|
US6309640B1
(en)
|
1981-09-08 |
2001-10-30 |
The Rockefeller University |
Lipoprotein lipase suppression by endotoxin-induced mediator (shock assay)
|
|
US6419927B1
(en)
|
1981-09-08 |
2002-07-16 |
Anthony Cerami |
Method for reducing adverse effects of a human 70kDa mediator which results from endotoxin stimulation of macrophages
|
|
US5700466A
(en)
*
|
1981-09-08 |
1997-12-23 |
The Rockefeller University |
Method of ameliorating or preventing septic shock using a monoclonal antibody specific to cachectin/tumor necrosis factor
|
|
GB2233559B
(en)
*
|
1988-03-11 |
1992-03-04 |
Celltech Ltd |
Antibodies for use in antilymphocyte antibody therapy
|
|
DE3823804A1
(de)
*
|
1988-07-14 |
1990-01-18 |
Basf Ag |
Neutralisation der in vitro und in vivo toxischen eigenschaften von tnf-(alpha) durch monoklonale antikoerper und den davon abgeleiteten fragmenten
|
|
NZ229922A
(en)
*
|
1988-07-18 |
1992-04-28 |
Chiron Corp |
Monoclonal antibodies specifically binding cachectin (tumor necrosis factor) and compositions
|
|
WO1990001950A1
(en)
*
|
1988-08-19 |
1990-03-08 |
Celltech Limited |
Pharmaceutical products for anti-neoplastic therapy
|
|
DE69027121T3
(de)
†
|
1989-08-07 |
2001-08-30 |
Peptech Ltd., Dee Why |
Bindeligande für tumornekrosisfaktor
|
|
US5959087A
(en)
*
|
1989-08-07 |
1999-09-28 |
Peptide Technology, Ltd. |
Tumour necrosis factor binding ligands
|
|
US20030225254A1
(en)
*
|
1989-08-07 |
2003-12-04 |
Rathjen Deborah Ann |
Tumour necrosis factor binding ligands
|
|
US5998378A
(en)
*
|
1989-08-16 |
1999-12-07 |
Chiron Corporation |
Compositions for the inhibition of TNF hormone formation and uses thereof
|
|
US6586222B1
(en)
|
1989-08-16 |
2003-07-01 |
Chiron Corporation |
Recombinant PR-3 and compositions thereof
|
|
JPH05501351A
(ja)
*
|
1989-08-16 |
1993-03-18 |
カイロン コーポレイション |
プロホルモンタンパク質に対する開裂部位阻止抗体及びその使用
|
|
US5843693A
(en)
*
|
1989-08-16 |
1998-12-01 |
Chiron Corporation |
Assay method for screening for inhibitors of proTNF conversion
|
|
GB8921123D0
(en)
*
|
1989-09-19 |
1989-11-08 |
Millar Ann B |
Treatment of ards
|
|
US6713610B1
(en)
*
|
1990-01-12 |
2004-03-30 |
Raju Kucherlapati |
Human antibodies derived from immunized xenomice
|
|
EP1097945B1
(en)
*
|
1991-03-18 |
2007-07-04 |
New York University |
Monoclonal and chimeric antibody specific for human tumor necrosis factor
|
|
US5919452A
(en)
*
|
1991-03-18 |
1999-07-06 |
New York University |
Methods of treating TNFα-mediated disease using chimeric anti-TNF antibodies
|
|
US7192584B2
(en)
*
|
1991-03-18 |
2007-03-20 |
Centocor, Inc. |
Methods of treating psoriasis with anti-TNF antibodies
|
|
US6277969B1
(en)
*
|
1991-03-18 |
2001-08-21 |
New York University |
Anti-TNF antibodies and peptides of human tumor necrosis factor
|
|
US20040120952A1
(en)
*
|
2000-08-07 |
2004-06-24 |
Centocor, Inc |
Anti-TNF antibodies and peptides of human tumor necrosis factor
|
|
US6284471B1
(en)
*
|
1991-03-18 |
2001-09-04 |
New York University Medical Center |
Anti-TNFa antibodies and assays employing anti-TNFa antibodies
|
|
DK0585705T3
(da)
*
|
1992-08-28 |
1999-07-26 |
Bayer Ag |
Anvendelse af monoklone anti-TNF-antistoffer til behandling af bakteriel meningitis
|
|
US20050260201A1
(en)
*
|
1993-01-29 |
2005-11-24 |
Centocor, Inc. |
Methods of treating rheumatoid arthritis using anti-TNF receptor fusion proteins
|
|
US5626843A
(en)
*
|
1993-02-26 |
1997-05-06 |
Advanced Biotherapy Concepts, Inc. |
Treatment of autoimmune diseases, including AIDS, by removel of interferons, TNFs and receptors therefor
|
|
US5888511A
(en)
*
|
1993-02-26 |
1999-03-30 |
Advanced Biotherapy Concepts, Inc. |
Treatment of autoimmune diseases, including AIDS
|
|
DE4409513C1
(de)
*
|
1994-02-07 |
1995-10-19 |
Knoll Ag |
Verwendung von anti-TNF-Antikörpern als Arzneimittel zur Behandlung von Erkrankungen mit einem erhöhten Interleukin-6 Serumspiegel
|
|
NZ278607A
(en)
*
|
1994-02-07 |
1999-05-28 |
Knoll Ag |
Use of tnf antagonists for treating disorders involving elevated serum levels of il-6 wherein the serum levels are 500pg/ml or above
|
|
CA2185162A1
(en)
|
1994-03-07 |
1995-09-14 |
Robert F. Halenback (Deceased) |
Compositions for the inhibition of tnf formation and uses thereof
|
|
US6090382A
(en)
|
1996-02-09 |
2000-07-18 |
Basf Aktiengesellschaft |
Human antibodies that bind human TNFα
|
|
DK0929578T3
(da)
|
1996-02-09 |
2003-08-25 |
Abbott Lab Bermuda Ltd |
Humane antistoffer, der binder human TNFalfa
|
|
US7608262B2
(en)
*
|
1996-02-16 |
2009-10-27 |
The Kennedy Institute Of Rheumatology |
Methods of preventing or treating thrombosis with tumor necrosis factor antagonists
|
|
EP1500329B1
(en)
*
|
1996-12-03 |
2012-03-21 |
Amgen Fremont Inc. |
Human antibodies that specifically bind human TNF alpha
|
|
US20020031513A1
(en)
*
|
1997-11-24 |
2002-03-14 |
Shamir Leibovitz |
Method and pharmaceutical composition for inhibiting premature rapture of fetal membranes, ripening of uterine cervix and preterm labor in mammals
|
|
DK1159003T3
(da)
*
|
1999-03-02 |
2011-02-07 |
Centocor Inc |
Anti-tnfalfa-antistoffer til terapi af steroid-resistent astma
|
|
KR100672892B1
(ko)
*
|
1999-03-18 |
2007-01-23 |
셀진 코오퍼레이션 |
치환된 1-옥소- 및 1,3-디옥소이소인돌린스 및 염증성사이토킨 수치를 감소시키기 위한 약학적 조성물로서의이들의 사용
|
|
EP1227847A2
(en)
*
|
1999-10-06 |
2002-08-07 |
Basf Aktiengesellschaft |
Inhibitors of the endothelin signalling pathway and alphavbeta3 integrin receptor antagonists for combination therapy
|
|
US6902734B2
(en)
|
2000-08-07 |
2005-06-07 |
Centocor, Inc. |
Anti-IL-12 antibodies and compositions thereof
|
|
US20090081234A1
(en)
*
|
2000-08-07 |
2009-03-26 |
George Heavner |
Anti-tnf antibodies, compositions, methods and uses for treatment of depression and related conditions
|
|
US7288390B2
(en)
|
2000-08-07 |
2007-10-30 |
Centocor, Inc. |
Anti-dual integrin antibodies, compositions, methods and uses
|
|
UA81743C2
(uk)
|
2000-08-07 |
2008-02-11 |
Центокор, Инк. |
МОНОКЛОНАЛЬНЕ АНТИТІЛО ЛЮДИНИ, ЩО СПЕЦИФІЧНО ЗВ'ЯЗУЄТЬСЯ З ФАКТОРОМ НЕКРОЗУ ПУХЛИН АЛЬФА (ФНПα), ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ, ЩО ЙОГО МІСТИТЬ, ТА СПОСІБ ЛІКУВАННЯ РЕВМАТОЇДНОГО АРТРИТУ
|
|
US20050249735A1
(en)
*
|
2000-08-07 |
2005-11-10 |
Centocor, Inc. |
Methods of treating ankylosing spondylitis using anti-TNF antibodies and peptides of human tumor necrosis factor
|
|
US20060018907A1
(en)
*
|
2000-08-07 |
2006-01-26 |
Centocor, Inc. |
Anti-TNF antibodies and peptides of human tumor necrosis factor
|
|
US20110195063A1
(en)
*
|
2000-08-07 |
2011-08-11 |
Centocor, Inc. |
Methods of Treating Ankylosing Spondylitis Using Anti-TNF Antibodies and Peptides of Human Tumor Necrosis Factor
|
|
EP1372720A4
(en)
*
|
2001-03-02 |
2006-07-26 |
Medimmune Inc |
PREVENTING OR TREATING INFLAMMATORY OR AUTOIMMUNE DISORDERS BY ADMINISTERING ANTAGONISTS OF INTEGRIN ALPHA V BETA 3
|
|
CA2817619A1
(en)
|
2001-06-08 |
2002-12-08 |
Abbott Laboratories (Bermuda) Ltd. |
Methods of administering anti-tnf.alpha. antibodies
|
|
TWI334439B
(en)
|
2001-08-01 |
2010-12-11 |
Centocor Inc |
Anti-tnf antibodies, compositions, methods and uses
|
|
US7371383B2
(en)
*
|
2002-04-12 |
2008-05-13 |
Medimmune, Inc. |
Recombinant anti-interleukin-9 antibodies
|
|
US20030206898A1
(en)
|
2002-04-26 |
2003-11-06 |
Steven Fischkoff |
Use of anti-TNFalpha antibodies and another drug
|
|
US20040009172A1
(en)
*
|
2002-04-26 |
2004-01-15 |
Steven Fischkoff |
Use of anti-TNFalpha antibodies and another drug
|
|
AU2003280130B2
(en)
|
2002-06-28 |
2009-06-11 |
Centocor, Inc. |
Mammalian CH1 deleted mimetibodies, compositions, methods and uses
|
|
US20040219142A1
(en)
|
2002-07-19 |
2004-11-04 |
Abbott Laboratories S.A. |
Treatment of skin and nail disorders using TNFalpha inhibitors
|
|
US20040033228A1
(en)
|
2002-08-16 |
2004-02-19 |
Hans-Juergen Krause |
Formulation of human antibodies for treating TNF-alpha associated disorders
|
|
MY150740A
(en)
|
2002-10-24 |
2014-02-28 |
Abbvie Biotechnology Ltd |
Low dose methods for treating disorders in which tnf? activity is detrimental
|
|
DE60333228D1
(de)
|
2002-12-02 |
2010-08-12 |
Amgen Fremont Inc |
Gegen den tumor nekrose faktor gerichtete antikörper und deren verwendungen
|
|
US7101978B2
(en)
*
|
2003-01-08 |
2006-09-05 |
Applied Molecular Evolution |
TNF-α binding molecules
|
|
JP4764818B2
(ja)
|
2003-04-11 |
2011-09-07 |
メディミューン,エルエルシー |
組換えil−9抗体およびその使用
|
|
US7429378B2
(en)
*
|
2003-05-13 |
2008-09-30 |
Depuy Spine, Inc. |
Transdiscal administration of high affinity anti-MMP inhibitors
|
|
US7553827B2
(en)
*
|
2003-08-13 |
2009-06-30 |
Depuy Spine, Inc. |
Transdiscal administration of cycline compounds
|
|
US7344716B2
(en)
*
|
2003-05-13 |
2008-03-18 |
Depuy Spine, Inc. |
Transdiscal administration of specific inhibitors of pro-inflammatory cytokines
|
|
US20040229878A1
(en)
*
|
2003-05-13 |
2004-11-18 |
Depuy Spine, Inc. |
Transdiscal administration of specific inhibitors of P38 kinase
|
|
US8273347B2
(en)
|
2003-05-13 |
2012-09-25 |
Depuy Spine, Inc. |
Autologous treatment of degenerated disc with cells
|
|
BRPI0410331A
(pt)
|
2003-05-13 |
2006-05-30 |
Depuy Spine Inc |
método para tratar doença de disco degenerativa
|
|
US8361467B2
(en)
*
|
2003-07-30 |
2013-01-29 |
Depuy Spine, Inc. |
Trans-capsular administration of high specificity cytokine inhibitors into orthopedic joints
|
|
UA89481C2
(uk)
|
2003-09-30 |
2010-02-10 |
Центокор, Инк. |
Еритропоетинові міметичні шарнірно-серцевинні міметитіла людини, композиції, способи та застосування
|
|
US8895540B2
(en)
*
|
2003-11-26 |
2014-11-25 |
DePuy Synthes Products, LLC |
Local intraosseous administration of bone forming agents and anti-resorptive agents, and devices therefor
|
|
US7435799B2
(en)
*
|
2004-01-08 |
2008-10-14 |
Applied Molecular Evolution |
TNF-α binding molecules
|
|
JP2008537873A
(ja)
*
|
2004-03-31 |
2008-10-02 |
セントカー・インコーポレーテツド |
ヒトglp−1ミメティボディ、組成物、方法および用途
|
|
TWI439284B
(zh)
|
2004-04-09 |
2014-06-01 |
艾伯維生物技術有限責任公司 |
用於治療TNFα相關失調症之多重可變劑量療法
|
|
US7351739B2
(en)
*
|
2004-04-30 |
2008-04-01 |
Wellgen, Inc. |
Bioactive compounds and methods of uses thereof
|
|
GB0414054D0
(en)
|
2004-06-23 |
2004-07-28 |
Owen Mumford Ltd |
Improvements relating to automatic injection devices
|
|
US7393662B2
(en)
*
|
2004-09-03 |
2008-07-01 |
Centocor, Inc. |
Human EPO mimetic hinge core mimetibodies, compositions, methods and uses
|
|
US20060083741A1
(en)
*
|
2004-10-08 |
2006-04-20 |
Hoffman Rebecca S |
Treatment of respiratory syncytial virus (RSV) infection
|
|
US20060121042A1
(en)
|
2004-10-27 |
2006-06-08 |
Medimmune, Inc. |
Modulation of antibody specificity by tailoring the affinity to cognate antigens
|
|
PE20061324A1
(es)
|
2005-04-29 |
2007-01-15 |
Centocor Inc |
Anticuerpos anti-il-6, composiciones, metodos y usos
|
|
CN102961746B
(zh)
|
2005-05-16 |
2016-06-15 |
艾伯维生物技术有限公司 |
TNFα抑制剂治疗腐蚀性多关节炎的用途
|
|
AU2006265002B2
(en)
|
2005-06-30 |
2012-09-20 |
Centocor, Inc. |
Anti-IL-23 antibodies, compositions, methods and uses
|
|
DK1915620T3
(da)
*
|
2005-08-02 |
2010-10-04 |
Xbiotech Inc |
Diagnose, behandling og prævention af vaskulære sygdomme ved hjælp af IL-1alpha-autoantistoffer
|
|
US20070041905A1
(en)
*
|
2005-08-19 |
2007-02-22 |
Hoffman Rebecca S |
Method of treating depression using a TNF-alpha antibody
|
|
WO2007025977A2
(en)
|
2005-08-30 |
2007-03-08 |
Actogenix Nv |
Anti-tnf alpha producing lactic acid bacteria for the treatment of chronic enterocolitis
|
|
NZ567286A
(en)
|
2005-11-01 |
2012-03-30 |
Abbott Biotechnolgy Ltd |
Methods and compositions for diagnosing ankylosing spondylitis using biomarkers
|
|
SI1971366T1
(sl)
|
2005-12-29 |
2014-10-30 |
Janssen Biotech, Inc. |
Humana protitelesa anti-il-23, sestavki, postopki in uporabe
|
|
KR20140071452A
(ko)
*
|
2006-04-05 |
2014-06-11 |
애브비 바이오테크놀로지 리미티드 |
항체 정제
|
|
US9605064B2
(en)
|
2006-04-10 |
2017-03-28 |
Abbvie Biotechnology Ltd |
Methods and compositions for treatment of skin disorders
|
|
US9399061B2
(en)
*
|
2006-04-10 |
2016-07-26 |
Abbvie Biotechnology Ltd |
Methods for determining efficacy of TNF-α inhibitors for treatment of rheumatoid arthritis
|
|
EP2007426A4
(en)
|
2006-04-10 |
2010-06-16 |
Abbott Biotech Ltd |
COMPOSITIONS FOR THE TREATMENT OF PSORIASTIC POLYARTHRITIS AND THEIR APPLICATIONS
|
|
US20090317399A1
(en)
*
|
2006-04-10 |
2009-12-24 |
Pollack Paul F |
Uses and compositions for treatment of CROHN'S disease
|
|
US20080118496A1
(en)
*
|
2006-04-10 |
2008-05-22 |
Medich John R |
Uses and compositions for treatment of juvenile rheumatoid arthritis
|
|
EP2703010A3
(en)
|
2006-04-10 |
2014-08-06 |
AbbVie Biotechnology Ltd |
Uses and compositions for treatment of rheumatoid arthritis
|
|
US20080131374A1
(en)
*
|
2006-04-19 |
2008-06-05 |
Medich John R |
Uses and compositions for treatment of rheumatoid arthritis
|
|
US20110008282A1
(en)
*
|
2006-05-15 |
2011-01-13 |
Xbiotech, Inc. |
IL-1alpha immunization induces autoantibodies protective against atherosclerosis
|
|
CN102580086A
(zh)
*
|
2006-05-22 |
2012-07-18 |
埃克斯生物科技公司 |
使用抗IL-1α抗体治疗癌症
|
|
KR101396797B1
(ko)
|
2006-06-30 |
2014-05-26 |
애브비 바이오테크놀로지 리미티드 |
자동 주사 장치
|
|
AU2007272970C1
(en)
|
2006-07-11 |
2013-01-10 |
Roy C. Levitt |
Rhinosinusitis prevention and therapy with proinflammatory cytokine inhibitors
|
|
US20080014285A1
(en)
*
|
2006-07-13 |
2008-01-17 |
Di Mauro Thomas M |
Method of treating neurodegenerative brain disease with a composite comprising superparamagnetic nanoparticles and a therapeutic compound
|
|
EP3669878A1
(en)
|
2006-08-10 |
2020-06-24 |
Roy C. Levitt |
Localized therapy of lower airways inflammatory disorders with proinflammatory cytokine inhibitors
|
|
WO2008057240A2
(en)
*
|
2006-10-27 |
2008-05-15 |
Abbott Biotechnology Ltd. |
Crystalline anti-htnfalpha antibodies
|
|
CA2681752A1
(en)
*
|
2007-03-29 |
2008-10-09 |
Abbott Laboratories |
Crystalline anti-human 1l-12 antibodies
|
|
EP2068925A4
(en)
|
2007-05-07 |
2011-08-31 |
Medimmune Llc |
ANTI-ICOS ANTIBODIES AND THEIR USE FOR THE TREATMENT OF CANCER, TRANSPLANTATIONS AND AUTOIMMUNE DISEASES
|
|
EP2171451A4
(en)
|
2007-06-11 |
2011-12-07 |
Abbott Biotech Ltd |
METHOD FOR TREATING JUVENILIAN IDIOPATHIC ARTHRITIS
|
|
EP2185201A4
(en)
*
|
2007-08-08 |
2011-11-30 |
Abbott Lab |
COMPOSITIONS AND METHODS FOR CRYSTALLIZING ANTIBODIES
|
|
US20090038182A1
(en)
*
|
2007-08-09 |
2009-02-12 |
Lans Maris J |
Footwear with built-in scale
|
|
US8986696B2
(en)
*
|
2007-12-21 |
2015-03-24 |
Depuy Mitek, Inc. |
Trans-capsular administration of p38 map kinase inhibitors into orthopedic joints
|
|
US20090162351A1
(en)
*
|
2007-12-21 |
2009-06-25 |
Depuy Spine, Inc. |
Transdiscal administration of inhibitors of p38 MAP kinase
|
|
EP2225276B1
(en)
|
2007-12-31 |
2014-04-23 |
Bayer Intellectual Property GmbH |
Antibodies to tnf alpha
|
|
WO2009090189A1
(en)
*
|
2008-01-15 |
2009-07-23 |
Abbott Gmbh & Co.Kg |
Powdered protein compositions and methods of making same
|
|
CA2726345C
(en)
*
|
2008-05-30 |
2018-08-28 |
John Simard |
Interleukin-1 alpha antibodies and methods of use
|
|
AU2009291536B2
(en)
*
|
2008-09-12 |
2012-08-16 |
Xbiotech Inc. |
Targeting pathogenic monocytes
|
|
US8415291B2
(en)
|
2008-10-31 |
2013-04-09 |
Centocor Ortho Biotech Inc. |
Anti-TNF alpha fibronectin type III domain based scaffold compositions, methods and uses
|
|
JP5933975B2
(ja)
|
2008-11-12 |
2016-06-15 |
メディミューン,エルエルシー |
抗体製剤
|
|
KR101721906B1
(ko)
|
2009-04-29 |
2017-03-31 |
애브비 바이오테크놀로지 리미티드 |
자동 주입 장치
|
|
NZ621655A
(en)
|
2009-10-26 |
2015-08-28 |
Nestec Sa |
Assays for the detection of anti-tnf drugs and autoantibodies
|
|
NZ627052A
(en)
|
2009-12-15 |
2015-12-24 |
Abbvie Biotechnology Ltd |
Improved firing button for automatic injection device
|
|
CA2787783A1
(en)
|
2010-01-20 |
2011-07-28 |
Tolerx, Inc. |
Anti-ilt5 antibodies and ilt5-binding antibody fragments
|
|
CA2787755A1
(en)
|
2010-01-20 |
2011-07-28 |
Tolerx, Inc. |
Immunoregulation by anti-ilt5 antibodies and ilt5-binding antibody fragments
|
|
KR102167261B1
(ko)
|
2010-06-18 |
2020-10-20 |
엑스바이오테크, 인크. |
관절염 치료
|
|
US10294296B2
(en)
|
2010-08-23 |
2019-05-21 |
Xbiotech, Inc. |
Treatment for neoplastic diseases
|
|
NZ609363A
(en)
|
2010-10-18 |
2015-04-24 |
Nestec Sa |
Methods for determining anti-drug antibody isotypes
|
|
AR084210A1
(es)
*
|
2010-12-08 |
2013-05-02 |
Abbott Lab |
PROTEINAS DE UNION AL TNF-a
|
|
RU2695566C2
(ru)
|
2011-01-24 |
2019-07-24 |
Эббви Байотекнолоджи Лтд. |
Снятие кожухов иглы со шприцов и автоматических инъекционных устройств
|
|
MX360402B
(es)
|
2011-01-24 |
2018-10-31 |
Abbvie Biotechnology Ltd |
Dispositivos de inyeccion automaticos que tienen superficies de agarre sobremoldeadas.
|
|
DK2676137T3
(en)
|
2011-02-17 |
2015-01-19 |
Nestec Sa |
TESTS TO DETECT AUTO ANTIBODIES FOR ANTI-TNF PHARMACEUTICALS
|
|
CN102675460B
(zh)
|
2011-02-28 |
2015-08-19 |
珠海市丽珠单抗生物技术有限公司 |
抗肿瘤坏死因子α的人源化抗体
|
|
US8658171B2
(en)
|
2011-02-28 |
2014-02-25 |
Livzon Mabpharm Inc. |
Humanized anti-TNFα antibodies
|
|
US9724409B2
(en)
|
2011-04-01 |
2017-08-08 |
Xbiotech, Inc. |
Treatment of inflammatory skin disease
|
|
EP2702077A2
(en)
|
2011-04-27 |
2014-03-05 |
AbbVie Inc. |
Methods for controlling the galactosylation profile of recombinantly-expressed proteins
|
|
MX343324B
(es)
|
2011-07-06 |
2016-11-01 |
Nestec Sa |
Ensayos para detectar auto anticuerpos neutralizadores de la terapia biologica con tnf alpha.
|
|
ES2695102T3
(es)
|
2011-09-23 |
2019-01-02 |
Xbiotech Inc |
Tratamiento para la caquexia
|
|
WO2013063114A1
(en)
|
2011-10-24 |
2013-05-02 |
Abbvie Inc. |
Immunobinders directed against tnf
|
|
AU2012328917B2
(en)
*
|
2011-10-24 |
2017-05-25 |
Abbvie Inc. |
Bispecific immunobinders directed against TNF and IL-17
|
|
WO2013158273A1
(en)
|
2012-04-20 |
2013-10-24 |
Abbvie Inc. |
Methods to modulate c-terminal lysine variant distribution
|
|
US9067990B2
(en)
|
2013-03-14 |
2015-06-30 |
Abbvie, Inc. |
Protein purification using displacement chromatography
|
|
US9150645B2
(en)
|
2012-04-20 |
2015-10-06 |
Abbvie, Inc. |
Cell culture methods to reduce acidic species
|
|
US9249182B2
(en)
|
2012-05-24 |
2016-02-02 |
Abbvie, Inc. |
Purification of antibodies using hydrophobic interaction chromatography
|
|
HK1211981A1
(en)
|
2012-09-02 |
2016-06-03 |
Abbvie Inc. |
Methods to control protein heterogeneity
|
|
US9512214B2
(en)
|
2012-09-02 |
2016-12-06 |
Abbvie, Inc. |
Methods to control protein heterogeneity
|
|
US9545441B2
(en)
|
2012-09-18 |
2017-01-17 |
Xbiotech, Inc. |
Treatment of diabetes
|
|
SG11201507230PA
(en)
|
2013-03-12 |
2015-10-29 |
Abbvie Inc |
Human antibodies that bind human tnf-alpha and methods of preparing the same
|
|
US8921526B2
(en)
|
2013-03-14 |
2014-12-30 |
Abbvie, Inc. |
Mutated anti-TNFα antibodies and methods of their use
|
|
WO2014159554A1
(en)
|
2013-03-14 |
2014-10-02 |
Abbvie Inc. |
Low acidic species compositions and methods for producing the same using displacement chromatography
|
|
US20140271633A1
(en)
|
2013-03-14 |
2014-09-18 |
Abbvie Inc. |
Mammalian cell culture performance through surfactant supplementation of feed media
|
|
WO2014151878A2
(en)
|
2013-03-14 |
2014-09-25 |
Abbvie Inc. |
Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
|
|
US9017687B1
(en)
|
2013-10-18 |
2015-04-28 |
Abbvie, Inc. |
Low acidic species compositions and methods for producing and using the same using displacement chromatography
|
|
CA2926301A1
(en)
|
2013-03-14 |
2014-10-02 |
Abbvie Inc. |
Low acidic species compositions and methods for producing and using the same
|
|
KR102216003B1
(ko)
|
2013-03-15 |
2021-02-16 |
얀센 바이오테크 인코포레이티드 |
재조합 단백질에서 c-말단 라이신, 갈락토스 및 시알산 함량을 제어하기 위한 제조 방법
|
|
US9598667B2
(en)
|
2013-10-04 |
2017-03-21 |
Abbvie Inc. |
Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
|
|
US9085618B2
(en)
|
2013-10-18 |
2015-07-21 |
Abbvie, Inc. |
Low acidic species compositions and methods for producing and using the same
|
|
US9181337B2
(en)
|
2013-10-18 |
2015-11-10 |
Abbvie, Inc. |
Modulated lysine variant species compositions and methods for producing and using the same
|
|
US8946395B1
(en)
|
2013-10-18 |
2015-02-03 |
Abbvie Inc. |
Purification of proteins using hydrophobic interaction chromatography
|
|
US20150139988A1
(en)
|
2013-11-15 |
2015-05-21 |
Abbvie, Inc. |
Glycoengineered binding protein compositions
|
|
WO2015198320A1
(en)
|
2014-06-24 |
2015-12-30 |
Insight Biopharmaceuticals Ltd. |
Methods of purifying antibodies
|
|
US20170226552A1
(en)
|
2014-07-03 |
2017-08-10 |
Abbvie Inc. |
Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using cobalt
|
|
WO2016007764A1
(en)
|
2014-07-09 |
2016-01-14 |
Abbvie Inc. |
Methods for modulating the glycosylation profile of recombinant proteins using non-commonly used sugars
|
|
WO2016088104A2
(en)
|
2014-12-05 |
2016-06-09 |
Nestec S.A. |
Indirect homogeneous mobility shift assays for the detection of biologics in patient samples
|
|
EP3078675A1
(en)
|
2015-04-10 |
2016-10-12 |
Ares Trading S.A. |
Induction dosing regimen for the treatment of tnf alpha mediated disorders
|
|
US10465003B2
(en)
|
2016-02-05 |
2019-11-05 |
Janssen Biotech, Inc. |
Anti-TNF antibodies, compositions, methods and use for the treatment or prevention of type 1 diabetes
|
|
JOP20190162A1
(ar)
|
2016-12-30 |
2019-06-27 |
Biocad Joint Stock Co |
تركيبة صيدلانية مائية من جسم مضاد لـ tnf? أحادي النسيلة معاود الارتباط الجيني
|
|
KR20190113858A
(ko)
|
2017-01-30 |
2019-10-08 |
얀센 바이오테크 인코포레이티드 |
활성 건선성 관절염의 치료를 위한 항-tnf 항체, 조성물, 및 방법
|
|
MA47442A
(fr)
|
2017-02-07 |
2019-12-18 |
Janssen Biotech Inc |
Anticorps anti-tnf, compositions et méthodes pour le traitement de la spondylarthrite ankylosante active
|
|
CA3053231A1
(en)
|
2017-02-16 |
2018-08-23 |
Xbiotech Inc. |
Treatment of hidradenitis suppurativa
|
|
MA54750A
(fr)
|
2019-01-15 |
2021-11-24 |
Janssen Biotech Inc |
Compositions d'anticorps anti-tnf et procédés pour le traitement de l'arthrite idiopathique juvénile
|
|
BR112021014267A2
(pt)
|
2019-01-23 |
2022-02-15 |
Janssen Biotech Inc |
Composições de anticorpo anti-tnf e métodos para o tratamento de artrite psoriática
|
|
CA3133381A1
(en)
|
2019-03-14 |
2020-09-17 |
Janssen Biotech, Inc. |
Manufacturing methods for producing anti-tnf antibody compositions
|
|
JP7662529B2
(ja)
|
2019-03-14 |
2025-04-15 |
ヤンセン バイオテツク,インコーポレーテツド |
抗tnf抗体組成物を産生するための方法
|
|
KR20210141976A
(ko)
|
2019-03-14 |
2021-11-23 |
얀센 바이오테크 인코포레이티드 |
항-tnf 항체 조성물의 제조 방법
|
|
WO2020234834A1
(en)
|
2019-05-23 |
2020-11-26 |
Janssen Biotech, Inc. |
Method of treating inflammatory bowel disease with a combination therapy of antibodies to il-23 and tnf alpha
|
|
US20220324959A1
(en)
|
2019-06-03 |
2022-10-13 |
Janssen Biotech, Inc. |
Anti-tnf antibodies, compositions, and methods for the treatment of active ankylosing spondylitis
|
|
MA56015A
(fr)
|
2019-06-03 |
2022-04-06 |
Janssen Biotech Inc |
Compositions d'anticorps anti-tnf et méthodes pour le traitement de l'arthrite psoriasique
|
|
EP3990922A1
(en)
|
2019-06-25 |
2022-05-04 |
ProciseDx Inc. |
Detection of anti-tnf alpha drug biologics and anti-drug antibodies
|
|
WO2021028752A1
(en)
|
2019-08-15 |
2021-02-18 |
Janssen Biotech, Inc. |
Anti-tfn antibodies for treating type i diabetes
|
|
KR20230023663A
(ko)
|
2020-05-21 |
2023-02-17 |
얀센 바이오테크 인코포레이티드 |
Il-23 및 tnf 알파에 대한 항체의 병용 요법으로 염증성 장질환을 치료하는 방법
|
|
CA3095676A1
(en)
|
2020-10-07 |
2022-04-07 |
Xbiotech Inc. |
True human antibody specific for interleukin 1 alpha (il-1a)
|
|
CA3095679A1
(en)
|
2020-10-07 |
2022-04-07 |
Xbiotech Inc. |
True human antibody specific for interleuken 1 alpha (il-1a)
|
|
CA3095675A1
(en)
|
2020-10-07 |
2022-04-07 |
Xbiotech Inc. |
True human antibody specific for interleukin 1 alpha (il-1a)
|
|
CA3095740A1
(en)
|
2020-10-07 |
2022-04-07 |
Xbiotech Inc. |
True human antibody specific for interleukin alpha (il-1a)
|
|
JP2023551542A
(ja)
|
2020-11-30 |
2023-12-08 |
エニグマ バイオインテリジェンス,インコーポレイテッド |
アルツハイマー病の非侵襲的評価
|
|
JP7688150B2
(ja)
|
2020-12-09 |
2025-06-03 |
エイチケー イノ.エヌ コーポレーション |
抗OX40L抗体、抗OX40L及び抗TNFαの二重特異性抗体、並びにこれらの用途
|
|
IL309997A
(en)
|
2021-07-09 |
2024-03-01 |
Janssen Biotech Inc |
Production methods for the production of anti-TNF antibody compositions
|
|
AU2022308201A1
(en)
|
2021-07-09 |
2024-02-22 |
Janssen Biotech, Inc. |
Manufacturing methods for producing anti-tnf antibody compositions
|