ATE107637T1 - 3-arylcarbamoyl-5-aminomethyl-oxazolidine sowie deren salz mit pharmakologisch verträglichen säuren. - Google Patents
3-arylcarbamoyl-5-aminomethyl-oxazolidine sowie deren salz mit pharmakologisch verträglichen säuren.Info
- Publication number
- ATE107637T1 ATE107637T1 AT88450019T AT88450019T ATE107637T1 AT E107637 T1 ATE107637 T1 AT E107637T1 AT 88450019 T AT88450019 T AT 88450019T AT 88450019 T AT88450019 T AT 88450019T AT E107637 T1 ATE107637 T1 AT E107637T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- arylcarbamoyl
- oxazolidine
- aminomethyl
- salts
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 150000007513 acids Chemical class 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 241000222122 Candida albicans Species 0.000 abstract 1
- 206010007134 Candida infections Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Chemical group 0.000 abstract 1
- MHHJTXLHRIXMMC-UHFFFAOYSA-N [F].[Cl].[Br] Chemical compound [F].[Cl].[Br] MHHJTXLHRIXMMC-UHFFFAOYSA-N 0.000 abstract 1
- IDOKWIROLYYEIB-UHFFFAOYSA-N [I].[Br].[Cl].[F] Chemical compound [I].[Br].[Cl].[F] IDOKWIROLYYEIB-UHFFFAOYSA-N 0.000 abstract 1
- 201000003984 candidiasis Diseases 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 125000000714 pyrimidinyl group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- C07D263/26—Oxygen atoms attached in position 2 with hetero atoms or acyl radicals directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/28—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8706890A FR2615190B1 (fr) | 1987-05-14 | 1987-05-14 | Nouvelles arylcarbamoyl-3 aminomethyl-5 oxazolidines ainsi que leurs sels avec des acides pharmaceutiquement compatibles, leur methode de preparation et leur application pharmaceutique |
| FR888806253A FR2631029B2 (fr) | 1987-05-14 | 1988-05-05 | Nouvelles arylcarbamoyl-3 aminomethyl-5 oxazolidines ainsi que leurs sels avec des acides pharmacologiquement compatibles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE107637T1 true ATE107637T1 (de) | 1994-07-15 |
Family
ID=26225986
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88450019T ATE107637T1 (de) | 1987-05-14 | 1988-05-09 | 3-arylcarbamoyl-5-aminomethyl-oxazolidine sowie deren salz mit pharmakologisch verträglichen säuren. |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0294307B1 (de) |
| AT (1) | ATE107637T1 (de) |
| DE (1) | DE3850304T2 (de) |
| ES (1) | ES2056121T3 (de) |
| FR (1) | FR2631029B2 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19504954A1 (de) * | 1995-02-15 | 1996-08-22 | Merck Patent Gmbh | Adhäsionsrezeptor-Antagonisten |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2226165A2 (en) * | 1973-04-19 | 1974-11-15 | Delalande Sa | 3-Aminocarbonyl-5-phenyl-2-oxazolidones - with anticonvulsant, tranquillizing muscle relaxant, antiinflammatory and hypnotic activity |
| IL61016A (en) * | 1979-10-03 | 1984-02-29 | Nippon Soda Co | 3-carboxamide(or carbothiamide)derivatives of oxazolidine and thiazolidine-2-one(or 2-thione),their preparation and acaricidal compositions containing them |
| PT77429B (fr) * | 1982-10-05 | 1986-02-27 | Cortial | Procede pour preparer de nouvelles n-(amino-methyl-5 oxazolin-2 yl-2)n'-phenylurees et de compositions les contenant |
-
1988
- 1988-05-05 FR FR888806253A patent/FR2631029B2/fr not_active Expired - Lifetime
- 1988-05-09 EP EP88450019A patent/EP0294307B1/de not_active Expired - Lifetime
- 1988-05-09 AT AT88450019T patent/ATE107637T1/de not_active IP Right Cessation
- 1988-05-09 ES ES88450019T patent/ES2056121T3/es not_active Expired - Lifetime
- 1988-05-09 DE DE3850304T patent/DE3850304T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0294307A1 (de) | 1988-12-07 |
| FR2631029A2 (fr) | 1989-11-10 |
| DE3850304D1 (de) | 1994-07-28 |
| ES2056121T3 (es) | 1994-10-01 |
| FR2631029B2 (fr) | 1991-04-05 |
| DE3850304T2 (de) | 1994-10-27 |
| EP0294307B1 (de) | 1994-06-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |