ES2055925T3 - Derivados de la 9-fluor-prostaglandina, procedimiento para su obtencion y su uso farmaceutico. - Google Patents

Derivados de la 9-fluor-prostaglandina, procedimiento para su obtencion y su uso farmaceutico.

Info

Publication number
ES2055925T3
ES2055925T3 ES90917919T ES90917919T ES2055925T3 ES 2055925 T3 ES2055925 T3 ES 2055925T3 ES 90917919 T ES90917919 T ES 90917919T ES 90917919 T ES90917919 T ES 90917919T ES 2055925 T3 ES2055925 T3 ES 2055925T3
Authority
ES
Spain
Prior art keywords
fluor
pharmaceutical use
prostaglandina
derivatives
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90917919T
Other languages
English (en)
Inventor
Ulrich Klar
Hartmut Rehwinkel
Helmut Vorbruggen
Karl-Heinz Thierauch
Claus-Steffen Sturzebecher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of ES2055925T3 publication Critical patent/ES2055925T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

LA INVENCION SE REFIERE A UN DERIVADO DE 9-FLUOR DE PROSTAGLANDINA DE FORMULA (I) Y SUS SALES FISIOLOGICAS CON BASES TOLERABLES. TRATA DE UN PROCEDIMIENTO PARA LA PRODUCCION DE UN COMPUESTO DE FORMULA (I) Y DESCRIBE LA APLICACION FARMACEUTICA DE (I), Y SE REFIERE A LOS (ALFA), (BETA) O GAMMA-CICLODEXTRINACLATRATOS Y A COMPUESTOS DE FORMULA (I) ENCAPSULADOS CON LIPOSOMAS.
ES90917919T 1989-07-14 1990-07-13 Derivados de la 9-fluor-prostaglandina, procedimiento para su obtencion y su uso farmaceutico. Expired - Lifetime ES2055925T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3923797A DE3923797A1 (de) 1989-07-14 1989-07-14 9-fluor-prostaglandin-derivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung

Publications (1)

Publication Number Publication Date
ES2055925T3 true ES2055925T3 (es) 1994-09-01

Family

ID=6385316

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90917919T Expired - Lifetime ES2055925T3 (es) 1989-07-14 1990-07-13 Derivados de la 9-fluor-prostaglandina, procedimiento para su obtencion y su uso farmaceutico.

Country Status (8)

Country Link
EP (1) EP0434833B1 (es)
JP (1) JPH04502329A (es)
AT (1) ATE106076T1 (es)
CA (1) CA2036386A1 (es)
DE (2) DE3923797A1 (es)
DK (1) DK0434833T3 (es)
ES (1) ES2055925T3 (es)
WO (1) WO1991001302A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4024347A1 (de) * 1990-07-27 1992-01-30 Schering Ag Cyclopentanderivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung
US5972991A (en) 1992-09-21 1999-10-26 Allergan Cyclopentane heptan(ene) oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
WO1994008585A1 (en) * 1992-10-13 1994-04-28 Alcon Laboratories, Inc. Combinations of prostaglandins and clonidine derivatives for the treatment of glaucoma
US6294563B1 (en) 1994-10-27 2001-09-25 Allergan Sales, Inc. Combinations of prostaglandins and brimonidine or derivatives thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3126924A1 (de) * 1981-07-03 1983-01-20 Schering Ag, 1000 Berlin Und 4619 Bergkamen 9-fluor-prostaglandinderivate, verfahren zur herstellung und verwendung als arzneimittel
DE3504044A1 (de) * 1985-02-04 1986-08-07 Schering AG, Berlin und Bergkamen, 1000 Berlin 9-halogenprostaglandin-clathrate und ihre verwendung als arzneimittel
CA1322197C (en) * 1987-07-17 1993-09-14 Bernd Buchmann 9-halogen-(z) prostaglandin derivatives, process for their production and their use as pharmaceutical agents

Also Published As

Publication number Publication date
EP0434833B1 (de) 1994-05-25
ATE106076T1 (de) 1994-06-15
DE59005819D1 (de) 1994-06-30
DE3923797A1 (de) 1991-01-24
JPH04502329A (ja) 1992-04-23
WO1991001302A1 (de) 1991-02-07
DK0434833T3 (da) 1994-09-19
CA2036386A1 (en) 1991-01-15
EP0434833A1 (de) 1991-07-03

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