-25 1984-08-31 Guerbet Sa Composes non-ioniques a structures benzenique iodee ou bromee et produits opacifiants en contenant
DE3429949A1 (de) * 1984-08-10 1986-02-20 Schering AG, 1000 Berlin und 4709 Bergkamen Neue nicht -ionische 2,4,6-trijod-isophthalsaeure-bis-amide, verfahren zu ihrer herstellung und ihre verwendung als roentgenkontrastmittel
DE3731542A1 (de) * 1987-09-17 1989-03-30 Schering Ag Neue dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6-triiod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel
IL90326A (en) * 1988-06-02 1993-05-13 Guerbet Sa Non-ionic triiodobenzene compounds and contrast media containing them
US5232685A (en) * 1989-11-03 1993-08-03 Schering Aktiengesellschaft Nonionic x-ray contrast medium with high iodine content

Also Published As

Publication number Publication date
IE920585A1 (en) 1992-08-26
IE66594B1 (en) 1996-01-24
DE69200168T2 (de) 1994-10-20
EP0501875A1 (fr) 1992-09-02
ATE106864T1 (de) 1994-06-15
EP0501875B1 (fr) 1994-06-08
FR2673180B1 (fr) 1994-03-04
CA2104786A1 (fr) 1992-08-26
NZ241725A (en) 1994-10-26
NO932992D0 (no) 1993-08-23
NO932992L (no) 1993-10-25
AU654341B2 (en) 1994-11-03
JPH06505267A (ja) 1994-06-16
AU1413592A (en) 1992-09-15
DK0501875T3 (da) 1994-10-10
US5616798A (en) 1997-04-01
FR2673180A1 (fr) 1992-08-28
ZA921369B (en) 1993-08-25
MX9200790A (es) 1992-08-01
IL101064A0 (en) 1992-11-15
DE69200168D1 (de) 1994-07-14
SK89393A3 (en) 1994-04-06
CZ173693A3 (en) 1994-02-16
WO1992014695A1 (fr) 1992-09-03

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