ES2058288T3 - Composiciones de ibuprofen secadas por atomizacion. - Google Patents
Composiciones de ibuprofen secadas por atomizacion.Info
- Publication number
- ES2058288T3 ES2058288T3 ES88306003T ES88306003T ES2058288T3 ES 2058288 T3 ES2058288 T3 ES 2058288T3 ES 88306003 T ES88306003 T ES 88306003T ES 88306003 T ES88306003 T ES 88306003T ES 2058288 T3 ES2058288 T3 ES 2058288T3
- Authority
- ES
- Spain
- Prior art keywords
- ibuprofen
- atomization
- compositions
- dried
- spray dried
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 title abstract 4
- 229960001680 ibuprofen Drugs 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000000889 atomisation Methods 0.000 title 1
- 229920000881 Modified starch Polymers 0.000 abstract 1
- 238000007907 direct compression Methods 0.000 abstract 1
- 239000007884 disintegrant Substances 0.000 abstract 1
- 239000007921 spray Substances 0.000 abstract 1
- 238000010922 spray-dried dispersion Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
- 239000000080 wetting agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
UNA COMPOSICION DE IBUPROFEN SECADA POR PULVERIZACION, ADECUADA PARA COMPRESION DIRECTA A PASTILLAS, QUE COMPRENDE UNA DISPERDION EN AGUA DE IBUPROFEN, ALMIDON PREGELATINIZADO, UN DESINTEGRANTE Y UN AGENTE HUMECTANTE DEL IBUPROFEN, SECADA POR DISPERSION.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7111687A | 1987-07-08 | 1987-07-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2058288T3 true ES2058288T3 (es) | 1994-11-01 |
Family
ID=22099338
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES88306003T Expired - Lifetime ES2058288T3 (es) | 1987-07-08 | 1988-07-01 | Composiciones de ibuprofen secadas por atomizacion. |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0298666B1 (es) |
| AT (1) | ATE92752T1 (es) |
| DE (1) | DE3883098T2 (es) |
| ES (1) | ES2058288T3 (es) |
| IE (1) | IE61676B1 (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5047246A (en) * | 1988-09-09 | 1991-09-10 | Bristol-Myers Company | Direct compression cyclophosphamide tablet |
| PT96229B (pt) * | 1989-12-22 | 1998-06-30 | Syntex Pharma Int | Processo para a preparacao de composicoes farmaceuticas em po, secas por pulverizacao, directamente compressiveis em comprimidos, contendo naproxeno ou naproxeno sodico |
| WO1991016886A1 (en) * | 1990-05-03 | 1991-11-14 | G.D. Searle & Co. | Pharmaceutical composition containing ibuprofen and a prostaglandin |
| GB9119052D0 (en) * | 1991-09-06 | 1991-10-23 | Boots Co Plc | Pharmaceutical compositions |
| DE69520292T2 (de) * | 1994-12-14 | 2001-06-13 | Bioglan Ireland (R & D) Ltd., Dublin | Pharmazeutische zubereitung zur direktverpressung |
| US6726929B1 (en) | 1998-12-18 | 2004-04-27 | Basf Aktiengesellschaft | Pharmaceutical mixture comprising a profen |
| HUP0104606A3 (en) * | 1998-12-18 | 2003-01-28 | Basf Ag | A pharmaceutical mixture comprising a profen |
| US6251945B1 (en) * | 1999-01-14 | 2001-06-26 | Knoll Aktiengesellschaft | Pharmaceutical mixture comprising a combination of a profen and other active compounds |
| US6093715A (en) * | 1999-03-24 | 2000-07-25 | Basf Aktiengesellschaft | Process for producing riboflavin-containing granules |
| EP1765296A2 (en) * | 2004-06-30 | 2007-03-28 | Albemarle Corporation | High ibuprofen content granules and their preparation and use |
| DK1848430T3 (da) | 2004-12-31 | 2017-11-06 | Dr Reddys Laboratories Ltd | Nye benzylamin-derivativer som cetp-inhibitors |
| US8604055B2 (en) | 2004-12-31 | 2013-12-10 | Dr. Reddy's Laboratories Ltd. | Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors |
| EP1850842A1 (de) * | 2005-02-11 | 2007-11-07 | Stada Arzneimittel Ag | Pharmazeutische zusammensetzungen nebivolo und ein hydrophiles polymer |
| CA2845284C (en) | 2011-08-18 | 2018-03-06 | Dr. Reddy's Laboratories Ltd. | Substituted heterocyclic amine compounds as cholesteryl ester-transfer protein (cetp) inhibitors |
| JP6140168B2 (ja) | 2011-09-27 | 2017-05-31 | ドクター レディズ ラボラトリーズ リミテッド | アテローム性動脈硬化症の処置のために有用なコレステリルエステル転送タンパク質(cetp)インヒビターとしての5−ベンジルアミノメチル−6−アミノピラゾロ[3,4−b]ピリジン誘導体 |
| CA2891502A1 (en) * | 2012-11-19 | 2014-05-22 | Dr. Reddy's Laboratories Ltd. | Pharmaceutical compositions of cetp inhibitors |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0040472B1 (en) * | 1980-05-20 | 1986-01-29 | Mallinckrodt, Inc. (a Delaware corporation) | Spray dried n-acetyl-p-aminophenol compositions and method for manufacture thereof |
| AR226763A1 (es) * | 1980-12-22 | 1982-08-13 | Monsanto Co | Metodo de preparacion de una granulacion analgesica de acetaminofeno |
| US4369308A (en) * | 1981-07-24 | 1983-01-18 | National Starch And Chemical Corporation | Low swelling starches as tablet disintegrants |
| US4600579A (en) * | 1983-06-07 | 1986-07-15 | Mallinckrodt, Inc. | N-acetyl-p-aminophenol compositions containing partially gelatinized starch and method for preparing same |
| JPH0647532B2 (ja) * | 1983-08-31 | 1994-06-22 | ジ アツプジヨン カンパニ− | 歯槽骨吸収の治療 |
| US4551177A (en) * | 1984-04-23 | 1985-11-05 | National Starch And Chemical Corporation | Compressible starches as binders for tablets or capsules |
| US4609675A (en) * | 1984-08-17 | 1986-09-02 | The Upjohn Company | Stable, high dose, high bulk density ibuprofen granulations for tablet and capsule manufacturing |
| DE3522550A1 (de) * | 1985-06-24 | 1987-01-02 | Klinge Co Chem Pharm Fab | Aufspruehbare pharmazeutische zubereitung fuer die topische anwendung |
-
1988
- 1988-07-01 DE DE88306003T patent/DE3883098T2/de not_active Expired - Fee Related
- 1988-07-01 AT AT88306003T patent/ATE92752T1/de not_active IP Right Cessation
- 1988-07-01 IE IE202088A patent/IE61676B1/en not_active IP Right Cessation
- 1988-07-01 EP EP19880306003 patent/EP0298666B1/en not_active Expired - Lifetime
- 1988-07-01 ES ES88306003T patent/ES2058288T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE3883098T2 (de) | 1993-12-02 |
| IE882020L (en) | 1989-01-08 |
| ATE92752T1 (de) | 1993-08-15 |
| IE61676B1 (en) | 1994-11-30 |
| EP0298666A2 (en) | 1989-01-11 |
| DE3883098D1 (de) | 1993-09-16 |
| EP0298666A3 (en) | 1989-05-17 |
| EP0298666B1 (en) | 1993-08-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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