ES2058121T3 - Preparacion enzimatica inmovilizada y su uso. - Google Patents

Preparacion enzimatica inmovilizada y su uso.

Info

Publication number
ES2058121T3
ES2058121T3 ES87307979T ES87307979T ES2058121T3 ES 2058121 T3 ES2058121 T3 ES 2058121T3 ES 87307979 T ES87307979 T ES 87307979T ES 87307979 T ES87307979 T ES 87307979T ES 2058121 T3 ES2058121 T3 ES 2058121T3
Authority
ES
Spain
Prior art keywords
preparation
immobilized
glycine
enzymatic
enzymatic preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87307979T
Other languages
English (en)
Inventor
Lawson William Powell
John Anthony Power
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB868622389A external-priority patent/GB8622389D0/en
Priority claimed from GB868623306A external-priority patent/GB8623306D0/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Application granted granted Critical
Publication of ES2058121T3 publication Critical patent/ES2058121T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/009—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving hydantoins or carbamoylamino compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/091—Phenol resins; Amino resins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/14—Enzymes or microbial cells immobilised on or in an inorganic carrier
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

UNA PREPARACION DE ENZIMA ESTABILIZADA QUE COMPRENDE UNA HIDANTOINASA INMOVILIZADA ES UTIL PARA LA PREPARACION DE UNA D (-) (OPCIONALMENTE FENIL SUSTITUIDA GLICINA O UN DERIVADO N-CARBAMOILO DE LA MISMA POR HIDROLISIS DE UNA 5-(OPCIONALMENTE FENIL SUSTITUIDA) HIDANTOINA. LA PREPARACION ENZIMATICA COMPRENDE CELULAS O CELULAS TRATADAS DE UN ORGANISMO PRODUCTOR DE HIDANTOINASA INMOVILIZADO DENTRO O SOBRE UN SOPORTE SOLIDO, O UNA ENZIMA DERIVADA DEL ORGANISMO ABSORBIDO SOBRE O LIGADO AUN SOPORTE POLIMERICO, JUNTO CON IONES METALICOS DIVALENTES QUE ESTABILIZAN LA PREPARACION Y LA VUELVEN CAPAZ DE REUTILIZACION. PROCESOS PARA OBTENER LA PREPARACION ENZIMATICA Y PARA UTILIZARLA PARA PREPARAR PRODUCTOS FINALES IMPORTANTES COMERCIALMENTE TALES COMO D8-) (4-HIDROXIFENIL) GLICINA.
ES87307979T 1986-09-17 1987-09-09 Preparacion enzimatica inmovilizada y su uso. Expired - Lifetime ES2058121T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868622389A GB8622389D0 (en) 1986-09-17 1986-09-17 Preparation
GB868623306A GB8623306D0 (en) 1986-09-27 1986-09-27 Preparation

Publications (1)

Publication Number Publication Date
ES2058121T3 true ES2058121T3 (es) 1994-11-01

Family

ID=26291302

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87307979T Expired - Lifetime ES2058121T3 (es) 1986-09-17 1987-09-09 Preparacion enzimatica inmovilizada y su uso.

Country Status (10)

Country Link
EP (1) EP0261836B1 (es)
JP (1) JPH0779696B2 (es)
AU (1) AU603827B2 (es)
CA (1) CA1298800C (es)
DE (1) DE3786511T2 (es)
DK (1) DK170992B1 (es)
ES (1) ES2058121T3 (es)
IE (1) IE60591B1 (es)
NZ (1) NZ221808A (es)
PT (1) PT85718B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0515698B1 (en) * 1990-12-07 1998-07-29 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Process for producing D-alpha-amino acids
ES2042409B1 (es) * 1992-04-10 1994-06-01 Control & Gestion Instr Procedimiento para la preparacion de d-aminoacidos o derivados de d-aminoacidos.
EP0725142B1 (en) * 1994-06-24 2003-09-10 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Process for producing d-amino acid by using composite immobilized enzyme preparation
EP0801131B1 (en) * 1994-12-28 2007-02-21 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Process for producing d-n-carbamoyl-alpha-amino acid
AU2241799A (en) * 1998-01-26 1999-08-09 Pharm-Eco Laboratories, Inc. Enzyme activated supports for enantiomeric separations
DE10130169A1 (de) * 2001-06-22 2003-01-09 Degussa Aktivierte rec-D-Hydantoinasen
WO2011003702A1 (en) * 2009-07-09 2011-01-13 Dsm Ip Assets B.V. Stabilized enzyme compositions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH596313A5 (es) * 1975-05-30 1978-03-15 Battelle Memorial Institute
IT1039757B (it) * 1975-07-10 1979-12-10 Snam Progetti Complessi enzimatici atti a trasformare idantoine raceme in am minoacidi otticamente attivi e loro applicazione
US4094741A (en) * 1976-02-04 1978-06-13 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Process for preparing D-(-)-N-carbamoyl-2-(phenyl or substituted phenyl)glycines
US4211840A (en) * 1977-06-08 1980-07-08 Ajinomoto Company, Incorporated Method for producing D-α-amino acid
GB2122621B (en) * 1982-06-25 1985-09-25 Uop Inc Enhanced immobilization of glucose isomerase

Also Published As

Publication number Publication date
DE3786511D1 (de) 1993-08-19
JPS63185382A (ja) 1988-07-30
CA1298800C (en) 1992-04-14
EP0261836A1 (en) 1988-03-30
IE60591B1 (en) 1994-07-27
HK1003230A1 (en) 1998-10-16
EP0261836B1 (en) 1993-07-14
PT85718B (pt) 1990-08-31
PT85718A (en) 1987-10-01
DK483487A (da) 1988-03-18
DE3786511T2 (de) 1994-01-13
IE872497L (en) 1988-03-17
DK170992B1 (da) 1996-04-15
DK483487D0 (da) 1987-09-15
JPH0779696B2 (ja) 1995-08-30
NZ221808A (en) 1989-02-24
AU603827B2 (en) 1990-11-29
AU7843287A (en) 1988-03-24

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