ES2056121T3 - 3-arilcarbamoil-5-aminometil-oxazolidinas asi como sus sales con acidos farmaceuticamente compatibles. - Google Patents

3-arilcarbamoil-5-aminometil-oxazolidinas asi como sus sales con acidos farmaceuticamente compatibles.

Info

Publication number
ES2056121T3
ES2056121T3 ES88450019T ES88450019T ES2056121T3 ES 2056121 T3 ES2056121 T3 ES 2056121T3 ES 88450019 T ES88450019 T ES 88450019T ES 88450019 T ES88450019 T ES 88450019T ES 2056121 T3 ES2056121 T3 ES 2056121T3
Authority
ES
Spain
Prior art keywords
group
oxazolidinas
arilcarbamoil
aminometil
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88450019T
Other languages
English (en)
Inventor
Christian Jarry
Jean-Jacques Bosc
Emmanuel Panconi
Bernard Vaugien
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cortial SA
Original Assignee
Cortial SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8706890A external-priority patent/FR2615190B1/fr
Application filed by Cortial SA filed Critical Cortial SA
Application granted granted Critical
Publication of ES2056121T3 publication Critical patent/ES2056121T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/26—Oxygen atoms attached in position 2 with hetero atoms or acyl radicals directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/28—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A NUEVAS ARILCARBAMOIL-3 AMINOMETIL-5 OXAZOLIDINAS ASI COMO SUS SALES CON ACIDOS FARMACEUTICAMENTE COMPATIBLES. LOS COMPUESTOS DE LA INVENCION TIENEN POR FORMULA GENERAL LA ESTRUCTURA (I). EL GRUPO R1 ES UN OXIGENO O UN GRUPO NH, EL GRUPO R2 ES UN OXIGENO O UN AZUFRE, EL GRUPO AR1 ES UN GRUPO FENIL SUSTITUIDO O NO POR UNO O VARIOS GRUPOS ELEGIDOS DE ENTRE GRUPOS ALQUIL INFERIORES DE C1 A C4, HALOGENO, CLORO, BROMO, FLUOR O UN GRUPO TRIFLUORMETIL O UN GRUPO METOXI, EL GRUPO AR1 PUEDE SER IGUALMENTE UN GRUPO PIRIDIL O UN GRUPO PIRIMIDIL, EL GRUPO AR2 ES UN GRUPO FENIL SUSTITUIDO O NO POR UNO O VARIOS GRUPOS ELEGIDOS DE ENTRE GRUPOS ALQUIL INFERIORES O NO POR UNO O VARIOS GRUPOS ALQUIL INFERIORES DE C1 A C4, HALOGENO, CLORO, BROMO, FLUOR, IODO. LOS COMPUESTOS DE LA INVENCION SE USAN EN EL TRATAMIENTO DE LA HIPERTENSION Y CANDIDIOSIS.
ES88450019T 1987-05-14 1988-05-09 3-arilcarbamoil-5-aminometil-oxazolidinas asi como sus sales con acidos farmaceuticamente compatibles. Expired - Lifetime ES2056121T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8706890A FR2615190B1 (fr) 1987-05-14 1987-05-14 Nouvelles arylcarbamoyl-3 aminomethyl-5 oxazolidines ainsi que leurs sels avec des acides pharmaceutiquement compatibles, leur methode de preparation et leur application pharmaceutique
FR888806253A FR2631029B2 (fr) 1987-05-14 1988-05-05 Nouvelles arylcarbamoyl-3 aminomethyl-5 oxazolidines ainsi que leurs sels avec des acides pharmacologiquement compatibles

Publications (1)

Publication Number Publication Date
ES2056121T3 true ES2056121T3 (es) 1994-10-01

Family

ID=26225986

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88450019T Expired - Lifetime ES2056121T3 (es) 1987-05-14 1988-05-09 3-arilcarbamoil-5-aminometil-oxazolidinas asi como sus sales con acidos farmaceuticamente compatibles.

Country Status (5)

Country Link
EP (1) EP0294307B1 (es)
AT (1) ATE107637T1 (es)
DE (1) DE3850304T2 (es)
ES (1) ES2056121T3 (es)
FR (1) FR2631029B2 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19504954A1 (de) * 1995-02-15 1996-08-22 Merck Patent Gmbh Adhäsionsrezeptor-Antagonisten

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2226165A2 (en) * 1973-04-19 1974-11-15 Delalande Sa 3-Aminocarbonyl-5-phenyl-2-oxazolidones - with anticonvulsant, tranquillizing muscle relaxant, antiinflammatory and hypnotic activity
NZ194913A (en) * 1979-10-03 1983-11-18 Nippon Soda Co Trans-4,5-disubstituted-3-substituted (thio)carbamoyl-(oxazolidin or thiazolidin)-2-(thio)ones
PT77429B (fr) * 1982-10-05 1986-02-27 Cortial Procede pour preparer de nouvelles n-(amino-methyl-5 oxazolin-2 yl-2)n'-phenylurees et de compositions les contenant

Also Published As

Publication number Publication date
FR2631029A2 (fr) 1989-11-10
FR2631029B2 (fr) 1991-04-05
DE3850304T2 (de) 1994-10-27
EP0294307B1 (fr) 1994-06-22
ATE107637T1 (de) 1994-07-15
EP0294307A1 (fr) 1988-12-07
DE3850304D1 (de) 1994-07-28

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